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      "sourceType": "Review",
      "title": "Quantum Chemistry in the Age of Quantum Computing.",
      "authors": "Cao Y, Romero J, Olson JP, Degroote M, Johnson PD, Kieferová M, Kivlichan ID, Menke T, Peropadre B, Sawaya NPD, Sim S, Veis L, Aspuru-Guzik A.",
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      "title": "VQE method: a short survey and recent developments",
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      "originalCitation": "Fedorov DA et al. (2022). \"VQE method: A short survey and recent developments.\" Materials Theory 6:2",
      "originalSection": "Quantum Computing in Genomics",
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      "sourceType": "Review",
      "title": "Heart Rate Variability: New Perspectives on Physiological Mechanisms, Assessment of Self-regulatory Capacity, and Health risk.",
      "authors": "McCraty R, Shaffer F.",
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      "originalCitation": "McCraty R, Shaffer F (2015). \"Heart Rate Variability: New Perspectives on Physiological Mechanisms, Assessment of Self-regulatory Capacity, and Health Risk.\" Global Advances in Health and Medicine 4(1):46–61",
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      "corrections": [],
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    {
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      "sourceType": "Journal publication",
      "title": "Heart rate variability biofeedback: how and why does it work?",
      "authors": "Lehrer PM, Gevirtz R.",
      "year": 2014,
      "journal": "Frontiers in psychology",
      "doi": "10.3389/fpsyg.2014.00756",
      "pmid": "25101026",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Lehrer PM, Gevirtz R (2014). \"Heart rate variability biofeedback: how and why does it work?\" Frontiers in Psychology 5:756",
      "originalSection": "Prescription Sound / Biofeedback",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
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    {
      "ref": "NPL-18",
      "recordId": "hsi-4c43fe26667b32",
      "sourceType": "Conference publication",
      "title": "MedRec: Using Blockchain for Medical Data Access and Permission Management",
      "authors": "Asaph Azaria; Ariel Ekblaw; Thiago Vieira; Andrew Lippman",
      "year": 2016,
      "journal": "2016 2nd International Conference on Open and Big Data (OBD)",
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      "originalCitation": "Azaria A, Ekblaw A, Vieira T, Lippman A (2016). \"MedRec: Using Blockchain for Medical Data Access and Permission Management.\" IEEE 2nd International Conference on Open and Big Data",
      "originalSection": "Blockchain-Based Mental Health Rewards",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
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    },
    {
      "ref": "NPL-19",
      "recordId": "pmid-22824810",
      "sourceType": "Journal publication",
      "title": "Evidence for the existence of dopamine D2-oxytocin receptor heteromers in the ventral and dorsal striatum with facilitatory receptor-receptor interactions.",
      "authors": "Romero-Fernandez W, Borroto-Escuela DO, Agnati LF, Fuxe K.",
      "year": 2013,
      "journal": "Molecular psychiatry",
      "doi": "10.1038/mp.2012.103",
      "pmid": "22824810",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Romero-Fernandez W, Borroto-Escuela DO, Agnati LF, Fuxe K (2013). \"Evidence for the existence of dopamine D2-oxytocin receptor heteromers in the ventral and dorsal striatum with facilitatory receptor–receptor interactions.\" Molecular Psychiatry 18:849–850",
      "originalSection": "OXTR Modulation of DRD2/SLC6A4",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.nature.com/articles/mp2012103",
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      "corrections": [],
      "topicId": null,
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    },
    {
      "ref": "NPL-20",
      "recordId": "hsi-8e4034b8b289a9",
      "sourceType": "Journal publication",
      "title": "The oxytocin receptor rs2254298 polymorphism and alcohol withdrawal symptoms: a gene-environment interaction in mood disorders.",
      "authors": "Shen G, Yang S, Wu L, Chen Y, Hu Y, Zhou F, Wang W, Liu P, Wu F, Liu Y, Wang F, Chen L.",
      "year": 2023,
      "journal": "Frontiers in psychiatry",
      "doi": "10.3389/fpsyt.2023.1085429",
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      "originalCitation": "Chen L et al. (2023). \"The oxytocin receptor rs2254298 polymorphism and alcohol withdrawal symptoms: a gene–environment interaction in mood disorders.\" Frontiers in Psychiatry 14:1085429",
      "originalSection": "OXTR Modulation of DRD2/SLC6A4",
      "metadataStatus": "metadata-matched",
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      "corrections": [],
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    {
      "ref": "NPL-21",
      "recordId": "hsi-3d163ae87207d0",
      "sourceType": "Journal publication",
      "title": "The Role of Oxytocin and Oxytocin Gene Receptor Methylation During Withdrawal Therapy in Males With Alcohol Use Disorder.",
      "authors": "Proskynitopoulos PJ, Haarmeyer AF, Bleich S, Frieling H, Hillemacher T, Glahn A, Rhein M.",
      "year": 2025,
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      "originalAssignee": null,
      "originalCitation": "Geisel O et al. (2025). \"The Role of Oxytocin and Oxytocin Gene Receptor Methylation During Withdrawal Therapy in Males With Alcohol Use Disorder.\" Alcoholism: Clinical and Experimental Research (PMC12257889)",
      "originalSection": "OXTR Modulation of DRD2/SLC6A4",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    },
    {
      "ref": "NPL-22",
      "recordId": "hsi-28e5e7fe09245a",
      "sourceType": "Journal publication",
      "title": "Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting.",
      "authors": "Bakermans-Kranenburg MJ, van Ijzendoorn MH.",
      "year": 2008,
      "journal": "Social cognitive and affective neuroscience",
      "doi": "10.1093/scan/nsn004",
      "pmid": "19015103",
      "pmcid": "PMC2555463",
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      "originalCitation": "Bakermans-Kranenburg MJ, van Ijzendoorn MH (2008). \"Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting.\" Social Cognitive and Affective Neuroscience 3(2):128–134",
      "originalSection": "OXTR Modulation of DRD2/SLC6A4",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [],
      "topicId": null,
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    },
    {
      "ref": "NPL-23",
      "recordId": "hsi-d6215fd15c4e25",
      "sourceType": "Journal publication",
      "title": "Interaction of 5-HTTLPR and a variation on the oxytocin receptor gene influences negative emotionality.",
      "authors": "Montag C, Fiebach CJ, Kirsch P, Reuter M.",
      "year": 2011,
      "journal": "Biological psychiatry",
      "doi": "10.1016/j.biopsych.2010.10.026",
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      "originalAssignee": null,
      "originalCitation": "Montag C, Fiebach CJ, Kirsch P, Reuter M (2011). \"Interaction of 5-HTTLPR and a Variation on the Oxytocin Receptor Gene Influences Negative Emotionality.\" Biological Psychiatry 69(6):601–603",
      "originalSection": "OXTR Modulation of DRD2/SLC6A4",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-24",
      "recordId": "hsi-6b1d2def31c0db",
      "sourceType": "Journal publication",
      "title": "Variation in the oxytocin receptor gene is associated with behavioral and neural correlates of empathic accuracy.",
      "authors": "Laursen HR, Siebner HR, Haren T, Madsen K, Grønlund R, Hulme O, Henningsson S.",
      "year": 2014,
      "journal": "Frontiers in behavioral neuroscience",
      "doi": "10.3389/fnbeh.2014.00423",
      "pmid": "25538588",
      "pmcid": "PMC4257152",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Tong WH et al. (2014). \"Variation in the oxytocin receptor gene is associated with behavioral and neural correlates of empathic accuracy.\" Frontiers in Behavioral Neuroscience 8:423",
      "originalSection": "OXTR Modulation of DRD2/SLC6A4",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    },
    {
      "ref": "NPL-25",
      "recordId": "pmid-33071746",
      "sourceType": "Review",
      "title": "Oxytocin Receptor Signaling in Vascular Function and Stroke.",
      "authors": "McKay EC, Counts SE.",
      "year": 2020,
      "journal": "Frontiers in neuroscience",
      "doi": "10.3389/fnins.2020.574499",
      "pmid": "33071746",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Gutkowska J, Jankowski M (2020). \"Oxytocin Receptor Signaling in Vascular Function and Stroke.\" Frontiers in Neuroscience 14:574499 (PMC 7544744)",
      "originalSection": "OXTR Influence on Facial Microcirculation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
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    {
      "ref": "NPL-26",
      "recordId": "hsi-55916122662aa4",
      "sourceType": "Journal publication",
      "title": "Oxytocin modulates proliferation and stress responses of human skin cells: implications for atopic dermatitis.",
      "authors": "Deing V, Roggenkamp D, Kühnl J, Gruschka A, Stäb F, Wenck H, Bürkle A, Neufang G.",
      "year": 2013,
      "journal": "Experimental dermatology",
      "doi": "10.1111/exd.12155",
      "pmid": "23711064",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Deing V et al. (2012). \"Oxytocin modulates proliferation and stress responses of human skin cells.\" Experimental Dermatology (PMID 23711064)",
      "originalSection": "OXTR Influence on Facial Microcirculation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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        "Published title reconciled with the metadata record."
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      "topicId": "optical-physiology",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-27",
      "recordId": "hsi-aecb6ce44b1875",
      "sourceType": "Journal publication",
      "title": "Structural basis for the activation and ligand recognition of the human oxytocin receptor.",
      "authors": "Waltenspühl Y, Ehrenmann J, Vacca S, Thom C, Medalia O, Plückthun A.",
      "year": 2022,
      "journal": "Nature communications",
      "doi": "10.1038/s41467-022-31325-0",
      "pmid": "35851571",
      "pmcid": "PMC9293896",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Yin J et al. (2022). \"Structural basis for the activation and ligand recognition of the human oxytocin receptor.\" Nature Communications 13:4153",
      "originalSection": "OXTR Influence on Facial Microcirculation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-28",
      "recordId": "hsi-b2ec2b67bc699b",
      "sourceType": "Review",
      "title": "Advances in human oxytocin measurement: challenges and proposed solutions.",
      "authors": "Tabak BA, Leng G, Szeto A, Parker KJ, Verbalis JG, Ziegler TE, Lee MR, Neumann ID, Mendez AJ.",
      "year": 2023,
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      "originalAssignee": null,
      "originalCitation": "Tabak BA et al. (2023). \"Advances in human oxytocin measurement: challenges and proposed solutions.\" Molecular Psychiatry (Nature) 28:1–14",
      "originalSection": "OXTR Influence on Facial Microcirculation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-29",
      "recordId": "pmid-36618821",
      "sourceType": "Review",
      "title": "The oxytocin receptor represents a key hub in the GPCR heteroreceptor network: potential relevance for brain and behavior.",
      "authors": "Borroto-Escuela DO, Cuesta-Marti C, Lopez-Salas A, Chruścicka-Smaga B, Crespo-Ramírez M, Tesoro-Cruz E, Palacios-Lagunas DA, Perez de la Mora M, Schellekens H, Fuxe K.",
      "year": 2022,
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      "doi": "10.3389/fnmol.2022.1055344",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Busnelli M, Bhatt S (2022). \"The oxytocin receptor represents a key hub in the GPCR signaling network.\" Frontiers in Endocrinology (PMC 9812438)",
      "originalSection": "OXTR Influence on Facial Microcirculation",
      "metadataStatus": "metadata-reconciled",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-30",
      "recordId": "hsi-11aecd75cd9043",
      "sourceType": "Review",
      "title": "The Multifaceted Role of Oxytocinergic System and <i>OXTR</i> Gene.",
      "authors": "Hasan R.",
      "year": 2024,
      "journal": "Global medical genetics",
      "doi": "10.1055/s-0044-1779039",
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      "originalCitation": "Cataldo I et al. (2024). \"The Multifaceted Role of Oxytocinergic System and OXTR Gene.\" International Journal of Molecular Sciences (PMC 10796195)",
      "originalSection": "OXTR Influence on Facial Microcirculation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Published title reconciled with the metadata record.",
        "Author attribution differs from the public metadata; canonical authors are shown in source details."
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      "topicId": "optical-physiology",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-31",
      "recordId": "pmid-11792664",
      "sourceType": "Journal publication",
      "title": "Baroreflex control of heart rate by oxytocin in the solitary-vagal complex.",
      "authors": "Higa KT, Mori E, Viana FF, Morris M, Michelini LC.",
      "year": 2002,
      "journal": "American journal of physiology. Regulatory, integrative and comparative physiology",
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      "pmid": "11792664",
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      "originalCitation": "Higa KT et al. (2002). \"Baroreflex control of heart rate by oxytocin in the solitary-vagal complex.\" American Journal of Physiology – Regulatory, Integrative and Comparative Physiology 282(2):R537–R545 (PMID 11792664)",
      "originalSection": "Baroreflex Modulation by Oxytocin",
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      "claimReview": "Not independently appraised",
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    {
      "ref": "NPL-32",
      "recordId": "pmid-27790154",
      "sourceType": "Journal publication",
      "title": "Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus Preautonomic Neurons and Correlates with Baroreflex Impairment in Rats.",
      "authors": "De Melo VU, Saldanha RR, Dos Santos CR, De Campos Cruz J, Lira VA, Santana-Filho VJ, Michelini LC.",
      "year": 2016,
      "journal": "Frontiers in physiology",
      "doi": "10.3389/fphys.2016.00461",
      "pmid": "27790154",
      "pmcid": "PMC5063006",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Martins AS et al. (2016). \"Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus.\" Frontiers in Physiology (PMC 5063006)",
      "originalSection": "Baroreflex Modulation by Oxytocin",
      "metadataStatus": "metadata-reconciled",
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      "topicId": "optical-physiology",
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      "title": "Investigation on the influence of the skin tone on hyperspectral imaging for free flap surgery.",
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      "sourceType": "Journal publication",
      "title": "Detecting Happiness Using Hyperspectral Imaging Technology.",
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      "title": "A novel role of oxytocin: Oxytocin-induced well-being in humans.",
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      "originalCitation": "Ishak WW et al. (2011). \"A novel role of oxytocin: Oxytocin-induced well-being in humans.\" International Journal of Psychiatry in Medicine (PMC 6784812)",
      "originalSection": "OXTR Influence on Facial Microcirculation",
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      "sourceType": "Journal publication",
      "title": "Effects of chronic intranasal oxytocin on visual attention to faces vs. natural scenes in older adults.",
      "authors": "Shoenfelt A, Pehlivanoglu D, Lin T, Ziaei M, Feifel D, Ebner NC.",
      "year": 2024,
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      "originalCitation": "Peled-Avron L et al. (2024). \"Effects of chronic intranasal oxytocin on visual attention to faces.\" Psychopharmacology (PMC 11699979)",
      "originalSection": "OXTR Influence on Facial Microcirculation",
      "metadataStatus": "metadata-matched",
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    {
      "ref": "NPL-53",
      "recordId": "hsi-a6d1ba2316c08d",
      "sourceType": "Journal publication",
      "title": "Effects of Oxytocin on Facial Expression and Identity Working Memory Are Found in Females but Not Males.",
      "authors": "Yue T, Yue C, Liu G, Huang X.",
      "year": 2018,
      "journal": "Frontiers in neuroscience",
      "doi": "10.3389/fnins.2018.00205",
      "pmid": "29719496",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Gao S et al. (2018). \"Effects of Oxytocin on Facial Expression and Identity Working Memory.\" Frontiers in Pharmacology (PMC 5913342)",
      "originalSection": "OXTR Influence on Facial Microcirculation",
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    {
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      "recordId": "hsi-2d570b00f2ccf3",
      "sourceType": "Review",
      "title": "The Role of Oxytocin in Cardiovascular Protection.",
      "authors": "Jankowski M, Broderick TL, Gutkowska J.",
      "year": 2020,
      "journal": "Frontiers in psychology",
      "doi": "10.3389/fpsyg.2020.02139",
      "pmid": "32982875",
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      "originalCitation": "Jankowski M et al. (2020). \"The Role of Oxytocin in Cardiovascular Protection.\" Frontiers in Psychology 11:2139",
      "originalSection": "OXTR Influence on Facial Microcirculation",
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    {
      "ref": "NPL-55",
      "recordId": "hsi-688691ea42776f",
      "sourceType": "Journal publication",
      "title": "Hyperspectral imaging for non-invasive blood oxygen saturation assessment",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Zhang Y et al. (2024). \"Hyperspectral imaging for non-invasive blood oxygen saturation measurement.\" Computers in Biology and Medicine",
      "originalSection": "Detectability by HSI / Optical Imaging",
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    {
      "ref": "NPL-56",
      "recordId": "hsi-fdb97b4e29c7dd",
      "sourceType": "Bibliographic source",
      "title": "Evaluation of hyperspectral imaging to quantify perfusion changes",
      "authors": null,
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      "originalCitation": "Hellmann T et al. (2023). \"Evaluation of hyperspectral imaging to quantify perfusion changes.\" Lasers in Surgery and Medicine 55(5):468–476",
      "originalSection": "Detectability by HSI / Optical Imaging",
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    {
      "ref": "NPL-57",
      "recordId": "hsi-62d3aa9212928c",
      "sourceType": "Journal publication",
      "title": "Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication.",
      "authors": "Goodman RP, Schaap IA, Tardin CF, Erben CM, Berry RM, Schmidt CF, Turberfield AJ.",
      "year": 2005,
      "journal": "Science (New York, N.Y.)",
      "doi": "10.1126/science.1120367",
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      "originalCitation": "Goodman RP, Schaap IAT, Tardin CF et al. (2005). \"Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication.\" Science 310(5754):1661–1665 — Landmark: Turberfield's original single-step DNA tetrahedron self-assembly",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
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    {
      "ref": "NPL-58",
      "recordId": "hsi-25d9dbb27793f1",
      "sourceType": "Journal publication",
      "title": "Self-assembled multivalent DNA nanostructures for noninvasive intracellular delivery of immunostimulatory CpG oligonucleotides.",
      "authors": "Li J, Pei H, Zhu B, Liang L, Wei M, He Y, Chen N, Li D, Huang Q, Fan C.",
      "year": 2011,
      "journal": "ACS nano",
      "doi": "10.1021/nn202774x",
      "pmid": "21988181",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Li J, Pei H, Zhu B et al. (2011). \"Self-assembled multivalent DNA nanostructures for noninvasive intracellular delivery of immunostimulatory CpG oligonucleotides.\" ACS Nano 5(11):8783–8789 — Landmark: first CpG delivery via DNA tetrahedron",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
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      "corrections": [],
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    {
      "ref": "NPL-59",
      "recordId": "hsi-e4fe63d45bf8b9",
      "sourceType": "Journal publication",
      "title": "Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.",
      "authors": "Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG.",
      "year": 2012,
      "journal": "Nature nanotechnology",
      "doi": "10.1038/nnano.2012.73",
      "pmid": "22659608",
      "pmcid": "PMC3898745",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Lee H, Lytton-Jean AKR, Chen Y et al. (2012). \"Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.\" Nature Nanotechnology 7(6):389–393 — Landmark: siRNA delivery via DNA tetrahedron extending in vivo half-life",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
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      "corrections": [],
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    },
    {
      "ref": "NPL-60",
      "recordId": "hsi-0f08e7dadf9e0b",
      "sourceType": "Review",
      "title": "Revolutionizing cancer therapy using tetrahedral DNA nanostructures as intelligent drug delivery systems.",
      "authors": "Sharma A, Vaswani P, Bhatia D.",
      "year": 2024,
      "journal": "Nanoscale advances",
      "doi": "10.1039/d4na00145a",
      "pmid": "39050960",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Zhang T et al. (2024). \"Revolutionizing cancer therapy using tetrahedral DNA nanostructures as intelligent drug delivery systems.\" Nanoscale Advances (RSC Publishing) (PMC 11265600)",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
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    },
    {
      "ref": "NPL-61",
      "recordId": "pmid-28891335",
      "sourceType": "Review",
      "title": "Development of DNA tetrahedron-based drug delivery system.",
      "authors": "Hu Y, Chen Z, Zhang H, Li M, Hou Z, Luo X, Xue X.",
      "year": 2017,
      "journal": "Drug delivery",
      "doi": "10.1080/10717544.2017.1373166",
      "pmid": "28891335",
      "pmcid": "PMC8241089",
      "patentNumber": null,
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      "originalCitation": "Hu Y, Chen Z, Zhang H et al. (2017). \"Development of DNA tetrahedron-based drug delivery systems.\" Drug Delivery 24(1):1295–1301 (PMC 8241089)",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
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    },
    {
      "ref": "NPL-62",
      "recordId": "hsi-73a17e50a48e07",
      "sourceType": "Review",
      "title": "DNA Nanotechnology for Cancer Therapy.",
      "authors": "Kumar V, Palazzolo S, Bayda S, Corona G, Toffoli G, Rizzolio F.",
      "year": 2016,
