Recreational music-making modulates the human stress response: a preliminary individualized gene expression strategy
Bittman B, Berk L, Shannon M, Sharaf M, Westengard J, Guegler KJ, Ruff DW. · Medical science monitor : international medical journal of experimental and clinical research · 2005
Attributed extracts from the research record
“The resultant amelioration of stress-induced genomic expression supports the underlying premise that recreational music making warrants additional consideration as a rational choice within our armamentarium of stress reduction strategies”
“While reversing individualized genomic stress induction signatures rather than describing the modulation or mecha- nisms associated with individual gene expression is the focus of this investigation, it should be noted that statistically significant Phase II reversals common to both the resting control and recreational music making experimental groups include: IL6 (interleukin 6)”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://pubmed.ncbi.nlm.nih.gov/15668624/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- sound:xii
- title
- Music-making, IL6 expression and the stress response
- collection
- sound
- trust Score
- Not recorded
Citation snapshot and identifiers
- id
- pmid-15668624
- doi
- Not recorded
- pmid
- 15668624
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- 99
Complete approved library record
- id
- pmid-15668624
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Recreational music-making modulates the human stress response: a preliminary individualized gene expression strategy
- journal
- Medical science monitor : international medical journal of experimental and clinical research
- neurotransmitters
- None recorded
- year
- 2005
- authors
- Bittman B, Berk L, Shannon M, Sharaf M, Westengard J, Guegler KJ, Ruff DW.
- design
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- Not recorded
- pmid
- 15668624
- urls
https://pubmed.ncbi.nlm.nih.gov/15668624/
- collections
sound
- categories
Gene expression · Genetics & genomics · Molecular biomarkers
- targets
IL6
- priority
- 0
- quotes
“The resultant amelioration of stress-induced genomic expression supports the underlying premise that recreational music making warrants additional consideration as a rational choice within our armamentarium of stress reduction strategies” · “While reversing individualized genomic stress induction signatures rather than describing the modulation or mecha- nisms associated with individual gene expression is the focus of this investigation, it should be noted that statistically significant Phase II reversals common to both the resting control and recreational music making experimental groups include: IL6 (interleukin 6)”
- summary
- limitation
- citation Count
- 99
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://pubmed.ncbi.nlm.nih.gov/15668624/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 99
- topics
- key
- sound:xii
- title
- Music-making, IL6 expression and the stress response
- collection
- sound
- trust Score
- Not recorded
- journal Key
- medicalsciencemonitor
- journal Label
- Medical science monitor : international medical journal of experimental and clinical research
- chapter Entries
- id
- xii-pmid-15668624
- record Id
- pmid-15668624
- title
- Recreational music-making modulates the human stress response: a preliminary individualized gene expression strategy
- journal
- Medical science monitor : international medical journal of experimental and clinical research
- year
- 2005
- authors
- Bittman B, Berk L, Shannon M, Sharaf M, Westengard J, Guegler KJ, Ruff DW.
- design
- urls
https://pubmed.ncbi.nlm.nih.gov/15668624/
- quotes
- text
- “The resultant amelioration of stress-induced genomic expression supports the underlying premise that recreational music making warrants additional consideration as a rational choice within our armamentarium of stress reduction strategies”
- emphasis
- false
- text
- “While reversing individualized genomic stress induction signatures rather than describing the modulation or mecha- nisms associated with individual gene expression is the focus of this investigation, it should be noted that statistically significant Phase II reversals common to both the resting control and recreational music making experimental groups include: IL6 (interleukin 6)”
- emphasis
- false
- citation Count
- 99
- source Pages
75
- targets
IL6
- categories
Gene expression · Genetics & genomics · Molecular biomarkers
- doi
- Not recorded
- pmid
- 15668624
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://pubmed.ncbi.nlm.nih.gov/15668624/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- sound
- chapter Number
- 3
- topic Id
- xii
- topic Title
- Music-making, IL6 expression and the stress response
- trust Score
- Not recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- stress
- evidence
- field
- title
- text
- Recreational music-making modulates the human stress response: a preliminary individualized gene expression strategy
- matched Text
- stress
- conditions
stress
- topic Trust Scores
- None recorded
- full Text
- status
- not-indexed
- retrieval Available
- false