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Discovery of spatial pattern of prickles on stem of Rosa hybrida ‘Red Queen’ and mathematical model of the pattern

Kazuaki Amikura; Hiroshi Ito; Miho S. Kitazawa · Scientific Reports · 2021 · Plant morphology measurements and mathematical model

Original publication · Original publication · Original publication

Recorded summary

Rose stems show a non-random distribution of prickles relative to spiral leaf phyllotaxis. A diffusion-based inhibition model reproduces the measured pattern and selected patterns in other plants.

Recorded limitations

The primary measurements cover nine shoots of one rose cultivar. The model assumes a patterning process; the responsible inhibitory factors and broader applicability remain unresolved.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Plant morphology measurements and mathematical model
assessment
is Randomized Controlled Trial
false
blinding
Not applicable to a clinical-trial grade
basis
Plant morphology measurements and mathematical model. No human randomized controlled trial is reported.
sources

https://www.nature.com/articles/s41598-021-93133-8

category
peer-reviewed
peer Reviewed
true
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-confirmed
peer Reviewed
true
basis
Plant morphology measurements and mathematical model. No human randomized controlled trial is reported.
sources

https://pubmed.ncbi.nlm.nih.gov/34226577/ · https://www.nature.com/articles/s41598-021-93133-8

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
not-applicable
score
Not recorded
reason
Not a human randomized controlled trial.
evidence
evidence Type
Plant morphology measurements and mathematical model
evidence Class
biological_observation_and_model
measurement
Nine measured rose shoots; angular and height distributions
measured Genes
None recorded
pathways
None recorded
relationship Note
Background literature only. This paper does not test or validate an OXTR–Fibonacci relationship.
clinical Evidence
false
review Depth
Abstract and selected source passages: Results; Discussion; Methods.
full Paper Appraisal
Not completed; review depth states the material assessed.
Topics and recorded topic scores
  1. key
    general:fibonacci-biological-patterns
    title
    Biological patterns and developmental mechanisms
    collection
    general
    trust Score
    1
Citation snapshot and identifiers
id
nature-fibonacci-s41598-021-93133-8
doi
10.1038/s41598-021-93133-8
pmid
34226577
citation Snapshot
count
4
source
Crossref cited-by count
retrieved At
2026-10-24
url
https://api.crossref.org/works/10.1038/s41598-021-93133-8
field
is-referenced-by-count
source Indexed At
2026-02-26T20:00:06Z
coverage Note
Count reflects Crossref-deposited references and can differ from publisher or other database totals. It is not a quality or clinical-evidence score.
citations By Collection
general
4
Complete approved library record
id
nature-fibonacci-s41598-021-93133-8
aliases
None recorded
title
Discovery of spatial pattern of prickles on stem of Rosa hybrida ‘Red Queen’ and mathematical model of the pattern
journal
Scientific Reports
publisher Family
nature
publisher Family Label
Nature Portfolio
neurotransmitters
None recorded
year
2021
authors
Kazuaki Amikura; Hiroshi Ito; Miho S. Kitazawa
design
Plant morphology measurements and mathematical model
kind
Journal article
identity Conflict
Not recorded
doi
10.1038/s41598-021-93133-8
pmid
34226577
urls

https://www.nature.com/articles/s41598-021-93133-8 · https://doi.org/10.1038/s41598-021-93133-8 · https://pubmed.ncbi.nlm.nih.gov/34226577/

collections

general

categories

Fibonacci mathematics · Biological pattern formation

targets
None recorded
priority
1
quotes
None recorded
summary
Rose stems show a non-random distribution of prickles relative to spiral leaf phyllotaxis. A diffusion-based inhibition model reproduces the measured pattern and selected patterns in other plants.
limitation
The primary measurements cover nine shoots of one rose cultivar. The model assumes a patterning process; the responsible inhibitory factors and broader applicability remain unresolved.
citation Count
4
citation Snapshot
count
4
source
Crossref cited-by count
retrieved At
2026-10-24
url
https://api.crossref.org/works/10.1038/s41598-021-93133-8
field
is-referenced-by-count
source Indexed At
2026-02-26T20:00:06Z
coverage Note
Count reflects Crossref-deposited references and can differ from publisher or other database totals. It is not a quality or clinical-evidence score.
study Design Assessment
is Randomized Controlled Trial
false
blinding
Not applicable to a clinical-trial grade
basis
Plant morphology measurements and mathematical model. No human randomized controlled trial is reported.
sources

https://www.nature.com/articles/s41598-021-93133-8

category
peer-reviewed
peer Reviewed
true
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-confirmed
peer Reviewed
true
basis
Plant morphology measurements and mathematical model. No human randomized controlled trial is reported.
sources

https://pubmed.ncbi.nlm.nih.gov/34226577/ · https://www.nature.com/articles/s41598-021-93133-8

