[{"pmid":"42648552","title":"Associations between human oxytocin receptor gene promoter DNA methylation and brain structural connectome in panic disorder in Korea.","doi":"10.1016/j.jad.2026.122425","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/42648552"},{"pmid":"40604321","title":"The interplay between oxytocin receptor and YAP in regulating gastric cancer progression.","doi":"10.1038/s41388-025-03480-3","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40604321"},{"pmid":"42621223","title":"The oxytocinergic system in functional neurological disorder: Preliminary testing of associations with interoception and childhood trauma.","doi":"10.1016/j.cpnec.2026.100376","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/42621223"},{"pmid":"40122503","title":"Oxytocin receptor enhances adipocyte browning and energy metabolism in mice.","doi":"10.1016/j.yexcr.2025.114534","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40122503"},{"pmid":"35688807","title":"Distinct promoter regions of the oxytocin receptor gene are hypomethylated in Prader-Willi syndrome and in Prader-Willi syndrome associated psychosis.","doi":"10.1038/s41398-022-02014-9","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/35688807"},{"pmid":"40658054","title":"The Role of Oxytocin and Oxytocin Gene Receptor Methylation During Withdrawal Therapy in Males With Alcohol Use Disorder.","doi":"10.1111/adb.70060","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40658054"},{"pmid":"PPR432499","title":"Distinct promoter regions of the oxytocin receptor gene are hypomethylated in Prader-Willi syndrome and in Prader-Willi syndrome associated psychosis","doi":"10.1101/2021.12.14.21267765","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR432499"},{"pmid":"37611819","title":"Estrogen regulates the transcription of guppy isotocin receptors.","doi":"10.1016/j.cbpb.2023.110895","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/37611819"},{"pmid":"40790923","title":"Neonatal Procedural Pain Disrupts Phosphorylation of KCC2 in the Spinal Cord.","doi":"10.1002/dneu.22993","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40790923"},{"pmid":"37705612","title":"Transcriptional diversity of the oxytocin receptor in prairie voles: mechanistic implications for behavioral neuroscience and maternal physiology.","doi":"10.3389/fgene.2023.1225197","year":"2023","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/37705612"},{"pmid":"35672748","title":"Oxytocin receptor gene methylation as a molecular marker for severity of depressive symptoms in affective disorder patients.","doi":"10.1186/s12888-022-04031-w","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/35672748"},{"pmid":"PPR429129","title":"Oxytocin Receptor Gene Methylation as a Molecular Marker for Severity of Depressive Symptoms in Affective Disorder Patients","doi":"10.21203/rs.3.rs-1115325/v1","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR429129"},{"pmid":"39002450","title":"Epigenetic regulation of the oxytocin system as an indicator of adaptation to over-controlling parenting and psychosocial functioning in adulthood.","doi":"10.1016/j.psyneuen.2024.107123","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/39002450"},{"pmid":"38409080","title":"Selective alterations of endocannabinoid system genes expression in obsessive compulsive disorder.","doi":"10.1038/s41398-024-02829-8","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/38409080"},{"pmid":"38185116","title":"Methylation of the Oxytocin, Oxytocin Receptor, and Vasopressin Gene Promoters in Tobacco Use Disorder during Cessation.","doi":"10.1159/000535663","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/38185116"},{"pmid":"30950195","title":"DNA methylation-reprogrammed oxytocin receptor underlies insensitivity to oxytocin in pre-eclamptic placental vasculature.","doi":"10.1111/jcmm.14299","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30950195"},{"pmid":"33633538","title":"Maternal Diabetes-Induced Suppression of Oxytocin Receptor Contributes to Social Deficits in Offspring.","doi":"10.3389/fnins.2021.634781","year":"2021","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/33633538"},{"pmid":"41836349","title":"Impaired PIEZO1 function drives uterine hypercontractility in adenomyosis-associated dysmenorrhea.","doi":"10.1093/hropen/hoag013","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/41836349"},{"pmid":"33810239","title":"In Vivo Electrophysiology of Peptidergic Neurons in Deep Layers of the Lumbar Spinal Cord after Optogenetic Stimulation of Hypothalamic Paraventricular Oxytocin Neurons in Rats.","doi":"10.3390/ijms22073400","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/33810239"},{"pmid":"28445928","title":"Regulation of angiogenic behaviors by oxytocin receptor through Gli1-indcued transcription of HIF-1α in human umbilical vein endothelial cells.","doi":"10.1016/j.biopha.2017.04.021","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/28445928"},{"pmid":"32477273","title":"The Role of Glucocorticoid Receptor and Oxytocin Receptor in the Septic Heart in a Clinically Relevant, Resuscitated Porcine Model With Underlying Atherosclerosis.","doi":"10.3389/fendo.2020.00299","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32477273"},{"pmid":"38979623","title":"Genetic Variation and Stroke Recovery: The STRONG Study.","doi":"10.1161/strokeaha.124.047643","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/38979623"},{"pmid":"23441222","title":"DNA methylation of specific CpG sites in the promoter region regulates the transcription of the mouse oxytocin receptor.","doi":"10.1371/journal.pone.0056869","year":"2013","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/23441222"},{"pmid":"32322239","title":"Anxiolytic and Anxiogenic? How the Transcription Factor MEF2 Might Explain the Manifold Behavioral Effects of Oxytocin.","doi":"10.3389/fendo.2020.00186","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32322239"},{"pmid":"33516250","title":"Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression.","doi":"10.1186/s13148-021-01017-5","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/33516250"},{"pmid":"27309964","title":"The altered promoter methylation of oxytocin receptor gene in autism.","doi":"10.1080/01677063.2016.1202951","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27309964"},{"pmid":"26338335","title":"Oxytocin Regulates Stress-Induced Crf Gene Transcription through CREB-Regulated Transcription Coactivator 3.","doi":"10.1523/jneurosci.1345-14.2015","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26338335"},{"pmid":"28785027","title":"Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness.","doi":"10.1038/s41598-017-07950-x","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/28785027"},{"pmid":"27421662","title":"Functional characterization of an oxytocin receptor gene variant (rs2268498) previously associated with social cognition by expression analysis in vitro and in human brain biopsy.","doi":"10.1080/17470919.2016.1214174","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27421662"},{"pmid":"30257007","title":"DNA methylation of OXTR is associated with parasympathetic nervous system activity and amygdala morphology.","doi":"10.1093/scan/nsy086","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30257007"},{"pmid":"27693608","title":"Fibroblast growth factor 2 alters the oxytocin receptor in a developmental model of anxiety-like behavior in male rat pups.","doi":"10.1016/j.yhbeh.2016.09.009","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27693608"},{"pmid":"25677455","title":"Raphe serotonin neuron-specific oxytocin receptor knockout reduces aggression