Universal Informatics · Research reading room

Individually tailored Internet-delivered cognitive-behavioral therapy for survivors of intimate partner violence: A randomized controlled pilot trial.

Andersson G; Olsson E; Ringsgård E; Sandgren T; Viklund I; Andersson C; Hesselman Y; Johansson R; Nordgren LB; Bohman B · Internet interventions · 2021 · Randomized controlled trial

Original publication · Original publication · Original publication · Original publication · Original publication

Recorded summary

Some PTSD/depression measures favored guided internet CBT, while others did not. Follow-up improvements after both arms received treatment are within-group findings.

Recorded limitations

Small feasibility study, waitlist comparison, moderate adherence and substantial long-term attrition. Ongoing IPV excluded; later follow-up lacked an untreated comparator.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial
assessment
category
rct
is Randomized Controlled Trial
true
basis
Independent person used a random-number service for 1:1 allocation: 32 per arm.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

review Scope
full-text
trust Factor
scope
Paper
status
assessed
score
2
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
basis
Independent person used a random-number service for 1:1 allocation: 32 per arm.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

review Scope
full-text
human Approval
false
display Crosses
2
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
rating Scale
library-trust-factor/1-3
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial
intervention
Individually tailored internet CBT with guided self-help. Eight weeks; symptom-focused modules.
comparator
Waitlist with delayed treatment.
sample
64 randomized and included in multilevel models; 58 completed post-treatment assessment and 42 follow-up.
measurement
PTSD, IES-R; Depression, BDI-II; PDS, PHQ-9, anxiety and quality of life
timing
Post-treatment
trial Id
relationship Note
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope. See limitation and quality fields; no population-wide clinical recommendation is implied.
measured Genes
None recorded
pathways
None recorded
source Access
level
full-text
source URLs

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

retrieved At
2026-10-30T07:15:55.705516+00:00
outcomes
  1. name
    PTSD, IES-R
    follow Up
    Post-treatment
    result
    Favored treatment.
    effect Estimate
    d=.89; 95% CI .41–1.36
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Preliminary efficacy outcome; feasibility was the primary study aim.
  2. name
    Depression, BDI-II
    follow Up
    Post-treatment
    result
    Favored treatment.
    effect Estimate
    d=.86; 95% CI .22–1.50
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Preliminary efficacy outcome; feasibility was the primary study aim.
  3. name
    PDS, PHQ-9, anxiety and quality of life
    follow Up
    Post-treatment
    result
    No significant between-group differences.
    effect Estimate
    Not recorded
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Preliminary efficacy outcome; feasibility was the primary study aim.
quality
risk Of Bias
Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
attrition
Six missed post-treatment (five intervention, one control); follow-up 42/64. Average five of eight modules completed.
confounding
Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
adverse Findings
Reliable post-treatment deterioration occurred: PTSD measure 1/26 intervention versus 3/30 control; depression measure 5/26 versus 7/30. These are symptom changes, not adjudicated treatment harms.
transfer Limits
Generalizability is limited to the stated population, setting and comparator.
jadad
not established
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
population
relation
direct
population
63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
exposure Evidence
63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
rationale
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
transfer Limit
See limitation and quality fields; no population-wide clinical recommendation is implied.
Topics and recorded topic scores
  1. key
    language:domestic-family-violence
    title
    Domestic & Family Violence
    collection
    language
    trust Score
    2
Citation snapshot and identifiers
id
dv-adult-therapy-34584851
doi
10.1016/j.invent.2021.100453
pmid
34584851
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
language
Not recorded
Complete approved library record
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-01
assessment
AI assessed; human approved for publication
scope
Qualified research-library summaries. No professional clinical peer review or treatment recommendation is claimed.
source Revision
audit-r2-6b51a80717f4
source Content Hash
6b51a80717f422cb178106dc10c801bfb15dcbd78f696b58beab8e07aa236dec
source Access
level
full-text
source URLs

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

retrieved At
2026-10-30T07:15:55.705516+00:00
editorial Audit
auditor
Codex (AI)
completed At
2026-10-31T05:11:05.655793+00:00
prior Content Hash
e29c58531ec96f7b1d3b8b396648f0b17458b3c579037cf84d6b0da81d9b71a0
prior Revision
r1-e29c58531ec9
prior Source
frozen-120
source Verification
id
dv-adult-therapy-34584851
doi
10.1016/j.invent.2021.100453
pmid
34584851
fresh Metadata
Europe PMC core
metadata Retrieved
true
metadata SHA256
02f71fbfea21d6ab8a1a11e5af542b860f07627d6a750b9f138546a3bce4c101
claim Check
Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

applied Proposals
None recorded
method
AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
limitations

Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

study Family Id
ICBT-IPV-64-2021
family Linkage Uncertain
false
approaches
None recorded
id
dv-adult-therapy-34584851
aliases
None recorded
title
Individually tailored Internet-delivered cognitive-behavioral therapy for survivors of intimate partner violence: A randomized controlled pilot trial.
journal
Internet interventions
neurotransmitters
None recorded
year
2021
authors
Andersson G; Olsson E; Ringsgård E; Sandgren T; Viklund I; Andersson C; Hesselman Y; Johansson R; Nordgren LB; Bohman B
design
Randomized controlled trial
kind
Journal article
identity Conflict
Not recorded
doi
10.1016/j.invent.2021.100453
pmid
34584851
urls

https://doi.org/10.1016/j.invent.2021.100453 · https://pubmed.ncbi.nlm.nih.gov/34584851/ · https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

collections

language

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
Some PTSD/depression measures favored guided internet CBT, while others did not. Follow-up improvements after both arms received treatment are within-group findings.
limitation
Small feasibility study, waitlist comparison, moderate adherence and substantial long-term attrition. Ongoing IPV excluded; later follow-up lacked an untreated comparator.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
rct
is Randomized Controlled Trial
true
basis
Independent person used a random-number service for 1:1 allocation: 32 per arm.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

review Scope
full-text
paper Trust Assessment
scope
Paper
status
assessed
score
2
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
basis
Independent person used a random-number service for 1:1 allocation: 32 per arm.
sources

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

review Scope
full-text
human Approval
false
display Crosses
2
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
rating Scale
library-trust-factor/1-3
citations By Collection
language
Not recorded
topics
  1. key
    language:domestic-family-violence
    title
    Domestic & Family Violence
    collection
    language
    trust Score
    2
journal Key
internetinterventions
journal Label
Internet interventions
chapter Entries
  1. id
    language-dv-dv-adult-therapy-34584851
    aliases
    None recorded
    title
    Individually tailored Internet-delivered cognitive-behavioral therapy for survivors of intimate partner violence: A randomized controlled pilot trial.
    authors
    Andersson G; Olsson E; Ringsgård E; Sandgren T; Viklund I; Andersson C; Hesselman Y; Johansson R; Nordgren LB; Bohman B
    year
    2021
    journal
    Internet interventions
    doi
    10.1016/j.invent.2021.100453
    pmid
    34584851
    urls

    https://doi.org/10.1016/j.invent.2021.100453 · https://pubmed.ncbi.nlm.nih.gov/34584851/ · https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    collections

    language

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · ptsd · depression

    condition Evidence
    1. id
      anxiety
      evidence
      1. field
        outcomes
        text
        PTSD, IES-R | Depression, BDI-II | PDS, PHQ-9, anxiety and quality of life
        matched Text
        anxiety
      scope
      Study population or investigated outcome; not a diagnosis or efficacy claim.
    2. id
      ptsd
      evidence
      1. field
        outcomes
        text
        PTSD, IES-R | Depression, BDI-II | PDS, PHQ-9, anxiety and quality of life
        matched Text
        PTSD
      scope
      Study population or investigated outcome; not a diagnosis or efficacy claim.
    3. id
      depression
      evidence
      1. field
        outcomes
        text
        PTSD, IES-R | Depression, BDI-II | PDS, PHQ-9, anxiety and quality of life
        matched Text
        Depression
      scope
      Study population or investigated outcome; not a diagnosis or efficacy claim.
    age Groups