      "journal": "Theranostics",
      "doi": "10.7150/thno.14203",
      "pmid": "27022418",
      "pmcid": "PMC4805665",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Angell C, Xie S, Zhang L, Chen Y (2016). \"DNA Nanotechnology for Cancer Therapy.\" Journal of Biomedical Nanotechnology 12(6):1101–1116 (PMC 4805665)",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
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    {
      "ref": "NPL-63",
      "recordId": "hsi-7388517063a7af",
      "sourceType": "Review",
      "title": "Applications of tetrahedral DNA nanostructures in wound repair and tissue regeneration.",
      "authors": "Dou Y, Cui W, Yang X, Lin Y, Ma X, Cai X.",
      "year": 2022,
      "journal": "Burns & trauma",
      "doi": "10.1093/burnst/tkac006",
      "pmid": "35280457",
      "pmcid": "PMC8912983",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Zhang M, Zhang X, Tian T et al. (2022). \"Applications of tetrahedral DNA nanostructures in wound repair and tissue regeneration.\" Military Medical Research 9:12 (PMC 8912983)",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
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    },
    {
      "ref": "NPL-64",
      "recordId": "hsi-ab0d1892ea7227",
      "sourceType": "Review",
      "title": "Advances in regenerative medicine applications of tetrahedral framework nucleic acid-based nanomaterials: an expert consensus recommendation.",
      "authors": "Lin Y, Li Q, Wang L, Guo Q, Liu S, Zhu S, Sun Y, Fan Y, Sun Y, Li H, Tian X, Luo D, Shi S.",
      "year": 2022,
      "journal": "International journal of oral science",
      "doi": "10.1038/s41368-022-00199-9",
      "pmid": "36316311",
      "pmcid": "PMC9622686",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Liu Y, Sun Y, Li S et al. (2022). \"Advances in regenerative medicine applications of tetrahedral framework nucleic acid-based nanomaterials: an expert consensus recommendation.\" International Journal of Oral Science (Nature) 14:51",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
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      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/36316311/",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-65",
      "recordId": "hsi-83b2680d02c658",
      "sourceType": "Review",
      "title": "DNA Nanostructure as an Efficient Drug Delivery Platform for Immunotherapy.",
      "authors": "Chi Q, Yang Z, Xu K, Xu K, Wang C, Liang H.",
      "year": 2019,
      "journal": "Frontiers in pharmacology",
      "doi": "10.3389/fphar.2019.01585",
      "pmid": "32063844",
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      "originalCitation": "Liu J, Song L, Liu S et al. (2019). \"DNA Nanostructure as an Efficient Drug Delivery Platform for Immunotherapy.\" Frontiers in Pharmacology 10:1585",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
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      "corrections": [
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    },
    {
      "ref": "NPL-66",
      "recordId": "hsi-ab41c0abb24e53",
      "sourceType": "Journal publication",
      "title": "DNA origami as a carrier for circumvention of drug resistance.",
      "authors": "Jiang Q, Song C, Nangreave J, Liu X, Lin L, Qiu D, Wang ZG, Zou G, Liang X, Yan H, Ding B.",
      "year": 2012,
      "journal": "Journal of the American Chemical Society",
      "doi": "10.1021/ja304263n",
      "pmid": "22803823",
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      "originalCitation": "Jiang Q, Song C, Nangreave J et al. (2012). \"DNA Origami as a Carrier for Circumvention of Drug Resistance.\" Journal of the American Chemical Society 134(32):13396–13403 — Landmark: DNA nanostructures overcoming drug resistance in cancer",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
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    {
      "ref": "NPL-67",
      "recordId": "hsi-2bdd395b380845",
      "sourceType": "Journal publication",
      "title": "Systematic Study in Mammalian Cells Showing No Adverse Response to Tetrahedral DNA Nanostructure.",
      "authors": "Xia K, Kong H, Cui Y, Ren N, Li Q, Ma J, Cui R, Zhang Y, Shi J, Li Q, Lv M, Sun Y, Wang L, Li J, Zhu Y.",
      "year": 2018,
      "journal": "ACS applied materials & interfaces",
      "doi": "10.1021/acsami.8b02626",
      "pmid": "29668248",
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      "patentNumber": null,
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      "originalCitation": "Xia K, Kong H, Cui Y et al. (2022). \"Systematic study in mammalian cells showing no adverse response to tetrahedral DNA nanostructure.\" ACS Applied Materials & Interfaces 10(18):15442–15452 (PMC 6032219) — Biocompatibility validation",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
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      "ref": "NPL-68",
      "recordId": "hsi-f195eb8e628a71",
      "sourceType": "Journal publication",
      "title": "Mitochondria-targeted tetrahedral DNA nanostructures for doxorubicin delivery and enhancement of apoptosis.",
      "authors": "Yan J, Chen J, Zhang N, Yang Y, Zhu W, Li L, He B.",
      "year": 2020,
      "journal": "Journal of materials chemistry. B",
      "doi": "10.1039/c9tb02266j",
      "pmid": "31840727",
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      "originalCitation": "Yan J, Chen J, Zhang N et al. (2020). \"Mitochondria-targeted tetrahedral DNA nanostructures for doxorubicin delivery and enhancement of apoptosis.\" Journal of Materials Chemistry B (RSC Publishing)",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
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    {
      "ref": "NPL-69",
      "recordId": "hsi-60b2c2a14403dd",
      "sourceType": "Journal publication",
      "title": "Targeted Imaging of Brain Tumors with a Framework Nucleic Acid Probe.",
      "authors": "Tian T, Li J, Xie C, Sun Y, Lei H, Liu X, Xia J, Shi J, Wang L, Lu W, Fan C.",
      "year": 2018,
      "journal": "ACS applied materials & interfaces",
      "doi": "10.1021/acsami.7b17927",
      "pmid": "29299920",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Tian T, Li J, Xie C et al. (2023). \"Targeted imaging of brain tumors with a framework nucleic acid probe.\" ACS Applied Materials & Interfaces 15(7):9223–9232 — TDN for neurological disease imaging",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-70",
      "recordId": "hsi-8d0c61cbbe9b8f",
      "sourceType": "Journal publication",
      "title": "Aptamer-Modified Tetrahedral DNA Nanostructure for Tumor-Targeted Drug Delivery.",
      "authors": "Li Q, Zhao D, Shao X, Lin S, Xie X, Liu M, Ma W, Shi S, Lin Y.",
      "year": 2017,
      "journal": "ACS applied materials & interfaces",
      "doi": "10.1021/acsami.7b13328",
      "pmid": "28991436",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Li Q, Zhao D, Shao X et al. (2017). \"Aptamer-modified tetrahedral DNA nanostructure for tumor-targeted drug delivery.\" ACS Applied Materials & Interfaces 9(42):36695–36701 — Aptamer-functionalised TDN for targeted oncology",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-71",
      "recordId": "hsi-bf70680de4d4e4",
      "sourceType": "Bibliographic source",
      "title": "Biomimetic nanoerythrosome-coated aptamer–DNA tetrahedron/maytansine conjugates: pH-responsive drug release, targeted delivery and synergistic treatment of cancer",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
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      "originalAssignee": null,
      "originalCitation": "Ma W, Yang Y, Zhu J et al. (2022). \"Biomimetic nanoerythrosome-coated aptamer–DNA tetrahedron/maytansine conjugates: pH-responsive drug release, targeted delivery and synergistic treatment of cancer.\" Nature Communications — DNA tetrahedron conjugate for synergistic cancer therapy",
      "originalSection": "Platonic Geometries / DNA Tetrahedrons",
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    {
      "ref": "NPL-72",
      "recordId": "hsi-10ecf2c046f745",
      "sourceType": "Journal publication",
      "title": "X-ray structures and mechanism of the human serotonin transporter.",
      "authors": "Coleman JA, Green EM, Gouaux E.",
      "year": 2016,
      "journal": "Nature",
      "doi": "10.1038/nature17629",
      "pmid": "27049939",
      "pmcid": "PMC4898786",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Coleman JA, Green EM, Gouaux E (2016). \"X-ray structures and mechanism of the human serotonin transporter.\" Nature 532(7599):334–339",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [],
      "topicId": null,
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    },
    {
      "ref": "NPL-73",
      "recordId": "hsi-946216a176e063",
      "sourceType": "Journal publication",
      "title": "G Protein Activation by Serotonin Type 4 Receptor Dimers",
      "authors": "Lucie P. Pellissier; Gaël Barthet; Florence Gaven; Elisabeth Cassier; Eric Trinquet; Jean-Philippe Pin; Philippe Marin; Aline Dumuis; Joël Bockaert; Jean-Louis Banères; Sylvie Claeysen",
      "year": 2011,
      "journal": "Journal of Biological Chemistry",
      "doi": "10.1074/jbc.m110.201939",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Pellissier LP et al. (2011). \"G protein activation by serotonin type 4 receptor dimers.\" Journal of Biological Chemistry 286(12):9985–9997",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.1074/jbc.m110.201939",
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    {
      "ref": "NPL-74",
      "recordId": "portal-75ae9eff6740",
      "sourceType": "Journal publication",
      "title": "Effect of 528 Hz Music on the Endocrine System and Autonomic Nervous System",
      "authors": "Kaho Akimoto; Ailing Hu; Takuji Yamaguchi; Hiroyuki Kobayashi",
      "year": 2018,
      "journal": "Health",
      "doi": "10.4236/health.2018.109088",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Akimoto K, Hu A, Yamaguchi T, Kobayashi H (2018). \"Effect of 528 Hz Music on the Endocrine System and Autonomic Nervous System.\" Health (SCIRP) 10:1159–1170",
      "originalSection": "528 Hz Sound Frequency and Oxytocin Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.4236/health.2018.109088",
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      "corrections": [],
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    },
    {
      "ref": "NPL-75",
      "recordId": "hsi-aab85699a77a3d",
      "sourceType": "Journal publication",
      "title": "Oxytocin inhibits ethanol consumption and ethanol-induced dopamine release in the nucleus accumbens.",
      "authors": "Peters ST, Bowen MT, Bohrer K, McGregor IS, Neumann ID.",
      "year": 2017,
      "journal": "Addiction biology",
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      "pmid": "26810371",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Peters ST, Bowen MT, Bohrer K, McGregor IS, Neumann ID (2017). \"Oxytocin inhibits ethanol consumption and ethanol-induced dopamine release in the nucleus accumbens.\" Addiction Biology 22(3):702–711",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/26810371/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Oxytocin+inhibits+ethanol+consumption+and+ethanol-induced+dopamine+release+in+the+nucleus+accumbens%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-76",
      "recordId": "hsi-77718f06669535",
      "sourceType": "Journal publication",
      "title": "Oxytocin Acts in Nucleus Accumbens to Attenuate Methamphetamine Seeking and Demand.",
      "authors": "Cox BM, Bentzley BS, Regen-Tuero H, See RE, Reichel CM, Aston-Jones G.",
      "year": 2017,
      "journal": "Biological psychiatry",
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      "pmid": "28110822",
      "pmcid": "PMC5432412",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Cox BM, Bentzley BS, Regen-Tuero H, See RE, Reichel CM, Aston-Jones G (2017). \"Oxytocin acts in nucleus accumbens to attenuate methamphetamine seeking and demand.\" Biological Psychiatry 81(11):949–958",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/28110822/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Oxytocin+acts+in+nucleus+accumbens+to+attenuate+methamphetamine+seeking+and+demand%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
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    },
    {
      "ref": "NPL-77",
      "recordId": "hsi-4af2057b096b94",
      "sourceType": "Journal publication",
      "title": "Intranasal oxytocin blocks alcohol withdrawal in human subjects.",
      "authors": "Pedersen CA, Smedley KL, Leserman J, Jarskog LF, Rau SW, Kampov-Polevoi A, Casey RL, Fender T, Garbutt JC.",
      "year": 2013,
      "journal": "Alcoholism, clinical and experimental research",
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      "pmid": "23025690",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Pedersen CA, Smedley KL, Leserman J et al. (2013). \"Intranasal oxytocin blocks alcohol withdrawal in human subjects.\" Alcoholism: Clinical and Experimental Research 37(3):484–489",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/23025690/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Intranasal+oxytocin+blocks+alcohol+withdrawal+in+human+subjects%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-78",
      "recordId": "hsi-47902eba688213",
      "sourceType": "Journal publication",
      "title": "Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans.",
      "authors": "Hansson AC, Koopmann A, Uhrig S, Bühler S, Domi E, Kiessling E, Ciccocioppo R, Froemke RC, Grinevich V, Kiefer F, Sommer WH, Vollstädt-Klein S, Spanagel R.",
      "year": 2018,
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      "doi": "10.1038/npp.2017.257",
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      "pmcid": "PMC5916348",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Hansson AC et al. (2018). \"Oxytocin reduces alcohol cue-reactivity in alcohol-dependent rats and humans.\" Neuropsychopharmacology 43(6):1235–1246",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/29090683/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Oxytocin+reduces+alcohol+cue-reactivity+in+alcohol-dependent+rats+and+humans%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-79",
      "recordId": "hsi-8a8678573fb17e",
      "sourceType": "Bibliographic source",
      "title": "Intranasal oxytocin attenuates cue-elicited reward-related brain activation in cocaine users",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Joseph JE et al. (2019). \"Intranasal oxytocin attenuates cue-elicited reward-related brain activation in cocaine users.\" NeuroImage: Clinical 23:101839",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "unresolved",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
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    },
    {
      "ref": "NPL-80",
      "recordId": "hsi-07cc188cceb30b",
      "sourceType": "Bibliographic source",
      "title": "Effect of intranasal oxytocin on heroin craving and withdrawal",
      "authors": null,
      "year": null,
      "journal": null,
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      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Moeini M et al. (2019). \"Effect of intranasal oxytocin on heroin craving and withdrawal.\" Journal of Clinical Psychopharmacology 39(3):215–221",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "unresolved",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
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      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-81",
      "recordId": "hsi-95de488967bdae",
      "sourceType": "Journal publication",
      "title": "Switching brain serotonin with oxytocin.",
      "authors": "Mottolese R, Redouté J, Costes N, Le Bars D, Sirigu A.",
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      "journal": "Proceedings of the National Academy of Sciences of the United States of America",
      "doi": "10.1073/pnas.1319810111",
      "pmid": "24912179",
      "pmcid": "PMC4060712",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Mottolese R, Redouté J, Costes N, Le Bars D, Sirigu A (2014). \"Switching brain serotonin with oxytocin.\" Proceedings of the National Academy of Sciences 111(23):8637–8642",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/24912179/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Switching+brain+serotonin+with+oxytocin%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-82",
      "recordId": "hsi-fa5125a3521b41",
      "sourceType": "Journal publication",
      "title": "Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice.",
      "authors": "Yoshida M, Takayanagi Y, Inoue K, Kimura T, Young LJ, Onaka T, Nishimori K.",
      "year": 2009,
      "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Yoshida M et al. (2009). \"Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice.\" Journal of Neuroscience 29(7):2259–2271",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/19228979/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Evidence+that+oxytocin+exerts+anxiolytic+effects+via+oxytocin+receptor+expressed+in+serotonergic+neurons+in+mice%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-83",
      "recordId": "pmid-24025838",
      "sourceType": "Journal publication",
      "title": "Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin.",
      "authors": "Dölen G, Darvishzadeh A, Huang KW, Malenka RC.",
      "year": 2013,
      "journal": "Nature",
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      "pmid": "24025838",
      "pmcid": "PMC4091761",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Dölen G, Darvishzadeh A, Huang KW, Malenka RC (2013). \"Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin.\" Nature 501(7466):179–184",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.nature.com/articles/nature12518",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Social+reward+requires+coordinated+activity+of+nucleus+accumbens+oxytocin+and+serotonin%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-84",
      "recordId": "hsi-6e4cd0919dfce6",
      "sourceType": "Bibliographic source",
      "title": "Fuller RB (1975). Synergetics: Explorations in the Geometry of Thinking. New York: Macmillan. §§460.00–465.00 (Jitterbug Transformation)",
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      "year": null,
      "journal": null,
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      "pmid": null,
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Fuller RB (1975). Synergetics: Explorations in the Geometry of Thinking. New York: Macmillan. §§460.00–465.00 (Jitterbug Transformation)",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
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    },
    {
      "ref": "NPL-85",
      "recordId": "hsi-8f5609e6da289b",
      "sourceType": "Bibliographic source",
      "title": "Ball WWR, Coxeter HSM (1987). Mathematical Recreations and Essays. 13th ed. Dover. pp. 135–144",
      "authors": null,
      "year": null,
      "journal": null,
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      "originalAssignee": null,
      "originalCitation": "Ball WWR, Coxeter HSM (1987). Mathematical Recreations and Essays. 13th ed. Dover. pp. 135–144",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
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    {
      "ref": "NPL-86",
      "recordId": "hsi-7d3097f47eb89f",
      "sourceType": "Bibliographic source",
      "title": "Coxeter HSM, Du Val P, Flather HT, Petrie JF (1938). The Fifty-Nine Icosahedra. University of Toronto Studies, Mathematical Series 6",
      "authors": null,
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    {
      "ref": "NPL-87",
      "recordId": "hsi-0c64f140769534",
      "sourceType": "Bibliographic source",
      "title": "Wenninger MJ (1971). Polyhedron Models. Cambridge University Press. pp. 37",
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      "originalCitation": "Wenninger MJ (1971). Polyhedron Models. Cambridge University Press. pp. 37",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "documentary-source",
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      "corrections": [],
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      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-88",
      "recordId": "hsi-39fab96b7c60e8",
      "sourceType": "Bibliographic source",
      "title": "Cromwell PR (1997). Polyhedra. Cambridge University Press. pp. 124, 152",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
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      "originalCitation": "Cromwell PR (1997). Polyhedra. Cambridge University Press. pp. 124, 152",
      "originalSection": "Gene-Correlated Platonic Solid Inference Vectors",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    },
    {
      "ref": "NPL-89",
      "recordId": "hsi-26e06f24f0b804",
      "sourceType": "Journal publication",
      "title": "Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine D1-like receptors in mice.",
      "authors": "Shin EJ, Jeong JH, Kim HJ, Jang CG, Yamada K, Nabeshima T, Kim HC.",
      "year": 2007,
      "journal": "Journal of pharmacological sciences",
      "doi": "10.1254/jphs.sc0070348",
      "pmid": "18094524",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Shin HJ et al. (2007). \"Exposure to Extremely Low Frequency Magnetic Fields Enhances Locomotor Activity via Activation of Dopamine D1-Like Receptors in Mice.\" Journal of Pharmacological Sciences",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [],
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    {
      "ref": "NPL-90",
      "recordId": "hsi-30665e57818748",
      "sourceType": "Bibliographic source",
      "title": "Increasing striatal dopamine release through repeated bouts of theta burst TMS of the left DLPFC",
      "authors": null,
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      "journal": null,
      "doi": null,
      "pmid": null,
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      "originalCitation": "Shaikh S et al. (2024). \"Increasing striatal dopamine release through repeated bouts of theta burst TMS of the left DLPFC.\" Frontiers in Neuroscience",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "unresolved",
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      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-91",
      "recordId": "hsi-5251fd98c28e8b",
      "sourceType": "Journal publication",
      "title": "Theta burst stimulation-induced inhibition of dorsolateral prefrontal cortex reveals hemispheric asymmetry in striatal dopamine release during a set-shifting task: a TMS-[(11)C]raclopride PET study.",
      "authors": "Ko JH, Monchi O, Ptito A, Bloomfield P, Houle S, Strafella AP.",
      "year": 2008,
      "journal": "The European journal of neuroscience",
      "doi": "10.1111/j.1460-9568.2008.06501.x",
      "pmid": "19046396",
      "pmcid": "PMC2967524",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Ko JH et al. (2008). \"Theta burst stimulation-induced inhibition of dorsolateral prefrontal cortex reveals hemispheric asymmetry in striatal dopamine release during a set-shifting task.\" European Journal of Neuroscience",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/19046396/",
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      "corrections": [
        "Published title reconciled with the metadata record."
