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Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.

Cohen JA; Mannarino AP; Iyengar S · Archives of pediatrics & adolescent medicine · 2011 · Randomized controlled trial with blinded outcome evaluators

Original publication · Original publication · Original publication · Original publication

Recorded summary

TF-CBT improved PTSD and anxiety more than child-centered therapy; benefits did not extend clearly to depression or general behavior problems.

Recorded limitations

Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial with blinded outcome evaluators
assessment
category
rct
is Randomized Controlled Trial
true
basis
Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
sources

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

review Scope
selected-methods
trust Factor
scope
Paper
status
assessed
score
2
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
basis
Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
sources

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

review Scope
selected-methods
human Approval
false
display Crosses
2
masking Roles
participants
Aware of allocation.
providers
Aware of allocation.
assessors
Project coordinator/evaluators blinded.
analysts
Principal investigator aware; analyst masking not established.
rating Scale
library-trust-factor/1-3
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial with blinded outcome evaluators
intervention
Trauma-focused cognitive behavioral therapy (TF-CBT) Eight weekly sessions: 45 minutes each for child and mother, with joint portions in two sessions.
comparator
Child-centered therapy, the usual community treatment.
sample
Reported cohort/enrollment: 124. Analyzed/interviewed: 124.
measurement
Interview-rated total PTSD symptoms; Depression and total behavior problems
timing
After eight-session treatment; Post-treatment
trial Id
NCT00183326
relationship Note
Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence. Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
measured Genes
None recorded
pathways
None recorded
source Access
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

retrieved At
2026-10-30T07:25:30.543090+00:00
outcomes
  1. name
    Interview-rated total PTSD symptoms
    follow Up
    After eight-session treatment
    result
    Favored TF-CBT.
    effect Estimate
    mean Difference
    1.63
    CI95

    0.44 · 2.82

    analysis
    ITT with last observation carried forward; positive difference favors TF-CBT
    uncertainty
    Multiple imputation supported total PTSD improvement.
    primary Status
    Primary
  2. name
    Depression and total behavior problems
    follow Up
    Post-treatment
    result
    Between-group differences were not statistically significant.
    effect Estimate
    Not recorded
    uncertainty
    Confidence intervals included no difference.
    primary Status
    Secondary
quality
risk Of Bias
Important concerns: Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.
attrition
49/124 did not complete:18 before initial treatment and 31 during treatment.
confounding
Allocation, adherence, co-interventions and reporting limitations require consideration; see design and limitations.
adverse Findings
Fewer serious adverse events were reported among TF-CBT completers; this comparison is vulnerable to attrition.
transfer Limits
Do not extrapolate beyond the described population and intervention.
jadad
not established
masking Roles
participants
Aware of allocation.
providers
Aware of allocation.
assessors
Project coordinator/evaluators blinded.
analysts
Principal investigator aware; analyst masking not established.
population
relation
direct
population
Children with IPV-related PTSD symptoms and their mothers who were direct IPV victims.
exposure Evidence
Eligibility required at least five IPV-related PTSD symptoms and an IPV-victimized mother.
rationale
Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence.
transfer Limit
Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
Topics and recorded topic scores
  1. key
    language:domestic-family-violence
    title
    Domestic & Family Violence
    collection
    language
    trust Score
    2
Citation snapshot and identifiers
id
dv-children-21199975
doi
10.1001/archpediatrics.2010.247
pmid
21199975
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
language
Not recorded
Complete approved library record
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-01
assessment
AI assessed; human approved for publication
scope
Qualified research-library summaries. No professional clinical peer review or treatment recommendation is claimed.
source Revision
audit-r2-ebb52ba2c40f
source Content Hash
ebb52ba2c40fcef40023384ce3c9337d3b79e69d17ef3b372e8750dfa5bf1c4c
source Access
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

retrieved At
2026-10-30T07:25:30.543090+00:00
editorial Audit
auditor
Codex (AI)
completed At
2026-10-31T05:11:05.655793+00:00
prior Content Hash
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prior Revision
r1-e7bf7d29f3e7
prior Source
frozen-120
source Verification
id
dv-children-21199975
doi
10.1001/archpediatrics.2010.247
pmid
21199975
fresh Metadata
Europe PMC core
metadata Retrieved
true
metadata SHA256
868059c5c5146e08e28449fc6b9163c62fbc0b2ed9c21aee91e03939ec2c70b4
claim Check
Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
sources