without affecting anxiety-like behavior in male mice only.","doi":"10.1111/gbb.12202","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25677455"},{"pmid":"29513137","title":"Epigenetic modification of the oxytocin and glucocorticoid receptor genes is linked to attachment avoidance in young adults.","doi":"10.1080/14616734.2018.1446451","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29513137"},{"pmid":"27323309","title":"Methylation of the oxytocin receptor gene mediates the effect of adversity on negative schemas and depression.","doi":"10.1017/s0954579416000420","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27323309"},{"pmid":"34371296","title":"Genetic markers of the stress generation model: A systematic review.","doi":"10.1016/j.psychres.2021.114139","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34371296"},{"pmid":"26299644","title":"Chimpanzee sociability is associated with vasopressin (Avpr1a) but not oxytocin receptor gene (OXTR) variation.","doi":"10.1016/j.yhbeh.2015.08.006","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26299644"},{"pmid":"26586210","title":"The oxytocin receptor antagonist, Atosiban, activates pro-inflammatory pathways in human amnion via G(αi) signalling.","doi":"10.1016/j.mce.2015.11.012","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26586210"},{"pmid":"33726803","title":"Intranasal oxytocin administration ameliorates social behavioral deficits in a POGZ<sup>WT/Q1038R</sup> mouse model of autism spectrum disorder.","doi":"10.1186/s13041-021-00769-8","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/33726803"},{"pmid":"PMC8090656","title":"The Circadian Clock Gene Bmal1 Modulates Myometrium Contractile Function in Pregnant Mice","doi":null,"year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PMC/PMC8090656"},{"pmid":"25264479","title":"Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome.","doi":"10.1186/2040-2392-5-48","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25264479"},{"pmid":"32673938","title":"Targeted bisulfite sequencing: A novel tool for the assessment of DNA methylation with high sensitivity and increased coverage.","doi":"10.1016/j.psyneuen.2020.104784","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32673938"},{"pmid":"29858823","title":"Evidence for Association Between OXTR Gene and ASD Clinical Phenotypes.","doi":"10.1007/s12031-018-1088-0","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29858823"},{"pmid":"PPR158470","title":"Targeted bisulfite sequencing: A novel tool for the assessment of DNA methylation with high sensitivity and increased coverage","doi":"10.1101/2020.05.05.078386","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR158470"},{"pmid":"25968600","title":"Signatures of positive selection in the cis-regulatory sequences of the human oxytocin receptor (OXTR) and arginine vasopressin receptor 1a (AVPR1A) genes.","doi":"10.1186/s12862-015-0372-7","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25968600"},{"pmid":"32435727","title":"Epigenetic Modification of <i>OXTR</i> is Associated with Openness to Experience.","doi":"10.1017/pen.2018.7","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32435727"},{"pmid":"32604796","title":"Muscle Cell Morphogenesis, Structure, Development and Differentiation Processes Are Significantly Regulated during Human Ovarian Granulosa Cells In Vitro Cultivation.","doi":"10.3390/jcm9062006","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32604796"},{"pmid":"30682715","title":"Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro.","doi":"10.1016/j.archoralbio.2019.01.007","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30682715"},{"pmid":"30618574","title":"Feasibility of Linking Molecular Genetic Markers to Real-World Social Network Size Tracked on Smartphones.","doi":"10.3389/fnins.2018.00945","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30618574"},{"pmid":"21734268","title":"Synergistic regulation of human oxytocin receptor promoter by CCAAT/ enhancer-binding protein and RELA.","doi":"10.1095/biolreprod.111.092304","year":"2011","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/21734268"},{"pmid":"30628715","title":"'Heart development and morphogenesis' is a novel pathway for human ovarian granulosa cell differentiation during long‑term in vitro cultivation‑a microarray approach.","doi":"10.3892/mmr.2019.9837","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30628715"},{"pmid":"25890851","title":"Methylation of the oxytocin receptor gene in clinically depressed patients compared to controls: The role of OXTR rs53576 genotype.","doi":"10.1016/j.jpsychires.2015.03.012","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25890851"},{"pmid":"30089682","title":"OXTR overexpression leads to abnormal mammary gland development in mice.","doi":"10.1530/joe-18-0356","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30089682"},{"pmid":"30650536","title":"Maternal High Fat Diet-Induced Obesity Modifies Histone Binding and Expression of <i>Oxtr</i> in Offspring Hippocampus in a Sex-Specific Manner.","doi":"10.3390/ijms20020329","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30650536"},{"pmid":"23734094","title":"Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience.","doi":"10.3389/fnins.2013.00083","year":"2013","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/23734094"},{"pmid":"24275011","title":"Brain region-specific methylation in the promoter of the murine oxytocin receptor gene is involved in its expression regulation.","doi":"10.1016/j.psyneuen.2013.10.004","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/24275011"},{"pmid":"21419193","title":"Distribution and identity of neurons expressing the oxytocin receptor in the mouse spinal cord.","doi":"10.1016/j.neulet.2011.03.033","year":"2011","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/21419193"},{"pmid":"26273428","title":"Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex.","doi":"10.1186/s13229-015-0040-1","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26273428"},{"pmid":"29027364","title":"A functional polymorphism of the OXTR gene is associated with autistic traits in Caucasian and Asian populations.","doi":"10.1002/ajmg.b.32596","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29027364"},{"pmid":"28443051","title":"Social Behavior of Pet Dogs Is Associated with Peripheral OXTR Methylation.","doi":"10.3389/fpsyg.2017.00549","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/28443051"},{"pmid":"16569740","title":"Regulation of the human oxytocin receptor by nuclear factor-kappaB and CCAAT/enhancer-binding protein-beta.","doi":"10.1210/jc.2005-2649","year":"2006","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/16569740"},{"pmid":"24071915","title":"An interaction between oxytocin and a genetic variation of the oxytocin receptor modulates amygdala activity toward direct gaze: evidence from a pharmacological imaging genetics study.","doi":"10.1007/s00406-013-0452-x","year":"2013","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/24071915"},{"pmid":"24890751","title":"Anti-inflammatory prostaglandins for the prevention of preterm labour.","doi":"10.1530/rep-13-0587","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/24890751"},{"pmid":"26506050","title":"Genetic modulation of oxytocin sensitivity: a pharmacogenetic approach.","doi":"10.1038/tp.2015.163","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26506050"},{"pmid":"25791982","title":"Impact of Thyroid Hormones on Estrogen Receptor α-Dependent Transcriptional Mechanisms in Ventromedial Hypothalamus and Preoptic Area.","doi":"10.1159/000381459","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25791982"},{"pmid":"24002038","title":"Developmental