A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance.
van der Kolk BA, Spinazzola J, Blaustein ME, Hopper JW, Hopper EK, Korn DL, Simpson WB. · The Journal of clinical psychiatry · 2007 · Randomized controlled trial
Original publication · Original publication
Attributed extracts from the research record
“This study supports the efficacy of brief EMDR treatment to produce substantial and sustained reduction of PTSD and depression in most victims of adult-onset trauma.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
- sources
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- reviewed At
- 2026-10-23
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
- sources
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- vision:i
- title
- EMDR for PTSD and related mental-health outcomes
- collection
- vision
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-17284128
- doi
- 10.4088/jcp.v68n0105
- pmid
- 17284128
- citation Snapshot
- count
- 315
- source
- Crossref
- retrieved At
- 2026-10-23
- citations By Collection
- vision
- 501
Complete approved library record
- id
- pmid-17284128
- publication Key
- doi:10.4088/jcp.v68n0105
- aliases
- None recorded
- title
- A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance.
- journal
- The Journal of clinical psychiatry
- neurotransmitters
- None recorded
- year
- 2007
- authors
- van der Kolk BA, Spinazzola J, Blaustein ME, Hopper JW, Hopper EK, Korn DL, Simpson WB.
- design
- Randomized controlled trial
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.4088/jcp.v68n0105
- pmid
- 17284128
- urls
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- collections
vision
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
“This study supports the efficacy of brief EMDR treatment to produce substantial and sustained reduction of PTSD and depression in most victims of adult-onset trauma.”
- summary
- limitation
- citation Count
- 501
- citation Snapshot
- count
- 315
- source
- Crossref
- retrieved At
- 2026-10-23
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
- sources
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- reviewed At
- 2026-10-23
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
- sources
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- 501
- topics
- key
- vision:i
- title
- EMDR for PTSD and related mental-health outcomes
- collection
- vision
- trust Score
- 2
- journal Key
- journalofclinicalpsychiatry
- journal Label
- The Journal of clinical psychiatry
- chapter Entries
- title
- A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance.
- journal
- The Journal of clinical psychiatry
- year
- 2007
- authors
- van der Kolk BA, Spinazzola J, Blaustein ME, Hopper JW, Hopper EK, Korn DL, Simpson WB.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- doi
- 10.4088/jcp.v68n0105
- pmid
- 17284128
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 501
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
- sources
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- reviewed At
- 2026-10-23
- record Id
- pmid-17284128
- quotes
- text
- “This study supports the efficacy of brief EMDR treatment to produce substantial and sustained reduction of PTSD and depression in most victims of adult-onset trauma.”
- emphasis
- false
- source Pages
3
- id
- vision-i-pmid-17284128
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
- sources
https://pubmed.ncbi.nlm.nih.gov/17284128/ · https://doi.org/10.4088/jcp.v68n0105
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.4088/jcp.v68n0105
- collection
- vision
- chapter Number
- 1
- topic Id
- i
- topic Title
- EMDR for PTSD and related mental-health outcomes
- trust Score
- 2
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- ptsd
- evidence
- field
- title
- text
- A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance.
- matched Text
- posttraumatic stress
- id
- trauma
- evidence
- field
- title
- text
- A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance.
- matched Text
- posttraumatic
- id
- stress
- evidence
- field
- title
- text
- A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance.
- matched Text
- stress
- conditions
ptsd · trauma · stress
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false