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

applied Proposals
None recorded
method
AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
limitations

Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

study Family Id
NCT00183326
family Linkage Uncertain
false
approaches
None recorded
id
dv-children-21199975
aliases
None recorded
title
Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.
journal
Archives of pediatrics & adolescent medicine
neurotransmitters
None recorded
year
2011
authors
Cohen JA; Mannarino AP; Iyengar S
design
Randomized controlled trial with blinded outcome evaluators
kind
Journal article
identity Conflict
Not recorded
doi
10.1001/archpediatrics.2010.247
pmid
21199975
urls

https://doi.org/10.1001/archpediatrics.2010.247 · https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

collections

language

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
TF-CBT improved PTSD and anxiety more than child-centered therapy; benefits did not extend clearly to depression or general behavior problems.
limitation
Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
rct
is Randomized Controlled Trial
true
basis
Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
sources

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

review Scope
selected-methods
paper Trust Assessment
scope
Paper
status
assessed
score
2
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
basis
Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
sources

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

review Scope
selected-methods
human Approval
false
display Crosses
2
masking Roles
participants
Aware of allocation.
providers
Aware of allocation.
assessors
Project coordinator/evaluators blinded.
analysts
Principal investigator aware; analyst masking not established.
rating Scale
library-trust-factor/1-3
citations By Collection
language
Not recorded
topics
  1. key
    language:domestic-family-violence
    title
    Domestic & Family Violence
    collection
    language
    trust Score
    2
journal Key
archivesofpediatricsandadolescentmedicine
journal Label
Archives of pediatrics & adolescent medicine
chapter Entries
  1. id
    language-dv-dv-children-21199975
    aliases
    None recorded
    title
    Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.
    authors
    Cohen JA; Mannarino AP; Iyengar S
    year
    2011
    journal
    Archives of pediatrics & adolescent medicine
    doi
    10.1001/archpediatrics.2010.247
    pmid
    21199975
    urls

    https://doi.org/10.1001/archpediatrics.2010.247 · https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    collections

    language

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    ptsd · trauma · depression

    condition Evidence
    1. id
      ptsd
      evidence
      1. field
        title
        text
        Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.
        matched Text
        posttraumatic stress
      2. field
        population
        text
        Children with IPV-related PTSD symptoms and their mothers who were direct IPV victims.
        matched Text
        PTSD
      3. field
        outcomes
        text
        Interview-rated total PTSD symptoms | Depression and total behavior problems
        matched Text
        PTSD
      scope
      Study population or investigated outcome; not a diagnosis or efficacy claim.
    2. id
      trauma
      evidence
      1. field
        title
        text
        Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.
        matched Text
        posttraumatic
      scope
      Study population or investigated outcome; not a diagnosis or efficacy claim.
    3. id
      depression
      evidence
      1. field
        outcomes
        text
        Interview-rated total PTSD symptoms | Depression and total behavior problems
        matched Text
        Depression
      scope
      Study population or investigated outcome; not a diagnosis or efficacy claim.
    age Groups

