A randomized, wait-list controlled clinical trial: the effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients.
Speca M, Carlson LE, Goodey E, Angen M. · Psychosomatic medicine · 2000 · Randomized controlled trial
Original publication · Original publication
Recorded summary
Among 90 cancer outpatients completing a seven-week mindfulness programme, mood disturbance and stress symptoms improved relative to waitlist; the intervention group reported reductions of 65% and 31% respectively.
Recorded limitations
Those percentages describe change within the treated group, not the between-group treatment effect. The heterogeneous cancer population and waitlist comparison limit specificity.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Seven-week mindfulness stress reduction
- comparator
- Waitlist
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/11020090
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-11020090
- doi
- 10.1097/00006842-200009000-00004
- pmid
- 11020090
- citation Snapshot
- count
- 477
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/11020090
- citations By Collection
- language
- 477
Complete approved library record
- id
- pmid-11020090
- publication Key
- doi:10.1097/00006842-200009000-00004
- aliases
- None recorded
- title
- A randomized, wait-list controlled clinical trial: the effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients.
- journal
- Psychosomatic medicine
- neurotransmitters
- None recorded
- year
- 2000
- authors
- Speca M, Carlson LE, Goodey E, Angen M.
- design
- Randomized controlled trial
- identity Conflict
- Not recorded
- doi
- 10.1097/00006842-200009000-00004
- pmid
- 11020090
- urls
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- collections
language
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- Among 90 cancer outpatients completing a seven-week mindfulness programme, mood disturbance and stress symptoms improved relative to waitlist; the intervention group reported reductions of 65% and 31% respectively.
- limitation
- Those percentages describe change within the treated group, not the between-group treatment effect. The heterogeneous cancer population and waitlist comparison limit specificity.
- citation Count
- 477
- citation Snapshot
- count
- 477
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/11020090
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 477
- topics
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
- journal Key
- psychosomaticmedicine
- journal Label
- Psychosomatic medicine
- chapter Entries
- title
- A randomized, wait-list controlled clinical trial: the effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients.
- journal
- Psychosomatic medicine
- year
- 2000
- authors
- Speca M, Carlson LE, Goodey E, Angen M.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- doi
- 10.1097/00006842-200009000-00004
- pmid
- 11020090
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 477
- citation Snapshot
- count
- 477
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/11020090
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Seven-week mindfulness stress reduction
- comparator
- Waitlist
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/11020090
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- id
- language-mindfulness-clinical-pmid-11020090
- record Id
- pmid-11020090
- quotes
- None recorded
- source Pages
- None recorded
- summary
- Among 90 cancer outpatients completing a seven-week mindfulness programme, mood disturbance and stress symptoms improved relative to waitlist; the intervention group reported reductions of 65% and 31% respectively.
- limitation
- Those percentages describe change within the treated group, not the between-group treatment effect. The heterogeneous cancer population and waitlist comparison limit specificity.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1097/00006842-200009000-00004
- collection
- language
- chapter Number
- 4
- topic Id
- mindfulness-clinical
- topic Title
- Mindfulness-based interventions: controlled clinical trials
- trust Score
- 2
- evidence
- intervention
- Seven-week mindfulness stress reduction
- comparator
- Waitlist
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/11020090/ · https://doi.org/10.1097/00006842-200009000-00004
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/11020090
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- stress
- evidence
- field
- curated primary-source summary
- text
- Among 90 cancer outpatients completing a seven-week mindfulness programme, mood disturbance and stress symptoms improved relative to waitlist; the intervention group reported reductions of 65% and 31% respectively.
- matched Text
- stress
- conditions
stress
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false