timing of the effects of maternal care on gene expression and epigenetic regulation of hormone receptor levels in female rats.","doi":"10.1210/en.2013-1595","year":"2013","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/24002038"},{"pmid":"22296985","title":"Ignorance is no excuse: moral judgments are influenced by a genetic variation on the oxytocin receptor gene.","doi":"10.1016/j.bandc.2012.01.003","year":"2012","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/22296985"},{"pmid":"16549056","title":"The novel human gene MIP functions as a co-activator of hMafF.","doi":"10.1016/j.abb.2006.02.011","year":"2006","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/16549056"},{"pmid":"25939854","title":"Circadian clock regulation of melatonin MTNR1B receptor expression in human myometrial smooth muscle cells.","doi":"10.1093/molehr/gav023","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25939854"},{"pmid":"29802896","title":"Cardiac-Specific Overexpression of Oxytocin Receptor Leads to Cardiomyopathy in Mice.","doi":"10.1016/j.cardfail.2018.05.004","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29802896"},{"pmid":"19461999","title":"The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task.","doi":"10.1371/journal.pone.0005535","year":"2009","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/19461999"},{"pmid":"12683935","title":"Molecular regulation of the oxytocin receptor in peripheral organs.","doi":"10.1677/jme.0.0300109","year":"2003","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/12683935"},{"pmid":"26671185","title":"Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells.","doi":"10.1210/en.2015-1784","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26671185"},{"pmid":"26442453","title":"Generation of Oxtr cDNA(HA)-Ires-Cre Mice for Gene Expression in an Oxytocin Receptor Specific Manner.","doi":"10.1002/jcb.25393","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26442453"},{"pmid":"16888077","title":"Interleukin-1-induced NF-kappaB recruitment to the oxytocin receptor gene inhibits RNA polymerase II-promoter interactions in cultured human myometrial cells.","doi":"10.1093/molehr/gal067","year":"2006","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/16888077"},{"pmid":"23927378","title":"Early histone modifications in the ventromedial hypothalamus and preoptic area following oestradiol administration.","doi":"10.1111/jne.12085","year":"2013","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/23927378"},{"pmid":"23533356","title":"Genome-wide analysis of DNA methylation in human amnion.","doi":"10.1155/2013/678156","year":"2013","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/23533356"},{"pmid":"16254027","title":"Estrogen regulates transcription of the ovine oxytocin receptor gene through GC-rich SP1 promoter elements.","doi":"10.1210/en.2005-1120","year":"2006","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/16254027"},{"pmid":"23489762","title":"On the genetic basis of face cognition and its relation to fluid cognitive abilities.","doi":"10.1111/gbb.12034","year":"2013","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/23489762"},{"pmid":"24198165","title":"Oxytocin modulates markers of the unfolded protein response in Caco2BB gut cells.","doi":"10.1007/s12192-013-0473-4","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/24198165"},{"pmid":"24059811","title":"Methylation of the oxytocin receptor gene and oxytocin blood levels in the development of psychopathy.","doi":"10.1017/s0954579413000497","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/24059811"},{"pmid":"25405348","title":"Oxytocin and vasopressin receptor gene variation as a proximate base for inter- and intraspecific behavioral differences in bonobos and chimpanzees.","doi":"10.1371/journal.pone.0113364","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25405348"},{"pmid":"15494465","title":"Mechanical stretch up-regulates the human oxytocin receptor in primary human uterine myocytes.","doi":"10.1210/jc.2004-0277","year":"2005","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/15494465"},{"pmid":"12436925","title":"Cholesterol and steroid hormones: modulators of oxytocin receptor function.","doi":"10.1016/s0079-6123(02)39006-x","year":"2002","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/12436925"},{"pmid":"18356275","title":"A conditional knockout mouse line of the oxytocin receptor.","doi":"10.1210/en.2007-1710","year":"2008","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/18356275"},{"pmid":"19943975","title":"Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms.","doi":"10.1186/1471-230x-9-90","year":"2009","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/19943975"},{"pmid":"21980491","title":"Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats.","doi":"10.1371/journal.pone.0025565","year":"2011","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/21980491"},{"pmid":"17348037","title":"Stretch and interleukin 1 beta: pro-labour factors with similar mitogen-activated protein kinase effects but differential patterns of transcription factor activation and gene expression.","doi":"10.1002/jcp.21019","year":"2007","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/17348037"},{"pmid":"10026817","title":"The molecular basis of oxytocin and oxytocin receptor gene expression in reproductive tissues.","doi":"10.1007/978-1-4615-4871-3_37","year":"1998","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10026817"},{"pmid":"18655873","title":"Behavioural studies using temporal and spatial inactivation of the oxytocin receptor.","doi":"10.1016/s0079-6123(08)00407-x","year":"2008","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/18655873"},{"pmid":"8910808","title":"Species differences in central oxytocin receptor gene expression: comparative analysis of promoter sequences.","doi":"10.1046/j.1365-2826.1996.05188.x","year":"1996","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/8910808"},{"pmid":"11694763","title":"Differential interaction of estrogen receptor and thyroid hormone receptor isoforms on the rat oxytocin receptor promoter leads to differences in transcriptional regulation.","doi":"10.1159/000054698","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11694763"},{"pmid":"22485186","title":"Nuclear factor kappa B activation occurs in the amnion prior to labour onset and modulates the expression of numerous labour associated genes.","doi":"10.1371/journal.pone.0034707","year":"2012","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/22485186"},{"pmid":"10527846","title":"Molecular cloning of a human MafF homologue, which specifically binds to the oxytocin receptor gene in term myometrium.","doi":"10.1006/bbrc.1999.1487","year":"1999","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/10527846"},{"pmid":"9579693","title":"Estrogen receptor alpha is essential for induction of oxytocin receptor by estrogen.","doi":"10.1097/00001756-199803300-00031","year":"1998","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/9579693"},{"pmid":"21079000","title":"miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.","doi":"10.1073/pnas.1008301107","year":"2010","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/21079000"},{"pmid":"9228295","title":"Interferon tau: a novel pregnancy recognition signal.","doi":"10.1111/j.1600-0897.1997.tb00253.x","year":"1997","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/9228295"},{"pmid":"10027615","title":"Regulation of the human oxytocin receptor in the uterus: a molecular