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Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial

O'Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, McDonald WM, Avery D, Fitzgerald PB, Loo C, Demitrack MA, George MS, Sackeim HA. · Biological psychiatry · 2007 · Double-blind randomized controlled trial

Original publication · Original publication

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Double-blind randomized controlled trial
assessment
category
double-blind-rct
peer Reviewed
true
basis
The primary abstract reports randomized active versus sham stimulation in a double-blind multisite trial.
sources

https://pubmed.ncbi.nlm.nih.gov/17573044/

assessed At
2026-10-27
review Scope
Primary abstract or specified methods and trial register; comprehensive full-text risk-of-bias assessment not completed.
trust Factor
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
true
basis
The primary abstract reports randomized active versus sham stimulation in a double-blind multisite trial.
sources

https://pubmed.ncbi.nlm.nih.gov/17573044/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
trial Id
NCT00104611
Topics and recorded topic scores
  1. key
    sound:xiv
    title
    Transcranial magnetic stimulation: stimulation frequencies and depression
    collection
    sound
    trust Score
    3
Citation snapshot and identifiers
id
pmid-17573044
doi
10.1016/j.biopsych.2007.01.018
pmid
17573044
citation Snapshot
Not recorded
citations By Collection
sound
1304
Complete approved library record
id
pmid-17573044
publication Key
Not recorded
aliases
None recorded
title
Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial
journal
Biological psychiatry
neurotransmitters
None recorded
year
2007
authors
O'Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, McDonald WM, Avery D, Fitzgerald PB, Loo C, Demitrack MA, George MS, Sackeim HA.
design
Double-blind randomized controlled trial
kind
Journal article
identity Conflict
Not recorded
doi
10.1016/j.biopsych.2007.01.018
pmid
17573044
urls

https://doi.org/10.1016/j.biopsych.2007.01.018 · https://pubmed.ncbi.nlm.nih.gov/17573044/

collections

sound

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
limitation
citation Count
1304
study Design Assessment
category
double-blind-rct
peer Reviewed
true
basis
The primary abstract reports randomized active versus sham stimulation in a double-blind multisite trial.
sources

https://pubmed.ncbi.nlm.nih.gov/17573044/

assessed At
2026-10-27
review Scope
Primary abstract or specified methods and trial register; comprehensive full-text risk-of-bias assessment not completed.
paper Trust Assessment
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
true
basis
The primary abstract reports randomized active versus sham stimulation in a double-blind multisite trial.
sources

https://pubmed.ncbi.nlm.nih.gov/17573044/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
1304
topics
  1. key
    sound:xiv
    title
    Transcranial magnetic stimulation: stimulation frequencies and depression
    collection
    sound
    trust Score
    3
journal Key
biologicalpsychiatry
journal Label
Biological psychiatry
chapter Entries
  1. id
    xiv-pmid-17573044
    record Id
    pmid-17573044
    title
    Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial
    journal
    Biological psychiatry
    year
    2007
    authors
    O'Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, McDonald WM, Avery D, Fitzgerald PB, Loo C, Demitrack MA, George MS, Sackeim HA.
    design
    Double-blind randomized controlled trial
    urls

    https://doi.org/10.1016/j.biopsych.2007.01.018 · https://pubmed.ncbi.nlm.nih.gov/17573044/

    quotes
    None recorded
    citation Count
    1304
    source Pages

    77

    targets
    None recorded
    categories

    Clinical & self-report

    doi
    10.1016/j.biopsych.2007.01.018
    pmid
    17573044
    paper Trust Assessment
    score
    3
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    double
    peer Reviewed
    true
    basis
    The primary abstract reports randomized active versus sham stimulation in a double-blind multisite trial.
    sources

    https://pubmed.ncbi.nlm.nih.gov/17573044/

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    study Design Assessment
    category
    double-blind-rct
    peer Reviewed
    true
    basis
    The primary abstract reports randomized active versus sham stimulation in a double-blind multisite trial.
    sources

    https://pubmed.ncbi.nlm.nih.gov/17573044/

    assessed At
    2026-10-27
    review Scope
    Primary abstract or specified methods and trial register; comprehensive full-text risk-of-bias assessment not completed.
    evidence
    trial Id
    NCT00104611
    collection
    sound
    chapter Number
    4
    topic Id
    xiv
    topic Title
    Transcranial magnetic stimulation: stimulation frequencies and depression
    trust Score
    3
evidence
trial Id
NCT00104611
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    depression
    evidence
    1. field
      title
      text
      Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial
      matched Text
      Depression
conditions

depression

topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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