Baroreflex and oscillation of heart period at 0.1 Hz studied by α ‐blockade and cross‐spectral analysis in healthy humans
Cevese A, Gulli G, Polati E, Gottin L, Grasso R. · The Journal of physiology · 2001
Original publication · Original publication
Attributed extracts from the research record
“Here we address the question as to whether the low frequency variability ( ∼ 0.1 Hz) of the heart period may depend on a baroreflex‐mediated response to blood pressure oscillations, induced by the α ‐sympathetic drive on the peripheral resistance.”
“We conclude that in supine rest conditions, the oscillation of RR at low frequency is almost entirely accounted for by a baroreflex mechanism, since it is not produced in the absence of a 0.1 Hz pressure oscillation.”
“The results provide physiological support for the use of non‐invasive estimates of the closed‐loop baroreflex gain from cross‐spectral analysis of blood pressure and heart period variability in the 0.1 Hz range.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/11179406/ · https://doi.org/10.1111/j.1469-7793.2001.0235j.x · https://physoc.onlinelibrary.wiley.com/doi/full/10.1111/j.1469-7793.2001.0235j.x
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- sound:ix
- title
- Baroreflex, heart-rate variability and Mayer waves around 0.1 Hz
- collection
- sound
- trust Score
- 1
Citation snapshot and identifiers
- id
- pmid-11179406
- doi
- 10.1111/j.1469-7793.2001.0235j.x
- pmid
- 11179406
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- 169
Complete approved library record
- id
- pmid-11179406
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Baroreflex and oscillation of heart period at 0.1 Hz studied by α ‐blockade and cross‐spectral analysis in healthy humans
- journal
- The Journal of physiology
- neurotransmitters
- None recorded
- year
- 2001
- authors
- Cevese A, Gulli G, Polati E, Gottin L, Grasso R.
- design
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1111/j.1469-7793.2001.0235j.x
- pmid
- 11179406
- urls
https://pubmed.ncbi.nlm.nih.gov/11179406/ · https://doi.org/10.1111/j.1469-7793.2001.0235j.x
- collections
sound
- categories
Heart rate & autonomic
- targets
- None recorded
- priority
- 1
- quotes
“Here we address the question as to whether the low frequency variability ( ∼ 0.1 Hz) of the heart period may depend on a baroreflex‐mediated response to blood pressure oscillations, induced by the α ‐sympathetic drive on the peripheral resistance.” · “We conclude that in supine rest conditions, the oscillation of RR at low frequency is almost entirely accounted for by a baroreflex mechanism, since it is not produced in the absence of a 0.1 Hz pressure oscillation.” · “The results provide physiological support for the use of non‐invasive estimates of the closed‐loop baroreflex gain from cross‐spectral analysis of blood pressure and heart period variability in the 0.1 Hz range.”
- summary
- limitation
- citation Count
- 169
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/11179406/ · https://doi.org/10.1111/j.1469-7793.2001.0235j.x · https://physoc.onlinelibrary.wiley.com/doi/full/10.1111/j.1469-7793.2001.0235j.x
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 169
- topics
- key
- sound:ix
- title
- Baroreflex, heart-rate variability and Mayer waves around 0.1 Hz
- collection
- sound
- trust Score
- 1
- journal Key
- journalofphysiology
- journal Label
- The Journal of physiology
- chapter Entries
- id
- ix-pmid-11179406
- record Id
- pmid-11179406
- title
- Baroreflex and oscillation of heart period at 0.1 Hz studied by α ‐blockade and cross‐spectral analysis in healthy humans
- journal
- The Journal of physiology
- year
- 2001
- authors
- Cevese A, Gulli G, Polati E, Gottin L, Grasso R.
- design
- urls
https://pubmed.ncbi.nlm.nih.gov/11179406/ · https://doi.org/10.1111/j.1469-7793.2001.0235j.x
- quotes
- text
- “Here we address the question as to whether the low frequency variability ( ∼ 0.1 Hz) of the heart period may depend on a baroreflex‐mediated response to blood pressure oscillations, induced by the α ‐sympathetic drive on the peripheral resistance.”
- emphasis
- false
- text
- “We conclude that in supine rest conditions, the oscillation of RR at low frequency is almost entirely accounted for by a baroreflex mechanism, since it is not produced in the absence of a 0.1 Hz pressure oscillation.”
- emphasis
- false
- text
- “The results provide physiological support for the use of non‐invasive estimates of the closed‐loop baroreflex gain from cross‐spectral analysis of blood pressure and heart period variability in the 0.1 Hz range.”
- emphasis
- false
- citation Count
- 169
- source Pages
64
- targets
- None recorded
- categories
Heart rate & autonomic
- doi
- 10.1111/j.1469-7793.2001.0235j.x
- pmid
- 11179406
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/11179406/ · https://doi.org/10.1111/j.1469-7793.2001.0235j.x · https://physoc.onlinelibrary.wiley.com/doi/full/10.1111/j.1469-7793.2001.0235j.x
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- sound
- chapter Number
- 2
- topic Id
- ix
- topic Title
- Baroreflex, heart-rate variability and Mayer waves around 0.1 Hz
- trust Score
- 1
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
1
- full Text
- status
- not-indexed
- retrieval Available
- false