    youth · adults · older-adults

    age Population
    record Id
    dv-adult-therapy-34584851
    collections

    language

    groups

    youth · adults · older-adults

    reported Ages
    23–72 years
    youth Scope
    included
    youth Source Note
    included
    source URL
    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core
    basis Type
    source-limited-ai-editorial-assessment
    classification Note
    Original age terms: youth, adults, older-adults. Programme targets or possible eligibility are not counted as observed ages.
    community Matches
    1. category Id
      domestic-violence
      relation
      direct
    kind
    Journal article
    design
    Randomized controlled trial
    origin
    approved-dv-20261101
    priority
    1
    quotes
    None recorded
    finding
    Some PTSD/depression measures favored guided internet CBT, while others did not. Follow-up improvements after both arms received treatment are within-group findings.
    summary
    Some PTSD/depression measures favored guided internet CBT, while others did not. Follow-up improvements after both arms received treatment are within-group findings.
    limitation
    Small feasibility study, waitlist comparison, moderate adherence and substantial long-term attrition. Ongoing IPV excluded; later follow-up lacked an untreated comparator.
    evidence
    evidence Type
    Randomized controlled trial
    intervention
    Individually tailored internet CBT with guided self-help. Eight weeks; symptom-focused modules.
    comparator
    Waitlist with delayed treatment.
    sample
    64 randomized and included in multilevel models; 58 completed post-treatment assessment and 42 follow-up.
    measurement
    PTSD, IES-R; Depression, BDI-II; PDS, PHQ-9, anxiety and quality of life
    timing
    Post-treatment
    trial Id
    relationship Note
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope. See limitation and quality fields; no population-wide clinical recommendation is implied.
    measured Genes
    None recorded
    pathways
    None recorded
    source Access
    level
    full-text
    source URLs

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    retrieved At
    2026-10-30T07:15:55.705516+00:00
    outcomes
    1. name
      PTSD, IES-R
      follow Up
      Post-treatment
      result
      Favored treatment.
      effect Estimate
      d=.89; 95% CI .41–1.36
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    2. name
      Depression, BDI-II
      follow Up
      Post-treatment
      result
      Favored treatment.
      effect Estimate
      d=.86; 95% CI .22–1.50
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    3. name
      PDS, PHQ-9, anxiety and quality of life
      follow Up
      Post-treatment
      result
      No significant between-group differences.
      effect Estimate
      Not recorded
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    quality
    risk Of Bias
    Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
    attrition
    Six missed post-treatment (five intervention, one control); follow-up 42/64. Average five of eight modules completed.
    confounding
    Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
    adverse Findings
    Reliable post-treatment deterioration occurred: PTSD measure 1/26 intervention versus 3/30 control; depression measure 5/26 versus 7/30. These are symptom changes, not adjudicated treatment harms.
    transfer Limits
    Generalizability is limited to the stated population, setting and comparator.
    jadad
    not established
    masking Roles
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    population
    relation
    direct
    population
    63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
    exposure Evidence
    63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
    rationale
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
    transfer Limit
    See limitation and quality fields; no population-wide clinical recommendation is implied.
    study Design Assessment
    category
    rct
    is Randomized Controlled Trial
    true
    basis
    Independent person used a random-number service for 1:1 allocation: 32 per arm.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    review Scope
    full-text
    paper Trust Assessment
    scope
    Paper
    status
    assessed
    score
    2
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    basis
    Independent person used a random-number service for 1:1 allocation: 32 per arm.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    review Scope
    full-text
    human Approval
    false
    display Crosses
    2
    masking Roles
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    rating Scale
    library-trust-factor/1-3
    jadad
    status
    unassessed
    score
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    citation Count
    Not recorded
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-01
    assessment
    AI assessed; human approved for publication
    scope
    Qualified research-library summaries. No professional clinical peer review or treatment recommendation is claimed.
    source Revision
    audit-r2-6b51a80717f4
    source Content Hash
    6b51a80717f422cb178106dc10c801bfb15dcbd78f696b58beab8e07aa236dec
    source Access
    level
    full-text
    source URLs

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    retrieved At
    2026-10-30T07:15:55.705516+00:00
    study Family Id
    ICBT-IPV-64-2021
    family Linkage Uncertain
    false
    approaches
    None recorded
    record Id
    dv-adult-therapy-34584851
    source Pages
    None recorded
    editorial Audit
    auditor
    Codex (AI)
    completed At
    2026-10-31T05:11:05.655793+00:00
    prior Content Hash
    e29c58531ec96f7b1d3b8b396648f0b17458b3c579037cf84d6b0da81d9b71a0
    prior Revision
    r1-e29c58531ec9
    prior Source
    frozen-120
    source Verification
    id
    dv-adult-therapy-34584851
    doi
    10.1016/j.invent.2021.100453
    pmid
    34584851
    fresh Metadata
    Europe PMC core
    metadata Retrieved
    true
    metadata SHA256
    02f71fbfea21d6ab8a1a11e5af542b860f07627d6a750b9f138546a3bce4c101
    claim Check
    Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    applied Proposals
    None recorded
    method
    AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
    limitations

    Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

    assessment Record
    id
    dv-adult-therapy-34584851
    title
    Individually tailored Internet-delivered cognitive-behavioral therapy for survivors of intimate partner violence: A randomized controlled pilot trial.
    authors

    Andersson G · Olsson E · Ringsgård E · Sandgren T · Viklund I · Andersson C · Hesselman Y · Johansson R · Nordgren LB · Bohman B

    year
    2021
    journal
    Internet interventions
    doi
    10.1016/j.invent.2021.100453
    pmid
    34584851
    trial Registration
    None recorded
    collection
    language
    intervention Family
    Individually tailored internet CBT with guided self-help.
    publication Type
    Primary intervention study
    study Family Id
    ICBT-IPV-64-2021
    family Linkage Uncertain
    false
    existing Repository Matches
    None recorded
    relevance
    relation
    direct
    population
    63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
    exposure Evidence
    63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
    rationale
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
    transfer Limit
    See limitation and quality fields; no population-wide clinical recommendation is implied.
    age
    groups

    youth · adults · older-adults

    reported Range
    23–72 years
    youth Scope
    included
    country
    Sweden
    setting
    Online self-help.
    sample Size
    randomized
    64
    analyzed
    64
    description
    64 randomized and included in multilevel models; 58 completed post-treatment assessment and 42 follow-up.
    intervention
    description
    Individually tailored internet CBT with guided self-help.
    dose
    Eight weeks; symptom-focused modules.
    provider
    Not established from accessed source.
    comparator
    Waitlist with delayed treatment.
    outcomes
    1. name
      PTSD, IES-R
      follow Up
      Post-treatment
      result
      Favored treatment.
      effect Estimate
      d=.89; 95% CI .41–1.36
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    2. name
      Depression, BDI-II
      follow Up
      Post-treatment
      result
      Favored treatment.
      effect Estimate
      d=.86; 95% CI .22–1.50
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    3. name
      PDS, PHQ-9, anxiety and quality of life
      follow Up
      Post-treatment
      result
      No significant between-group differences.
      effect Estimate
      Not recorded
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    finding
    Some PTSD/depression measures favored guided internet CBT, while others did not. Follow-up improvements after both arms received treatment are within-group findings.
    limitation
    Small feasibility study, waitlist comparison, moderate adherence and substantial long-term attrition. Ongoing IPV excluded; later follow-up lacked an untreated comparator.
    design
    type
    Randomized controlled trial
    randomization Evidence
    Independent person used a random-number service for 1:1 allocation: 32 per arm.
    masking
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    crosses
    1
    cross Rationale
    One cross: random allocation explicitly described; double-blinded treatment not established.
    quality
    risk Of Bias
    Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
    attrition
    Six missed post-treatment (five intervention, one control); follow-up 42/64. Average five of eight modules completed.
    confounding
    Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
    adverse Findings
    Reliable post-treatment deterioration occurred: PTSD measure 1/26 intervention versus 3/30 control; depression measure 5/26 versus 7/30. These are symptom changes, not adjudicated treatment harms.
    transfer Limits
    Generalizability is limited to the stated population, setting and comparator.
    jadad
    not established
    access
    level
    full-text
    source URLs

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    retrieved At
    2026-10-30T07:15:55.705516+00:00
    sources
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      type
      Europe PMC core record sourced from PubMed/MEDLINE
      retrieved At
      2026-10-30T07:15:55.705516+00:00
      identity Verified
      true
      notes
      Primary-publication abstract and bibliographic metadata accessed; canonical PubMed record: https://pubmed.ncbi.nlm.nih.gov/34584851/
      retrieval Query URL
      https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE_ABS%3A%28%22intimate+partner+violence%22+OR+%22domestic+violence%22+OR+%22battered+women%22%29+AND+TITLE_ABS%3A%28randomized+OR+randomised%29+AND+TITLE_ABS%3A%28therapy+OR+psychological+OR+psychotherapy+OR+cognitive+OR+counseling+OR+counselling+OR+%22motivational+interviewing%22%29&format=json&resultType=core&pageSize=1000
    2. url
      https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453
      type
      Crossref DOI registration metadata
      retrieved At
      2026-10-30T07:19:58.723358+00:00
      identity Verified
      true
      notes
      DOI identity cross-check; metadata title: Individually tailored Internet-delivered cognitive-behavioral therapy for survivors of intimate partner violence: A randomized controlled pilot trial. Correction/update relations checked.
    3. url
      https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/
      type
      Primary paper open-access methods/results
      retrieved At
      2026-10-30T07:17:50.456399+00:00
      identity Verified
      true
      notes
      Primary-paper methods, results and discussion inspected.
    publication Status
    status
    epublish
    correction Retraction Check
    europe PMCpub Types

