Watching gene expression in color.
Simpson JH. · eLife · 2019 · Journal publication
Original publication · Original publication · Original publication
Recorded summary
Reference associated with Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription.
Recorded limitations
Bibliographic metadata matched; scientific claims await appraisal.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Journal publication
- assessment
- Not recorded
- trust Factor
- scope
- Paper
- status
- unassessed
- score
- Not recorded
- basis
- Bibliographic identity checks do not establish study design, blinding or evidential strength.
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- general:autofluorescence-sensing
- title
- Autofluorescence and Molecular Sensing
- collection
- general
- trust Score
- Not recorded
Citation snapshot and identifiers
- id
- hsi-0d33d222d235dd
- doi
- 10.7554/elife.49414
- pmid
- 31348001
- citation Snapshot
- Not recorded
- citations By Collection
- general
- Not recorded
Complete approved library record
- id
- hsi-0d33d222d235dd
- aliases
- None recorded
- source References
- ref
- NPL-193
- record Id
- hsi-0d33d222d235dd
- source Type
- Journal publication
- title
- Watching gene expression in color.
- authors
- Simpson JH.
- year
- 2019
- journal
- eLife
- doi
- 10.7554/elife.49414
- pmid
- 31348001
- pmcid
- PMC6660214
- patent Number
- Not recorded
- original Assignee
- Not recorded
- original Citation
- Simpson CL (2019). "Transcriptional Reporters: Watching Gene Expression in Color." eLife 8:e49414 (PMC 6660214) — Insight on TransTimer dual-colour fluorescent transcriptional reporter; green-to-red colour shift encoding transcriptional history at single-cell resolution; protein translation as the mechanism linking gene transcription to visible fluorescence
- original Section
- Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription
- metadata Status
- metadata-reconciled
- claim Review
- Not independently appraised
- source URL
- https://www.notion.so/3807b9c99c5680599be7d8337c817b15
- publication URL
- https://pubmed.ncbi.nlm.nih.gov/31348001/
- metadata URL
- https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.7554%2FeLife.49414%22&format=json&resultType=core&pageSize=4
- corrections
Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison. · Published title reconciled with the metadata record.
- topic Id
- autofluorescence-sensing
- role
- Focused chapter source
- ref
- NPL-198
- record Id
- hsi-0d33d222d235dd
- source Type
- Journal publication
- title
- Watching gene expression in color.
- authors
- Simpson JH.
- year
- 2019
- journal
- eLife
- doi
- 10.7554/elife.49414
- pmid
- 31348001
- pmcid
- PMC6660214
- patent Number
- Not recorded
- original Assignee
- Not recorded
- original Citation
- Simpson CL (2019). "Watching Gene Expression in Color: TransTimer Dual-Colour Fluorescent Reporter." eLife 8:e49414 — TransTimer reporter system: slow-maturing green fluorescent protein and fast-maturing red fluorescent protein under same promoter; green/red ratio encodes time since transcriptional activation; real-time colour-coded visualisation of transcriptional history in living cells
- original Section
- Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription
- metadata Status
- metadata-reconciled
- claim Review
- Not independently appraised
- source URL
- https://www.notion.so/3807b9c99c5680599be7d8337c817b15
- publication URL
- https://pubmed.ncbi.nlm.nih.gov/31348001/
- metadata URL
- https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.7554%2FeLife.49414%22&format=json&resultType=core&pageSize=4
- corrections
Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison. · Published title reconciled with the metadata record.
- topic Id
- autofluorescence-sensing
- role
- Focused chapter source
- source Type
- Journal publication
- source Verification
- Bibliographic metadata matched; scientific claims await appraisal.
- source Collection
- Hyperspectral Imaging · patent section 2.4
- title
- Watching gene expression in color.
- journal
- eLife
- neurotransmitters
- None recorded
- year
- 2019
- authors
- Simpson JH.
- design
- Journal publication
- kind
- Journal publication
- identity Conflict
- Not recorded
- doi
- 10.7554/elife.49414
- pmid
- 31348001
- urls
https://pubmed.ncbi.nlm.nih.gov/31348001/ · https://doi.org/10.7554/elife.49414 · https://pmc.ncbi.nlm.nih.gov/articles/PMC6660214/
- collections
general
- categories
Hyperspectral Imaging
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- Reference associated with Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription.
- limitation
- Bibliographic metadata matched; scientific claims await appraisal.