    children · adolescents · youth

    age Population
    record Id
    dv-children-21199975
    collections

    language

    groups

    children · adolescents · youth

    reported Ages
    7–14 years
    youth Scope
    focus
    youth Source Note
    focus
    source URL
    https://pubmed.ncbi.nlm.nih.gov/21199975/
    basis Type
    source-limited-ai-editorial-assessment
    classification Note
    Original age terms: children, adolescents, youth. Programme targets or possible eligibility are not counted as observed ages.
    community Matches
    1. category Id
      domestic-violence
      relation
      direct
    kind
    Journal article
    design
    Randomized controlled trial with blinded outcome evaluators
    origin
    approved-dv-20261101
    priority
    1
    quotes
    None recorded
    finding
    TF-CBT improved PTSD and anxiety more than child-centered therapy; benefits did not extend clearly to depression or general behavior problems.
    summary
    TF-CBT improved PTSD and anxiety more than child-centered therapy; benefits did not extend clearly to depression or general behavior problems.
    limitation
    Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.
    evidence
    evidence Type
    Randomized controlled trial with blinded outcome evaluators
    intervention
    Trauma-focused cognitive behavioral therapy (TF-CBT) Eight weekly sessions: 45 minutes each for child and mother, with joint portions in two sessions.
    comparator
    Child-centered therapy, the usual community treatment.
    sample
    Reported cohort/enrollment: 124. Analyzed/interviewed: 124.
    measurement
    Interview-rated total PTSD symptoms; Depression and total behavior problems
    timing
    After eight-session treatment; Post-treatment
    trial Id
    NCT00183326
    relationship Note
    Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence. Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
    measured Genes
    None recorded
    pathways
    None recorded
    source Access
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    retrieved At
    2026-10-30T07:25:30.543090+00:00
    outcomes
    1. name
      Interview-rated total PTSD symptoms
      follow Up
      After eight-session treatment
      result
      Favored TF-CBT.
      effect Estimate
      mean Difference
      1.63
      CI95

      0.44 · 2.82

      analysis
      ITT with last observation carried forward; positive difference favors TF-CBT
      uncertainty
      Multiple imputation supported total PTSD improvement.
      primary Status
      Primary
    2. name
      Depression and total behavior problems
      follow Up
      Post-treatment
      result
      Between-group differences were not statistically significant.
      effect Estimate
      Not recorded
      uncertainty
      Confidence intervals included no difference.
      primary Status
      Secondary
    quality
    risk Of Bias
    Important concerns: Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.
    attrition
    49/124 did not complete:18 before initial treatment and 31 during treatment.
    confounding
    Allocation, adherence, co-interventions and reporting limitations require consideration; see design and limitations.
    adverse Findings
    Fewer serious adverse events were reported among TF-CBT completers; this comparison is vulnerable to attrition.
    transfer Limits
    Do not extrapolate beyond the described population and intervention.
    jadad
    not established
    masking Roles
    participants
    Aware of allocation.
    providers
    Aware of allocation.
    assessors
    Project coordinator/evaluators blinded.
    analysts
    Principal investigator aware; analyst masking not established.
    population
    relation
    direct
    population
    Children with IPV-related PTSD symptoms and their mothers who were direct IPV victims.
    exposure Evidence
    Eligibility required at least five IPV-related PTSD symptoms and an IPV-victimized mother.
    rationale
    Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence.
    transfer Limit
    Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
    study Design Assessment
    category
    rct
    is Randomized Controlled Trial
    true
    basis
    Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
    sources

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    review Scope
    selected-methods
    paper Trust Assessment
    scope
    Paper
    status
    assessed
    score
    2
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    basis
    Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
    sources

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    review Scope
    selected-methods
    human Approval
    false
    display Crosses
    2
    masking Roles
    participants
    Aware of allocation.
    providers
    Aware of allocation.
    assessors
    Project coordinator/evaluators blinded.
    analysts
    Principal investigator aware; analyst masking not established.
    rating Scale
    library-trust-factor/1-3
    jadad
    status
    unassessed
    score
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    citation Count
    Not recorded
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-01
    assessment
    AI assessed; human approved for publication
    scope
    Qualified research-library summaries. No professional clinical peer review or treatment recommendation is claimed.
    source Revision
    audit-r2-ebb52ba2c40f
    source Content Hash
    ebb52ba2c40fcef40023384ce3c9337d3b79e69d17ef3b372e8750dfa5bf1c4c
    source Access
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    retrieved At
    2026-10-30T07:25:30.543090+00:00
    study Family Id
    NCT00183326
    family Linkage Uncertain
    false
    approaches
    None recorded
    record Id
    dv-children-21199975
    source Pages
    None recorded
    editorial Audit
    auditor
    Codex (AI)
    completed At
    2026-10-31T05:11:05.655793+00:00
    prior Content Hash
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    source Verification
    id
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    doi
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    pmid
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    fresh Metadata
    Europe PMC core
    metadata Retrieved
    true
    metadata SHA256
    868059c5c5146e08e28449fc6b9163c62fbc0b2ed9c21aee91e03939ec2c70b4
    claim Check
    Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
    sources

