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A protein-tagging system for signal amplification in gene expression and fluorescence imaging.

Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. · Cell · 2014 · Journal publication

Original publication · Original publication · Original publication

Recorded summary

Reference associated with Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription.

Recorded limitations

Bibliographic metadata matched; scientific claims await appraisal.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Journal publication
assessment
Not recorded
trust Factor
scope
Paper
status
unassessed
score
Not recorded
basis
Bibliographic identity checks do not establish study design, blinding or evidential strength.
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
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    general:autofluorescence-sensing
    title
    Autofluorescence and Molecular Sensing
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    general
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Citation snapshot and identifiers
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hsi-320858d8be27a8
doi
10.1016/j.cell.2014.09.039
pmid
25307933
citation Snapshot
Not recorded
citations By Collection
general
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Complete approved library record
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hsi-320858d8be27a8
aliases
None recorded
source References
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    title
    A protein-tagging system for signal amplification in gene expression and fluorescence imaging.
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    Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD.
    year
    2014
    journal
    Cell
    doi
    10.1016/j.cell.2014.09.039
    pmid
    25307933
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    original Assignee
    Not recorded
    original Citation
    Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD (2014). "A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging." Cell 159(3):635–646 — SunTag: repeating GCN4 peptide epitope array recruiting up to 24 copies of scFv-GFP fusion per translation event; single-molecule imaging of translation dynamics; amplifies fluorescent signal of individual protein translation events to single-molecule detectability
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    Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription
    metadata Status
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    https://www.notion.so/3807b9c99c5680599be7d8337c817b15
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    corrections
    None recorded
    topic Id
    autofluorescence-sensing
    role
    Focused chapter source
source Type
Journal publication
source Verification
Bibliographic metadata matched; scientific claims await appraisal.
source Collection
Hyperspectral Imaging · patent section 2.4
title
A protein-tagging system for signal amplification in gene expression and fluorescence imaging.
journal
Cell
neurotransmitters
None recorded
year
2014
authors
Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD.
design
Journal publication
kind
Journal publication
identity Conflict
Not recorded
doi
10.1016/j.cell.2014.09.039
pmid
25307933
urls

https://pubmed.ncbi.nlm.nih.gov/25307933/ · https://doi.org/10.1016/j.cell.2014.09.039 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4252608/

collections

general

categories

Hyperspectral Imaging

targets
None recorded
priority
1
quotes
None recorded
summary
Reference associated with Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription.
limitation
Bibliographic metadata matched; scientific claims await appraisal.
citation Count
Not recorded
paper Trust Assessment
scope
Paper
status
unassessed
score
Not recorded
basis
Bibliographic identity checks do not establish study design, blinding or evidential strength.
citations By Collection
general
Not recorded
topics
  1. key
    general:autofluorescence-sensing
    title
    Autofluorescence and Molecular Sensing
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    general
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    Not recorded
journal Key
cell
journal Label
Cell
chapter Entries
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    hsi-320858d8be27a8
    title
    A protein-tagging system for signal amplification in gene expression and fluorescence imaging.
    journal
    Cell
    year
    2014
    authors
    Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD.
    design
    Journal publication
    urls

    https://pubmed.ncbi.nlm.nih.gov/25307933/ · https://doi.org/10.1016/j.cell.2014.09.039 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4252608/

    quotes
    None recorded
    summary
    Reference associated with Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription.
    related Versions
    None recorded
    limitation
    Bibliographic metadata matched; scientific claims await appraisal.
    citation Count
    Not recorded
    source Pages
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    doi
    10.1016/j.cell.2014.09.039
    pmid
    25307933
    targets
    None recorded
    categories

    Hyperspectral Imaging

    source References
    1. ref
      NPL-195
      record Id
      hsi-320858d8be27a8
      source Type
      Journal publication
      title
      A protein-tagging system for signal amplification in gene expression and fluorescence imaging.
      authors
      Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD.
      year
      2014
      journal
      Cell
      doi
      10.1016/j.cell.2014.09.039
      pmid
      25307933
      pmcid
      PMC4252608
      patent Number
      Not recorded
      original Assignee
      Not recorded
      original Citation
      Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD (2014). "A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging." Cell 159(3):635–646 — SunTag: repeating GCN4 peptide epitope array recruiting up to 24 copies of scFv-GFP fusion per translation event; single-molecule imaging of translation dynamics; amplifies fluorescent signal of individual protein translation events to single-molecule detectability
      original Section
      Tryptophan Autofluorescence as a Primary Optical Marker of Gene Transcription
      metadata Status
      metadata-matched
      claim Review
      Not independently appraised
      source URL
      https://www.notion.so/3807b9c99c5680599be7d8337c817b15
      publication URL
      https://pubmed.ncbi.nlm.nih.gov/25307933/
      metadata URL
      https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22A+Protein-Tagging+System+for+Signal+Amplification+in+Gene+Expression+and+Fluorescence+Imaging%22&format=json&resultType=core&pageSize=4
      corrections
      None recorded
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      autofluorescence-sensing
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      Focused chapter source
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    Bibliographic metadata matched; scientific claims await appraisal.
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    general
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    trust Score
    Not recorded
    paper Trust Assessment
    scope
    Paper
    status
    unassessed
    score
    Not recorded
    basis
    Bibliographic identity checks do not establish study design, blinding or evidential strength.
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores
None recorded
full Text
status
not-indexed
retrieval Available
false

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