    research-article · Journal Article

    crossref Update Relations
    None recorded
    crossref Relations
    crossref Checked
    true
    uncertainty
    No comprehensive publisher/Crossmark or registry audit claimed; correction/retraction absence is limited to accessed metadata.
    recommendation Rationale
    Retain as pending candidate evidence; interpret the study design, null outcomes and access limits together.
    review
    status
    pending
    reviewer
    Not recorded
    assessment Status
    assessed
    assessment Notes

    Full paper available; methods, outcomes, missingness and discussion examined. Formal risk-of-bias scoring and comprehensive correction audit remain incomplete. · Study-family label is retained separately from publication identity; this does not prove independence from every unpublished or secondary report.

    review Ready
    true
    review Readiness
    ai-editorial-audit-complete-release-pending
    research Lane
    adult-therapy
    publication Recommendation
    status
    recommended-summary
    reason
    Suitable as a qualified research-library summary at the stated source-access level. This is not a conclusion that the intervention is effective or safe.
    scope
    Research summary only; no treatment recommendation
    human Release Approval
    false
    editorial Audit
    auditor
    Codex (AI)
    completed At
    2026-10-31T05:11:05.655793+00:00
    prior Content Hash
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    frozen-120
    source Verification
    id
    dv-adult-therapy-34584851
    doi
    10.1016/j.invent.2021.100453
    pmid
    34584851
    fresh Metadata
    Europe PMC core
    metadata Retrieved
    true
    metadata SHA256
    02f71fbfea21d6ab8a1a11e5af542b860f07627d6a750b9f138546a3bce4c101
    claim Check
    Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    applied Proposals
    None recorded
    method
    AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
    limitations

    Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

    study Design Assessment
    category
    rct
    is Randomized Controlled Trial
    true
    basis
    Independent person used a random-number service for 1:1 allocation: 32 per arm.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    review Scope
    full-text
    paper Trust Assessment
    scope
    Paper
    status
    assessed
    score
    2
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    basis
    One cross: random allocation explicitly described; double-blinded treatment not established.
    sources

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    review Scope
    full-text
    human Approval
    false
    display Crosses
    1
    masking Roles
    participants
    Not established from accessed source.
    providers
    Not established from accessed source.
    assessors
    Not established from accessed source.
    analysts
    Not established from accessed source.
    jadad
    status
    unassessed
    score
    Not recorded
    evidence
    population
    relation
    direct
    population
    63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
    exposure Evidence
    63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
    rationale
    Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
    transfer Limit
    See limitation and quality fields; no population-wide clinical recommendation is implied.
    intervention
    description
    Individually tailored internet CBT with guided self-help.
    dose
    Eight weeks; symptom-focused modules.
    provider
    Not established from accessed source.
    comparator
    Waitlist with delayed treatment.
    outcomes
    1. name
      PTSD, IES-R
      follow Up
      Post-treatment
      result
      Favored treatment.
      effect Estimate
      d=.89; 95% CI .41–1.36
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    2. name
      Depression, BDI-II
      follow Up
      Post-treatment
      result
      Favored treatment.
      effect Estimate
      d=.86; 95% CI .22–1.50
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    3. name
      PDS, PHQ-9, anxiety and quality of life
      follow Up
      Post-treatment
      result
      No significant between-group differences.
      effect Estimate
      Not recorded
      uncertainty
      Confidence interval included when stated; otherwise not established from accessed source.
      primary Status
      Preliminary efficacy outcome; feasibility was the primary study aim.
    access
    level
    full-text
    source URLs