approach.","doi":"10.1093/humupd/4.5.615","year":"1998","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10027615"},{"pmid":"17043644","title":"Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.","doi":"10.1038/sj.onc.1210041","year":"2007","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/17043644"},{"pmid":"9048622","title":"Cloning, novel promoter sequence, and estrogen regulation of a rat oxytocin receptor gene.","doi":"10.1210/endo.138.3.4998","year":"1997","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/9048622"},{"pmid":"11392025","title":"Progesterone and the progesterone receptor.","doi":null,"year":"1999","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11392025"},{"pmid":"12887422","title":"Viral vector-mediated gene transfer of the vole V1a vasopressin receptor in the rat septum: improved social discrimination and active social behaviour.","doi":"10.1046/j.1460-9568.2003.02750.x","year":"2003","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/12887422"},{"pmid":"9473629","title":"NGF, cyclic AMP, and phorbol esters regulate oxytocin receptor gene transcription in SK-N-SH and MCF7 cells.","doi":"10.1016/s0169-328x(97)00287-8","year":"1998","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/9473629"},{"pmid":"11726201","title":"DNA methylation of the human oxytocin receptor gene promoter regulates tissue-specific gene suppression.","doi":"10.1006/bbrc.2001.6024","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11726201"},{"pmid":"11932306","title":"Characterization and functional analysis of cAMP response element modulator protein and activating transcription factor 2 (ATF2) isoforms in the human myometrium during pregnancy and labor: identification of a novel ATF2 species with potent transactivation properties.","doi":"10.1210/jcem.87.4.8360","year":"2002","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11932306"},{"pmid":"12604656","title":"Transcriptional regulation of the bovine oxytocin receptor gene.","doi":"10.1095/biolreprod.102.008961","year":"2003","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/12604656"},{"pmid":"9213136","title":"Gene targeting approaches to neuroendocrinology: oxytocin, maternal behavior, and affiliation.","doi":"10.1006/hbeh.1997.1377","year":"1997","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/9213136"},{"pmid":"1338957","title":"Trophoblast interferons in early pregnancy of domestic ruminants.","doi":null,"year":"1992","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/1338957"},{"pmid":"9027321","title":"Structure and expression of the mouse oxytocin receptor gene.","doi":"10.1016/s0303-7207(96)03923-8","year":"1996","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/9027321"},{"pmid":"14596857","title":"Mapping oxytocin receptor gene expression in the mouse brain and mammary gland using an oxytocin receptor-LacZ reporter mouse.","doi":"10.1016/s0306-4522(03)00283-5","year":"2003","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/14596857"},{"pmid":"11241181","title":"The effects of lipopolysaccharide and interleukins-1alpha, -2 and -6 on oxytocin receptor expression and prostaglandin production in bovine endometrium.","doi":"10.1677/joe.0.1680497","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11241181"},{"pmid":"11226028","title":"Trophoblast interferon and pregnancy.","doi":"10.1530/rep.0.1210041","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11226028"},{"pmid":"10221779","title":"Differential protein-DNA binding analysis identifies a novel enhancer element, US-1, involved in the upregulation of the oxytocin receptor gene in human myometrium at term.","doi":"10.1016/s0303-7207(98)00225-1","year":"1999","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/10221779"},{"pmid":"10792583","title":"Isolation and characterization of the promoter region of the rat vasopressin V1b receptor gene.","doi":"10.1046/j.1365-2826.2000.00473.x","year":"2000","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10792583"},{"pmid":"10026808","title":"Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation.","doi":"10.1007/978-1-4615-4871-3_28","year":"1998","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10026808"},{"pmid":"18655900","title":"Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between.","doi":"10.1016/s0079-6123(08)00434-2","year":"2008","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/18655900"},{"pmid":"18582926","title":"Dietary n-3 polyunsaturated fatty acids alter the expression of genes involved in prostaglandin biosynthesis in the bovine uterus.","doi":"10.1016/j.theriogenology.2008.05.048","year":"2008","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/18582926"},{"pmid":"7816817","title":"Structure, characterization, and expression of the rat oxytocin receptor gene.","doi":"10.1073/pnas.92.1.200","year":"1995","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/7816817"},{"pmid":"21090345","title":"[Neuropeptide oxytocin and male infertility].","doi":null,"year":"2010","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/21090345"},{"pmid":"21409862","title":"Small scale transcript expression profile of Human first trimester placental villi analyzed by a custom-tailored cDNA array.","doi":null,"year":"2010","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/21409862"},{"pmid":"11250916","title":"Transcriptional regulation of oxytocin receptor by interleukin-1beta and interleukin-6.","doi":"10.1210/endo.142.4.8107","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11250916"},{"pmid":"10218980","title":"Identification of a GABP alpha/beta binding site involved in the induction of oxytocin receptor gene expression in human breast cells, potentiation by c-Fos/c-Jun.","doi":"10.1210/endo.140.5.6710","year":"1999","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/10218980"},{"pmid":"8713994","title":"Gonadal steroid regulation of oxytocin and oxytocin receptor gene expression.","doi":null,"year":"1995","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/8713994"},{"pmid":"11687272","title":"Differential crosstalk between estrogen receptor (ER)alpha and ERbeta and the thyroid hormone receptor isoforms results in flexible regulation of the consensus ERE.","doi":"10.1016/s0169-328x(01)00165-6","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11687272"},{"pmid":"12372009","title":"Isoform specificity for oestrogen receptor and thyroid hormone receptor genes and their interactions on the NR2D gene promoter.","doi":"10.1046/j.1365-2826.2002.00853.x","year":"2002","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/12372009"},{"pmid":"11145571","title":"Interferon-tau activates multiple signal transducer and activator of transcription proteins and has complex effects on interferon-responsive gene transcription in ovine endometrial epithelial cells.","doi":"10.1210/endo.142.1.7891","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11145571"},{"pmid":"8691097","title":"Functional characterisation of an ovine endometrial oxytocin receptor cDNA transiently expressed in Cos-7 cells.","doi":"10.1677/joe.0.1490389","year":"1996","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/8691097"},{"pmid":"7650021","title":"Structure of the rat V1a vasopressin receptor gene and characterization of its promoter region and complete cDNA sequence of the 3'-end.","doi":"10.1074/jbc.270.34.20042","year":"1995","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/7650021"},{"pmid":"11274341","title":"The oxytocin receptor system: structure, function, and regulation.","doi":"10.1152/physrev.2001.81.2.629","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11274341"},{"pmid":"42262468","title":"Genetic Characterization of MAOA and OXTR in Western Lowland Gorillas (Gorilla gorilla