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    applied Proposals
    None recorded
    method
    AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
    limitations

    Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

    assessment Record
    id
    dv-children-21199975
    title
    Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.
    authors

    Cohen JA · Mannarino AP · Iyengar S

    year
    2011
    journal
    Archives of pediatrics & adolescent medicine
    doi
    10.1001/archpediatrics.2010.247
    pmid
    21199975
    trial Registration

    NCT00183326

    collection
    language
    intervention Family
    Trauma-focused cognitive behavioral therapy (TF-CBT)
    publication Type
    Randomized controlled trial with blinded outcome evaluators
    study Family Id
    NCT00183326
    family Linkage Uncertain
    false
    linked Publication PMIDs
    None recorded
    existing Repository Matches
    None recorded
    relevance
    relation
    direct
    population
    Children with IPV-related PTSD symptoms and their mothers who were direct IPV victims.
    exposure Evidence
    Eligibility required at least five IPV-related PTSD symptoms and an IPV-victimized mother.
    rationale
    Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence.
    transfer Limit
    Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
    age
    groups

    children · adolescents · youth

    reported Range
    7–14 years
    youth Scope
    focus
    country
    United States
    setting
    Community intimate-partner-violence center, Pittsburgh
    sample Size
    randomized
    124
    analyzed
    124
    description
    Reported cohort/enrollment: 124. Analyzed/interviewed: 124.
    intervention
    description
    Trauma-focused cognitive behavioral therapy (TF-CBT)
    dose
    Eight weekly sessions: 45 minutes each for child and mother, with joint portions in two sessions.
    provider
    Three trained master’s-level social workers.
    comparator
    Child-centered therapy, the usual community treatment.
    outcomes
    1. name
      Interview-rated total PTSD symptoms
      follow Up
      After eight-session treatment
      result
      Favored TF-CBT.
      effect Estimate
      mean Difference
      1.63
      CI95

      0.44 · 2.82

      analysis
      ITT with last observation carried forward; positive difference favors TF-CBT
      uncertainty
      Multiple imputation supported total PTSD improvement.
      primary Status
      Primary
    2. name
      Depression and total behavior problems
      follow Up
      Post-treatment
      result
      Between-group differences were not statistically significant.
      effect Estimate
      Not recorded
      uncertainty
      Confidence intervals included no difference.
      primary Status
      Secondary
    finding
    TF-CBT improved PTSD and anxiety more than child-centered therapy; benefits did not extend clearly to depression or general behavior problems.
    limitation
    Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.
    design
    type
    Randomized controlled trial with blinded outcome evaluators
    randomization Evidence
    Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
    masking
    participants
    Aware of allocation.
    providers
    Aware of allocation.
    assessors
    Project coordinator/evaluators blinded.
    analysts
    Principal investigator aware; analyst masking not established.
    crosses
    1
    cross Rationale
    Randomized allocation is explicitly supported; double blinding is not established.
    quality
    risk Of Bias
    Important concerns: Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.
    attrition
    49/124 did not complete:18 before initial treatment and 31 during treatment.
    confounding
    Allocation, adherence, co-interventions and reporting limitations require consideration; see design and limitations.
    adverse Findings
    Fewer serious adverse events were reported among TF-CBT completers; this comparison is vulnerable to attrition.
    transfer Limits
    Do not extrapolate beyond the described population and intervention.
    jadad
    not established
    access
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    retrieved At
    2026-10-30T07:25:30.543090+00:00
    sources
    1. url
      https://pubmed.ncbi.nlm.nih.gov/21199975/
      type
      PubMed XML bibliographic/abstract record
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      2026-10-30T07:25:30.543090+00:00
      identity Verified
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      notes
      Title and PMID matched between Europe PMC core metadata and PubMed XML; DOI, authors and journal metadata retained.
    2. url
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      type
      Europe PMC core bibliographic/abstract record
      retrieved At
      2026-10-30T07:25:30.543090+00:00
      identity Verified
      true
      notes
      Title and PMID matched between Europe PMC core metadata and PubMed XML; DOI, authors and journal metadata retained.
    3. url
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      type
      journal full text: selected methods/results
      retrieved At
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      identity Verified
      true
      notes
      Title and PMID matched between Europe PMC core metadata and PubMed XML; DOI, authors and journal metadata retained.
    publication Status
    status
    Published journal report; no retraction/erratum relationship flagged in retrieved PubMed record.
    correction Retraction Check
    method
    Inspected PubMed publication types and CommentsCorrections relationships plus Europe PMC metadata.
    relationships
    1. type
      CommentIn
      pmid
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    checked At
    2026-10-30T07:25:30.543090+00:00
    uncertainty
    Index metadata can lag; publisher Crossmark and trial-register reconciliation are not comprehensively verified.
    recommendation Rationale
    Adds controlled child/family treatment evidence; consider as a new candidate after human review.
    review
    status
    pending
    reviewer
    Not recorded
    assessment Status
    assessed
    assessment Notes
    Source-supported assessment with visible access limits; not a completed human approval or formal risk-of-bias instrument. This report does not represent an additional independent study when its family ID is shared.
    research Lane
    children
    review Ready
    true
    review Readiness
    ai-editorial-audit-complete-release-pending
    publication Recommendation
    status
    recommended-summary
    reason
    Suitable as a qualified research-library summary at the stated source-access level. This is not a conclusion that the intervention is effective or safe.
    scope
    Research summary only; no treatment recommendation
    human Release Approval
    false
    editorial Audit
    auditor
    Codex (AI)
    completed At
    2026-10-31T05:11:05.655793+00:00
    prior Content Hash
    e7bf7d29f3e721fe5d85f79503e8b12bde4dd331e6ae930373d08f425aadfd6a
    prior Revision
    r1-e7bf7d29f3e7
    prior Source
    frozen-120
    source Verification
    id
    dv-children-21199975
    doi
    10.1001/archpediatrics.2010.247
    pmid
    21199975
    fresh Metadata
    Europe PMC core
    metadata Retrieved
    true
    metadata SHA256
    868059c5c5146e08e28449fc6b9163c62fbc0b2ed9c21aee91e03939ec2c70b4
    claim Check
    Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
    sources