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
general
4
topics
  1. key
    general:fibonacci-biological-patterns
    title
    Biological patterns and developmental mechanisms
    collection
    general
    trust Score
    1
journal Key
scientificreports
journal Label
Scientific Reports
chapter Entries
  1. id
    general-nature-fibonacci-s41598-021-93133-8
    title
    Discovery of spatial pattern of prickles on stem of Rosa hybrida ‘Red Queen’ and mathematical model of the pattern
    journal
    Scientific Reports
    year
    2021
    authors
    Kazuaki Amikura; Hiroshi Ito; Miho S. Kitazawa
    doi
    10.1038/s41598-021-93133-8
    pmid
    34226577
    urls

    https://www.nature.com/articles/s41598-021-93133-8 · https://doi.org/10.1038/s41598-021-93133-8 · https://pubmed.ncbi.nlm.nih.gov/34226577/

    design
    Plant morphology measurements and mathematical model
    summary
    Rose stems show a non-random distribution of prickles relative to spiral leaf phyllotaxis. A diffusion-based inhibition model reproduces the measured pattern and selected patterns in other plants.
    limitation
    The primary measurements cover nine shoots of one rose cultivar. The model assumes a patterning process; the responsible inhibitory factors and broader applicability remain unresolved.
    citation Count
    4
    citation Snapshot
    count
    4
    source
    Crossref cited-by count
    retrieved At
    2026-10-24
    url
    https://api.crossref.org/works/10.1038/s41598-021-93133-8
    field
    is-referenced-by-count
    source Indexed At
    2026-02-26T20:00:06Z
    coverage Note
    Count reflects Crossref-deposited references and can differ from publisher or other database totals. It is not a quality or clinical-evidence score.
    categories

    Fibonacci mathematics · Biological pattern formation

    targets
    None recorded
    evidence
    evidence Type
    Plant morphology measurements and mathematical model
    evidence Class
    biological_observation_and_model
    measurement
    Nine measured rose shoots; angular and height distributions
    measured Genes
    None recorded
    pathways
    None recorded
    relationship Note
    Background literature only. This paper does not test or validate an OXTR–Fibonacci relationship.
    clinical Evidence
    false
    review Depth
    Abstract and selected source passages: Results; Discussion; Methods.
    full Paper Appraisal
    Not completed; review depth states the material assessed.
    record Id
    nature-fibonacci-s41598-021-93133-8
    quotes
    None recorded
    source Pages
    None recorded
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    false
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Plant morphology measurements and mathematical model. No human randomized controlled trial is reported.
    sources

    https://pubmed.ncbi.nlm.nih.gov/34226577/ · https://www.nature.com/articles/s41598-021-93133-8

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    study Design Assessment
    is Randomized Controlled Trial
    false
    blinding
    Not applicable to a clinical-trial grade
    basis
    Plant morphology measurements and mathematical model. No human randomized controlled trial is reported.
    sources

    https://www.nature.com/articles/s41598-021-93133-8

    category
    peer-reviewed
    peer Reviewed
    true
    collection
    general
    chapter Number
    9
    topic Id
    fibonacci-biological-patterns
    topic Title
    Biological patterns and developmental mechanisms
    trust Score
    1
evidence
evidence Type
Plant morphology measurements and mathematical model
evidence Class
biological_observation_and_model
measurement
Nine measured rose shoots; angular and height distributions
measured Genes
None recorded
pathways
None recorded
relationship Note
Background literature only. This paper does not test or validate an OXTR–Fibonacci relationship.
clinical Evidence
false
review Depth
Abstract and selected source passages: Results; Discussion; Methods.
full Paper Appraisal
Not completed; review depth states the material assessed.
jadad
status
not-applicable
score
Not recorded
reason
Not a human randomized controlled trial.
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

1

full Text
status
open-license
retrieval Available
true
url
https://www.nature.com/articles/s41598-021-93133-8
rights
license
http://creativecommons.org/licenses/by/4.0/
authors
Kazuaki, Amikura; Hiroshi, Ito; Miho S., Kitazawa
title
Discovery of spatial pattern of prickles on stem of Rosa hybrida ‘Red Queen’ and mathematical model of the pattern
doi
10.1038/s41598-021-93133-8
copyright
2021 The Author(s)
source
https://www.nature.com/articles/s41598-021-93133-8
transformation
Article sections extracted to plain text; navigation and recommendation sections removed. Equations, tables and image content may be incomplete; use the source for technical interpretation.
sha256
990112ca8da38d36c3ff8942f861d28e420cb2ff125a5a1b03a3547835b606cb
checked At
2026-10-24

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