gorilla).","doi":"10.1002/ajp.70173","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/42262468"},{"pmid":"40943635","title":"Molecular Insights into Bromocriptine Binding to GPCRs Within Histamine-Linked Signaling Networks: Network Pharmacology, Pharmacophore Modeling, and Molecular Dynamics Simulation.","doi":"10.3390/ijms26178717","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40943635"},{"pmid":"42497930","title":"Luteolin reverses chemoresistance in colorectal cancer cells via TET1/TDG-dependent epigenetic repression of β-catenin.","doi":"10.1016/j.fct.2026.116296","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/42497930"},{"pmid":"PPR1331787","title":"DNA Methylation of Neurodevelopmental, Stress-Response, Reward, and Opioid Pathway Genes: Sex Differences in Infants with Neonatal Opioid Exposure","doi":"10.64898/2026.09.28.26364198","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR1331787"},{"pmid":"41087344","title":"Involvement of the DNA Demethylase Thymine DNA Glycosylase in Anticancer Drug Resistance.","doi":"10.4062/biomolther.2025.143","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/41087344"},{"pmid":"39442277","title":"The alteration in myometrial mRNA transcription of the regulatory genes of DNA methylation in mare with endometrosis.","doi":"10.1016/j.repbio.2024.100962","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/39442277"},{"pmid":"39388927","title":"Modulatory effects of oxytocin on normal human cultured melanocyte proliferation, migration, and melanogenesis.","doi":"10.1016/j.tice.2024.102579","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/39388927"},{"pmid":"35611548","title":"Comparative Study of Autophagy in Oxaliplatin-Sensitive and Resistant SNU-C5 Colon Cancer Cells.","doi":"10.4062/biomolther.2022.028","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/35611548"},{"pmid":"PPR997327","title":"Lentiviral CRISPRa/i in the adult Prairie Vole Brain: Modulating Neuronal Gene Expression Without DNA Cleavage","doi":"10.1101/2025.03.30.646142","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR997327"},{"pmid":"40520467","title":"Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage.","doi":"10.3389/fgeed.2025.1602983","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40520467"},{"pmid":"36094838","title":"HIF-1α is essential for the augmentation of myometrial contractility during labor†.","doi":"10.1093/biolre/ioac174","year":"2022","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/36094838"},{"pmid":"34550578","title":"Measuring Affinity of Ligands to the Oxytocin Receptor Using Radioligand Binding.","doi":"10.1007/978-1-0716-1759-5_14","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34550578"},{"pmid":"38617039","title":"DNA methylation differences in genes associated with human personal disorders and deviant behavior.","doi":"10.3934/neuroscience.2024003","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/38617039"},{"pmid":"31138298","title":"Promoter methylation changes and vascular dysfunction in pre-eclamptic umbilical vein.","doi":"10.1186/s13148-019-0685-2","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31138298"},{"pmid":"29524392","title":"Sodium functions as a negative allosteric modulator of the oxytocin receptor.","doi":"10.1016/j.bbamem.2018.03.003","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29524392"},{"pmid":"30806160","title":"Epigenetic alterations associated with childhood trauma and adult mental health outcomes: A systematic review.","doi":"10.1080/15622975.2019.1583369","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30806160"},{"pmid":"27562397","title":"Progesterone Response Element Variation in the OXTR Promoter Region and Paternal Care in New World Monkeys.","doi":"10.1007/s10519-016-9806-2","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27562397"},{"pmid":"25010721","title":"Thermodynamics of the interaction between oxytocin and its myometrial receptor in sheep: a stepwise binding mechanism.","doi":"10.1016/j.bcp.2014.06.025","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25010721"},{"pmid":"27497665","title":"DNA methylation in a sea lamprey vasotocin receptor gene promoter correlates with tissue- and life-stage-specific mRNA expression.","doi":"10.1016/j.cbpb.2016.07.007","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27497665"},{"pmid":"36001138","title":"Mental health and the effects on methylation of stress-related genes in front-line versus other health care professionals during the second wave of COVID-19 pandemic: an Italian pilot study.","doi":"10.1007/s00406-022-01472-y","year":"2023","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/36001138"},{"pmid":"25687563","title":"Fetal DNA methylation of autism spectrum disorders candidate genes: association with spontaneous preterm birth.","doi":"10.1016/j.ajog.2015.02.011","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25687563"},{"pmid":"22030357","title":"Elevated transcription factor specificity protein 1 in autistic brains alters the expression of autism candidate genes.","doi":"10.1016/j.biopsych.2011.09.020","year":"2012","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/22030357"},{"pmid":"21561435","title":"Cholesterol-induced conformational changes in the oxytocin receptor.","doi":"10.1042/bj20101795","year":"2011","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/21561435"},{"pmid":"28321510","title":"DNA methylation patterns of behavior-related gene promoter regions dissect the gray wolf from domestic dog breeds.","doi":"10.1007/s00438-017-1305-5","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/28321510"},{"pmid":"19439725","title":"Characterization of the cyclic adenosine monophosphate target site in the oxytocin receptor gene in rabbit amnion.","doi":"10.1095/biolreprod.109.077941","year":"2009","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/19439725"},{"pmid":"23356283","title":"Insights into the molecular evolution of oxytocin receptor ligand binding.","doi":"10.1042/bst20120256","year":"2013","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/23356283"},{"pmid":"9388660","title":"Characterization of the human oxytocin receptor ligand binding site.","doi":"10.1042/bst025436s","year":"1997","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/9388660"},{"pmid":"18674552","title":"Progesterone suppresses an oxytocin-stimulated signal pathway in COS-7 cells transfected with the oxytocin receptor.","doi":"10.1016/j.steroids.2008.06.014","year":"2008","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/18674552"},{"pmid":"15713062","title":"Oxytocin-receptor binding: why divalent metals are essential.","doi":"10.1021/ja046042v","year":"2005","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/15713062"},{"pmid":"19845973","title":"Defective oxytocin function: a clue to understanding the cause of autism?","doi":"10.1186/1741-7015-7-63","year":"2009","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/19845973"},{"pmid":"10694212","title":"Pharmacologic characterization of the oxytocin receptor in human uterine smooth muscle cells.","doi":"10.1038/sj.bjp.0702996","year":"2000","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10694212"},{"pmid":"18655883","title":"Oxytocin receptors: ligand binding, signalling and cholesterol dependence.","doi":"10.1016/s0079-6123(08)00417-2","year":"2008","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/18655883"},{"pmid":"11171127","title":"Identification of an extracellular segment of the oxytocin receptor providing agonist-specific binding epitopes.","doi":"10.1042/0264-6021:3540465","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11171127"},{"pmid":"18305227","title":"Delayed