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      "topicId": null,
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    },
    {
      "ref": "NPL-92",
      "recordId": "hsi-4efe761244a9d1",
      "sourceType": "Journal publication",
      "title": "D2 receptor block abolishes θ burst stimulation-induced neuroplasticity in the human motor cortex.",
      "authors": "Monte-Silva K, Ruge D, Teo JT, Paulus W, Rothwell JC, Nitsche MA.",
      "year": 2011,
      "journal": "Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology",
      "doi": "10.1038/npp.2011.100",
      "pmid": "21697824",
      "pmcid": "PMC3158306",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Monte-Silva K et al. (2011). \"D2 Receptor Block Abolishes Theta Burst Stimulation-Induced Neuroplasticity in the Human Motor Cortex.\" Neuropsychopharmacology (PMC3158306)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/21697824/",
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      "corrections": [
        "Published title reconciled with the metadata record."
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    },
    {
      "ref": "NPL-93",
      "recordId": "hsi-be932d8730b595",
      "sourceType": "Journal publication",
      "title": "Continuous but not intermittent theta burst stimulation decreases striatal dopamine release and cortical excitability.",
      "authors": "Aceves-Serrano L, Neva JL, Munro J, Parent M, Boyd LA, Doudet DJ.",
      "year": 2022,
      "journal": "Experimental neurology",
      "doi": "10.1016/j.expneurol.2022.114106",
      "pmid": "35526596",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Aceves-Serrano L, Neva JL, Munro J, Parent M, Boyd LA, Doudet DJ (2022). \"Continuous but not intermittent theta burst stimulation decreases striatal dopamine release and cortical excitability.\" Experimental Neurology 354:114106 (PMID 35526596) — cTBS over left M1 acutely decreased dopamine release bilaterally in putamen; iTBS did not affect dopamine release. [Note: original citation attributed to \"Bhatt DK et al.\" — corrected to Aceves-Serrano L et al. as verified authors]",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
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    },
    {
      "ref": "NPL-94a",
      "recordId": "hsi-30d689c8edc32d",
      "sourceType": "Journal publication",
      "title": "Repetitive transcranial magnetic stimulation of the human prefrontal cortex induces dopamine release in the caudate nucleus.",
      "authors": "Strafella AP, Paus T, Barrett J, Dagher A.",
      "year": 2001,
      "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
      "doi": "10.1523/jneurosci.21-15-j0003.2001",
      "pmid": "11459878",
      "pmcid": "PMC6762641",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Strafella AP, Paus T, Barrett J, Dagher A (2001). \"Repetitive transcranial magnetic stimulation of the human prefrontal cortex induces dopamine release in the caudate nucleus.\" Journal of Neuroscience 21(15):RC157 (PMID 11459878)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
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      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/11459878/",
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      "corrections": [],
      "topicId": null,
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    },
    {
      "ref": "NPL-94b",
      "recordId": "hsi-15872e1b8b4ebc",
      "sourceType": "Journal publication",
      "title": "Striatal dopamine release induced by repetitive transcranial magnetic stimulation of the human motor cortex.",
      "authors": "Strafella AP, Paus T, Fraraccio M, Dagher A.",
      "year": 2003,
      "journal": "Brain : a journal of neurology",
      "doi": "10.1093/brain/awg268",
      "pmid": "12937078",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Strafella AP, Paus T, Barrett J, Dagher A (2003). \"Striatal dopamine release induced by repetitive transcranial magnetic stimulation of the human motor cortex.\" Brain 126(12):2609–2615 (PMID 12937078)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/12937078/",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-95",
      "recordId": "hsi-4bc623819a8a2f",
      "sourceType": "Bibliographic source",
      "title": "Extremely low-frequency electromagnetic field exposure during morphine treatment on dopamine D2 receptor expression",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Wang C et al. (2008). \"Extremely low-frequency electromagnetic field exposure during morphine treatment on dopamine D2 receptor expression.\" Neuroscience Letters",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "unresolved",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-96a",
      "recordId": "hsi-608c987e1bbe8a",
      "sourceType": "Review",
      "title": "Magnetic fields in the therapy of parkinsonism.",
      "authors": "Sandyk R.",
      "year": 1992,
      "journal": "The International journal of neuroscience",
      "doi": null,
      "pmid": "1305620",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Sandyk R (1992). \"Magnetic fields in the therapy of parkinsonism.\" International Journal of Neuroscience 66(3–4):209–235 (PMID 1305620) — Foundational report: picoTesla ELF magnetic fields produced sustained improvement in >20 Parkinson's patients",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/1305620/",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-96b",
      "recordId": "hsi-dbaacd77b57047",
      "sourceType": "Journal publication",
      "title": "Treatment of Parkinson's disease with magnetic fields reduces the requirement for antiparkinsonian medications.",
      "authors": "Sandyk R.",
      "year": 1994,
      "journal": "The International journal of neuroscience",
      "doi": "10.3109/00207459408987239",
      "pmid": "7928105",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Sandyk R (1994). \"Treatment of Parkinson's disease with magnetic fields reduces the requirement for antiparkinsonian medications.\" International Journal of Neuroscience (PMID 7928105) — picoTesla MF reduced medication requirement",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/7928105/",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-96c",
      "recordId": "hsi-65629c874781f2",
      "sourceType": "Journal publication",
      "title": "The effects of external picotesla range magnetic fields on the EEG in Parkinson's disease: a follow up study.",
      "authors": "Sandyk R.",
      "year": 1994,
      "journal": "The International journal of neuroscience",
      "doi": "10.3109/00207459408986004",
      "pmid": "7960478",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Sandyk R (1994). \"The effects of external picotesla range magnetic fields on the EEG in Parkinson's disease: a follow up study.\" International Journal of Neuroscience 76(3–4):227–229 (PMID 7960478)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/7960478/",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-97",
      "recordId": "src-d1eaa478462e",
      "sourceType": "Journal publication",
      "title": "Long-Term Study of Heart Rate Variability Responses to Changes in the Solar and Geomagnetic Environment.",
      "authors": "Alabdulgader A, McCraty R, Atkinson M, Dobyns Y, Vainoras A, Ragulskis M, Stolc V.",
      "year": 2018,
      "journal": "Scientific reports",
      "doi": "10.1038/s41598-018-20932-x",
      "pmid": "29422633",
      "pmcid": "PMC5805718",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "McCraty R et al. (2017). \"Long-Term Study of Heart Rate Variability Responses to Changes in the Solar and Geomagnetic Environment.\" Scientific Reports (Nature) 7:16338",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.heartmath.org/research/research-library/coherence/long-term-study-of-hrv-responses-to-changes-in-solar-geomagnetic-enviroment",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Long-Term+Study+of+Heart+Rate+Variability+Responses+to+Changes+in+the+Solar+and+Geomagnetic+Environment%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-98",
      "recordId": "pmid-28703754",
      "sourceType": "Journal publication",
      "title": "Synchronization of Human Autonomic Nervous System Rhythms with Geomagnetic Activity in Human Subjects.",
      "authors": "McCraty R, Atkinson M, Stolc V, Alabdulgader AA, Vainoras A, Ragulskis M.",
      "year": 2017,
      "journal": "International journal of environmental research and public health",
      "doi": "10.3390/ijerph14070770",
      "pmid": "28703754",
      "pmcid": "PMC5551208",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Alabdulgader AA et al. (2018). \"Synchronization of Human Autonomic Nervous System Rhythms with Geomagnetic Activity in Human Subjects.\" International Journal of Environmental Research and Public Health (PMC5551208)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/28703754/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC5551208&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-99",
      "recordId": "hsi-9754d6a5bca560",
      "sourceType": "Journal publication",
      "title": "Schumann Resonances and the Human Body: Questions About Interactions, Problems and Prospects",
      "authors": "Ganna Nevoit; Mantas Landauskas; Rollin McCarty; Inga Arune Bumblyte; Maksim Potyazhenko; Giedre Taletaviciene; Gediminas Jarusevicius; Alfonsas Vainoras",
      "year": 2025,
      "journal": "Applied Sciences",
      "doi": "10.3390/app15010449",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Sdraulig S et al. (2023). \"Schumann Resonances and the Human Body: Questions About Interactions, Problems and Prospects.\" Applied Sciences (MDPI) 15(1):449",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.3390/app15010449",
      "metadataURL": "https://api.crossref.org/works?query.title=Schumann+Resonances+and+the+Human+Body%3A+Questions+About+Interactions%2C+Problems+and+Prospects&rows=3",
      "corrections": [
        "Author attribution differs from the public metadata; canonical authors are shown in source details."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-100a",
      "recordId": "hsi-de25bca76daa01",
      "sourceType": "Journal publication",
      "title": "Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences.",
      "authors": "Montagnier L, Aïssa J, Ferris S, Montagnier JL, Lavallée C.",
      "year": 2009,
      "journal": "Interdisciplinary sciences, computational life sciences",
      "doi": "10.1007/s12539-009-0036-7",
      "pmid": "20640822",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Montagnier L, Aissa J, Ferris S, Montagnier JL, Lavallée C (2009). \"Electromagnetic Signals Are Produced by Aqueous Nanostructures Derived from Bacterial DNA Sequences.\" Interdisciplinary Sciences: Computational Life Sciences 1(2):81–90 (PMID 20640822)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/20640822/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID%3A20640822+AND+SRC%3AMED&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-100b",
      "recordId": "src-5aaad2520e3b",
      "sourceType": "Conference publication",
      "title": "DNA waves and water",
      "authors": "L Montagnier; J Aissa; E Del Giudice; C Lavallee; A Tedeschi; G Vitiello",
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      "sourceType": "Review",
      "title": "Transduction of DNA information through water and electromagnetic waves.",
      "authors": "Montagnier L, Del Giudice E, Aïssa J, Lavallee C, Motschwiller S, Capolupo A, Polcari A, Romano P, Tedeschi A, Vitiello G.",
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      "originalCitation": "Montagnier L, Del Giudice E, Aissa J et al. (2015). \"Transduction of DNA information through water and electromagnetic waves.\" Electromagnetic Biology and Medicine 34(2):106–112 (PMID 26098521) — 7 Hz electromagnetic stimulation required for DNA transduction; removal of Schumann resonance background abolished effect.",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
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      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "sourceType": "Journal publication",
      "title": "Effects of extremely low-frequency electromagnetic fields on B16F10 cancer cells.",
      "authors": "Tang JY, Yeh TW, Huang YT, Wang MH, Jang LS.",
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      "sourceType": "Journal publication",
      "title": "Inhibition of B16F10 Cancer Cell Growth by Exposure to the Square Wave with 7.83+/-0.3Hz Involves L- and T-Type Calcium Channels.",
      "authors": "Wang MH, Jian MW, Tai YH, Jang LS, Chen CH.",
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      "originalCitation": "Tang JY et al. (2020). Electromagnetic Biology and Medicine (PMID 33111597) — 7.83 Hz ELF: 26.4% melanoma cell growth inhibition via calcium channel modulation",
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      "title": "Kim JH et al. (2015). ELF-MF altered turnover and receptor reactivity of serotonergic and dopaminergic systems. Brain Sciences (MDPI)",
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      "recordId": "hsi-77fdc107df5fe0",
      "sourceType": "Journal publication",
      "title": "Extremely low frequency magnetic field modulates the level of neurotransmitters.",
      "authors": "Chung YH, Lee YJ, Lee HS, Chung SJ, Lim CH, Oh KW, Sohn UD, Park ES, Jeong JH.",
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      "journal": "The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology",
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      "originalCitation": "Cichon N et al. (2015). ELF-MF modulated major neurotransmitter levels in rat brain including elevated dopamine in thalamus. Bioelectromagnetics (PMC4297757)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
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    {
      "ref": "NPL-104",
      "recordId": "hsi-228d0ab78ee822",
      "sourceType": "Review",
      "title": "Exploring the influence of Schumann resonance and electromagnetic fields on bioelectricity and human health.",
      "authors": "Nelson I.",
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      "originalCitation": "Gazdag E (2025). \"Exploring the influence of Schumann resonance and electromagnetic fields on bioelectricity and human health.\" Electromagnetic Biology and Medicine",
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    {
      "ref": "NPL-105",
      "recordId": "pmid-16275477",
      "sourceType": "Journal publication",
      "title": "Does Schumann resonance affect our blood pressure?",
      "authors": "Mitsutake G, Otsuka K, Hayakawa M, Sekiguchi M, Cornélissen G, Halberg F.",
      "year": 2005,
      "journal": "Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie",
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      "originalCitation": "Gmitrov J, Ohkubo C (2002). \"Does Schumann resonance affect our blood pressure?\" Biomedicine & Pharmacotherapy (PMC2656447)",
      "originalSection": "Schumann Resonance, ELF, and Dopaminergic Modulation",
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    {
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      "recordId": "src-76124b78a2d9",
      "sourceType": "Journal publication",
      "title": "The Effects of 528 Hz Sound Wave to Reduce Cell Death in Human Astrocyte Primary Cell Culture Treated with Ethanol",
      "authors": "Tohid Babayi; Gholam Hossein Riazi",
      "year": 2017,
      "journal": "Journal of Addiction Research & Therapy",
      "doi": "10.4172/2155-6105.1000335",
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      "originalCitation": "Babayi G, Riazi GH (2017). \"The Effects of 528 Hz Sound Wave to Reduce Cell Death in Human Astrocyte Primary Cell Culture Treated with Ethanol.\" Journal of Addiction Research & Therapy",
      "originalSection": "528 Hz Sound Frequency and Oxytocin Modulation",
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    {
      "ref": "NPL-107",
      "recordId": "pmid-30414050",
      "sourceType": "Journal publication",
      "title": "Influence of various intensities of 528 Hz sound-wave in production of testosterone in rat's brain and analysis of behavioral changes.",
      "authors": "Babayi Daylari T, Riazi GH, Pooyan S, Fathi E, Hedayati Katouli F.",
      "year": 2019,
      "journal": "Genes & genomics",
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      "pmid": "30414050",
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      "originalCitation": "Babayi Daylari M et al. (2019). \"Influence of various intensities of 528 Hz sound-wave in production of testosterone in rat's brain and analysis of behavioral changes.\" Genes & Genomics (Springer)",
      "originalSection": "528 Hz Sound Frequency and Oxytocin Modulation",
      "metadataStatus": "metadata-matched",
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    {
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      "recordId": "hsi-c2e2e55e945231",
      "sourceType": "Journal publication",
      "title": "Effect of OM Chanting of 528Hz Frequency on Heart Rate Variability, Psychological Wellbeing, and Quality of Sleep in Patients of Hypertension: A Randomised Controlled Trial.",
      "authors": "Bhoot A, Chowdhury AB, Shah H, Vaishnav B.",
      "year": 2025,
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      "pmid": "41395351",
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      "patentNumber": null,
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      "originalCitation": "OM Chanting 528 Hz RCT (2024). \"Effect of OM Chanting of 528Hz Frequency on Heart Rate Variability, Psychological Wellbeing, and Quality of Sleep in Patients of Hypertension.\" PMC (PMC12700779)",
      "originalSection": "528 Hz Sound Frequency and Oxytocin Modulation",
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    {
      "ref": "NPL-109",
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      "sourceType": "Bibliographic source",
      "title": "Feneberg AC et al. (2020) / PMC Music-as-Stress-Management Review (2022). 528 Hz more pronounced stress-reducing effect than 440 Hz; lowers cortisol, increases oxytocin. Frontiers in Psychiatry; PMC (PMC9480195)",
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      "originalSection": "528 Hz Sound Frequency and Oxytocin Modulation",
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    {
      "ref": "NPL-110",
      "recordId": "hsi-678a9434e390e7",
      "sourceType": "Journal publication",
      "title": "Certain frequency music has attracted attention for possible effective healing",
      "authors": "Hiroshi BANDO; Akiyo Yoshioka; Masahiro Bando; Yu Nishikiori",
      "year": 2023,
      "journal": "International Journal of Complementary and Alternative Medicine",
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      "pmid": null,
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Nozaki M (2023). \"Certain frequency music has attracted attention for possible effective healing.\" 528 Hz reduced cortisol/chromogranin A, increased oxytocin. International Journal of Complementary & Alternative Medicine",
      "originalSection": "528 Hz Sound Frequency and Oxytocin Modulation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-112",
      "recordId": "hsi-f7aa09edd12cad",
      "sourceType": "Journal publication",
      "title": "Neural correlates of the DMT experience assessed with multivariate EEG.",
      "authors": "Timmermann C, Roseman L, Schartner M, Milliere R, Williams LTJ, Erritzoe D, Muthukumaraswamy S, Ashton M, Bendrioua A, Kaur O, Turton S, Nour MM, Day CM, Leech R, Nutt DJ, Carhart-Harris RL.",
      "year": 2019,
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Timmermann C et al. (2019). \"Neural correlates of the DMT experience assessed with multivariate EEG.\" IV DMT: increased gamma oscillations, 5-HT2A mediated. Scientific Reports (Nature)",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-113",
      "recordId": "hsi-c6f6e59d6a927f",
      "sourceType": "Journal publication",
      "title": "Human brain effects of DMT assessed via EEG-fMRI.",
      "authors": "Timmermann C, Roseman L, Haridas S, Rosas FE, Luan L, Kettner H, Martell J, Erritzoe D, Tagliazucchi E, Pallavicini C, Girn M, Alamia A, Leech R, Nutt DJ, Carhart-Harris RL.",
      "year": 2023,
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      "patentNumber": null,
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      "originalCitation": "Timmermann C et al. (2023). \"Human brain effects of DMT assessed via EEG-fMRI.\" DMT gamma oscillations correlated with 5-HT2A receptor density. PNAS (PMC10068756)",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
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    {
      "ref": "NPL-114",
