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Dopamine and Oxytocin Interactions Underlying Behaviors: Potential Contributions to Behavioral Disorders

Baskerville TA, Douglas AJ. · CNS neuroscience & therapeutics · 2010

Original publication · Original publication · Original publication

Attributed extracts from the research record

“In addition to psychosocial improvement, oxytocin has recently been implicated in mediating mesolimbic dopamine pathways during drug addiction and withdrawal. Central oxytocin pathways may serve as a potential therapeutic target to improve mood and socio‐affiliative behaviors in patients with profound social deficits and/or drug addiction.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-applicable
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/20557568/ · https://doi.org/10.1111/j.1755-5949.2010.00154.x · https://onlinelibrary.wiley.com/doi/full/10.1111/j.1755-5949.2010.00154.x

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    general
    trust Score
    1
Citation snapshot and identifiers
id
pmid-20557568
doi
10.1111/j.1755-5949.2010.00154.x
pmid
20557568
citation Snapshot
Not recorded
citations By Collection
sound
315
general
315
Complete approved library record
id
pmid-20557568
publication Key
Not recorded
aliases
None recorded
title
Dopamine and Oxytocin Interactions Underlying Behaviors: Potential Contributions to Behavioral Disorders
journal
CNS neuroscience & therapeutics
neurotransmitters
None recorded
year
2010
authors
Baskerville TA, Douglas AJ.
design
kind
Review / synthesis
identity Conflict
Not recorded
doi
10.1111/j.1755-5949.2010.00154.x
pmid
20557568
urls

https://pmc.ncbi.nlm.nih.gov/articles/PMC6493805/ · https://pubmed.ncbi.nlm.nih.gov/20557568/ · https://doi.org/10.1111/j.1755-5949.2010.00154.x

collections

sound · general

categories

Molecular biomarkers

targets

OXT

priority
1
quotes

“In addition to psychosocial improvement, oxytocin has recently been implicated in mediating mesolimbic dopamine pathways during drug addiction and withdrawal. Central oxytocin pathways may serve as a potential therapeutic target to improve mood and socio‐affiliative behaviors in patients with profound social deficits and/or drug addiction.”

summary
limitation
citation Count
315
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-applicable
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/20557568/ · https://doi.org/10.1111/j.1755-5949.2010.00154.x · https://onlinelibrary.wiley.com/doi/full/10.1111/j.1755-5949.2010.00154.x

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
315
general
315
topics
  1. key
    sound:xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    general
    trust Score
    1
journal Key
cnsneuroscienceandtherapeutics
journal Label
CNS neuroscience & therapeutics
chapter Entries
  1. id
    xxix-pmid-20557568
    record Id
    pmid-20557568
    title
    Dopamine and Oxytocin Interactions Underlying Behaviors: Potential Contributions to Behavioral Disorders
    journal
    CNS neuroscience & therapeutics
    year
    2010
    authors
    Baskerville TA, Douglas AJ.
    design
    urls

    https://pmc.ncbi.nlm.nih.gov/articles/PMC6493805/ · https://pubmed.ncbi.nlm.nih.gov/20557568/ · https://doi.org/10.1111/j.1755-5949.2010.00154.x

    quotes
      1. text
        “In addition to psychosocial improvement, oxytocin has recently been implicated in mediating mesolimbic dopamine pathways during drug addiction and withdrawal. Central oxytocin pathways may serve as a potential therapeutic target to improve mood and socio‐affiliative behaviors in patients with profound social deficits and/or drug addiction.”
        emphasis
        false
    citation Count
    315
    source Pages

    118

    targets

    OXT

    categories

    Molecular biomarkers

    doi
    10.1111/j.1755-5949.2010.00154.x
    pmid
    20557568
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    false
    blinding
    not-applicable
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/20557568/ · https://doi.org/10.1111/j.1755-5949.2010.00154.x · https://onlinelibrary.wiley.com/doi/full/10.1111/j.1755-5949.2010.00154.x

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    6
    topic Id
    xxix
    topic Title
    Oxytocin pathways, dopamine and serotonin
    trust Score
    1
  2. id
    general-xxix-pmid-20557568
    record Id
    pmid-20557568
    title
    Dopamine and Oxytocin Interactions Underlying Behaviors: Potential Contributions to Behavioral Disorders
    journal
    CNS neuroscience & therapeutics
    year
    2010
    authors
    Baskerville TA, Douglas AJ.
    design
    urls

    https://pmc.ncbi.nlm.nih.gov/articles/PMC6493805/ · https://pubmed.ncbi.nlm.nih.gov/20557568/ · https://doi.org/10.1111/j.1755-5949.2010.00154.x

    quotes
      1. text
        “In addition to psychosocial improvement, oxytocin has recently been implicated in mediating mesolimbic dopamine pathways during drug addiction and withdrawal. Central oxytocin pathways may serve as a potential therapeutic target to improve mood and socio‐affiliative behaviors in patients with profound social deficits and/or drug addiction.”
        emphasis
        false
    citation Count
    315
    source Pages

    118

    targets

    OXT

    categories

    Molecular biomarkers

    doi
    10.1111/j.1755-5949.2010.00154.x
    pmid
    20557568
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    false
    blinding
    not-applicable
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/20557568/ · https://doi.org/10.1111/j.1755-5949.2010.00154.x · https://onlinelibrary.wiley.com/doi/full/10.1111/j.1755-5949.2010.00154.x

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    1
    topic Id
    sound-xxix
    topic Title
    Oxytocin pathways, dopamine and serotonin
    trust Score
    1
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

1

full Text
status
not-indexed
retrieval Available
false

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