- citation Count
- Not recorded
- paper Trust Assessment
- scope
- Paper
- status
- unassessed
- score
- Not recorded
- basis
- Bibliographic identity checks do not establish study design, blinding or evidential strength.
- citations By Collection
- general
- Not recorded
- topics
- key
- general:autofluorescence-sensing
- title
- Autofluorescence and Molecular Sensing
- collection
- general
- trust Score
- Not recorded
- journal Key
- elife
- journal Label
- eLife
- chapter Entries
- id
- general-autofluorescence-sensing-hsi-0d33d222d235dd
- record Id
- hsi-0d33d222d235dd
- title
- Watching gene expression in color.
- journal
- eLife
- year
- 2019
- authors
- Simpson JH.
- design
- Journal publication
- urls
https://pubmed.ncbi.nlm.nih.gov/31348001/ · https://doi.org/10.7554/elife.49414 · https://pmc.ncbi.nlm.nih.gov/articles/PMC6660214/
- quotes
- None recorded
- summary
- Reference associated with Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription.
- related Versions
- None recorded
- limitation
- Bibliographic metadata matched; scientific claims await appraisal.
- citation Count
- Not recorded
- source Pages
- None recorded
- doi
- 10.7554/elife.49414
- pmid
- 31348001
- targets
- None recorded
- categories
Hyperspectral Imaging
- source References
- ref
- NPL-193
- record Id
- hsi-0d33d222d235dd
- source Type
- Journal publication
- title
- Watching gene expression in color.
- authors
- Simpson JH.
- year
- 2019
- journal
- eLife
- doi
- 10.7554/elife.49414
- pmid
- 31348001
- pmcid
- PMC6660214
- patent Number
- Not recorded
- original Assignee
- Not recorded
- original Citation
- Simpson CL (2019). "Transcriptional Reporters: Watching Gene Expression in Color." eLife 8:e49414 (PMC 6660214) — Insight on TransTimer dual-colour fluorescent transcriptional reporter; green-to-red colour shift encoding transcriptional history at single-cell resolution; protein translation as the mechanism linking gene transcription to visible fluorescence
- original Section
- Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription
- metadata Status
- metadata-reconciled
- claim Review
- Not independently appraised
- source URL
- https://www.notion.so/3807b9c99c5680599be7d8337c817b15
- publication URL
- https://pubmed.ncbi.nlm.nih.gov/31348001/
- metadata URL
- https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.7554%2FeLife.49414%22&format=json&resultType=core&pageSize=4
- corrections
Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison. · Published title reconciled with the metadata record.
- topic Id
- autofluorescence-sensing
- role
- Focused chapter source
- ref
- NPL-198
- record Id
- hsi-0d33d222d235dd
- source Type
- Journal publication
- title
- Watching gene expression in color.
- authors
- Simpson JH.
- year
- 2019
- journal
- eLife
- doi
- 10.7554/elife.49414
- pmid
- 31348001
- pmcid
- PMC6660214
- patent Number
- Not recorded
- original Assignee
- Not recorded
- original Citation
- Simpson CL (2019). "Watching Gene Expression in Color: TransTimer Dual-Colour Fluorescent Reporter." eLife 8:e49414 — TransTimer reporter system: slow-maturing green fluorescent protein and fast-maturing red fluorescent protein under same promoter; green/red ratio encodes time since transcriptional activation; real-time colour-coded visualisation of transcriptional history in living cells
- original Section
- Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription
- metadata Status
- metadata-reconciled
- claim Review
- Not independently appraised
- source URL
- https://www.notion.so/3807b9c99c5680599be7d8337c817b15
- publication URL
- https://pubmed.ncbi.nlm.nih.gov/31348001/
- metadata URL
- https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI%3A%2210.7554%2FeLife.49414%22&format=json&resultType=core&pageSize=4
- corrections
Canonical title, authors, year and identifiers follow the linked public metadata record. The original citation is retained for comparison. · Published title reconciled with the metadata record.
- topic Id
- autofluorescence-sensing
- role
- Focused chapter source
- source Type
- Journal publication
- source Verification
- Bibliographic metadata matched; scientific claims await appraisal.
- collection
- general
- chapter Number
- 11
- topic Id
- autofluorescence-sensing
- topic Title
- Autofluorescence and Molecular Sensing
- trust Score
- Not recorded
- paper Trust Assessment
- scope
- Paper
- status
- unassessed
- score
- Not recorded
- basis
- Bibliographic identity checks do not establish study design, blinding or evidential strength.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- not-indexed
- retrieval Available
- false