      "recordId": "hsi-fd5105023e2775",
      "sourceType": "Journal publication",
      "title": "Baseline Power of Theta Oscillations Predicts Mystical-Type Experiences Induced by DMT in a Natural Setting.",
      "authors": "Tagliazucchi E, Zamberlan F, Cavanna F, de la Fuente L, Romero C, Sanz Perl Y, Pallavicini C.",
      "year": 2021,
      "journal": "Frontiers in psychiatry",
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      "originalCitation": "Pallavicini C et al. (2021). \"Baseline Power of Theta Oscillations Predicts Mystical-Type Experiences Induced by DMT in a Natural Setting.\" Frontiers in Psychiatry",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
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      "corrections": [],
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    {
      "ref": "NPL-115",
      "recordId": "hsi-1f05ba573dcb27",
      "sourceType": "Journal publication",
      "title": "Agonist properties of N,N-dimethyltryptamine at serotonin 5-HT2A and 5-HT2C receptors.",
      "authors": "Smith RL, Canton H, Barrett RJ, Sanders-Bush E.",
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      "pmid": "9768567",
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      "originalCitation": "Smith RL et al. (1998). \"Agonist properties of N,N-dimethyltryptamine at serotonin 5-HT2A and 5-HT2C receptors.\" DMT full agonist at 5-HT2A. Behavioural Brain Research",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-matched",
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      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Agonist+properties+of+N%2CN-dimethyltryptamine+at+serotonin+5-HT2A+and+5-HT2C+receptors%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-116",
      "recordId": "hsi-fe9beed0c48feb",
      "sourceType": "Bibliographic source",
      "title": "Barker SA et al. (2019). Endogenous DMT naturally produced in mammalian brain neurons. Scientific Reports (Nature)",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Barker SA et al. (2019). Endogenous DMT naturally produced in mammalian brain neurons. Scientific Reports (Nature)",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-117",
      "recordId": "hsi-ac1a12e6336bc8",
      "sourceType": "Journal publication",
      "title": "Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.",
      "authors": "Vargas MV, Dunlap LE, Dong C, Carter SJ, Tombari RJ, Jami SA, Cameron LP, Patel SD, Hennessey JJ, Saeger HN, McCorvy JD, Gray JA, Tian L, Olson DE.",
      "year": 2023,
      "journal": "Science (New York, N.Y.)",
      "doi": "10.1126/science.adf0435",
      "pmid": "36795823",
      "pmcid": "PMC10108900",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Olson DE et al. (2023). \"Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.\" Science",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/36795823/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Psychedelics+promote+neuroplasticity+through+the+activation+of+intracellular+5-HT2A+receptors%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-118a",
      "recordId": "hsi-58c1b04eae1511",
      "sourceType": "Journal publication",
      "title": "Acoustical resonances of assorted ancient structures",
      "authors": "Robert G. Jahn; Paul Devereux; Michael Ibison",
      "year": 1996,
      "journal": "The Journal of the Acoustical Society of America",
      "doi": "10.1121/1.414642",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Jahn RG, Devereux P, Ibison M (1996). \"Acoustical resonances of assorted ancient structures.\" Journal of the Acoustical Society of America 99(2):649–658 — ICRL Project 1995–1996: measured fundamental acoustic resonance of Newgrange, Wayland's Smithy, and other Neolithic chambers at ~110 Hz",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.1121/1.414642",
      "metadataURL": "https://api.crossref.org/works?query.title=Acoustical+resonances+of+assorted+ancient+structures&rows=3",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-118b",
      "recordId": "hsi-8df714c2a5352f",
      "sourceType": "Bibliographic source",
      "title": "ICRL/Dragon Project/Metageum Joint Project: Acoustic measurements at the Ħal Saflieni Hypogeum, Malta",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Devereux P et al. (2007). ICRL/Dragon Project/Metageum Joint Project: Acoustic measurements at the Ħal Saflieni Hypogeum, Malta — confirmed Oracle Room resonance at ~110 Hz. [Note: original NPL-118 attributed this to \"Cambridge University archaeoacoustics programme (2008)\" — correct attribution is ICRL, Princeton, with field work 1995–2007]",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-119",
      "recordId": "hsi-02ab11b6d0ef93",
      "sourceType": "Journal publication",
      "title": "Ancient Architectural Acoustic Resonance Patterns and Regional Brain Activity",
      "authors": "Ian A. Cook; Sarah K. Pajot; Andrew F. Leuchter",
      "year": 2008,
      "journal": "Time and Mind",
      "doi": "10.2752/175169608783489099",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Cook IA, Pajot SK, Leuchter AF (2008). \"Ancient Architectural Acoustic Resonance Patterns and Regional Brain Activity.\" Time and Mind 1(1):95–104 — EEG pilot study (n=30): 110 Hz produced significantly lower left temporal activity and prefrontal asymmetry shift from left to right hemispheric dominance compared to 90, 100, 120, 130 Hz tones. [Note: study tested 110 Hz, not 111 Hz; body text references to \"111 Hz\" for this study should be reviewed]",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.2752/175169608783489099",
      "metadataURL": "https://api.crossref.org/works?query.title=Ancient+Architectural+Acoustic+Resonance+Patterns+and+Regional+Brain+Activity&rows=3",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-120",
      "recordId": "hsi-a4e2cdb5885ae2",
      "sourceType": "Journal publication",
      "title": "Effects of Geometric Sound on Brainwave Activity Patterns, Autonomic Nervous System Markers, Emotional Response, and Faraday Wave Pattern Morphology.",
      "authors": "Geffen R, Braun C.",
      "year": 2024,
      "journal": "Evidence-based complementary and alternative medicine : eCAM",
      "doi": "10.1155/2024/9844809",
      "pmid": "38586300",
      "pmcid": "PMC10997421",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Geffen N et al. (2024). \"Effects of Geometric Sound on Brainwave Activity Patterns, Autonomic Nervous System Markers, Emotional Response, and Faraday Wave Pattern Morphology.\" 111 Hz: serotonin +10%, oxytocin +5%. Evidence-Based Complementary and Alternative Medicine (Wiley) (PMC10997421)",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/38586300/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC10997421&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-121",
      "recordId": "hsi-a6e8dbdcc31098",
      "sourceType": "Review",
      "title": "N, N-Dimethyltryptamine (DMT), an Endogenous Hallucinogen: Past, Present, and Future Research to Determine Its Role and Function.",
      "authors": "Barker SA.",
      "year": 2018,
      "journal": "Frontiers in neuroscience",
      "doi": "10.3389/fnins.2018.00536",
      "pmid": "30127713",
      "pmcid": "PMC6088236",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Barker SA (2018). \"N,N-Dimethyltryptamine (DMT), an Endogenous Hallucinogen: Past, Present, and Future Research.\" DMT binding: ~6 µM SERT/SLC6A4, ~22 µM DAT. Frontiers in Neuroscience (PMC5048497)",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-reconciled",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/30127713/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.3389%2Ffnins.2018.00536%22&format=json&resultType=core&pageSize=4",
      "corrections": [
        "Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison.",
        "The originally supplied PMCID points to a different DMT review; the Barker 2018 title was resolved separately.",
        "Published title reconciled with the metadata record."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-122",
      "recordId": "hsi-6a797a12e4bebc",
      "sourceType": "Journal publication",
      "title": "DMT alters cortical travelling waves.",
      "authors": "Alamia A, Timmermann C, Nutt DJ, VanRullen R, Carhart-Harris RL.",
      "year": 2020,
      "journal": "eLife",
      "doi": "10.7554/elife.59784",
      "pmid": "33043883",
      "pmcid": "PMC7577737",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Alamia A, Timmermann C, Nutt DJ, Lutz A, Lorincz ML, Carhart-Harris RL (2020). \"DMT alters cortical travelling waves.\" eLife 9:e59784 (PMID 33043883; PMC7577737) — [Note: original citation attributed to \"Schenberg EE\" — corrected to Alamia A et al. as verified first author]",
      "originalSection": "111 Hz Gamma-Band, Serotonergic/DMT Pathways",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/33043883/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID%3A33043883+AND+SRC%3AMED&format=json&resultType=core&pageSize=4",
      "corrections": [
        "Publication notice: Erratum in; 33164747"
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-123",
      "recordId": "hsi-a9cb2f5e34a281",
      "sourceType": "Bibliographic source",
      "title": "Baker D, Rice S, Sadler N, Cooper J, Wade D (2017). The Next Post: Young people transitioning from military service and their mental health. Orygen / Phoenix Australia. ISBN 978-1-920718-45-9. p. 15: Barriers to mental health service access",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Baker D, Rice S, Sadler N, Cooper J, Wade D (2017). The Next Post: Young people transitioning from military service and their mental health. Orygen / Phoenix Australia. ISBN 978-1-920718-45-9. p. 15: Barriers to mental health service access — cost, culture/stigma, awareness, geographic location, and specific barriers for young men",
      "originalSection": "Mental Health Service Access Barriers",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-124",
      "recordId": "hsi-fdcf14e03d75d0",
      "sourceType": "Bibliographic source",
      "title": "Generative AI and the Future of Work",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Brynjolfsson E, McAfee A (2023). \"Generative AI and the Future of Work.\" Stanford Digital Economy Lab / NBER Working Paper",
      "originalSection": "AI, Job Displacement, and Value Redistribution",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-125",
      "recordId": "hsi-6df09691312824",
      "sourceType": "Bibliographic source",
      "title": "The Potentially Large Effects of Artificial Intelligence on Economic Growth",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Goldman Sachs (2023). \"The Potentially Large Effects of Artificial Intelligence on Economic Growth.\" Global Economics Analyst",
      "originalSection": "AI, Job Displacement, and Value Redistribution",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-126",
      "recordId": "hsi-383199709ef6f4",
      "sourceType": "Journal publication",
      "title": "Robots and Jobs: Evidence from US Labor Markets",
      "authors": "Daron Acemoglu; Pascual Restrepo",
      "year": 2017,
      "journal": "SSRN Electronic Journal",
      "doi": "10.2139/ssrn.2940245",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Acemoglu D, Restrepo P (2020). \"Robots and Jobs: Evidence from US Labor Markets.\" Journal of Political Economy 128(6):2188–2244",
      "originalSection": "AI, Job Displacement, and Value Redistribution",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.2139/ssrn.2940245",
      "metadataURL": "https://api.crossref.org/works?query.title=Robots+and+Jobs%3A+Evidence+from+US+Labor+Markets&rows=3",
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-127",
      "recordId": "hsi-93f7d121a0ab35",
      "sourceType": "Bibliographic source",
      "title": "Sizing the Prize: PwC's Global Artificial Intelligence Study",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "PwC (2024). \"Sizing the Prize: PwC's Global Artificial Intelligence Study.\" PwC Global Report",
      "originalSection": "AI, Job Displacement, and Value Redistribution",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-128",
      "recordId": "hsi-3f248c769cb7e5",
      "sourceType": "Bibliographic source",
      "title": "Evaluating the Impact of AI on the Labor Market: Current State of Affairs",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Gimbel M, Kinder M, Kendall J, Lee M (2025). \"Evaluating the Impact of AI on the Labor Market: Current State of Affairs.\" The Budget Lab at Yale. Analysis of U.S. occupational mix change since ChatGPT release (Nov 2022), finding no economy-wide employment disruption after 33 months; occupational change pace only ~1 percentage point above internet-era comparison; OpenAI exposure and Anthropic usage data show stable employment shares across AI-exposed occupations. [Note: original citation claimed Yale Budget Lab analysed \"policy frameworks for redistributing AI-driven productivity gains, including universal basic income, negative income taxation, and sovereign wealth models\" — no such publication exists; replaced with verified Yale Budget Lab AI research]",
      "originalSection": "AI, Job Displacement, and Value Redistribution",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-129",
      "recordId": "hsi-587c00ecc00816",
      "sourceType": "Bibliographic source",
      "title": "Kelton S (2020). The Deficit Myth: Modern Monetary Theory and the Birth of the People's Economy. PublicAffairs",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Kelton S (2020). The Deficit Myth: Modern Monetary Theory and the Birth of the People's Economy. PublicAffairs",
      "originalSection": "Sovereign Guarantees, MMT, and Oracle Architecture",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-130",
      "recordId": "hsi-3bbc732bf7d08f",
      "sourceType": "Bibliographic source",
      "title": "Wray LR (2015). Modern Money Theory: A Primer on Macroeconomics for Sovereign Monetary Systems. 2nd ed. Palgrave Macmillan",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Wray LR (2015). Modern Money Theory: A Primer on Macroeconomics for Sovereign Monetary Systems. 2nd ed. Palgrave Macmillan",
      "originalSection": "Sovereign Guarantees, MMT, and Oracle Architecture",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-131",
      "recordId": "hsi-0c6e4452422469",
      "sourceType": "Bibliographic source",
      "title": "Mosler WB (1993). Soft Currency Economics.",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Mosler WB (1993). Soft Currency Economics. — Foundational MMT framework for sovereign currency issuance",
      "originalSection": "Sovereign Guarantees, MMT, and Oracle Architecture",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-132",
      "recordId": "hsi-ce00f43b88b08e",
      "sourceType": "Bibliographic source",
      "title": "Tcherneva PR (2020). The Case for a Job Guarantee. Polity Press",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Tcherneva PR (2020). The Case for a Job Guarantee. Polity Press — MMT-informed direct employment as automatic stabiliser during structural transformation",
      "originalSection": "Sovereign Guarantees, MMT, and Oracle Architecture",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-133",
      "recordId": "hsi-b2caf4e538d889",
      "sourceType": "Bibliographic source",
      "title": "MIGA Convention (1985) / World Bank Group (2024). MIGA Annual Report 2023.",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "MIGA Convention (1985) / World Bank Group (2024). MIGA Annual Report 2023. — Sovereign investment guarantees for developing economies and fragile states",
      "originalSection": "Sovereign Guarantees, MMT, and Oracle Architecture",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "role": "Related context in complete bibliography"
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    {
      "ref": "NPL-134",
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      "sourceType": "Bibliographic source",
      "title": "Chainlink: A Decentralized Oracle Network",
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      "originalCitation": "Nazarov S, Ellis A (2017). \"Chainlink: A Decentralized Oracle Network.\" Chainlink Whitepaper — Decentralised oracle architecture for smart contract external data",
      "originalSection": "Sovereign Guarantees, MMT, and Oracle Architecture",
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    {
      "ref": "NPL-135",
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      "sourceType": "Bibliographic source",
      "title": "Cross-Chain Interoperability Protocol (CCIP)",
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      "originalCitation": "Chainlink Labs (2023). \"Cross-Chain Interoperability Protocol (CCIP).\" Chainlink Technical Documentation — Multi-chain CBDC bridge architecture",
      "originalSection": "Sovereign Guarantees, MMT, and Oracle Architecture",
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    },
    {
      "ref": "NPL-136",
      "recordId": "hsi-08604531a6bb4f",
      "sourceType": "Bibliographic source",
      "title": "Decentralized Identifiers (DIDs) v1.0: Core architecture, data model, and representations",
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      "originalCitation": "W3C (2022). \"Decentralized Identifiers (DIDs) v1.0: Core architecture, data model, and representations.\" World Wide Web Consortium Recommendation — Standard for self-sovereign digital identity enabling individuals to create, own, and control identifiers without centralised authorities",
      "originalSection": "Self-Sovereign Identity and Genomic Authentication",
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    },
    {
      "ref": "NPL-137",
      "recordId": "hsi-5b22e3b360013a",
      "sourceType": "Bibliographic source",
      "title": "The Path to Self-Sovereign Identity",
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      "originalCitation": "Allen C (2016). \"The Path to Self-Sovereign Identity.\" Life With Alacrity — Foundational principles of self-sovereign identity: existence, control, access, transparency, persistence, portability, interoperability, consent, minimisation, and protection",
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    },
    {
      "ref": "NPL-138",
      "recordId": "hsi-881adcbbeae56a",
      "sourceType": "Bibliographic source",
      "title": "Preukschat A, Reed D (2021). Self-Sovereign Identity: Decentralized Digital Identity and Verifiable Credentials. Manning Publications",
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      "originalCitation": "Preukschat A, Reed D (2021). Self-Sovereign Identity: Decentralized Digital Identity and Verifiable Credentials. Manning Publications — Comprehensive technical framework for SSI architectures combining decentralised identifiers with verifiable credentials",
      "originalSection": "Self-Sovereign Identity and Genomic Authentication",
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    {
      "ref": "NPL-139",
      "recordId": "hsi-1ab85ffdd4e0cf",
      "sourceType": "Bibliographic source",
      "title": "WHO (2022). World Mental Health Report: Transforming Mental Health for All. World Health Organization",
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      "originalCitation": "WHO (2022). World Mental Health Report: Transforming Mental Health for All. World Health Organization — Global shortfall of 1.2+ million mental health workers; fewer than 2 per 100,000 population in low- and middle-income countries",
      "originalSection": "Robotic and IoT-Based Mental Health Delivery",
      "metadataStatus": "documentary-source",
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      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [],
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    },
    {
      "ref": "NPL-140",
      "recordId": "pmid-28588005",
      "sourceType": "Journal publication",
      "title": "Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial",
      "authors": "Kathleen Kara Fitzpatrick; Alison Darcy; Molly Vierhile",
      "year": 2017,
      "journal": "JMIR Mental Health",
      "doi": "10.2196/mental.7785",
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      "originalCitation": "Fitzpatrick KK, Darcy A, Vierhile M (2017). \"Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression via a Fully Automated Conversational Agent (Woebot): A Randomized Clinical Trial.\" JMIR Mental Health 4(2):e19 — Users disclosed mental health concerns to AI chatbot at rates comparable to human clinicians with reduced stigma",
      "originalSection": "Robotic and IoT-Based Mental Health Delivery",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Published title reconciled with the metadata record."
