Universal Informatics · Research reading room

An integrated relapse prevention and relationship safety intervention for women on methadone: testing short-term effects on intimate partner violence and substance use.

Gilbert L; El-Bassel N; Manuel J; Wu E; Go H; Golder S; Seewald R; Sanders G · Violence and victims · 2006 · Randomized controlled trial

Original publication · Original publication · Original publication · Original publication

Recorded summary

Reported reductions in selected minor physical/sexual and psychological IPV outcomes; drug-use reduction was not statistically significant.

Recorded limitations

Small pilot; selected violence outcomes and short follow-up limit transfer.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial
assessment
category
rct
is Randomized Controlled Trial
true
basis
Women randomly assigned to RPRS 16 or informational control 18.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

review Scope
abstract
trust Factor
scope
Paper
status
assessed
score
2
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
basis
Women randomly assigned to RPRS 16 or informational control 18.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

review Scope
abstract
human Approval
false
display Crosses
2
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
rating Scale
library-trust-factor/1-3
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial
intervention
Relapse Prevention and Relationship Safety intervention. Not established from accessed source.
comparator
Single informational session.
sample
Women randomly assigned to RPRS 16 or informational control 18.
measurement
Selected IPV outcomes; Drug use
timing
3 months
trial Id
relationship Note
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope. See limitation and quality fields; no population-wide clinical recommendation is implied.
measured Genes
None recorded
pathways
None recorded
source Access
level
abstract
source URLs

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

retrieved At
2026-10-30T07:15:55.705516+00:00
outcomes
  1. name
    Selected IPV outcomes
    follow Up
    3 months
    result
    Selected reductions favored intervention; numerical odds ratios omitted because reference direction is unclear in abstract.
    effect Estimate
    Not recorded
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
  2. name
    Drug use
    follow Up
    3 months
    result
    No statistically significant difference.
    effect Estimate
    p=.08
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
quality
risk Of Bias
Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
attrition
Not established from accessed source.
confounding
Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
adverse Findings
Adverse-event reporting not established from accessed source; absence of reporting is not evidence of no harm.
transfer Limits
Generalizability is limited to the stated population, setting and comparator.
jadad
not established
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
population
relation
direct
population
Women in methadone treatment meeting IPV and drug-use criteria.
exposure Evidence
Women in methadone treatment meeting IPV and drug-use criteria.
rationale
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
transfer Limit
See limitation and quality fields; no population-wide clinical recommendation is implied.
Topics and recorded topic scores
  1. key
    language:domestic-family-violence
    title
    Domestic & Family Violence
    collection
    language
    trust Score
    2
Citation snapshot and identifiers
id
dv-adult-therapy-17022356
doi
10.1891/0886-6708.21.5.657
pmid
17022356
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
language
Not recorded
Complete approved library record
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-01
assessment
AI assessed; human approved for publication
scope
Qualified research-library summaries. No professional clinical peer review or treatment recommendation is claimed.
source Revision
audit-r2-f3a54233bb82
source Content Hash
f3a54233bb82366b4e2286e4835fa70bc1f20f1d0eabcc8cad693c15e25b6f78
source Access
level
abstract
source URLs

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

retrieved At
2026-10-30T07:15:55.705516+00:00
editorial Audit
auditor
Codex (AI)
completed At
2026-10-31T05:11:05.655793+00:00
prior Content Hash
05cabc02f382c6d7c82daa4b177962e39571edb90178d2fca29194ee3c98bfc1
prior Revision
r1-05cabc02f382
prior Source
frozen-120
source Verification
id
dv-adult-therapy-17022356
doi
10.1891/0886-6708.21.5.657
pmid
17022356
fresh Metadata
Europe PMC core
metadata Retrieved
true
metadata SHA256
43ce85e5ad51280b575b9111c2fc055bc135b22ea7f1211f0dfde01917cb0eb6
claim Check
Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

applied Proposals
None recorded
method
AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
limitations

Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

study Family Id
RPRS-methadone-34-2006
family Linkage Uncertain
false
approaches
None recorded
id
dv-adult-therapy-17022356
aliases
None recorded
title
An integrated relapse prevention and relationship safety intervention for women on methadone: testing short-term effects on intimate partner violence and substance use.
journal
Violence and victims
neurotransmitters
None recorded
year
2006
authors
Gilbert L; El-Bassel N; Manuel J; Wu E; Go H; Golder S; Seewald R; Sanders G
design
Randomized controlled trial
kind
Journal article
identity Conflict
Not recorded
doi
10.1891/0886-6708.21.5.657
pmid
17022356
urls

https://doi.org/10.1891/0886-6708.21.5.657 · https://pubmed.ncbi.nlm.nih.gov/17022356/ · https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

collections

language

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
Reported reductions in selected minor physical/sexual and psychological IPV outcomes; drug-use reduction was not statistically significant.
limitation
Small pilot; selected violence outcomes and short follow-up limit transfer.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
rct
is Randomized Controlled Trial
true
basis
Women randomly assigned to RPRS 16 or informational control 18.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

review Scope
abstract
paper Trust Assessment
scope
Paper
status
assessed
score
2
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
basis
Women randomly assigned to RPRS 16 or informational control 18.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

review Scope
abstract
human Approval
false
display Crosses
2
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
rating Scale
library-trust-factor/1-3
citations By Collection
language
Not recorded
topics
  1. key
    language:domestic-family-violence
    title
    Domestic & Family Violence
    collection
    language
    trust Score
    2
journal Key
violenceandvictims
journal Label
Violence and victims
chapter Entries
  1. id
    language-dv-dv-adult-therapy-17022356
    aliases
    None recorded
    title
    An integrated relapse prevention and relationship safety intervention for women on methadone: testing short-term effects on intimate partner violence and substance use.
    authors
    Gilbert L; El-Bassel N; Manuel J; Wu E; Go H; Golder S; Seewald R; Sanders G
    year
    2006
    journal
    Violence and victims
    doi
    10.1891/0886-6708.21.5.657
    pmid
    17022356
    urls

    https://doi.org/10.1891/0886-6708.21.5.657 · https://pubmed.ncbi.nlm.nih.gov/17022356/ · https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    collections

    language

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    substance-use

    condition Evidence
    1. id
      substance-use
      evidence
      1. field
        title
        text
        An integrated relapse prevention and relationship safety intervention for women on methadone: testing short-term effects on intimate partner violence and substance use.
        matched Text
        methadone
      2. field
        population
        text
        Women in methadone treatment meeting IPV and drug-use criteria.
        matched Text
        methadone
      3. field
        outcomes
        text
        Selected IPV outcomes | Drug use
        matched Text
        Drug use
      scope
      Study population or investigated outcome; not a diagnosis or efficacy claim.
    age Groups

    not-specified

    age Population
    record Id
    dv-adult-therapy-17022356
    collections

    language

    groups

    not-specified

    reported Ages
    Not established from accessed source.
    youth Scope
    Not recorded
    youth Source Note
    Not recorded
    source URL
    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core
    basis Type
    source-limited-ai-editorial-assessment
    classification Note
    Original age terms: not-specified. Programme targets or possible eligibility are not counted as observed ages.
    community Matches
    1. category Id
      domestic-violence
      relation
      direct
    kind
    Journal article
    design
    Randomized controlled trial
    origin
    approved-dv-20261101
    priority
    1
    quotes
    None recorded
    finding
    Reported reductions in selected minor physical/sexual and psychological IPV outcomes; drug-use reduction was not statistically significant.
    summary
    Reported reductions in selected minor physical/sexual and psychological IPV outcomes; drug-use reduction was not statistically significant.
    limitation
    Small pilot; selected violence outcomes and short follow-up limit transfer.
    evidence
    evidence Type
    Randomized controlled trial
    intervention
    Relapse Prevention and Relationship Safety intervention. Not established from accessed source.
    comparator
    Single informational session.
    sample
    Women randomly assigned to RPRS 16 or informational control 18.
    measurement
    Selected IPV outcomes; Drug use
    timing
    3 months
    trial Id
    relationship Note
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope. See limitation and quality fields; no population-wide clinical recommendation is implied.
    measured Genes
    None recorded
    pathways
    None recorded
    source Access
    level
    abstract
    source URLs

