Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects.
Ma SH, Teasdale JD. · Journal of consulting and clinical psychology · 2004 · Randomized controlled trial
Original publication · Original publication
Recorded summary
In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.
Recorded limitations
The 18-person subgroup with two prior episodes showed the opposite numerical pattern. The successful result applies to the specified recurrent-depression subgroup and cannot be generalised across all depression histories.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Mindfulness-based cognitive therapy
- comparator
- Treatment as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/14756612
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-14756612
- doi
- 10.1037/0022-006x.72.1.31
- pmid
- 14756612
- citation Snapshot
- count
- 547
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/14756612
- citations By Collection
- language
- 547
Complete approved library record
- id
- pmid-14756612
- publication Key
- doi:10.1037/0022-006x.72.1.31
- aliases
- None recorded
- title
- Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects.
- journal
- Journal of consulting and clinical psychology
- neurotransmitters
- None recorded
- year
- 2004
- authors
- Ma SH, Teasdale JD.
- design
- Randomized controlled trial
- identity Conflict
- Not recorded
- doi
- 10.1037/0022-006x.72.1.31
- pmid
- 14756612
- urls
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- collections
language
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.
- limitation
- The 18-person subgroup with two prior episodes showed the opposite numerical pattern. The successful result applies to the specified recurrent-depression subgroup and cannot be generalised across all depression histories.
- citation Count
- 547
- citation Snapshot
- count
- 547
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/14756612
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 547
- topics
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
- journal Key
- journalofconsultingandclinicalpsychology
- journal Label
- Journal of consulting and clinical psychology
- chapter Entries
- title
- Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects.
- journal
- Journal of consulting and clinical psychology
- year
- 2004
- authors
- Ma SH, Teasdale JD.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- doi
- 10.1037/0022-006x.72.1.31
- pmid
- 14756612
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 547
- citation Snapshot
- count
- 547
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/14756612
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Mindfulness-based cognitive therapy
- comparator
- Treatment as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/14756612
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- id
- language-mindfulness-clinical-pmid-14756612
- record Id
- pmid-14756612
- quotes
- None recorded
- source Pages
- None recorded
- summary
- In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.
- limitation
- The 18-person subgroup with two prior episodes showed the opposite numerical pattern. The successful result applies to the specified recurrent-depression subgroup and cannot be generalised across all depression histories.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1037/0022-006x.72.1.31
- collection
- language
- chapter Number
- 4
- topic Id
- mindfulness-clinical
- topic Title
- Mindfulness-based interventions: controlled clinical trials
- trust Score
- 2
- evidence
- intervention
- Mindfulness-based cognitive therapy
- comparator
- Treatment as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/14756612/ · https://doi.org/10.1037/0022-006x.72.1.31
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/14756612
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- depression
- evidence
- field
- curated primary-source summary
- text
- In a 73-person recurrent-depression trial, MBCT reduced relapse among the 55 participants with three or more prior episodes: 36% relapsed versus 78% with usual care.
- matched Text
- depression
- conditions
depression
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false