Psychological intervention in women victims of childhood sexual abuse: a randomized controlled clinical trial comparing EMDR psychotherapy and trauma-focused cognitive behavioral therapy.
Milagros Molero-Zafra; Olga Fernández-García; María Teresa Mitjans-Lafont; Marián Pérez-Marín; María Jesús Hernández-Jiménez · Frontiers in Psychiatry · 2024 · Randomized active-comparator trial
Original publication · Original publication · Original publication · Original publication · Original publication
Recorded summary
No significant between-group differences were found; within-group changes varied by symptom.
Recorded limitations
Small completer analysis and no long-term follow-up; nonsignificant differences do not prove equivalence.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
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- comparator
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- sample
- 19 women in first-phase analysis; later report identifies 31 eligible recruits.
- measurement
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- timing
- immediately after treatment
- trial Id
- NCT04813224
- relationship Note
- Childhood interpersonal abuse may overlap family violence and informs adult trauma treatment. Family/partner perpetration is not established for the whole sample; do not label this an adult IPV trial.
- measured Genes
- None recorded
- pathways
- None recorded
- source Access
- level
- full-text
- source URLs
https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML
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- outcomes
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- quality
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- Tiny completer sample, multiple tests, no untreated control.
- attrition
- Analysis required at least six of eight sessions; later family report confirms substantial attrition.
- confounding
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- Adult clinical samples do not establish benefit for children or violence prevention.
- jadad
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- assessors
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- CSA was required; familial relationship of perpetrators is not established in the accessed report.
- rationale
- Childhood interpersonal abuse may overlap family violence and informs adult trauma treatment.
- transfer Limit
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Topics and recorded topic scores
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Complete approved library record
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
- applied Proposals
- None recorded
- method
- AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
- limitations
Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.
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- title
- Psychological intervention in women victims of childhood sexual abuse: a randomized controlled clinical trial comparing EMDR psychotherapy and trauma-focused cognitive behavioral therapy.
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- Frontiers in Psychiatry
- neurotransmitters
- None recorded
- year
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- authors
- Milagros Molero-Zafra; Olga Fernández-García; María Teresa Mitjans-Lafont; Marián Pérez-Marín; María Jesús Hernández-Jiménez
- design
- Randomized active-comparator trial
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- Not recorded
- doi
- 10.3389/fpsyt.2024.1360388
- pmid
- 38868491
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https://doi.org/10.3389/fpsyt.2024.1360388 · https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
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- limitation
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
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- Psychological intervention in women victims of childhood sexual abuse: a randomized controlled clinical trial comparing EMDR psychotherapy and trauma-focused cognitive behavioral therapy.
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- relationship Note
- Childhood interpersonal abuse may overlap family violence and informs adult trauma treatment. Family/partner perpetration is not established for the whole sample; do not label this an adult IPV trial.
- measured Genes
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML
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- jadad
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- CSA was required; familial relationship of perpetrators is not established in the accessed report.
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
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- applied Proposals
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- method
- AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
- limitations
Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.
- assessment Record
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- title
- Psychological intervention in women victims of childhood sexual abuse: a randomized controlled clinical trial comparing EMDR psychotherapy and trauma-focused cognitive behavioral therapy.
- authors
Milagros Molero-Zafra · Olga Fernández-García · María Teresa Mitjans-Lafont · Marián Pérez-Marín · María Jesús Hernández-Jiménez
- year
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- journal
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- pmid
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NCT04813224
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- exposure Evidence
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- rationale
- Childhood interpersonal abuse may overlap family violence and informs adult trauma treatment.
- transfer Limit
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adults · youth
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- description
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- intervention
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- EMDR group traumatic-episode protocol via Zoom
- dose
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- outcomes
- name
- PTSD, dissociation, psychopathology and quality-of-life measures
- follow Up
- immediately after treatment
- result
- No significant post-treatment arm differences; some within-arm improvements, several null outcomes.
- effect Estimate
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- uncertainty
- not established from accessed source
- primary Status
- not established from accessed source
- finding
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- limitation
- Small completer analysis and no long-term follow-up; nonsignificant differences do not prove equivalence.
- design
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- Permuted blocks generated with Randomizer.org; assignment followed enrollment order.
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- assessors
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- confounding
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- transfer Limits
- Adult clinical samples do not establish benefit for children or violence prevention.
- jadad
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML
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- Title, DOI and authors reconciled across primary abstract or publisher-deposited metadata.
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- https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full
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- 2026-10-30T07:22:28.727073+00:00
- identity Verified
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- Source directly inspected for the extracted claims.
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- 2026-10-30T07:22:28.727073+00:00
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- Title/authors/DOI matched; update-to and relation fields checked.
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- Crossref publisher-deposited update-to and relation fields were empty on 30 October 2026; no correction/retraction notice was identified in accessed metadata. This limited check cannot exclude unlinked notices. Europe PMC publication types and available correction/comment fields were also inspected; no retraction type or notice was present.