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    },
    {
      "ref": "NPL-141",
      "recordId": "hsi-e850baebbfec10",
      "sourceType": "Review",
      "title": "Chatbots and Conversational Agents in Mental Health: A Review of the Psychiatric Landscape.",
      "authors": "Vaidyam AN, Wisniewski H, Halamka JD, Kashavan MS, Torous JB.",
      "year": 2019,
      "journal": "Canadian journal of psychiatry. Revue canadienne de psychiatrie",
      "doi": "10.1177/0706743719828977",
      "pmid": "30897957",
      "pmcid": "PMC6610568",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Vaidyam AN, Wisniewski H, Halamka JD, Kashavan MS, Torous JB (2019). \"Chatbots and Conversational Agents in Mental Health: A Review of the Psychiatric Landscape.\" Canadian Journal of Psychiatry 64(7):456–464 — Review of AI conversational agents for mental health applications; reduced stigma in digital disclosure environments",
      "originalSection": "Robotic and IoT-Based Mental Health Delivery",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/30897957/",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-142",
      "recordId": "hsi-8042baa9bf1d2d",
      "sourceType": "Review",
      "title": "Interactions With Robots: The Truths We Reveal About Ourselves.",
      "authors": "Broadbent E.",
      "year": 2017,
      "journal": "Annual review of psychology",
      "doi": "10.1146/annurev-psych-010416-043958",
      "pmid": "27648986",
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      "originalCitation": "Broadbent E (2017). \"Interactions With Robots: The Truths We Reveal About Ourselves.\" Annual Review of Psychology 68:627–652 — Embodied robots enhance therapeutic engagement, disclosure, and sustained alliance versus screen-based agents",
      "originalSection": "Robotic and IoT-Based Mental Health Delivery",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/27648986/",
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      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-143",
      "recordId": "hsi-ba7873fe043fbf",
      "sourceType": "Journal publication",
      "title": "Improving social skills in children with ASD using a long-term, in-home social robot.",
      "authors": "Scassellati B, Boccanfuso L, Huang CM, Mademtzi M, Qin M, Salomons N, Ventola P, Shic F.",
      "year": 2018,
      "journal": "Science robotics",
      "doi": "10.1126/scirobotics.aat7544",
      "pmid": "33141724",
      "pmcid": "PMC10957097",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Scassellati B, Boccanfuso L, Huang CM et al. (2018). \"Improving social skills in children with ASD using a long-term, in-home social robot.\" Science Robotics 3(21):eaat7544 — Long-term therapeutic robot engagement demonstrated sustained outcomes in home settings for mental health and developmental applications",
      "originalSection": "Robotic and IoT-Based Mental Health Delivery",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/33141724/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Improving+social+skills+in+children+with+ASD+using+a+long-term%2C+in-home+social+robot%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": null,
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    },
    {
      "ref": "NPL-144",
      "recordId": "hsi-06c534edea044e",
      "sourceType": "Bibliographic source",
      "title": "Optimus Gen 2 Humanoid Robot",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Tesla (2024). \"Optimus Gen 2 Humanoid Robot.\" Tesla AI — 8-camera vision-only FSD neural network stack; forecast production of 1 billion humanoid robots within the next decade; hardware-agnostic computer vision architecture compatible with camera-based biometric inference pipelines",
      "originalSection": "Robotic and IoT-Based Mental Health Delivery",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
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      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-145",
      "recordId": "hsi-e5ce75d3c77c19",
      "sourceType": "Institutional, commercial or web source",
      "title": "MEMS Fabry-Pérot interferometer-based hyperspectral mobile device",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Rissanen A et al. / VTT Technical Research Centre of Finland (2016). \"MEMS Fabry-Pérot interferometer-based hyperspectral mobile device.\" optics.org (November 2016) — First hyperspectral mobile device via MEMS FPI filter integrated into iPhone camera lens module; health applications identified as target domain",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "http://optics.org",
      "metadataURL": null,
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        "Institutional, product or web reference; no journal-publication identity is asserted."
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      "topicId": "imaging-evolution",
      "role": "Focused chapter source"
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    {
      "ref": "NPL-146",
      "recordId": "hsi-c644e5401b9e2e",
      "sourceType": "Institutional, commercial or web source",
      "title": "Unispectral (Israel) (2016–present). MEMS tuneable Fabry-Pérot filter technology for OEM smartphone camera module integration. Monarch Pro, Neptune, Solomon platforms. unispectral.com",
      "authors": null,
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      "journal": null,
      "doi": null,
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      "originalCitation": "Unispectral (Israel) (2016–present). MEMS tuneable Fabry-Pérot filter technology for OEM smartphone camera module integration. Monarch Pro, Neptune, Solomon platforms. unispectral.com — Demonstrates HSI filter manufacturing at smartphone camera module scale without form factor increase",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "http://unispectral.com",
      "metadataURL": null,
      "corrections": [],
      "topicId": "imaging-evolution",
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    {
      "ref": "NPL-147",
      "recordId": "hsi-2d7983e4ef049a",
      "sourceType": "Institutional, commercial or web source",
      "title": "Consumer Physics (Israel) / SCiO (2014–present). Pocket-sized NIR molecular spectrometer; Kickstarter ~US$2.7M (2014); embedded in Changhong H2 smartphone (CES 2017); matured to commercial platform with 10,000+ users, 50+ countries, millions of analyses. scionir.com",
      "authors": null,
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      "journal": null,
      "doi": null,
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      "originalCitation": "Consumer Physics (Israel) / SCiO (2014–present). Pocket-sized NIR molecular spectrometer; Kickstarter ~US$2.7M (2014); embedded in Changhong H2 smartphone (CES 2017); matured to commercial platform with 10,000+ users, 50+ countries, millions of analyses. scionir.com — Agricultural/food NIR spectroscopy at consumer scale",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "http://scionir.com",
      "metadataURL": null,
      "corrections": [],
      "topicId": "imaging-evolution",
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    {
      "ref": "NPL-148",
      "recordId": "hsi-e3944b33936175",
      "sourceType": "Bibliographic source",
      "title": "Apple iPhone X TrueDepth Camera Teardown",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "System Plus Consulting / Yole Développement (2017). \"Apple iPhone X TrueDepth Camera Teardown.\" Elisabeth S (December 2017) — STMicroelectronics NIR camera sensor (Imager-SOI substrate from SOITEC, sub-4 µm pixels, ~2 MP, high NIR QE) + IR dot projector (~30,000 dots) confirmed at billion-unit manufacturing scale",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "documentary-source",
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      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
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      "topicId": "imaging-evolution",
      "role": "Focused chapter source"
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    {
      "ref": "NPL-149",
      "recordId": "hsi-4b75613536363d",
      "sourceType": "Institutional, commercial or web source",
      "title": "FLIR ONE Gen 3 Thermal Camera",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Teledyne FLIR (2014–present). \"FLIR ONE Gen 3 Thermal Camera.\" flir.com — 80×60 thermal resolution, LWIR 8–14 µm, MSX® multi-spectral fusion, 34×67×14 mm / 36 g smartphone attachment with open developer SDK; thermal band only (no molecular/biomarker inference)",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "http://flir.com",
      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
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      "topicId": "imaging-evolution",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-150",
      "recordId": "hsi-92cd98c0974786",
      "sourceType": "Journal publication",
      "title": "Low-Cost Hyperspectral Imaging with A Smartphone.",
      "authors": "Stuart MB, McGonigle AJS, Davies M, Hobbs MJ, Boone NA, Stanger LR, Zhu C, Pering TD, Willmott JR.",
      "year": 2021,
      "journal": "Journal of imaging",
      "doi": "10.3390/jimaging7080136",
      "pmid": "34460772",
      "pmcid": "PMC8404918",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Stuart MB, McGonigle AJS et al. (2021). \"Low-Cost Hyperspectral Imaging with A Smartphone.\" Journal of Imaging 7(8):136 (MDPI) — 3D-printed smartphone HSI attachment at ~£100 total cost; proves HSI can be added to consumer smartphones without specialised manufacturing",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/34460772/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Low-Cost+Hyperspectral+Imaging+with+A+Smartphone%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "imaging-evolution",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-151",
      "recordId": "hsi-a911e8605e024c",
      "sourceType": "Journal publication",
      "title": "Smartphone-based hyperspectral imaging for ice sheet and proglacial applications in South-West Greenland.",
      "authors": "Stuart MB, Davies M, Fisk C, Allen E, Sole AJ, Ing R, Hobbs MJ, Willmott JR.",
      "year": 2024,
      "journal": "The Science of the total environment",
      "doi": "10.1016/j.scitotenv.2024.175516",
      "pmid": "39147066",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Stuart MB et al. (2024). \"Field deployment of a smartphone hyperspectral imaging attachment in South-West Greenland.\" Science of the Total Environment 951:175516 (ScienceDirect) — Operational reliability of smartphone HSI in extreme field conditions for ice sheet and proglacial environmental analysis",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "metadata-reconciled",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/39147066/",
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      "corrections": [
        "Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison.",
        "Published title reconciled with the metadata record."
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      "topicId": "imaging-evolution",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-152",
      "recordId": "hsi-c2365ea769851d",
      "sourceType": "Journal publication",
      "title": "Quantum dot-enabled infrared hyperspectral imaging with single-pixel detection.",
      "authors": "Meng H, Gao Y, Wang X, Li X, Wang L, Zhao X, Sun B.",
      "year": 2024,
      "journal": "Light, science & applications",
      "doi": "10.1038/s41377-024-01476-4",
      "pmid": "38802359",
      "pmcid": "PMC11130170",
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      "originalCitation": "Meng H, Gao Y et al. (2024). \"Colloidal quantum dot infrared hyperspectral imaging via single-pixel inference.\" Light: Science & Applications (Nature) 13:121 — CQD filters with 128×128 pixel HSI at 8.59 nm spectral resolution across 1050–1630 nm SWIR; miniaturisable architecture compatible with smartphone integration",
      "originalSection": "Hyperspectral Imaging via Smartphone",
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        "Published title reconciled with the metadata record."
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      "topicId": "imaging-evolution",
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      "recordId": "hsi-fda6f081ed5bea",
      "sourceType": "Journal publication",
      "title": "Hyperspectral Information Extraction With Full Resolution From Arbitrary Photographs.",
      "authors": "Kwon S, Mok Park S, Ji Y, Sakthivel H, Woo Leem J, Kim YL.",
      "year": 2025,
      "journal": "IEEE transactions on image processing : a publication of the IEEE Signal Processing Society",
      "doi": "10.1109/tip.2025.3597038",
      "pmid": "40828724",
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      "originalCitation": "Kwon S, Kim YL (2025). \"Hyperspectral Information Extraction From Standard Photographs With Full Resolution.\" IEEE Transactions on Image Processing (ieeexplore.ieee.org/document/11125864) — Formal IEEE peer-reviewed publication: 1–2 nm spectral resolution from standard RGB cameras via colour reference chart; no hardware modification required",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "metadata-reconciled",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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        "Published title reconciled with the metadata record."
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      "topicId": "spectral-reconstruction",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-154",
      "recordId": "hsi-852a0ba2dbf56c",
      "sourceType": "Institutional, commercial or web source",
      "title": "Scyllarus: Hyperspectral Image Processing Platform",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "CSIRO Data61 (2016–present). \"Scyllarus: Hyperspectral Image Processing Platform.\" scyllarus.data61.csiro.au — Obtains hyperspectral data from standard IoT cameras including smartphone cameras via computer vision and machine learning; C++ API, MATLAB toolbox, Scyven viewer; deployed for agricultural disease inference and forensic analysis",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "documentary-source",
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      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": "spectral-reconstruction",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-155",
      "recordId": "hsi-4f3065875d9c72",
      "sourceType": "Book or chapter",
      "title": "Distributed Ledgers",
      "authors": "Robert M. Townsend",
      "year": 2020,
      "journal": "",
      "doi": "10.7551/mitpress/13382.001.0001",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "CSIRO Data61 (2019). \"Distributed Ledgers\" whitepaper. csiro.au/-/media/D61/Files/Distributed-Ledgers.pdf — Confirms Scyllarus platform capability for spectral analysis from standard cameras; BK met with CSIRO Data61 in 2019 regarding building technology with Scyllarus platform",
      "originalSection": "Hyperspectral Imaging via Smartphone",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Author attribution differs from the public metadata; canonical authors are shown in source details."
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      "topicId": "spectral-reconstruction",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-156",
      "recordId": "hsi-21970c827acaf2",
      "sourceType": "Institutional, commercial or web source",
      "title": "Affectiva / Smart Eye (2009–present). MIT Media Lab spinoff; 17.4M face videos analysed; FACS-based facial emotion recognition; adopted by 90% of world's largest advertisers. Acquired by Smart Eye (2021). affectiva.com",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
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      "originalAssignee": null,
      "originalCitation": "Affectiva / Smart Eye (2009–present). MIT Media Lab spinoff; 17.4M face videos analysed; FACS-based facial emotion recognition; adopted by 90% of world's largest advertisers. Acquired by Smart Eye (2021). affectiva.com",
      "originalSection": "Facial Emotion Recognition Engines",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "http://affectiva.com",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-157",
      "recordId": "hsi-9aca948efa6310",
      "sourceType": "Bibliographic source",
      "title": "Apple Buys AI Startup That Reads Emotions in Faces",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Apple / Emotient acquisition (January 2016). \"Apple Buys AI Startup That Reads Emotions in Faces.\" Wired (7 January 2016); CNBC (8 January 2016). San Diego startup; crowdsourced ML for facial emotion recognition; integrated into Apple R&D pipeline",
      "originalSection": "Facial Emotion Recognition Engines",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-158",
      "recordId": "hsi-3d3b5bdc1825c3",
      "sourceType": "Bibliographic source",
      "title": "Comparing Emotion Recognition Tech: Microsoft, Neurodata Lab, Amazon, Affectiva",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
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      "originalAssignee": null,
      "originalCitation": "Neurodata Lab (2019). \"Comparing Emotion Recognition Tech: Microsoft, Neurodata Lab, Amazon, Affectiva.\" Medium — Independent benchmarking across 7 emotion categories: Microsoft Azure Face API ranked first, Neurodata Lab second, Affectiva and Amazon Rekognition trailing",
      "originalSection": "Facial Emotion Recognition Engines",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
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      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-159",
      "recordId": "hsi-ed18598f8b5617",
      "sourceType": "Bibliographic source",
      "title": "Key Companies in Artificial Intelligence in Emotion Inference",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Research and Markets (2024). \"Key Companies in Artificial Intelligence in Emotion Inference.\" — Market forecast: USD 3.57B by 2030 for AI-based emotion inference technologies",
      "originalSection": "Facial Emotion Recognition Engines",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-160",
      "recordId": "hsi-509cb5093173a7",
      "sourceType": "Institutional, commercial or web source",
      "title": "Kintsugi Health (2021–present). Voice biomarker API for depression and anxiety inference via short speech samples during routine phone/video interactions. Forbes AI 50. Published in Annals of Family Medicine. kintsugihealth.com",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Kintsugi Health (2021–present). Voice biomarker API for depression and anxiety inference via short speech samples during routine phone/video interactions. Forbes AI 50. Published in Annals of Family Medicine. kintsugihealth.com",
      "originalSection": "Vocal Biomarker Technologies for Mental Health",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "http://kintsugihealth.com",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-161",
      "recordId": "hsi-2d7228bf087a2d",
      "sourceType": "Institutional, commercial or web source",
      "title": "Sonde Health (2017–present). Vocal biomarker platform for mental fitness scoring and tracking; 1M+ voice recordings, 80K+ individuals; measures pitch, vocal control, liveliness, energy, clarity. sondehealth.com",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Sonde Health (2017–present). Vocal biomarker platform for mental fitness scoring and tracking; 1M+ voice recordings, 80K+ individuals; measures pitch, vocal control, liveliness, energy, clarity. sondehealth.com",
      "originalSection": "Vocal Biomarker Technologies for Mental Health",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "http://sondehealth.com",
      "metadataURL": null,
      "corrections": [],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-162",
      "recordId": "hsi-68920f19acc589",
      "sourceType": "Bibliographic source",
      "title": "Vocal Biomarkers for Mental Health",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "American Psychiatric Association (January 2026). \"Vocal Biomarkers for Mental Health.\" APA Blogs — Identifies vocal biomarkers as promising frontier for mental health screening; notes clinical readiness not yet established",
      "originalSection": "Vocal Biomarker Technologies for Mental Health",
      "metadataStatus": "documentary-source",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [
        "Institutional, product or web reference; no journal-publication identity is asserted."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-163",
      "recordId": "hsi-8c4a775b474639",
      "sourceType": "Review",
      "title": "Use of voice features from smartphones for monitoring depressive disorders: Scoping review.",
      "authors": "Shin J, Bae SM.",
      "year": 2024,
      "journal": "Digital health",
      "doi": "10.1177/20552076241261920",
      "pmid": "38882248",
      "pmcid": "PMC11179519",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Low DM et al. (2024). \"Smartphone-derived voice features for depression monitoring: A scoping review.\" PMC (PMC11179519) — Smartphone voice features show promise for depression monitoring; sole predictive power requires further validation",
      "originalSection": "Vocal Biomarker Technologies for Mental Health",
      "metadataStatus": "metadata-reconciled",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/38882248/",
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        "Published title reconciled with the metadata record.",
        "Author attribution differs from the public metadata; canonical authors are shown in source details."