parturition and altered myometrial progesterone receptor isoform A expression in mice null for Krüppel-like factor 9.","doi":"10.1095/biolreprod.107.065821","year":"2008","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/18305227"},{"pmid":"7798245","title":"Structural organization of the human oxytocin receptor gene.","doi":"10.1016/s0021-9258(18)31656-9","year":"1994","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/7798245"},{"pmid":"7964291","title":"Characterization and localization of a putative oxytocin receptor in the cervix of the oestrous ewe.","doi":"10.1677/joe.0.1420397","year":"1994","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/7964291"},{"pmid":"2539090","title":"Essential role of magnesium in oxytocin-receptor affinity and ligand specificity.","doi":"10.1042/bj2570611","year":"1989","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/2539090"},{"pmid":"8713980","title":"Identification of agonist binding sites of vasopressin and oxytocin receptors.","doi":null,"year":"1995","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/8713980"},{"pmid":"10026816","title":"Genomic and non-genomic mechanisms of oxytocin receptor regulation.","doi":"10.1007/978-1-4615-4871-3_36","year":"1998","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10026816"},{"pmid":"10579742","title":"Oxytocin receptor binding in rat and human heart.","doi":null,"year":"1999","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10579742"},{"pmid":"1849085","title":"Pharmacological versus binding analysis of receptor systems: how do they interplay? Myometrial cell receptors for oxytocin as a paradigm.","doi":"10.1007/bf01958139","year":"1991","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/1849085"},{"pmid":"8940177","title":"Separate agonist and peptide antagonist binding sites of the oxytocin receptor defined by their transfer into the V2 vasopressin receptor.","doi":"10.1074/jbc.271.49.31593","year":"1996","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/8940177"},{"pmid":"11390027","title":"Muscle layer- and region-dependent distributions of oxytocin receptors in the porcine myometrium.","doi":"10.1016/s0196-9781(01)00402-8","year":"2001","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/11390027"},{"pmid":"227664","title":"Study of oxytocin receptor in human myometrium using highly specific 3H-labeled oxytocin.","doi":"10.1507/endocrj1954.26.515","year":"1979","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/227664"},{"pmid":"2842268","title":"Structural requirements of the oxytocin receptor in rat uterus. Free-Wilson analysis in a series of competitive oxytocin inhibitors.","doi":"10.1111/j.1399-3011.1988.tb00911.x","year":"1988","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/2842268"},{"pmid":"3023377","title":"Binding of oxytocin to uterine cells in vitro. Occurrence of several binding site populations and reidentification of oxytocin receptors.","doi":"10.1016/s0021-9258(19)75988-2","year":"1986","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/3023377"},{"pmid":"41109427","title":"Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes.","doi":"10.1016/j.molmet.2025.102269","year":"2026","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/41109427"},{"pmid":"42736186","title":"Variation in oxytocin receptor DNA methylation in female chickens are associated with age, genetics, laying intensity, and housing conditions.","doi":"10.1016/j.psj.2026.107667","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/42736186"},{"pmid":"41894898","title":"Variation in DNA methylation of the oxytocin gene is associated with prosocial, reward-related, decision-making.","doi":"10.1016/j.psyneuen.2026.107815","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/41894898"},{"pmid":"41608980","title":"Time-of-Day Impacts Uterine Circadian Rhythms and Response to Oxytocin: Comparison of Uterine Function in Melatonin-Deficient C57BL/6 Versus Melatonin Proficient CBA/B6 Hybrid Mice.","doi":"10.1111/jpi.70112","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/41608980"},{"pmid":"40681546","title":"Interplay of plasma Oxytocin and oxytocin receptor gene methylation levels on empathy in older adults.","doi":"10.1038/s41598-025-07353-3","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40681546"},{"pmid":"41719308","title":"Parental behavior, adult attachment, and DNA methylation of the MT2 oxytocin receptor gene region - The moderating role of neuroticism.","doi":"10.1371/journal.pone.0341072","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/41719308"},{"pmid":"41239825","title":"Unraveling the impact of oxytocin receptor gene methylation on stress and inflammation in older adults.","doi":"10.1111/jne.70113","year":"2026","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/41239825"},{"pmid":"PPR941261","title":"Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes","doi":"10.1101/2024.11.16.622460","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR941261"},{"pmid":"PMC12359793","title":"175. EPIGENETIC INSIGHTS INTO SOCIAL COGNITION: SEX-SPECIFIC INFLUENCES OF BDNF AND OXYTOCIN RECEPTOR GENE METHYLATION","doi":null,"year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PMC/PMC12359793"},{"pmid":"40752121","title":"The sex-different effect of oxytocin receptor gene methylation on cerebral gray matter structures and clinical symptoms in Korean patients with panic disorder.","doi":"10.1016/j.jpsychires.2025.07.012","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/40752121"},{"pmid":"PPR902088","title":"Association Between Relational Mobility and DNA Methylation in Oxytocin Receptor Gene: A Social Epigenetic Study","doi":"10.1101/2024.08.27.609977","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR902088"},{"pmid":"39870696","title":"Epigenetic modulation of social cognition: exploring the impact of methylation in brain-derived neurotrophic factor and oxytocin receptor genes across sex.","doi":"10.1038/s41598-025-86770-w","year":"2025","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/39870696"},{"pmid":"37391413","title":"Endogenous oxytocin levels in children with autism: Associations with cortisol levels and oxytocin receptor gene methylation.","doi":"10.1038/s41398-023-02524-0","year":"2023","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/37391413"},{"pmid":"36707542","title":"Oxytocin receptor DNA methylation is associated with exogenous oxytocin needs during parturition and postpartum hemorrhage.","doi":"10.1038/s43856-023-00244-6","year":"2023","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/36707542"},{"pmid":"37778686","title":"Cocaine use disorder effects on blood oxytocin levels and OXTR DNA methylation.","doi":"10.1016/j.neulet.2023.137506","year":"2023","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/37778686"},{"pmid":"38020783","title":"DNA methylation of the oxytocin receptor interacts with age to impact neural response to social stimuli.","doi":"10.3389/fnagi.2023.1252478","year":"2023","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/38020783"},{"pmid":"PPR585846","title":"Endogenous oxytocin levels in children with autism: Associations with cortisol levels and oxytocin receptor gene methylation","doi":"10.1101/2022.12.15.22283521","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR585846"},{"pmid":"38972246","title":"Facing infant cuteness: How nurturing care motivation and oxytocin system gene methylation are associated with responses to baby schema features.","doi":"10.1016/j.yhbeh.2024.105595","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/38972246"},{"pmid":"34731267","title":"Sucrose intake by rats affected by both