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    applied Proposals
    None recorded
    method
    AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
    limitations

    Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.

    study Design Assessment
    category
    rct
    is Randomized Controlled Trial
    true
    basis
    Computer-generated random numbers; 24 sibling sets shared the first sibling’s allocation.
    sources

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    review Scope
    selected-methods
    paper Trust Assessment
    scope
    Paper
    status
    assessed
    score
    2
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    basis
    Randomized allocation is explicitly supported; double blinding is not established.
    sources

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    review Scope
    selected-methods
    human Approval
    false
    display Crosses
    1
    masking Roles
    participants
    Aware of allocation.
    providers
    Aware of allocation.
    assessors
    Project coordinator/evaluators blinded.
    analysts
    Principal investigator aware; analyst masking not established.
    jadad
    status
    unassessed
    score
    Not recorded
    evidence
    population
    relation
    direct
    population
    Children with IPV-related PTSD symptoms and their mothers who were direct IPV victims.
    exposure Evidence
    Eligibility required at least five IPV-related PTSD symptoms and an IPV-victimized mother.
    rationale
    Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence.
    transfer Limit
    Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
    intervention
    description
    Trauma-focused cognitive behavioral therapy (TF-CBT)
    dose
    Eight weekly sessions: 45 minutes each for child and mother, with joint portions in two sessions.
    provider
    Three trained master’s-level social workers.
    comparator
    Child-centered therapy, the usual community treatment.
    outcomes
    1. name
      Interview-rated total PTSD symptoms
      follow Up
      After eight-session treatment
      result
      Favored TF-CBT.
      effect Estimate
      mean Difference
      1.63
      CI95