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    retrieved At
    2026-10-30T07:15:55.705516+00:00
    outcomes
    1. name
      Selected IPV outcomes
      follow Up
      3 months
      result
      Selected reductions favored intervention; numerical odds ratios omitted because reference direction is unclear in abstract.
      effect Estimate
      Not recorded
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
    2. name
      Drug use
      follow Up
      3 months
      result
      No statistically significant difference.
      effect Estimate
      p=.08
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
    quality
    risk Of Bias
    Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
    attrition
    Not established from accessed source.
    confounding
    Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
    adverse Findings
    Adverse-event reporting not established from accessed source; absence of reporting is not evidence of no harm.
    transfer Limits
    Generalizability is limited to the stated population, setting and comparator.
    jadad
    not established
    masking Roles
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    population
    relation
    direct
    population
    Women in methadone treatment meeting IPV and drug-use criteria.
    exposure Evidence
    Women in methadone treatment meeting IPV and drug-use criteria.
    rationale
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
    transfer Limit
    See limitation and quality fields; no population-wide clinical recommendation is implied.
    study Design Assessment
    category
    rct
    is Randomized Controlled Trial
    true
    basis
    Women randomly assigned to RPRS 16 or informational control 18.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    review Scope
    abstract
    paper Trust Assessment
    scope
    Paper
    status
    assessed
    score
    2
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    basis
    Women randomly assigned to RPRS 16 or informational control 18.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    review Scope
    abstract
    human Approval
    false
    display Crosses
    2
    masking Roles
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    rating Scale
    library-trust-factor/1-3
    jadad
    status
    unassessed
    score
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    citation Count
    Not recorded
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-01
    assessment
    AI assessed; human approved for publication
    scope
    Qualified research-library summaries. No professional clinical peer review or treatment recommendation is claimed.
    source Revision
    audit-r2-f3a54233bb82
    source Content Hash
    f3a54233bb82366b4e2286e4835fa70bc1f20f1d0eabcc8cad693c15e25b6f78
    source Access
    level
    abstract
    source URLs

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    retrieved At
    2026-10-30T07:15:55.705516+00:00
    study Family Id
    RPRS-methadone-34-2006
    family Linkage Uncertain
    false
    approaches
    None recorded
    record Id
    dv-adult-therapy-17022356
    source Pages
    None recorded
    editorial Audit
    auditor
    Codex (AI)
    completed At
    2026-10-31T05:11:05.655793+00:00
    prior Content Hash
    05cabc02f382c6d7c82daa4b177962e39571edb90178d2fca29194ee3c98bfc1
    prior Revision
    r1-05cabc02f382
    prior Source
    frozen-120
    source Verification
    id
    dv-adult-therapy-17022356
    doi
    10.1891/0886-6708.21.5.657
    pmid
    17022356
    fresh Metadata
    Europe PMC core
    metadata Retrieved
    true
    metadata SHA256
    43ce85e5ad51280b575b9111c2fc055bc135b22ea7f1211f0dfde01917cb0eb6
    claim Check
    Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    applied Proposals
    None recorded
    method
    AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
    limitations

    Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

    assessment Record
    id
    dv-adult-therapy-17022356
    title
    An integrated relapse prevention and relationship safety intervention for women on methadone: testing short-term effects on intimate partner violence and substance use.
    authors

    Gilbert L · El-Bassel N · Manuel J · Wu E · Go H · Golder S · Seewald R · Sanders G

    year
    2006
    journal
    Violence and victims
    doi
    10.1891/0886-6708.21.5.657
    pmid
    17022356
    trial Registration
    None recorded
    collection
    language
    intervention Family
    Relapse Prevention and Relationship Safety intervention.
    publication Type
    Primary intervention study
    study Family Id
    RPRS-methadone-34-2006
    family Linkage Uncertain
    false
    existing Repository Matches
    None recorded
    relevance
    relation
    direct
    population
    Women in methadone treatment meeting IPV and drug-use criteria.
    exposure Evidence
    Women in methadone treatment meeting IPV and drug-use criteria.
    rationale
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
    transfer Limit
    See limitation and quality fields; no population-wide clinical recommendation is implied.
    age
    groups