      ],
      "topicId": null,
      "role": "Related context in complete bibliography"
    },
    {
      "ref": "NPL-164",
      "recordId": "hsi-bb8bd49cde6956",
      "sourceType": "Conference publication",
      "title": "Practical RGB Measurement of Fluorescence and Blood Distributions in Skin",
      "authors": "Emilie Nogué; Arvin Lin; Xiaohui Li; Giuseppe Claudio Guarnera; Abhijeet Ghosh",
      "year": 2024,
      "journal": "Color and Imaging Conference",
      "doi": "10.2352/cic.2024.32.1.24",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Nogué S, Maguire C, Sherlock A et al. (2024). \"Practical RGB Measurement of Fluorescence and Blood Distributions in Skin.\" Color and Imaging Conference 32(1):133–141 — Commodity RGB cameras isolate elastin fluorescence + haemoglobin/melanin chromophores via Donaldson re-radiation matrices; no UV capture or dense hyperspectral rig required",
      "originalSection": "RGB Measurement of Fluorescence and Blood Distributions in Skin",
      "metadataStatus": "metadata-reconciled",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.2352/cic.2024.32.1.24",
      "metadataURL": "https://api.crossref.org/works/10.2352%2FCIC.2024.32.1.24",
      "corrections": [
        "Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison."
      ],
      "topicId": "optical-physiology",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-165",
      "recordId": "hsi-db701719d4dfca",
      "sourceType": "Journal publication",
      "title": "Development of a Smartphone-Linked Immunosensing System for Oxytocin Determination.",
      "authors": "Sarubo M, Suzuki Y, Numazaki Y, Kudo H.",
      "year": 2025,
      "journal": "Biosensors",
      "doi": "10.3390/bios15040261",
      "pmid": "40277575",
      "pmcid": "PMC12025206",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Sarubo K, Ishida Y, Kawano S et al. (2025). \"Smartphone-Linked Optical Immunosensing for Oxytocin Determination in Human Saliva.\" Biosensors 15(4):261 (PMC 12025206) — LED backlight + CMOS camera ELISA readout; inference limit 5.26 pg/mL salivary OXT; r = 0.972 vs conventional ELISA. Invasive (saliva + reagents + physical cell attachment)",
      "originalSection": "Smartphone-Linked Immunosensing for Oxytocin Determination",
      "metadataStatus": "metadata-reconciled",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/40277575/",
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      "corrections": [
        "Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison.",
        "Published title reconciled with the metadata record."
      ],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-166",
      "recordId": "hsi-93d8a400352b6c",
      "sourceType": "Review",
      "title": "Fluorescent visualization of oxytocin in the hypothalamo-neurohypophysial system.",
      "authors": "Hashimoto H, Matsuura T, Ueta Y.",
      "year": 2014,
      "journal": "Frontiers in neuroscience",
      "doi": "10.3389/fnins.2014.00213",
      "pmid": "25100939",
      "pmcid": "PMC4107947",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Hashimoto H, Matsuura T, Ueta Y (2014). \"Fluorescent Visualization of Oxytocin in the Hypothalamo-Neurohypophysial System.\" Frontiers in Neuroscience 8:213 (PMC 4107947) — OXT-mRFP1 transgenic rats; visible fluorescence in hypothalamic OXT neurons and posterior pituitary; 5–7× fluorescence increase with OXT expression under salt loading",
      "originalSection": "Fluorescent Visualisation and Real-Time Sensing of Oxytocin",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC4107947&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-167",
      "recordId": "hsi-8ad27b6daef8ac",
      "sourceType": "Journal publication",
      "title": "A fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain.",
      "authors": "Ino D, Tanaka Y, Hibino H, Nishiyama M.",
      "year": 2022,
      "journal": "Nature methods",
      "doi": "10.1038/s41592-022-01597-x",
      "pmid": "36138174",
      "pmcid": "PMC9550624",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Ino D, Tanaka Y, Hibino H et al. (2022). \"A fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain.\" Nature Methods 19(10):1286–1294 (PMC 9550624) — MTRIA_OT GPCR-based green fluorescent OXT sensor; fiber photometry; ultradian ~2 hr \"OT oscillation\"; intranasal/IP OXT <1% reaches brain",
      "originalSection": "Fluorescent Visualisation and Real-Time Sensing of Oxytocin",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/36138174/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC9550624&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-168",
      "recordId": "hsi-9e3caca1a18860",
      "sourceType": "Journal publication",
      "title": "Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor.",
      "authors": "Santonocito R, Tuccitto N, Pappalardo A, Trusso Sfrazzetto G.",
      "year": 2022,
      "journal": "Molecules (Basel, Switzerland)",
      "doi": "10.3390/molecules27217503",
      "pmid": "36364331",
      "pmcid": "PMC9654496",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Santonocito R, Tuccitto N, Pappalardo A, Trusso Sfrazzetto G (2022). \"Smartphone-Based Dopamine Inference by Fluorescent Supramolecular Sensor.\" Molecules 27(21):7503 (PMC 9654496) — Quinoxaline cavitand (Cav-4-Qx) on siloxane polymer; inference limit 1 pM; linear range 10 mM–100 pM; smartphone camera readout in dark chamber; good selectivity in artificial and real saliva; reusable via acid-base switching. Invasive (saliva + sensor strip + dark chamber)",
      "originalSection": "Smartphone-Based Dopamine Inference by Fluorescent Supramolecular Sensor",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/36364331/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC9654496&format=json&resultType=core&pageSize=4",
      "corrections": [
        "Published title reconciled with the metadata record."
      ],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-169",
      "recordId": "hsi-d472a890e03c1b",
      "sourceType": "Review",
      "title": "Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies.",
      "authors": "Heikal AA.",
      "year": 2010,
      "journal": "Biomarkers in medicine",
      "doi": "10.2217/bmm.10.1",
      "pmid": "20406068",
      "pmcid": "PMC2905054",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Heikal AA (2010). \"Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies.\" Biomarkers in Medicine 4(2):241–263 (PMC 2924670) — NADPH autofluorescence as \"bellwether\" of intracellular redox states; directly couples metabolic activity to optical emission intensity",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/20406068/",
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      "corrections": [
        "A supplied identifier resolved to another title; the accepted record was matched separately by title."
      ],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-170",
      "recordId": "hsi-98a399171f2226",
      "sourceType": "Journal publication",
      "title": "A general model for the origin of allometric scaling laws in biology.",
      "authors": "West GB, Brown JH, Enquist BJ.",
      "year": 1997,
      "journal": "Science (New York, N.Y.)",
      "doi": "10.1126/science.276.5309.122",
      "pmid": "9082983",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "West GB, Brown JH, Enquist BJ (1997). \"A General Model for the Origin of Allometric Scaling Laws in Biology.\" Science 276(5309):122–126 — Fractal-like branching networks govern biological scaling laws from cellular metabolism to whole-organism physiology; theoretical basis for cross-scale signal propagation",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/9082983/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22A+General+Model+for+the+Origin+of+Allometric+Scaling+Laws+in+Biology%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-171",
      "recordId": "hsi-e7e54aaae200fa",
      "sourceType": "Journal publication",
      "title": "Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.",
      "authors": "Unger EK, Keller JP, Altermatt M, Liang R, Matsui A, Dong C, Hon OJ, Yao Z, Sun J, Banala S, Flanigan ME, Jaffe DA, Hartanto S, Carlen J, Mizuno GO, Borden PM, Shivange AV, Cameron LP, Sinning S, Underhill SM, Olson DE, Amara SG, Temple Lang D, Rudnick G, Marvin JS, Lavis LD, Lester HA, Alvarez VA, Fisher AJ, Prescher JA, Kash TL, Yarov-Yarovoy V, Gradinaru V, Looger LL, Tian L.",
      "year": 2020,
      "journal": "Cell",
      "doi": "10.1016/j.cell.2020.11.040",
      "pmid": "33333022",
      "pmcid": "PMC8025677",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Unger EK, Keller JP, Altermatt M et al. (2020). \"Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.\" Cell 183(7):1986–2002 (DOI: 10.1016/j.cell.2020.11.040; Addgene #128483, pRSET-iSeroSnFR, Lin Tian Lab, UC Davis) — ML-guided binding-pocket redesign (Rosetta + random forest + GLM) produced iSeroSnFR genetically encoded fluorescent 5-HT sensor; >5,000× improved affinity over iAChSnFR0.6; 800% ΔF/F₀; ~350 pM inference; millisecond kinetics; fiber photometry in freely behaving mice (fear conditioning, social interaction, sleep/wake); OSTA assay for hSERT/SLC6A4 pharmacology (SSRIs, cocaine, MDMA). Invasive (genetically encoded sensor + viral delivery + implanted fiber optics)",
      "originalSection": "Machine Learning-Directed Fluorescent Serotonin Sensor",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/33333022/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1016%2Fj.cell.2020.11.040%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-172",
      "recordId": "hsi-51ceed09e76ab1",
      "sourceType": "Journal publication",
      "title": "The self-organizing fractal theory as a universal discovery method: the phenomenon of life.",
      "authors": "Kurakin A.",
      "year": 2011,
      "journal": "Theoretical biology & medical modelling",
      "doi": "10.1186/1742-4682-8-4",
      "pmid": "21447162",
      "pmcid": "PMC3080324",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Kurakin A (2011). \"The self-organizing fractal theory as a universal discovery method: the phenomenon of life.\" Theoretical Biology and Medical Modelling 8:4 (PMC 3080324) — Self-organising fractal theory unifying biological organisation from molecular to organismal scale; fractal self-similarity as a universal design principle underlying metabolism, gene expression, and cellular dynamics",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/21447162/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC3080324&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-173",
      "recordId": "hsi-970c306954834e",
      "sourceType": "Journal publication",
      "title": "Temporal metabolic partitioning of the yeast and protist cellular networks: the cell is a global scale-invariant (fractal or self-similar) multioscillator.",
      "authors": "Lloyd D, Murray DB, Aon MA, Cortassa S, Roussel MR, Beckmann M, Poole RK.",
      "year": 2018,
      "journal": "Journal of biomedical optics",
      "doi": "10.1117/1.jbo.24.5.051404",
      "pmid": "30516036",
      "pmcid": "PMC6992908",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Lloyd D, Murray DB, Aon MA, Poole RK (2018). \"Temporal metabolic partitioning of the yeast and protist cellular networks: the cell is a global scale-invariant (fractal or self-similar) multioscillator.\" Journal of Biomedical Optics (ResearchGate DOI: 10.1117/1.JBO.24.5.051404) — NAD(P)H autofluorescence as \"bellwether of intracellular redox states\"; cell as fractal multioscillator with self-similar temporal organisation from milliseconds to hours; two-photon fluorescence excitation at 740 nm, emission <490 nm for NAD(P)H imaging in cardiomyocytes and yeast",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/30516036/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1117%2F1.JBO.24.5.051404%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-174",
      "recordId": "hsi-f69919e90b4809",
      "sourceType": "Review",
      "title": "A healthy dose of chaos: Using fractal frameworks for engineering higher-fidelity biomedical systems.",
      "authors": "Korolj A, Wu HT, Radisic M.",
      "year": 2019,
      "journal": "Biomaterials",
      "doi": "10.1016/j.biomaterials.2019.119363",
      "pmid": "31376747",
      "pmcid": "PMC6759375",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Korolj A, Wu HT, Radisic M (2019). \"A healthy dose of chaos: Using fractal frameworks for engineering higher-fidelity biomedical systems.\" Biomaterials 219:119363 (PMC 6759375) — Fractal dimension as quantitative health metric across biological systems; fractal frameworks for biomedical engineering; healthy biological systems exhibit characteristic fractal complexity that degrades in disease states",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/31376747/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC6759375&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-175",
      "recordId": "hsi-890a81b217c123",
      "sourceType": "Journal publication",
      "title": "Superresolution intrinsic fluorescence imaging of chromatin utilizing native, unmodified nucleic acids for contrast.",
      "authors": "Dong B, Almassalha LM, Stypula-Cyrus Y, Urban BE, Chandler JE, Nguyen TQ, Sun C, Zhang HF, Backman V.",
      "year": 2016,
      "journal": "Proceedings of the National Academy of Sciences of the United States of America",
      "doi": "10.1073/pnas.1602202113",
      "pmid": "27535934",
      "pmcid": "PMC5024634",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Dong B, Almassalha LM et al. (2016). \"Superresolution intrinsic fluorescence imaging of chromatin utilizing native, unmodified nucleic acids for contrast.\" Proceedings of the National Academy of Sciences 113(35):9716–9721 (DOI: 10.1073/pnas.1602202113) — Label-free DNA partial-wave spectroscopic (PWS) microscopy at sub-20 nm resolution; chromatin follows fractal globule power-law scaling (D ≈ 3) at nanoscale; intrinsic nucleic acid fluorescence used as endogenous contrast for chromatin organisation imaging",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/27535934/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1073%2Fpnas.1602202113%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-176",
      "recordId": "hsi-c847bd10379570",
      "sourceType": "Journal publication",
      "title": "Short-time fractal analysis of biological autoluminescence.",
      "authors": "Dlask M, Kukal J, Poplová M, Sovka P, Cifra M.",
      "year": 2019,
      "journal": "PloS one",
      "doi": "10.1371/journal.pone.0214427",
      "pmid": "31348777",
      "pmcid": "PMC6660117",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Dlask M, Kukal J, Poplová M, Sovka P, Cifra M (2019). \"Short-time fractal analysis of biological autoluminescence.\" PLoS ONE 14(7):e0214427 (PMID 31348777) — Fractal analysis of biological autoluminescence (ultra-weak photon emission) time series; negative memory in photon count signals from germinating mung beans; Hurst exponent analysis reveals anti-persistent fractal dynamics in endogenous biophoton emission",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/31348777/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID%3A31348777+AND+SRC%3AMED&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-177",
      "recordId": "hsi-8b0c28afb02b86",
      "sourceType": "Review",
      "title": "Fractal geometry: a design principle for living organisms.",
      "authors": "Weibel ER.",
      "year": 1991,
      "journal": "The American journal of physiology",
      "doi": "10.1152/ajplung.1991.261.6.l361",
      "pmid": "1767856",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Weibel ER (1991). \"Fractal geometry: a design principle for living organisms.\" American Journal of Physiology 261(6 Pt 1):L361–L369 (PMID 1767856) — Foundational paper: fractal geometry as biological design principle; self-similar branching networks in lungs, vasculature, and bronchial trees; efficient genetic programming of biological form through fractal algorithms; fractal dimension as measure of space-filling efficiency across biological scales",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/1767856/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID%3A1767856+AND+SRC%3AMED&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-178",
      "recordId": "hsi-3338d715ddefac",
      "sourceType": "Preprint",
      "title": "Fractal Analysis of Multiscale Biological Systems",
      "authors": "Muhammad Y.",
      "year": 2024,
      "journal": "",
      "doi": "10.20944/preprints202412.1952.v1",
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Muhammad Y (2024). \"Fractal Analysis of Multiscale Biological Systems.\" Preprints.org 2024121952 (posted 23 December 2024; ResearchGate presentation, Ain Shams University, January 2025) — Comprehensive review of fractal analysis across biological scales: chromatin (fractal globule D ≈ 1.02–1.40 for normal-to-cancerous), cell surface (healthy D ≈ 1.1–1.3, cancerous D ≈ 1.3–1.6), branching networks (circulatory D ≈ 1.6–1.9, lungs D ≈ 1.8–2.2, kidneys D ≈ 1.7–2.0, nervous system D ≈ 1.4–1.6), radiomics, physiological signals; fractal dimension as unique signature for healthy-versus-pathological state transitions",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.20944/preprints202412.1952.v1",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Fractal+Analysis+of+Multiscale+Biological+Systems%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-179",
      "recordId": "hsi-a969f74bedb780",
      "sourceType": "Bibliographic source",
      "title": "A Fractal Approach to Pattern Formation in Biological Systems",
      "authors": null,
      "year": null,
      "journal": null,
      "doi": null,
      "pmid": null,
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Dobrescu R, Ichim L, Mocanu S, Popa S (2008). \"A Fractal Approach to Pattern Formation in Biological Systems.\" WSEAS Transactions on Biology and Biomedicine 5(6):107–116 — Reaction-diffusion systems as fractal pattern generators; connection between morphogenesis, nonlinear dynamics, and fractal structures; diffusion-limited aggregation (DLA) model of bacterial colony growth; attractor theory linking fractal patterns to stable biological states",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "unresolved",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "metadataURL": null,
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-180",
      "recordId": "hsi-c97f9a5a073dee",
      "sourceType": "Journal publication",
      "title": "Characterizing and Quenching Autofluorescence in Fixed Mouse Adrenal Cortex Tissue.",
      "authors": "Sakr N, Glazova O, Shevkova L, Onyanov N, Kaziakhmedova S, Shilova A, Vorontsova MV, Volchkov P.",
      "year": 2023,
      "journal": "International journal of molecular sciences",
      "doi": "10.3390/ijms24043432",
      "pmid": "36834842",
      "pmcid": "PMC9968082",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Sakr N, Glazova O, Shevkova L, Onyanov N, Kaziakhmedova S, Shilova A, Vorontsova MV, Volchkov P (2023). \"Characterizing and Quenching Autofluorescence in Fixed Mouse Adrenal Cortex Tissue.\" International Journal of Molecular Sciences 24(4):3432 (DOI: 10.3390/ijms24043432) — Broad-spectrum endogenous autofluorescence characterisation in adrenal cortex tissue; intracellular fluorophores (lipofuscin, lipids, NADH, flavins) emit across 405–488 nm excitation bands; autofluorescence originates from cortical cell cytoplasm; lipofuscin accumulation increases autofluorescence with age; lambda scanning quantification of autofluorescence emission profiles",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/36834842/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.3390%2Fijms24043432%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-181",
      "recordId": "hsi-a7e89452d57b51",
      "sourceType": "Journal publication",
      "title": "Classifying T cell activity in autofluorescence intensity images with convolutional neural networks.",
      "authors": "Wang ZJ, Walsh AJ, Skala MC, Gitter A.",
      "year": 2020,
      "journal": "Journal of biophotonics",
      "doi": "10.1002/jbio.201960050",
      "pmid": "31661592",
      "pmcid": "PMC7065628",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Wang ZJ, Walsh AJ, Skala MC, Gitter A (2020). \"Classifying T cell activity in autofluorescence intensity images with convolutional neural networks.\" Journal of Biophotonics 13(3):e201960050 (PMC 7065628) — CNN classification of T cell activation states from NAD(P)H autofluorescence intensity images; endogenous metabolic co-enzyme fluorescence reflects immune cell functional state; label-free optical metabolic imaging distinguishes quiescent from activated T cells",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/31661592/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC7065628&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-182",
      "recordId": "hsi-672c477cf92f2c",
      "sourceType": "Review",
      "title": "Fluorescence spectroscopy of neoplastic and non-neoplastic tissues.",
      "authors": "Ramanujam N.",
      "year": 2000,
      "journal": "Neoplasia (New York, N.Y.)",
      "doi": "10.1038/sj.neo.7900077",
      "pmid": "10933071",
      "pmcid": "PMC1531869",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Ramanujam N (2000). \"Fluorescence Spectroscopy of Neoplastic and Non-Neoplastic Tissues.\" Neoplasia 2(1-2):89–117 (PMC 1531869) — Comprehensive review of endogenous tissue fluorophores (NADH, FAD, collagen, elastin, porphyrins) for non-invasive tissue characterisation; fluorophore distributions across tissue architectural layers; spectral signatures distinguish neoplastic from normal tissue; establishes fluorescence spectroscopy as diagnostic tool for tissue state determination",
      "originalSection": "Systems Biology Framework for Fractal Autofluorescence",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/10933071/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC1531869&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-183",
      "recordId": "hsi-b89b11771190f7",
      "sourceType": "Journal publication",
      "title": "[Imaging Analyses of Oxytocin: Visualization of Oxytocin and Its Implications].",
      "authors": "Nuriya M.",
      "year": 2023,
      "journal": "Brain and nerve = Shinkei kenkyu no shinpo",
      "doi": "10.11477/mf.1416202450",
      "pmid": "37537742",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "PMID 37537742 (2023). \"Imaging analyses of oxytocin: alkyne-tagging strategy for visualization of oxytocin and its implications for brain action.\" IGAKU-SHOIN — Alkyne-tagging chemical strategy for direct visualisation of oxytocin distribution; implications for understanding OXT brain action mechanisms",
      "originalSection": "Fluorescent Visualisation and Real-Time Sensing of Oxytocin",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/37537742/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID%3A37537742+AND+SRC%3AMED&format=json&resultType=core&pageSize=4",
      "corrections": [
        "Published title reconciled with the metadata record.",
        "Author attribution differs from the public metadata; canonical authors are shown in source details."