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- Retain as pending evidence for human review, with design and source-access limits visible.
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- pending
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- assessment Notes
Clinical EMDR evidence concerns a therapist-delivered multicomponent treatment; it does not isolate eye movements or validate standalone audiovisual content. · The later same-family 2026 paper describes CSA as frequently intrafamilial, but exact perpetrator proportions for this 19-person first-phase sample are not established.
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- Suitable as a qualified research-library summary at the stated source-access level. This is not a conclusion that the intervention is effective or safe.
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- 10.3389/fpsyt.2024.1360388
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- claim Check
- Headline finding/design/limitations compared with indexed abstract or accessible primary evidence; retained methods amendments separately adjudicated.
- sources
https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
- applied Proposals
- None recorded
- method
- AI editorial assessment of all 130 publication records: compare identity, headline finding, design, relevance and limitations with indexed abstracts or available primary material; adjudicate retained source-supported methods amendments. This is a source-limited publication audit, not an independent full-text systematic review or a clinical guideline.
- limitations
Abstract-only records do not establish allocation concealment, complete harms reporting or full risk of bias. · No formal independent RoB 2, GRADE appraisal or numerical reconstruction of every effect was performed. · Source-access labels describe retained appraisal evidence; fuller prior appraisals were checked through their source ledgers and selected material, not independently repeated in full. · Publication counts are not independent trial or participant counts; cohort links and overlapping review evidence remain provisional. · A randomized design cross does not indicate benefit, low risk of bias or human approval. No double-blind trial is verified in this release. · No professional clinical peer review is claimed. Recommended content is limited to accurately qualified research summaries.
- study Design Assessment
- category
- rct
- is Randomized Controlled Trial
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- basis
- Permuted blocks generated with Randomizer.org; assignment followed enrollment order.
- sources
https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
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- 2
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- One cross: randomized assignment verified; therapists knew treatment, so double blinding not established.
- sources
https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyt.2024.1360388
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- Adult women with childhood sexual abuse
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- CSA was required; familial relationship of perpetrators is not established in the accessed report.
- rationale
- Childhood interpersonal abuse may overlap family violence and informs adult trauma treatment.
- transfer Limit
- Family/partner perpetration is not established for the whole sample; do not label this an adult IPV trial.
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- EMDR group traumatic-episode protocol via Zoom
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- Eight weekly approximately 60-minute sessions; groups of 2–4.
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- Online group trauma-focused CBT.
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- immediately after treatment
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- No significant post-treatment arm differences; some within-arm improvements, several null outcomes.
- effect Estimate
- not established from accessed source
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https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML
- retrieved At
- 2026-10-30T07:22:28.727073+00:00
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- Discovered by AI
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- 7
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- domestic-family-violence
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- Domestic & Family Violence
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- 2
- evidence
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- Randomized active-comparator trial
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- EMDR group traumatic-episode protocol via Zoom Eight weekly approximately 60-minute sessions; groups of 2–4.
- comparator
- Online group trauma-focused CBT.
- sample
- 19 women in first-phase analysis; later report identifies 31 eligible recruits.
- measurement
- PTSD, dissociation, psychopathology and quality-of-life measures
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- immediately after treatment
- trial Id
- NCT04813224
- relationship Note
- Childhood interpersonal abuse may overlap family violence and informs adult trauma treatment. Family/partner perpetration is not established for the whole sample; do not label this an adult IPV trial.
- measured Genes
- None recorded
- pathways
- None recorded
- source Access
- level
- full-text
- source URLs
https://pubmed.ncbi.nlm.nih.gov/38868491/ · https://doi.org/10.3389/fpsyt.2024.1360388 · https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1360388/full · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11167727/fullTextXML
- retrieved At
- 2026-10-30T07:22:28.727073+00:00
- outcomes
- name
- PTSD, dissociation, psychopathology and quality-of-life measures
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- immediately after treatment
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- No significant post-treatment arm differences; some within-arm improvements, several null outcomes.
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- not established from accessed source
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- not established from accessed source
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- not established from accessed source
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- Tiny completer sample, multiple tests, no untreated control.
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- Analysis required at least six of eight sessions; later family report confirms substantial attrition.
- confounding
- not established from accessed source
- adverse Findings
- not established from accessed source
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- Adult clinical samples do not establish benefit for children or violence prevention.
- jadad
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- Not informed of both conditions or allocation procedures; effective masking uncertain.
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- Aware of both protocols.
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- Adult women with childhood sexual abuse
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- CSA was required; familial relationship of perpetrators is not established in the accessed report.
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- Childhood interpersonal abuse may overlap family violence and informs adult trauma treatment.
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- Family/partner perpetration is not established for the whole sample; do not label this an adult IPV trial.
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ptsd
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2
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