    not-specified

    reported Range
    Not established from accessed source.
    youth Scope
    Not recorded
    country
    Not established from accessed source.
    setting
    Not established from accessed source.
    sample Size
    randomized
    34
    analyzed
    Not recorded
    description
    Women randomly assigned to RPRS 16 or informational control 18.
    intervention
    description
    Relapse Prevention and Relationship Safety intervention.
    dose
    Not established from accessed source.
    provider
    Not established from accessed source.
    comparator
    Single informational session.
    outcomes
    1. name
      Selected IPV outcomes
      follow Up
      3 months
      result
      Selected reductions favored intervention; numerical odds ratios omitted because reference direction is unclear in abstract.
      effect Estimate
      Not recorded
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
    2. name
      Drug use
      follow Up
      3 months
      result
      No statistically significant difference.
      effect Estimate
      p=.08
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
    finding
    Reported reductions in selected minor physical/sexual and psychological IPV outcomes; drug-use reduction was not statistically significant.
    limitation
    Small pilot; selected violence outcomes and short follow-up limit transfer.
    design
    type
    Randomized controlled trial
    randomization Evidence
    Women randomly assigned to RPRS 16 or informational control 18.
    masking
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    crosses
    1
    cross Rationale
    One cross: random allocation explicitly described; double-blinded treatment not established.
    quality
    risk Of Bias
    Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
    attrition
    Not established from accessed source.
    confounding
    Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
    adverse Findings
    Adverse-event reporting not established from accessed source; absence of reporting is not evidence of no harm.
    transfer Limits
    Generalizability is limited to the stated population, setting and comparator.
    jadad
    not established
    access
    level
    abstract
    source URLs

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    retrieved At
    2026-10-30T07:15:55.705516+00:00
    sources
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      type
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      retrieved At
      2026-10-30T07:15:55.705516+00:00
      identity Verified
      true
      notes
      Primary-publication abstract and bibliographic metadata accessed; canonical PubMed record: https://pubmed.ncbi.nlm.nih.gov/17022356/
      retrieval Query URL
      https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE_ABS%3A%28%22intimate+partner+violence%22+OR+%22domestic+violence%22+OR+%22battered+women%22%29+AND+TITLE_ABS%3A%28randomized+OR+randomised%29+AND+TITLE_ABS%3A%28therapy+OR+psychological+OR+psychotherapy+OR+cognitive+OR+counseling+OR+counselling+OR+%22motivational+interviewing%22%29&format=json&resultType=core&pageSize=1000
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      retrieved At
      2026-10-30T07:20:03.411719+00:00
      identity Verified
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      notes
      DOI identity cross-check; metadata title: An Integrated Relapse Prevention and Relationship Safety Intervention for Women on Methadone: Testing Short-Term Effects on Intimate Partner Violence and Substance Use. Correction/update relations checked.
    publication Status
    status
    ppublish
    correction Retraction Check
    europe PMCpub Types

    Randomized Controlled Trial · Journal Article

    crossref Update Relations
    None recorded
    crossref Relations
    crossref Checked
    true
    uncertainty
    No comprehensive publisher/Crossmark or registry audit claimed; correction/retraction absence is limited to accessed metadata.
    recommendation Rationale
    Retain as pending candidate evidence; interpret the study design, null outcomes and access limits together.
    review
    status
    pending
    reviewer
    Not recorded
    assessment Status
    assessed
    assessment Notes

    Bibliographic identity and abstract-level evidence extracted; full-text appraisal remains limited unless explicitly stated. · Study-family label is retained separately from publication identity; this does not prove independence from every unpublished or secondary report.

    review Ready
    true
    review Readiness
    ai-editorial-audit-complete-release-pending
    research Lane
    adult-therapy
    publication Recommendation
    status
    recommended-summary
    reason
    Suitable as a qualified research-library summary at the stated source-access level. This is not a conclusion that the intervention is effective or safe.
    scope
    Research summary only; no treatment recommendation
    human Release Approval
    false
    editorial Audit
    auditor
    Codex (AI)
    completed At
    2026-10-31T05:11:05.655793+00:00
    prior Content Hash
    05cabc02f382c6d7c82daa4b177962e39571edb90178d2fca29194ee3c98bfc1
    prior Revision
    r1-05cabc02f382
    prior Source
    frozen-120
    source Verification
    id
    dv-adult-therapy-17022356
    doi
    10.1891/0886-6708.21.5.657
    pmid
    17022356
    fresh Metadata
    Europe PMC core
    metadata Retrieved
    true
    metadata SHA256
    43ce85e5ad51280b575b9111c2fc055bc135b22ea7f1211f0dfde01917cb0eb6
    claim Check
    Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    applied Proposals
    None recorded
    method
    AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
    limitations

    Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

    study Design Assessment
    category
    rct
    is Randomized Controlled Trial
    true
    basis
    Women randomly assigned to RPRS 16 or informational control 18.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    review Scope
    abstract
    paper Trust Assessment
    scope
    Paper
    status
    assessed
    score
    2
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    basis
    One cross: random allocation explicitly described; double-blinded treatment not established.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    review Scope
    abstract
    human Approval
    false
    display Crosses
    1
    masking Roles
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    jadad
    status
    unassessed
    score
    Not recorded
    evidence
    population
    relation
    direct
    population
    Women in methadone treatment meeting IPV and drug-use criteria.
    exposure Evidence
    Women in methadone treatment meeting IPV and drug-use criteria.
    rationale
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
    transfer Limit
    See limitation and quality fields; no population-wide clinical recommendation is implied.
    intervention
    description
    Relapse Prevention and Relationship Safety intervention.
    dose
    Not established from accessed source.
    provider
    Not established from accessed source.
    comparator
    Single informational session.
    outcomes
    1. name
      Selected IPV outcomes
      follow Up
      3 months
      result
      Selected reductions favored intervention; numerical odds ratios omitted because reference direction is unclear in abstract.
      effect Estimate
      Not recorded
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
    2. name
      Drug use
      follow Up
      3 months
      result
      No statistically significant difference.
      effect Estimate
      p=.08
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
    access
    level
    abstract
    source URLs

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

    retrieved At
    2026-10-30T07:15:55.705516+00:00
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    provenance
    Discovered by AI
    content Hash
    f3a54233bb82366b4e2286e4835fa70bc1f20f1d0eabcc8cad693c15e25b6f78
    revision
    audit-r2-f3a54233bb82
    archive Entries
    None recorded
    collection
    language
    chapter Number
    5
    topic Id
    domestic-family-violence
    topic Title
    Domestic & Family Violence
    trust Score
    2
evidence
evidence Type
Randomized controlled trial
intervention
Relapse Prevention and Relationship Safety intervention. Not established from accessed source.
comparator
Single informational session.
sample
Women randomly assigned to RPRS 16 or informational control 18.
measurement
Selected IPV outcomes; Drug use
timing
3 months
trial Id
relationship Note
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope. See limitation and quality fields; no population-wide clinical recommendation is implied.
measured Genes
None recorded
pathways
None recorded
source Access
level
abstract
source URLs

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17022356%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1891%2F0886-6708.21.5.657

retrieved At
2026-10-30T07:15:55.705516+00:00
outcomes
  1. name
    Selected IPV outcomes
    follow Up
    3 months
    result
    Selected reductions favored intervention; numerical odds ratios omitted because reference direction is unclear in abstract.
    effect Estimate
    Not recorded
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
  2. name
    Drug use
    follow Up
    3 months
    result
    No statistically significant difference.
    effect Estimate
    p=.08
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Primary versus secondary status not fully established; see finding for explicitly identified secondary outcomes.
quality
risk Of Bias
Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
attrition
Not established from accessed source.
confounding
Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
adverse Findings
Adverse-event reporting not established from accessed source; absence of reporting is not evidence of no harm.
transfer Limits
Generalizability is limited to the stated population, setting and comparator.
jadad
not established
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
population
relation
direct
population
Women in methadone treatment meeting IPV and drug-use criteria.
exposure Evidence
Women in methadone treatment meeting IPV and drug-use criteria.
rationale
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
transfer Limit
See limitation and quality fields; no population-wide clinical recommendation is implied.
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    substance-use
    evidence
    1. field
      title
      text
      An integrated relapse prevention and relationship safety intervention for women on methadone: testing short-term effects on intimate partner violence and substance use.
      matched Text
      methadone
    2. field
      population
      text
      Women in methadone treatment meeting IPV and drug-use criteria.
      matched Text
      methadone
    3. field
      outcomes
      text
      Selected IPV outcomes | Drug use
      matched Text
      Drug use
    scope
    Study population or investigated outcome; not a diagnosis or efficacy claim.
conditions

substance-use

topic Trust Scores

2

full Text
status
not-indexed
retrieval Available
false

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