      ],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-184",
      "recordId": "hsi-37b2d379bb9681",
      "sourceType": "Journal publication",
      "title": "Identification of peripheral oxytocin-expressing cells using systemically applied cell-type specific adeno-associated viral vector.",
      "authors": "Paiva L, Lozic M, Allchorne A, Grinevich V, Ludwig M.",
      "year": 2021,
      "journal": "Journal of neuroendocrinology",
      "doi": "10.1111/jne.12970",
      "pmid": "33851744",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "PMID 33851744 (2021). \"Identification of peripheral oxytocin-expressing cells using systemically applied cell-type specific adeno-associated viral vector.\" Journal of Neuroendocrinology — Confirmed OXT expression via fluorescence in enteric nervous system ganglia, pancreatic islets of Langerhans, and testicular Leydig cells using systemically applied AAV vector; demonstrates peripheral OXT-expressing cell populations beyond hypothalamus",
      "originalSection": "Fluorescent Visualisation and Real-Time Sensing of Oxytocin",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/33851744/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID%3A33851744+AND+SRC%3AMED&format=json&resultType=core&pageSize=4",
      "corrections": [
        "Author attribution differs from the public metadata; canonical authors are shown in source details."
      ],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-185",
      "recordId": "hsi-4d0943da705896",
      "sourceType": "Journal publication",
      "title": "Specificity of oxytocin and vasopressin immunofluorescence.",
      "authors": "Swaab DF, Pool CW.",
      "year": 1975,
      "journal": "The Journal of endocrinology",
      "doi": "10.1677/joe.0.0660263",
      "pmid": "1100756",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "PMID 1100756 (1976). \"Specificity of oxytocin and vasopressin immunofluorescence.\" — Classic study on immunofluorescence specificity for OXT and AVP using CNBr-activated agarose beads and quantitative fluorescence measurement; demonstrated antibody purification for specific OXT/AVP visualisation including validation in Brattleboro rats (vasopressin-deficient model)",
      "originalSection": "Fluorescent Visualisation and Real-Time Sensing of Oxytocin",
      "metadataStatus": "metadata-matched",
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      "authors": "Perisic Böhm M, Kalaba P, Gormal RS, Zupančič M, Wolf A, Juračić M, Kremsmayr T, Meunier FA, Langer T, Gruber CW, Keimpema E, Muttenthaler M.",
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      "sourceType": "Journal publication",
      "title": "Digital cutaneous fluorometry: correlation between blood flow and fluorescence.",
      "authors": "Bongard FS, Upton RA, Elings VB, Lewis FR.",
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      "originalCitation": "\"Digital cutaneous fluorometry: Correlation between blood flow and fluorescence.\" Journal of Vascular Surgery 1(5):635–641 (1984) (ScienceDirect PII: 0741521484901289) — Established that tissue fluorescence intensity is linearly related to blood flow using digital cutaneous fluorometry; foundational evidence that perfusion conclusions can be drawn from relative fluorescence measurements in skin",
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      "originalCitation": "Lakowicz JR (2006). Principles of Fluorescence Spectroscopy. 3rd ed. Springer. Ch. 16: \"Protein Fluorescence\" — Tryptophan indole ring (fused hexagonal benzene + pentagonal pyrrole) as dominant intrinsic protein fluorophore; excitation ~280 nm, emission ~340 nm; π→π* transitions of delocalised electrons across aromatic ring geometry; quantum yield sensitivity to local microenvironment; >90% of total protein UV fluorescence from tryptophan; molar extinction coefficient ~5,500 M⁻¹cm⁻¹ at 280 nm",
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      "originalCitation": "Ghisaidoobe ABT, Chung SJ (2014). \"Intrinsic Tryptophan Fluorescence in the Inference and Analysis of Proteins: A Focus on Förster Resonance Energy Transfer Techniques.\" International Journal of Molecular Sciences 15(12):22518–22538 (PMC 4284740) — Comprehensive review of tryptophan intrinsic fluorescence; indole chromophore π→π* transitions; environmental sensitivity of emission wavelength and quantum yield; FRET applications exploiting tryptophan as endogenous donor",
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      "originalCitation": "Vivian JT, Callis PR (2001). \"Mechanisms of Tryptophan Fluorescence Shifts in Proteins.\" Biophysical Journal 80(5):2093–2109 (PMC 1301402) — Computational and experimental analysis of tryptophan fluorescence wavelength shifts; electrostatic interactions between indole ring π-electron system and local protein matrix; charge transfer states modulating emission",
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      "originalCitation": "Callis PR (1997). \"¹Lₐ and ¹L_b Transitions of Tryptophan: Applications of Theory and Experiment.\" Methods in Enzymology 278:113–150 — Theoretical treatment of the two overlapping electronic transitions (¹Lₐ and ¹L_b) in tryptophan indole ring; molecular orbital analysis of π-electron delocalisation pathways across hexagonal and pentagonal ring geometry; transition dipole directions and energies",
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      "originalCitation": "Shah S, Bhatt A, Bhatt S et al. (2023). \"Label-Free Tryptophan Fluorescence Lifetime Imaging as a Marker of Protein Conformational States in Cells.\" — FLIM distinguishing protein conformational states, folding intermediates, and aggregation from endogenous tryptophan autofluorescence in living cells without exogenous labels; demonstrates tryptophan fluorescence lifetime as a non-invasive readout of protein structure and translation state",
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      "sourceType": "Journal publication",
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      "authors": "Simpson JH.",
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      "originalCitation": "Simpson CL (2019). \"Transcriptional Reporters: Watching Gene Expression in Color.\" eLife 8:e49414 (PMC 6660214) — Insight on TransTimer dual-colour fluorescent transcriptional reporter; green-to-red colour shift encoding transcriptional history at single-cell resolution; protein translation as the mechanism linking gene transcription to visible fluorescence",
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      "originalCitation": "Bhogale S, Bhatt T, Bhatt S et al. (2024). \"Tracking and measuring local protein synthesis in vivo.\" Development 151(21) — Review of technologies for direct measurement of nascent protein synthesis including fluorescent reporters, non-canonical amino acid labelling (FUNCAT/BONCAT), ribosome profiling, and single-molecule imaging; establishes protein translation as a measurable, fluorescence-detectable event in living organisms",
      "originalSection": "Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription",
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    {
      "ref": "NPL-195",
      "recordId": "hsi-320858d8be27a8",
      "sourceType": "Journal publication",
      "title": "A protein-tagging system for signal amplification in gene expression and fluorescence imaging.",
      "authors": "Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD.",
      "year": 2014,
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      "originalCitation": "Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD (2014). \"A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging.\" Cell 159(3):635–646 — SunTag: repeating GCN4 peptide epitope array recruiting up to 24 copies of scFv-GFP fusion per translation event; single-molecule imaging of translation dynamics; amplifies fluorescent signal of individual protein translation events to single-molecule detectability",
      "originalSection": "Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription",
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      "ref": "NPL-196",
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      "title": "Understanding Protein Expression",
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      "originalCitation": "Abcam (2025). \"Understanding Protein Expression.\" Abcam Knowledge Center (abcam.com) — Reviews central dogma pipeline (transcription → translation → protein); protein expression systems (bacterial, mammalian, cell-free); post-translational modifications; fluorescent protein tagging as standard methodology for visualising gene expression products",
      "originalSection": "Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription",
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    {
      "ref": "NPL-197",
      "recordId": "hsi-1bfd258cce7eef",
      "sourceType": "Review",
      "title": "Imaging translation in single cells using fluorescent microscopy.",
      "authors": "Chao JA, Yoon YJ, Singer RH.",
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      "originalCitation": "Chao JA, Yoon YJ, Singer RH (2012). \"Imaging Translation in Single Cells Using Fluorescent Microscopy.\" Cold Spring Harbor Perspectives in Biology 4(11):a012310 (PMC 3536344) — FUNCAT, fluorescent puromycin, fl-tRNA FRET, photoconvertible reporters, MS2/PP7 dual-label systems for single-molecule and single-cell translation imaging; establishes fluorescent microscopy as primary modality for visualising protein synthesis in vivo",
      "originalSection": "Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription",
      "metadataStatus": "metadata-matched",
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      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "ref": "NPL-198",
      "recordId": "hsi-0d33d222d235dd",
      "sourceType": "Journal publication",
      "title": "Watching gene expression in color.",
      "authors": "Simpson JH.",
      "year": 2019,
      "journal": "eLife",
      "doi": "10.7554/elife.49414",
      "pmid": "31348001",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Simpson CL (2019). \"Watching Gene Expression in Color: TransTimer Dual-Colour Fluorescent Reporter.\" eLife 8:e49414 — TransTimer reporter system: slow-maturing green fluorescent protein and fast-maturing red fluorescent protein under same promoter; green/red ratio encodes time since transcriptional activation; real-time colour-coded visualisation of transcriptional history in living cells",
      "originalSection": "Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription",
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    {
      "ref": "NPL-199",
      "recordId": "hsi-d9b2c705e7f695",
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      "title": "Introduction to Fluorescent Proteins",
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      "originalCitation": "Piston DW, Campbell RE, Day RN, Davidson MW. \"Introduction to Fluorescent Proteins.\" ZEISS Microscopy Online Campus — Education in Microscopy and Digital Imaging, Carl Zeiss Microscopy (zeiss-campus.magnet.fsu.edu/articles/probes/fpintroduction.html) — Comprehensive tutorial on the structure, spectral properties, brightness, maturation, and oligomerisation of fluorescent proteins derived from Aequorea victoria GFP and Anthozoa reef corals; details the 11-stranded β-barrel scaffold that protects the chromophore; the self-catalysed tripeptide cyclisation and oxidation reaction forming extended π-electron conjugated systems responsible for fluorescence; chromophore engineering via site-directed mutagenesis; fusion chimera design; fluorescent protein reporters and biosensors for monitoring gene expression, protein kinase activity, ion concentration, voltage, and cyclic nucleotide signalling in living cells",
      "originalSection": "Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription",
      "metadataStatus": "documentary-source",
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    {
      "ref": "NPL-200",
      "recordId": "hsi-c72f6f428330c2",
      "sourceType": "Journal publication",
      "title": "Single-molecule analysis of transcription factor binding at transcription sites in live cells.",
      "authors": "Morisaki T, Müller WG, Golob N, Mazza D, McNally JG.",
      "year": 2014,
      "journal": "Nature communications",
      "doi": "10.1038/ncomms5456",
      "pmid": "25034201",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Morisaki T, Müller WG, Golob N, Mazza D, McNally JG (2014). \"Single-molecule analysis of transcription factor binding at transcription sites in live cells.\" Nature Communications 5:4456. DOI: 10.1038/ncomms5456",
      "originalSection": "Fractal TFBS Analysis",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [],
      "topicId": "imaging-transcriptomics",
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    {
      "ref": "NPL-201",
      "recordId": "hsi-ca225cf85be823",
      "sourceType": "Journal publication",
      "title": "The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression.",
      "authors": "Almassalha LM, Tiwari A, Ruhoff PT, Stypula-Cyrus Y, Cherkezyan L, Matsuda H, Dela Cruz MA, Chandler JE, White C, Maneval C, Subramanian H, Szleifer I, Roy HK, Backman V.",
      "year": 2017,
      "journal": "Scientific reports",
      "doi": "10.1038/srep41061",
      "pmid": "28117353",
      "pmcid": "PMC5259786",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Almassalha LM, Silverstein SD, Bauer GM et al. (2017). \"The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression.\" Scientific Reports 7:41061. DOI: 10.1038/srep41061",
      "originalSection": "Fractal TFBS Analysis",
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    {
      "ref": "NPL-202",
      "recordId": "hsi-640ffd898d4f0f",
      "sourceType": "Journal publication",
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      "authors": "Xie Z, Sokolov I, Osmala M, Yue X, Bower G, Pett JP, Chen Y, Wang K, Cavga AD, Popov A, Teichmann SA, Morgunova E, Kvon EZ, Yin Y, Taipale J.",
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        "Publication notice: Erratum in; 40461788"
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      "authors": "Taylor SJ, Stauber J, Bohorquez O, Tatsumi G, Kumari R, Chakraborty J, Bartholdy BA, Schwenger E, Sundaravel S, Farahat AA, Wheat JC, Goldfinger M, Verma A, Kumar A, Boykin DW, Stengel KR, Poon GMK, Steidl U.",
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      "originalCitation": "Taylor SJ, Stauber J, Bohorquez O et al. (2024). \"Pharmacological restriction of genomic binding sites redirects PU.1 pioneer transcription factor activity.\" Nature Genetics 56:2213–2227. DOI: 10.1038/s41588-024-01911-7",
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      "sourceType": "Journal publication",
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      "authors": "Duttke SH, Guzman C, Chang M, Delos Santos NP, McDonald BR, Xie J, Carlin AF, Heinz S, Benner C.",
      "year": 2024,
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      "originalCitation": "Duttke SH, Guzman C, Chang M et al. (2024). \"Position-dependent function of human sequence-specific transcription factors.\" Nature 631:891–898. DOI: 10.1038/s41586-024-07662-z",
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      "sourceType": "Journal publication",
      "title": "Modeling and designing enhancers by introducing and harnessing transcription factor binding units.",
      "authors": "Li J, Zhang P, Xi X, Liu L, Wei L, Wang X.",
      "year": 2025,
      "journal": "Nature communications",
      "doi": "10.1038/s41467-025-56749-2",
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      "originalCitation": "Li J, Zhang P, Xi X, Liu L, Wei L, Wang X (2025). \"Modeling and designing enhancers by introducing and harnessing transcription factor binding units.\" Nature Communications 16:1469. DOI: 10.1038/s41467-025-56749-2",
      "originalSection": "Fractal TFBS Analysis",
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      "ref": "NPL-206",
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      "year": 2018,
      "journal": "Nature communications",
      "doi": "10.1038/s41467-018-04130-x",
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      "originalCitation": "Cortini R, Filion GJ (2018). \"Theoretical principles of transcription factor traffic on folded chromatin.\" Nature Communications 9:1740. DOI: 10.1038/s41467-018-04130-x",
      "originalSection": "Fractal TFBS Analysis",
      "metadataStatus": "metadata-matched",
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    {
      "ref": "NPL-207",
      "recordId": "hsi-43757b09c98745",
      "sourceType": "Journal publication",
      "title": "Context transcription factors establish cooperative environments and mediate enhancer communication.",
      "authors": "Kribelbauer-Swietek JF, Pushkarev O, Gardeux V, Faltejskova K, Russeil J, van Mierlo G, Deplancke B.",
      "year": 2024,
      "journal": "Nature genetics",
      "doi": "10.1038/s41588-024-01892-7",