    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

    retrieved At
    2026-10-30T07:15:55.705516+00:00
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    provenance
    Discovered by AI
    content Hash
    6b51a80717f422cb178106dc10c801bfb15dcbd78f696b58beab8e07aa236dec
    revision
    audit-r2-6b51a80717f4
    archive Entries
    None recorded
    collection
    language
    chapter Number
    5
    topic Id
    domestic-family-violence
    topic Title
    Domestic & Family Violence
    trust Score
    2
evidence
evidence Type
Randomized controlled trial
intervention
Individually tailored internet CBT with guided self-help. Eight weeks; symptom-focused modules.
comparator
Waitlist with delayed treatment.
sample
64 randomized and included in multilevel models; 58 completed post-treatment assessment and 42 follow-up.
measurement
PTSD, IES-R; Depression, BDI-II; PDS, PHQ-9, anxiety and quality of life
timing
Post-treatment
trial Id
relationship Note
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope. See limitation and quality fields; no population-wide clinical recommendation is implied.
measured Genes
None recorded
pathways
None recorded
source Access
level
full-text
source URLs

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:34584851%20AND%20SRC:MED&format=json&resultType=core · https://api.crossref.org/works/10.1016%2Fj.invent.2021.100453 · https://pmc.ncbi.nlm.nih.gov/articles/PMC8452796/

retrieved At
2026-10-30T07:15:55.705516+00:00
outcomes
  1. name
    PTSD, IES-R
    follow Up
    Post-treatment
    result
    Favored treatment.
    effect Estimate
    d=.89; 95% CI .41–1.36
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Preliminary efficacy outcome; feasibility was the primary study aim.
  2. name
    Depression, BDI-II
    follow Up
    Post-treatment
    result
    Favored treatment.
    effect Estimate
    d=.86; 95% CI .22–1.50
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Preliminary efficacy outcome; feasibility was the primary study aim.
  3. name
    PDS, PHQ-9, anxiety and quality of life
    follow Up
    Post-treatment
    result
    No significant between-group differences.
    effect Estimate
    Not recorded
    uncertainty
    Confidence interval included when stated; otherwise not established from accessed source.
    primary Status
    Preliminary efficacy outcome; feasibility was the primary study aim.
quality
risk Of Bias
Provisional appraisal; see limitations, attrition and masking. No formal risk-of-bias score assigned.
attrition
Six missed post-treatment (five intervention, one control); follow-up 42/64. Average five of eight modules completed.
confounding
Random allocation addresses baseline confounding if implemented; allocation concealment and analysis details remain source-dependent.
adverse Findings
Reliable post-treatment deterioration occurred: PTSD measure 1/26 intervention versus 3/30 control; depression measure 5/26 versus 7/30. These are symptom changes, not adjudicated treatment harms.
transfer Limits
Generalizability is limited to the stated population, setting and comparator.
jadad
not established
masking Roles
participants
Not established from accessed source.
providers
Not established from accessed source.
assessors
Not established from accessed source.
analysts
Not established from accessed source.
population
relation
direct
population
63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
exposure Evidence
63 women and one man with prior IPV and at least moderate mental-health problems; ongoing IPV was an exclusion.
rationale
Explicit domestic/intimate-partner violence exposure in the studied population; psychological intervention is within Language scope.
transfer Limit
See limitation and quality fields; no population-wide clinical recommendation is implied.
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    anxiety
    evidence
    1. field
      outcomes
      text
      PTSD, IES-R | Depression, BDI-II | PDS, PHQ-9, anxiety and quality of life
      matched Text
      anxiety
    scope
    Study population or investigated outcome; not a diagnosis or efficacy claim.
  2. id
    ptsd
    evidence
    1. field
      outcomes
      text
      PTSD, IES-R | Depression, BDI-II | PDS, PHQ-9, anxiety and quality of life
      matched Text
      PTSD
    scope
    Study population or investigated outcome; not a diagnosis or efficacy claim.
  3. id
    depression
    evidence
    1. field
      outcomes
      text
      PTSD, IES-R | Depression, BDI-II | PDS, PHQ-9, anxiety and quality of life
      matched Text
      Depression
    scope
    Study population or investigated outcome; not a diagnosis or efficacy claim.
conditions

anxiety · ptsd · depression

topic Trust Scores

2

full Text
status
not-indexed
retrieval Available
false

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