intraperitoneal oxytocin administration and time of day.","doi":"10.1007/s00213-021-06014-3","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34731267"},{"pmid":"PPR863965","title":"Epigenetic Modulation of Social Cognition: Exploring the Impact of Methylation in Brain-Derived Neurotrophic Factor and Oxytocin Receptor Genes Across Sex","doi":"10.21203/rs.3.rs-4451901/v1","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR863965"},{"pmid":"34550570","title":"Evaluating Methylation of the Oxytocin Receptor Gene and the Oxytocin Intergenic Region.","doi":"10.1007/978-1-0716-1759-5_6","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34550570"},{"pmid":"PPR902827","title":"Blood DNA methylation levels of the oxytocin promoter predict conversion from mild cognitive impairment to dementia in females within a clinical cohort of cognitive complaints","doi":"10.1101/2024.08.28.24312742","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR902827"},{"pmid":"30106994","title":"Oxytocin receptor is regulated by Peg3.","doi":"10.1371/journal.pone.0202476","year":"2018","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/30106994"},{"pmid":"38482889","title":"A dog's life: Early life histories influence methylation of glucocorticoid (NR3C1) and oxytocin (OXTR) receptor genes, cortisol levels, and attachment styles.","doi":"10.1002/dev.22482","year":"2024","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/38482889"},{"pmid":"34650456","title":"The Methylation of Clock Genes in Perinatal Depression: Which Role for Oxytocin?","doi":"10.3389/fpsyt.2021.734825","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34650456"},{"pmid":"36738470","title":"Vasopressin, and not oxytocin, receptor gene methylation is associated with individual differences in receptive joint attention in chimpanzees (Pan troglodytes).","doi":"10.1002/aur.2895","year":"2023","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/36738470"},{"pmid":"35314247","title":"Oxytocin receptor genes moderate BDNF epigenetic methylation by childhood trauma.","doi":"10.1016/j.jad.2022.03.020","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/35314247"},{"pmid":"37479681","title":"The DNA methylation landscape of the human oxytocin receptor gene (OXTR): data-driven clusters and their relation to gene expression and childhood adversity.","doi":"10.1038/s41398-023-02548-6","year":"2023","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/37479681"},{"pmid":"34973541","title":"Oxytocin system gene methylation is associated with empathic responses towards children.","doi":"10.1016/j.psyneuen.2021.105629","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34973541"},{"pmid":"34749758","title":"The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons.","doi":"10.1186/s12974-021-02313-w","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34749758"},{"pmid":"33394241","title":"DNA Methylation of the Oxytocin Receptor Across Neurodevelopmental Disorders.","doi":"10.1007/s10803-020-04792-x","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/33394241"},{"pmid":"PPR469028","title":"The DNA methylation landscape of the human oxytocin receptor gene (  <i>OXTR</i>  ): Recommendations for future research","doi":"10.1101/2022.03.16.484588","year":"2022","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PPR/PPR469028"},{"pmid":"34471100","title":"Associations between childhood maltreatment and DNA methylation of the oxytocin receptor gene in immune cells of mother-newborn dyads.","doi":"10.1038/s41398-021-01546-w","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34471100"},{"pmid":"33609013","title":"Oxytocin prevents cue-induced reinstatement of oxycodone seeking: Involvement of DNA methylation in the hippocampus.","doi":"10.1111/adb.13025","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/33609013"},{"pmid":"32979349","title":"Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques.","doi":"10.1016/j.yhbeh.2020.104856","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32979349"},{"pmid":"34178979","title":"Oxytocin Receptor Exon III Methylation in the Umbilical Cord Blood of Newborns With Prenatal Exposure to Crack Cocaine.","doi":"10.3389/fcell.2021.639287","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/34178979"},{"pmid":"32631409","title":"Reduced DNA methylation of the oxytocin receptor gene is associated with obsessive-compulsive disorder.","doi":"10.1186/s13148-020-00890-w","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32631409"},{"pmid":"32920561","title":"Oxytocin Receptor Gene DNA Methylation: A Biomarker of Treatment Response in Obsessive-Compulsive Disorder?","doi":"10.1159/000509910","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32920561"},{"pmid":"31768943","title":"Relation of Promoter Methylation of the Oxytocin Gene to Stressful Life Events and Depression Severity.","doi":"10.1007/s12031-019-01446-1","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31768943"},{"pmid":"32993882","title":"Methylation of oxytocin related genes and early life trauma together shape the N170 response to human faces.","doi":"10.1016/j.euroneuro.2020.08.008","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32993882"},{"pmid":"29410310","title":"Associations between oxytocin receptor gene (OXTR) methylation, plasma oxytocin, and attachment across adulthood.","doi":"10.1016/j.ijpsycho.2018.01.008","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29410310"},{"pmid":"31071720","title":"Oxytocin receptor DNA methylation and alterations of brain volumes in maltreated children.","doi":"10.1038/s41386-019-0414-8","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31071720"},{"pmid":"31030686","title":"The interaction between oxytocin receptor gene methylation and maternal behavior on children's early theory of mind abilities.","doi":"10.1017/s0954579419000257","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31030686"},{"pmid":"31526808","title":"Reversal of oxycodone conditioned place preference by oxytocin: Promoting global DNA methylation in the hippocampus.","doi":"10.1016/j.neuropharm.2019.107778","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31526808"},{"pmid":"32738668","title":"Relation of promoter methylation of the structural oxytocin gene to critical life events in major depression: A case control study.","doi":"10.1016/j.jad.2020.07.068","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32738668"},{"pmid":"32790448","title":"Pathways linking childhood trauma to rural, unmarried, African American father involvement through oxytocin receptor gene methylation.","doi":"10.1037/dev0000929","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/32790448"},{"pmid":"31735530","title":"Methylation in Syn and Psd95 genes underlie the inhibitory effect of oxytocin on oxycodone-induced conditioned place preference.","doi":"10.1016/j.euroneuro.2019.10.010","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31735530"},{"pmid":"28049625","title":"Regulation of the macrophage oxytocin receptor in response to inflammation.","doi":"10.1152/ajpendo.00346.2016","year":"2017","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/28049625"},{"pmid":"31813807","title":"Methylation of glucocorticoid receptor (NR3C1), BDNF and oxytocin receptor genes in association with childhood maltreatment in schizophrenia and schizoaffective disorder.","doi":"10.1016/j.schres.2019.11.050","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31813807"},{"pmid":"30415783","title":"Oxytocin receptor gene methylation in male and female PTSD patients and trauma-exposed controls.","doi":"10.1016/j.euroneuro.2018.10.006","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30415783"},{"pmid":"27867940","title":"Oxytocin