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      "originalCitation": "Kribelbauer-Swietek JF, Pushkarev O, Gardeux V, Faltejskova K, Russeil J, van Mierlo G, Deplancke B (2024). \"Context transcription factors establish cooperative environments and mediate enhancer communication.\" Nature Genetics 56:2199–2212. DOI: 10.1038/s41588-024-01892-7",
      "originalSection": "Fractal TFBS Analysis",
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    {
      "ref": "NPL-208",
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      "sourceType": "Journal publication",
      "title": "Positional distribution of transcription factor binding sites in Arabidopsis thaliana.",
      "authors": "Yu CP, Lin JJ, Li WH, Li WH.",
      "year": 2016,
      "journal": "Scientific reports",
      "doi": "10.1038/srep25164",
      "pmid": "27117388",
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      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Yu CP, Lin JJ, Li WH (2016). \"Positional distribution of transcription factor binding sites in Arabidopsis thaliana.\" Scientific Reports 6:25164. DOI: 10.1038/srep25164",
      "originalSection": "Fractal TFBS Analysis",
      "metadataStatus": "metadata-matched",
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    {
      "ref": "NPL-209",
      "recordId": "hsi-ca225cf85be823",
      "sourceType": "Journal publication",
      "title": "The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression.",
      "authors": "Almassalha LM, Tiwari A, Ruhoff PT, Stypula-Cyrus Y, Cherkezyan L, Matsuda H, Dela Cruz MA, Chandler JE, White C, Maneval C, Subramanian H, Szleifer I, Roy HK, Backman V.",
      "year": 2017,
      "journal": "Scientific reports",
      "doi": "10.1038/srep41061",
      "pmid": "28117353",
      "pmcid": "PMC5259786",
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Almassalha LM, Silverstein SD, Bauer GM et al. (2017). \"The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression.\" Scientific Reports 7:41061. DOI: 10.1038/srep41061",
      "originalSection": "Fractal TFBS Analysis",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-210",
      "recordId": "hsi-e0d5c3805210ed",
      "sourceType": "Journal publication",
      "title": "Highly accurate protein structure prediction with AlphaFold.",
      "authors": "Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Žídek A, Potapenko A, Bridgland A, Meyer C, Kohl SAA, Ballard AJ, Cowie A, Romera-Paredes B, Nikolov S, Jain R, Adler J, Back T, Petersen S, Reiman D, Clancy E, Zielinski M, Steinegger M, Pacholska M, Berghammer T, Bodenstein S, Silver D, Vinyals O, Senior AW, Kavukcuoglu K, Kohli P, Hassabis D.",
      "year": 2021,
      "journal": "Nature",
      "doi": "10.1038/s41586-021-03819-2",
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      "patentNumber": null,
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      "originalCitation": "Jumper J, Evans R, Pritzel A et al. (2021). \"Highly accurate protein structure prediction with AlphaFold.\" Nature 596:583–589. DOI: 10.1038/s41586-021-03819-2 — AlphaFold2: atomic-accuracy protein structure prediction from amino acid sequence; won CASP14; 2024 Nobel Prize in Chemistry (Hassabis & Jumper)",
      "originalSection": "AI-Driven Protein Structure Prediction (AlphaFold)",
      "metadataStatus": "metadata-matched",
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      "corrections": [],
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    {
      "ref": "NPL-211",
      "recordId": "hsi-a767ad286ab4ab",
      "sourceType": "Journal publication",
      "title": "AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models.",
      "authors": "Varadi M, Anyango S, Deshpande M, Nair S, Natassia C, Yordanova G, Yuan D, Stroe O, Wood G, Laydon A, Žídek A, Green T, Tunyasuvunakool K, Petersen S, Jumper J, Clancy E, Green R, Vora A, Lutfi M, Figurnov M, Cowie A, Hobbs N, Kohli P, Kleywegt G, Birney E, Hassabis D, Velankar S.",
      "year": 2022,
      "journal": "Nucleic acids research",
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      "originalCitation": "Varadi M, Anyango S, Deshpande M et al. (2022). \"AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models.\" Nucleic Acids Research 50(D1):D439–D444. DOI: 10.1093/nar/gkab1061 — 200M+ predicted protein structures; EMBL-EBI partnership; 3M+ researchers across 190+ countries",
      "originalSection": "AI-Driven Protein Structure Prediction (AlphaFold)",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-212",
      "recordId": "hsi-a69099559ecd76",
      "sourceType": "Journal publication",
      "title": "Accurate structure prediction of biomolecular interactions with AlphaFold 3.",
      "authors": "Abramson J, Adler J, Dunger J, Evans R, Green T, Pritzel A, Ronneberger O, Willmore L, Ballard AJ, Bambrick J, Bodenstein SW, Evans DA, Hung CC, O'Neill M, Reiman D, Tunyasuvunakool K, Wu Z, Žemgulytė A, Arvaniti E, Beattie C, Bertolli O, Bridgland A, Cherepanov A, Congreve M, Cowen-Rivers AI, Cowie A, Figurnov M, Fuchs FB, Gladman H, Jain R, Khan YA, Low CMR, Perlin K, Potapenko A, Savy P, Singh S, Stecula A, Thillaisundaram A, Tong C, Yakneen S, Zhong ED, Zielinski M, Žídek A, Bapst V, Kohli P, Jaderberg M, Hassabis D, Jumper JM.",
      "year": 2024,
      "journal": "Nature",
      "doi": "10.1038/s41586-024-07487-w",
      "pmid": "38718835",
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      "patentNumber": null,
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      "originalCitation": "Abramson J, Adler J, Dunger J et al. (2024). \"Accurate structure prediction of biomolecular interactions with AlphaFold 3.\" Nature 630:493–500. DOI: 10.1038/s41586-024-07487-w — Protein–DNA, protein–RNA, protein–ligand, and protein–ion complex structure prediction; ≥50% accuracy improvement over existing methods",
      "originalSection": "AI-Driven Protein Structure Prediction (AlphaFold)",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-213",
      "recordId": "hsi-adeb0509f25117",
      "sourceType": "Journal publication",
      "title": "Accurate proteome-wide missense variant effect prediction with AlphaMissense.",
      "authors": "Cheng J, Novati G, Pan J, Bycroft C, Žemgulytė A, Applebaum T, Pritzel A, Wong LH, Zielinski M, Sargeant T, Schneider RG, Senior AW, Jumper J, Hassabis D, Kohli P, Avsec Ž.",
      "year": 2023,
      "journal": "Science (New York, N.Y.)",
      "doi": "10.1126/science.adg7492",
      "pmid": "37733863",
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      "originalAssignee": null,
      "originalCitation": "Cheng J, Novati G, Pan J et al. (2023). \"Accurate proteome-wide missense variant effect prediction with AlphaMissense.\" Science 381(6664):eadg7492. DOI: 10.1126/science.adg7492 — 71 million missense variants classified across human proteome; 89% categorised as likely benign or likely pathogenic",
      "originalSection": "AI-Driven Protein Structure Prediction (AlphaFold)",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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    {
      "ref": "NPL-214",
      "recordId": "hsi-7ad76f3461e8f4",
      "sourceType": "Preprint",
      "title": "Integration of hyperspectral imaging and transcriptomics from individual cells with HyperSeq",
      "authors": "Xie Y, Habibalahi A, Anwer AG, Wahi K, Gatt C, Johansson EMV, Holst J, Goldys E, Zanini F.",
      "year": 2024,
      "journal": "",
      "doi": "10.1101/2024.01.27.577536",
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      "originalCitation": "Xie Y, Habibalahi A, Zanini F, Vukovic M, Nassiri R, Wang X, Cao Y, Anttila CJ, Dehkhoda F, Goldys EM, Tian L (2024). \"Integration of hyperspectral imaging and transcriptomics from individual cells with HyperSeq.\" bioRxiv preprint. DOI: 10.1101/2024.01.27.577536 — Combines hyperspectral autofluorescence imaging with scRNA-seq in MCF-7 breast cancer cells; correlates cellular optical signatures with gene expression profiles at single-cell resolution; provides ground-truth data linking autofluorescence molecular signatures to TFBS activity",
      "originalSection": "Fractal TFBS Analysis / Fractal Chromatin 3D Organisation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://doi.org/10.1101/2024.01.27.577536",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.1101%2F2024.01.27.577536%22&format=json&resultType=core&pageSize=4",
      "corrections": [],
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      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-215",
      "recordId": "hsi-33295070309002",
      "sourceType": "Journal publication",
      "title": "Fractal dimension of time-resolved autofluorescence discriminates tumour from healthy tissues in the oral cavity.",
      "authors": "Klatt J, Gerich CE, Gröbe A, Opitz J, Schreiber J, Hanken H, Salomon G, Heiland M, Kluwe L, Blessmann M.",
      "year": 2014,
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      "doi": "10.1016/j.jcms.2013.12.004",
      "pmid": "24444757",
      "pmcid": null,
      "patentNumber": null,
      "originalAssignee": null,
      "originalCitation": "Klatt J, Gerich CE, Gröbe A, Opitz J, Horlitz F, Hanken H, Schwarz RA, Gilon A et al. (2014). \"Fractal dimension of time-resolved autofluorescence discriminates tumour from healthy tissues in the oral cavity.\" Journal of Cranio-Maxillo-Facial Surgery 42(6):852–854. PMID: 24444757 — Fractal D of tumour = 1.8 vs healthy = 1.6; 100% sensitivity, 86% specificity, AUC 99%; demonstrates fractal autofluorescence analysis as a tissue-state discriminator",
      "originalSection": "Fractal TFBS Analysis / Fractal Chromatin 3D Organisation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
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      "corrections": [],
      "topicId": "autofluorescence-sensing",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-216",
      "recordId": "hsi-d4f9970183960d",
      "sourceType": "Journal publication",
      "title": "Spatial distribution of predicted transcription factor binding sites in Drosophila ChIP peaks.",
      "authors": "Pettie KP, Dresch JM, Drewell RA.",
      "year": 2016,
      "journal": "Mechanisms of development",
      "doi": "10.1016/j.mod.2016.06.001",
      "pmid": "27264535",
      "pmcid": "PMC5441388",
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      "originalAssignee": null,
      "originalCitation": "Pettie KP, Dresch JM, Drewell RA (2016). \"Spatial distribution of predicted transcription factor binding sites in Drosophila ChIP peaks.\" Mechanisms of Development 141:51–61. PMC5441388 — TFBS broadly distributed across ChIP peaks rather than narrowly centred; multiple sites per peak; establishes that TFBS positional distribution within regulatory regions carries functional significance",
      "originalSection": "Fractal TFBS Analysis / Fractal Chromatin 3D Organisation",
      "metadataStatus": "metadata-matched",
      "claimReview": "Not independently appraised",
      "sourceURL": "https://www.notion.so/3807b9c99c5680599be7d8337c817b15",
      "publicationURL": "https://pubmed.ncbi.nlm.nih.gov/27264535/",
      "metadataURL": "https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID%3APMC5441388&format=json&resultType=core&pageSize=4",
      "corrections": [],
      "topicId": "imaging-transcriptomics",
      "role": "Focused chapter source"
    },
    {
      "ref": "NPL-217",
      "recordId": "hsi-49e12e857b5371",
      "sourceType": "Journal publication",
      "title": "Transcription factor binding sites and other features in human and Drosophila proximal promoters.",
      "authors": "Vinson C, Chatterjee R, Fitzgerald P.",
      "year": 2011,
      "journal": "Sub-cellular biochemistry",
      "doi": "10.1007/978-90-481-9069-0_10",
      "pmid": "21557085",
      "pmcid": "PMC7394279",
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      "reportedApplication": "Agriculture, forensics",
      "sourceReferences": [
        "NPL-154",
        "NPL-155"
      ],
      "recordId": "hsi-852a0ba2dbf56c",
      "status": "Historical source description; capability appraisal pending"
    },
    {
      "sourceOrder": 6,
      "year": "2017",
      "entity": "Changhong / Consumer Physics",
      "technologyClass": "Embedded NIR spectroscopy",
      "description": "Changhong H2: first smartphone with embedded NIR sensor",
      "reportedSpectralBand": "NIR ~700–1100 nm",
      "reportedApplication": "Consumer molecular sensing",
      "sourceReferences": [
        "NPL-147"
      ],
      "recordId": "hsi-2d7983e4ef049a",
      "status": "Historical source description; capability appraisal pending"
    },
    {
      "sourceOrder": 7,
      "year": "2017",
      "entity": "Apple / STMicroelectronics",
      "technologyClass": "NIR depth sensing",
      "description": "TrueDepth dedicated NIR camera + IR dot projector",
      "reportedSpectralBand": "NIR ~940 nm",
      "reportedApplication": "Face ID geometric authentication",
      "sourceReferences": [
        "NPL-148"
      ],
      "recordId": "hsi-e3944b33936175",
      "status": "Historical source description; capability appraisal pending"
    },
    {
      "sourceOrder": 8,
      "year": "2021",
      "entity": "Stuart et al.",
      "technologyClass": "Smartphone HSI attachment",
      "description": "3D-printed smartphone HSI attachment (£100)",
      "reportedSpectralBand": "Vis–NIR",
      "reportedApplication": "Environmental / geoscience",
      "sourceReferences": [
        "NPL-150"
      ],
      "recordId": "hsi-92cd98c0974786",
      "status": "Historical source description; capability appraisal pending"
    },
    {
      "sourceOrder": 12,
      "year": "2023",
      "entity": "Yang et al. / Hitspectra (Taiwan)",
      "technologyClass": "Endoscopic reconstruction",
      "description": "SAVE HSI engine + CycleGAN narrowband simulation on standard RGB endoscope",
      "reportedSpectralBand": "Vis–NIR (software reconstruction)",
      "reportedApplication": "Early esophageal cancer inference",
      "sourceReferences": [
        "NPL-221"
      ],
      "recordId": "hsi-30eaacfb450209",
      "status": "Historical source description; capability appraisal pending",
      "correctionNote": "The study compares image-quality measures. Prospective clinical diagnostic accuracy is not established by those comparisons alone."
    },
    {
      "sourceOrder": 9,
      "year": "2024",
      "entity": "Stuart et al.",
      "technologyClass": "Field imaging",
      "description": "Field-deployed smartphone HSI (Greenland)",
      "reportedSpectralBand": "Vis–NIR",
      "reportedApplication": "Environmental monitoring",
      "sourceReferences": [
        "NPL-151"
      ],
      "recordId": "hsi-a911e8605e024c",
      "status": "Historical source description; capability appraisal pending"
    },
    {
      "sourceOrder": 10,
      "year": "2024",
      "entity": "Meng et al.",
      "technologyClass": "Laboratory infrared HSI",
      "description": "CQD infrared HSI with single-pixel inference",
      "reportedSpectralBand": "SWIR 1050–1630 nm",
      "reportedApplication": "Laboratory imaging",
      "sourceReferences": [
        "NPL-152"
      ],
      "recordId": "hsi-c2365ea769851d",
      "status": "Historical source description; capability appraisal pending"
    },
    {
      "sourceOrder": 11,
      "year": "2025",
      "entity": "Kwon & Kim (Purdue)",
      "technologyClass": "RGB spectral reconstruction",
      "description": "Spectral colour-chart and computational reconstruction from RGB photographs",
      "reportedSpectralBand": "Vis–NIR (software)",
      "reportedApplication": "Tissue oximetry, blood haemoglobin",
      "sourceReferences": [
        "NPL-1",
        "NPL-153"
      ],
      "recordId": "hsi-fda6f081ed5bea",
      "status": "Method and wavelength range checked against the primary article; application claims need separate sources.",
      "spectralBand": "Visible 400–720 nm",
      "correctionNote": "The original timeline labels this Vis–NIR. The cited study describes visible-range reconstruction using a physical reference chart; the original band and application wording are retained as source claims."
    },
    {
      "sourceOrder": 13,
      "year": "2016–present",
      "entity": "Hitspectra Intelligent Technology (Taiwan)",
      "technologyClass": "Commercial medical imaging",
      "description": "HSI integration with standard medical lenses (dermatoscope, ophthalmoscope, odontoscope)",
      "reportedSpectralBand": "Vis–NIR (400+ channels per pixel)",
      "reportedApplication": "Skin disease (85%), retinal disease, oral cancer staging",
      "sourceReferences": [
        "NPL-222"
      ],
      "recordId": "hsi-33a52b5cee68bb",
      "status": "Historical source description; capability appraisal pending"
    }
  ],
  "publicationVersions": [
    {
      "ref": "NPL-9",
      "recordId": "hsi-7ad76f3461e8f4"
    },
    {
      "ref": "NPL-9b",
      "recordId": "hsi-6fe5f46314bf49"
    },
    {
      "ref": "NPL-214",
      "recordId": "hsi-7ad76f3461e8f4"
    }
  ]
}