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Repetitive transcranial magnetic stimulation is as effective as electroconvulsive therapy in the treatment of nondelusional major depressive disorder: an open study

Grunhaus L, Dannon PN, Schreiber S, Dolberg OH, Amiaz R, Ziv R, Lefkifker E. · Biological psychiatry · 2000 · Open randomized controlled trial

Original publication · Original publication

Attributed extracts from the research record

“The results we report are encouraging and support an important role for rTMS at 10hz in the treatment of severe major depressive disorder”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Open randomized controlled trial
assessment
category
rct-open-label
peer Reviewed
true
basis
The publication identifies the study as open and reports random assignment to rTMS or ECT.
sources

https://pubmed.ncbi.nlm.nih.gov/10686266/

assessed At
2026-10-27
review Scope
Primary abstract or specified methods and trial register; comprehensive full-text risk-of-bias assessment not completed.
trust Factor
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
open-label
peer Reviewed
true
basis
The publication identifies the study as open and reports random assignment to rTMS or ECT.
sources

https://pubmed.ncbi.nlm.nih.gov/10686266/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xiv
    title
    Transcranial magnetic stimulation: stimulation frequencies and depression
    collection
    sound
    trust Score
    3
Citation snapshot and identifiers
id
pmid-10686266
doi
10.1016/s0006-3223(99)00254-1
pmid
10686266
citation Snapshot
Not recorded
citations By Collection
sound
435
Complete approved library record
id
pmid-10686266
publication Key
Not recorded
aliases
None recorded
title
Repetitive transcranial magnetic stimulation is as effective as electroconvulsive therapy in the treatment of nondelusional major depressive disorder: an open study
journal
Biological psychiatry
neurotransmitters
None recorded
year
2000
authors
Grunhaus L, Dannon PN, Schreiber S, Dolberg OH, Amiaz R, Ziv R, Lefkifker E.
design
Open randomized controlled trial
kind
Journal article
identity Conflict
Not recorded
doi
10.1016/s0006-3223(99)00254-1
pmid
10686266
urls

https://doi.org/10.1016/s0006-3223(99)00254-1 · https://pubmed.ncbi.nlm.nih.gov/10686266/

collections

sound

categories

Methods & context

targets
None recorded
priority
1
quotes

“The results we report are encouraging and support an important role for rTMS at 10hz in the treatment of severe major depressive disorder”

summary
limitation
citation Count
435
study Design Assessment
category
rct-open-label
peer Reviewed
true
basis
The publication identifies the study as open and reports random assignment to rTMS or ECT.
sources

https://pubmed.ncbi.nlm.nih.gov/10686266/

assessed At
2026-10-27
review Scope
Primary abstract or specified methods and trial register; comprehensive full-text risk-of-bias assessment not completed.
paper Trust Assessment
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
open-label
peer Reviewed
true
basis
The publication identifies the study as open and reports random assignment to rTMS or ECT.
sources

https://pubmed.ncbi.nlm.nih.gov/10686266/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
435
topics
  1. key
    sound:xiv
    title
    Transcranial magnetic stimulation: stimulation frequencies and depression
    collection
    sound
    trust Score
    3
journal Key
biologicalpsychiatry
journal Label
Biological psychiatry
chapter Entries
  1. id
    xiv-pmid-10686266
    record Id
    pmid-10686266
    title
    Repetitive transcranial magnetic stimulation is as effective as electroconvulsive therapy in the treatment of nondelusional major depressive disorder: an open study
    journal
    Biological psychiatry
    year
    2000
    authors
    Grunhaus L, Dannon PN, Schreiber S, Dolberg OH, Amiaz R, Ziv R, Lefkifker E.
    design
    Open randomized controlled trial
    urls

    https://doi.org/10.1016/s0006-3223(99)00254-1 · https://pubmed.ncbi.nlm.nih.gov/10686266/

    quotes
      1. text
        “The results we report are encouraging and support an important role for rTMS at 10hz in the treatment of severe major depressive disorder”
        emphasis
        false
    citation Count
    435
    source Pages

    78

    targets
    None recorded
    categories

    Methods & context

    doi
    10.1016/s0006-3223(99)00254-1
    pmid
    10686266
    paper Trust Assessment
    score
    2
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    open-label
    peer Reviewed
    true
    basis
    The publication identifies the study as open and reports random assignment to rTMS or ECT.
    sources

    https://pubmed.ncbi.nlm.nih.gov/10686266/

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    study Design Assessment
    category
    rct-open-label
    peer Reviewed
    true
    basis
    The publication identifies the study as open and reports random assignment to rTMS or ECT.
    sources

    https://pubmed.ncbi.nlm.nih.gov/10686266/

    assessed At
    2026-10-27
    review Scope
    Primary abstract or specified methods and trial register; comprehensive full-text risk-of-bias assessment not completed.
    collection
    sound
    chapter Number
    4
    topic Id
    xiv
    topic Title
    Transcranial magnetic stimulation: stimulation frequencies and depression
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    depression
    evidence
    1. field
      title
      text
      Repetitive transcranial magnetic stimulation is as effective as electroconvulsive therapy in the treatment of nondelusional major depressive disorder: an open study
      matched Text
      depressive
conditions

depression

topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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