Receptor <i>(OXTR)</i> Methylation and Cognition in Psychotic Disorders.","doi":"10.1159/000448173","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27867940"},{"pmid":"30624029","title":"OXTR methylation modulates exogenous oxytocin effects on human brain activity during social interaction.","doi":"10.1111/gbb.12555","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30624029"},{"pmid":"31900042","title":"Examining the role of mother-child interactions and DNA methylation of the oxytocin receptor gene in understanding child controlling attachment behaviors.","doi":"10.1080/14616734.2019.1708422","year":"2021","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31900042"},{"pmid":"30585381","title":"Oxytocin inhibits methamphetamine-associated learning and memory alterations by regulating DNA methylation at the Synaptophysin promoter.","doi":"10.1111/adb.12697","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30585381"},{"pmid":"27108164","title":"Oxytocin receptor DNA methylation in postpartum depression.","doi":"10.1016/j.psyneuen.2016.04.008","year":"2016","status":"Included in evidence supplement","reason":"Relevant OXTR transcriptional-regulation evidence reviewed","url":"https://europepmc.org/article/MED/27108164"},{"pmid":"30308385","title":"Oxytocin receptor gene methylation and substance use problems among young African American men.","doi":"10.1016/j.drugalcdep.2018.08.022","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30308385"},{"pmid":"28918249","title":"Perinatal depression and DNA methylation of oxytocin-related genes: a study of mothers and their children.","doi":"10.1016/j.yhbeh.2017.09.006","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/28918249"},{"pmid":"31542994","title":"Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes.","doi":"10.1080/15592294.2019.1656157","year":"2020","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31542994"},{"pmid":"29162179","title":"Variation in DNA methylation of the oxytocin receptor gene predicts children's resilience to prenatal stress.","doi":"10.1017/s0954579417001316","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29162179"},{"pmid":"31318641","title":"Childhood Adversity, Socioeconomic Instability, Oxytocin-Receptor-Gene Methylation, and Romantic-Relationship Support Among Young African American Men.","doi":"10.1177/0956797619854735","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31318641"},{"pmid":"31220321","title":"Reduced DNA Methylation of the Oxytocin Receptor Gene Is Associated With Anhedonia-Asociality in Women With Recent-Onset Schizophrenia and Ultra-high Risk for Psychosis.","doi":"10.1093/schbul/sbz016","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/31220321"},{"pmid":"28951495","title":"Increased methylation of the oxytocin receptor gene in motor functional neurological disorder: a preliminary study.","doi":"10.1136/jnnp-2017-316469","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/28951495"},{"pmid":"30690225","title":"Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness.","doi":"10.1016/j.psyneuen.2019.01.013","year":"2019","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/30690225"},{"pmid":"29407512","title":"Maternal depression, antidepressant use and placental oxytocin receptor DNA methylation: Findings from the MPEWS study.","doi":"10.1016/j.psyneuen.2018.01.004","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29407512"},{"pmid":"29843655","title":"The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review.","doi":"10.1186/s12888-018-1740-9","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29843655"},{"pmid":"27297999","title":"Systematic N-methylation of oxytocin: Impact on pharmacology and intramolecular hydrogen bonding network.","doi":"10.1016/j.bmc.2016.05.062","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27297999"},{"pmid":"25563749","title":"Oxytocin receptor gene methylation: converging multilevel evidence for a role in social anxiety.","doi":"10.1038/npp.2015.2","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25563749"},{"pmid":"27107296","title":"Maternal adversities during pregnancy and cord blood oxytocin receptor (OXTR) DNA methylation.","doi":"10.1093/scan/nsw051","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27107296"},{"pmid":"29628070","title":"Interactions Between Oxytocin Receptor Gene Methylation and Callous-Unemotional Traits Impact Socioaffective Brain Systems in Conduct-Disordered Offenders.","doi":"10.1016/j.bpsc.2017.12.010","year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/29628070"},{"pmid":"24523928","title":"Differential methylation of the oxytocin receptor gene in patients with anorexia nervosa: a pilot study.","doi":"10.1371/journal.pone.0088673","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/24523928"},{"pmid":"27520745","title":"Prenatal stress exposure, oxytocin receptor gene (OXTR) methylation, and child autistic traits: The moderating role of OXTR rs53576 genotype.","doi":"10.1002/aur.1681","year":"2017","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/27520745"},{"pmid":"26122287","title":"Natural variation in maternal care and cross-tissue patterns of oxytocin receptor gene methylation in rats.","doi":"10.1016/j.yhbeh.2015.05.022","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26122287"},{"pmid":"PMC5888730","title":"T187. ALTERED DNA METHYLATION OF THE OXYTOCIN RECEPTOR GENE IS ASSOCIATED WITH SUSCEPTIBILITY TO PSYCHOSIS AND ANHEDONIA-ASOCIALITY IN FEMALES: EPIGENETIC EVIDENCE IN RECENT-ONSET SCHIZOPHRENIA AND ULTRA-HIGH RISK FOR PSYCHOSIS","doi":null,"year":"2018","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/PMC/PMC5888730"},{"pmid":"25199917","title":"Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study.","doi":"10.1038/mp.2014.95","year":"2014","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/25199917"},{"pmid":"26257770","title":"Interaction between oxytocin receptor DNA methylation and genotype is associated with risk of postpartum depression in women without depression in pregnancy.","doi":"10.3389/fgene.2015.00243","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26257770"},{"pmid":"23087634","title":"DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli.","doi":"10.3389/fnhum.2012.00280","year":"2012","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/23087634"},{"pmid":"26977453","title":"Sex and diagnosis specific associations between DNA methylation of the oxytocin receptor gene with emotion processing and temporal-limbic and prefrontal brain volumes in psychotic disorders.","doi":"10.1016/j.bpsc.2015.10.003","year":"2016","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26977453"},{"pmid":"26175754","title":"DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women.","doi":"10.3389/fgene.2015.00230","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26175754"},{"pmid":"26061800","title":"Childhood maternal care is associated with DNA methylation of the genes for brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) in peripheral blood cells in adult men and women.","doi":"10.3109/10253890.2015.1038992","year":"2015","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/26061800"},{"pmid":"10210173","title":"Gonadotrophin-releasing hormone and oxytocin secretion from the hypothalamus in vitro during pro-oestrus: the effects of time of day and melatonin.","doi":"10.1016/s0361-9230(98)00151-8","year":"1999","status":"Search return; not included in this first extraction","reason":"No inclusion or exclusion judgement implied; full systematic screening remains open","url":"https://europepmc.org/article/MED/10210173"}]