      0.44 · 2.82

      analysis
      ITT with last observation carried forward; positive difference favors TF-CBT
      uncertainty
      Multiple imputation supported total PTSD improvement.
      primary Status
      Primary
    2. name
      Depression and total behavior problems
      follow Up
      Post-treatment
      result
      Between-group differences were not statistically significant.
      effect Estimate
      Not recorded
      uncertainty
      Confidence intervals included no difference.
      primary Status
      Secondary
    access
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

    retrieved At
    2026-10-30T07:25:30.543090+00:00
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    provenance
    Discovered by AI
    content Hash
    ebb52ba2c40fcef40023384ce3c9337d3b79e69d17ef3b372e8750dfa5bf1c4c
    revision
    audit-r2-ebb52ba2c40f
    archive Entries
    None recorded
    collection
    language
    chapter Number
    5
    topic Id
    domestic-family-violence
    topic Title
    Domestic & Family Violence
    trust Score
    2
evidence
evidence Type
Randomized controlled trial with blinded outcome evaluators
intervention
Trauma-focused cognitive behavioral therapy (TF-CBT) Eight weekly sessions: 45 minutes each for child and mother, with joint portions in two sessions.
comparator
Child-centered therapy, the usual community treatment.
sample
Reported cohort/enrollment: 124. Analyzed/interviewed: 124.
measurement
Interview-rated total PTSD symptoms; Depression and total behavior problems
timing
After eight-session treatment; Post-treatment
trial Id
NCT00183326
relationship Note
Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence. Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
measured Genes
None recorded
pathways
None recorded
source Access
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/21199975/ · https://europepmc.org/article/MED/21199975 · https://jamanetwork.com/journals/jamapediatrics/fullarticle/384142

retrieved At
2026-10-30T07:25:30.543090+00:00
outcomes
  1. name
    Interview-rated total PTSD symptoms
    follow Up
    After eight-session treatment
    result
    Favored TF-CBT.
    effect Estimate
    mean Difference
    1.63
    CI95

    0.44 · 2.82

    analysis
    ITT with last observation carried forward; positive difference favors TF-CBT
    uncertainty
    Multiple imputation supported total PTSD improvement.
    primary Status
    Primary
  2. name
    Depression and total behavior problems
    follow Up
    Post-treatment
    result
    Between-group differences were not statistically significant.
    effect Estimate
    Not recorded
    uncertainty
    Confidence intervals included no difference.
    primary Status
    Secondary
quality
risk Of Bias
Important concerns: Only 75 of 124 completed treatment; missing outcomes required imputation. Siblings shared allocation. No long-term outcome is established here.
attrition
49/124 did not complete:18 before initial treatment and 31 during treatment.
confounding
Allocation, adherence, co-interventions and reporting limitations require consideration; see design and limitations.
adverse Findings
Fewer serious adverse events were reported among TF-CBT completers; this comparison is vulnerable to attrition.
transfer Limits
Do not extrapolate beyond the described population and intervention.
jadad
not established
masking Roles
participants
Aware of allocation.
providers
Aware of allocation.
assessors
Project coordinator/evaluators blinded.
analysts
Principal investigator aware; analyst masking not established.
population
relation
direct
population
Children with IPV-related PTSD symptoms and their mothers who were direct IPV victims.
exposure Evidence
Eligibility required at least five IPV-related PTSD symptoms and an IPV-victimized mother.
rationale
Direct study of a therapeutic intervention, its follow-up, or service engagement in children/families affected by domestic or interparental violence.
transfer Limit
Population and setting are specific; no inference of effectiveness for all survivors, ages or violence contexts.
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    ptsd
    evidence
    1. field
      title
      text
      Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.
      matched Text
      posttraumatic stress
    2. field
      population
      text
      Children with IPV-related PTSD symptoms and their mothers who were direct IPV victims.
      matched Text
      PTSD
    3. field
      outcomes
      text
      Interview-rated total PTSD symptoms | Depression and total behavior problems
      matched Text
      PTSD
    scope
    Study population or investigated outcome; not a diagnosis or efficacy claim.
  2. id
    trauma
    evidence
    1. field
      title
      text
      Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial.
      matched Text
      posttraumatic
    scope
    Study population or investigated outcome; not a diagnosis or efficacy claim.
  3. id
    depression
    evidence
    1. field
      outcomes
      text
      Interview-rated total PTSD symptoms | Depression and total behavior problems
      matched Text
      Depression
    scope
    Study population or investigated outcome; not a diagnosis or efficacy claim.
conditions

ptsd · trauma · depression

topic Trust Scores

2

full Text
status
not-indexed
retrieval Available
false

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