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Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects.

Ma SH, Teasdale JD. · Journal of consulting and clinical psychology · 2004 · Randomized controlled trial

Original publication · Original publication

Recorded summary

In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.

Recorded limitations

The 18-person subgroup with two prior episodes showed the opposite numerical pattern. The successful result applies to the specified recurrent-depression subgroup and cannot be generalised across all depression histories.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial
assessment
category
peer-reviewed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

assessed At
2026-10-26
registered Masking Basis
false
trust Factor
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
not-confirmed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
intervention
Mindfulness-based cognitive therapy
comparator
Treatment as usual
evidence Type
Clinical or experimental outcomes
source URLs

https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

checked At
2026-10-26
review Scope
Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
discovery Sources

https://europepmc.org/article/MED/14756612

selection Policy
Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
  1. key
    language:mindfulness-clinical
    title
    Mindfulness-based interventions: controlled clinical trials
    collection
    language
    trust Score
    2
Citation snapshot and identifiers
id
pmid-14756612
doi
10.1037/0022-006x.72.1.31
pmid
14756612
citation Snapshot
count
547
source
Europe PMC
retrieved At
2026-10-26
url
https://europepmc.org/article/MED/14756612
citations By Collection
language
547
Complete approved library record
id
pmid-14756612
publication Key
doi:10.1037/0022-006x.72.1.31
aliases
None recorded
title
Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects.
journal
Journal of consulting and clinical psychology
neurotransmitters
None recorded
year
2004
authors
Ma SH, Teasdale JD.
design
Randomized controlled trial
identity Conflict
Not recorded
doi
10.1037/0022-006x.72.1.31
pmid
14756612
urls

https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

collections

language

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.
limitation
The 18-person subgroup with two prior episodes showed the opposite numerical pattern. The successful result applies to the specified recurrent-depression subgroup and cannot be generalised across all depression histories.
citation Count
547
citation Snapshot
count
547
source
Europe PMC
retrieved At
2026-10-26
url
https://europepmc.org/article/MED/14756612
study Design Assessment
category
peer-reviewed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

assessed At
2026-10-26
registered Masking Basis
false
paper Trust Assessment
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
not-confirmed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
language
547
topics
  1. key
    language:mindfulness-clinical
    title
    Mindfulness-based interventions: controlled clinical trials
    collection
    language
    trust Score
    2
journal Key
journalofconsultingandclinicalpsychology
journal Label
Journal of consulting and clinical psychology
chapter Entries
  1. title
    Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects.
    journal
    Journal of consulting and clinical psychology
    year
    2004
    authors
    Ma SH, Teasdale JD.
    design
    Randomized controlled trial
    urls

    https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

    doi
    10.1037/0022-006x.72.1.31
    pmid
    14756612
    targets
    None recorded
    categories

    Clinical & self-report

    citation Count
    547
    citation Snapshot
    count
    547
    source
    Europe PMC
    retrieved At
    2026-10-26
    url
    https://europepmc.org/article/MED/14756612
    study Design Assessment
    category
    peer-reviewed
    peer Reviewed
    true
    basis
    Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
    sources

    https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

    assessed At
    2026-10-26
    registered Masking Basis
    false
    evidence
    intervention
    Mindfulness-based cognitive therapy
    comparator
    Treatment as usual
    evidence Type
    Clinical or experimental outcomes
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

    checked At
    2026-10-26
    review Scope
    Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
    discovery Sources

    https://europepmc.org/article/MED/14756612

    selection Policy
    Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
    id
    language-mindfulness-clinical-pmid-14756612
    record Id
    pmid-14756612
    quotes
    None recorded
    source Pages
    None recorded
    summary
    In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.
    limitation
    The 18-person subgroup with two prior episodes showed the opposite numerical pattern. The successful result applies to the specified recurrent-depression subgroup and cannot be generalised across all depression histories.
    paper Trust Assessment
    score
    2
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
    sources

    https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    publication Key
    doi:10.1037/0022-006x.72.1.31
    collection
    language
    chapter Number
    4
    topic Id
    mindfulness-clinical
    topic Title
    Mindfulness-based interventions: controlled clinical trials
    trust Score
    2
evidence
intervention
Mindfulness-based cognitive therapy
comparator
Treatment as usual
evidence Type
Clinical or experimental outcomes
source URLs

https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31

checked At
2026-10-26
review Scope
Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
discovery Sources

https://europepmc.org/article/MED/14756612

selection Policy
Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    depression
    evidence
    1. field
      curated primary-source summary
      text
      In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.
      matched Text
      depression
conditions

depression

topic Trust Scores

2

full Text
status
not-indexed
retrieval Available
false

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