Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
Ghanizadeh A, Berk M. · Medical gas research · 2013
Original publication · Original publication · Original publication
Attributed extracts from the research record
“it is hypothesized that administration of hydrogen molecule may have potential as a novel therapy for bipolar disorder, schizophrenia, and other concurrent disorders characterized by oxidative, inflammatory and apoptotic dysregulation.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/23742229/ · https://doi.org/10.1186/2045-9912-3-11 · https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-11
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- language:vi
- title
- Molecular hydrogen: inflammation, cognition and gene expression
- collection
- language
- trust Score
- 3
- key
- general:language-vi
- title
- Molecular hydrogen: inflammation, cognition and gene expression
- collection
- general
- trust Score
- 3
Citation snapshot and identifiers
- id
- pmid-23742229
- doi
- 10.1186/2045-9912-3-11
- pmid
- 23742229
- citation Snapshot
- Not recorded
- citations By Collection
- language
- 21
- general
- 21
Complete approved library record
- id
- pmid-23742229
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
- journal
- Medical gas research
- neurotransmitters
- None recorded
- year
- 2013
- authors
- Ghanizadeh A, Berk M.
- design
- kind
- Review / synthesis
- identity Conflict
- Not recorded
- doi
- 10.1186/2045-9912-3-11
- pmid
- 23742229
- urls
https://doi.org/10.1186/2045-9912-3-11 · https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-11 · https://pubmed.ncbi.nlm.nih.gov/23742229/
- collections
language · general
- categories
Molecular biomarkers · Methods & context
- targets
- None recorded
- priority
- 1
- quotes
“it is hypothesized that administration of hydrogen molecule may have potential as a novel therapy for bipolar disorder, schizophrenia, and other concurrent disorders characterized by oxidative, inflammatory and apoptotic dysregulation.”
- summary
- limitation
- citation Count
- 21
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/23742229/ · https://doi.org/10.1186/2045-9912-3-11 · https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-11
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 21
- general
- 21
- topics
- key
- language:vi
- title
- Molecular hydrogen: inflammation, cognition and gene expression
- collection
- language
- trust Score
- 3
- key
- general:language-vi
- title
- Molecular hydrogen: inflammation, cognition and gene expression
- collection
- general
- trust Score
- 3
- journal Key
- medicalgasresearch
- journal Label
- Medical gas research
- chapter Entries
- id
- language-vi-pmid-23742229
- record Id
- pmid-23742229
- title
- Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
- journal
- Medical gas research
- year
- 2013
- authors
- Ghanizadeh A, Berk M.
- design
- urls
https://doi.org/10.1186/2045-9912-3-11 · https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-11 · https://pubmed.ncbi.nlm.nih.gov/23742229/
- quotes
- text
- “it is hypothesized that administration of hydrogen molecule may have potential as a novel therapy for bipolar disorder, schizophrenia, and other concurrent disorders characterized by oxidative, inflammatory and apoptotic dysregulation.”
- emphasis
- false
- citation Count
- 21
- source Pages
26
- targets
- None recorded
- categories
Molecular biomarkers · Methods & context
- doi
- 10.1186/2045-9912-3-11
- pmid
- 23742229
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/23742229/ · https://doi.org/10.1186/2045-9912-3-11 · https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-11
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- language
- chapter Number
- 1
- topic Id
- vi
- topic Title
- Molecular hydrogen: inflammation, cognition and gene expression
- trust Score
- 3
- id
- general-language-vi-pmid-23742229
- record Id
- pmid-23742229
- title
- Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
- journal
- Medical gas research
- year
- 2013
- authors
- Ghanizadeh A, Berk M.
- design
- urls
https://doi.org/10.1186/2045-9912-3-11 · https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-11 · https://pubmed.ncbi.nlm.nih.gov/23742229/
- quotes
- text
- “it is hypothesized that administration of hydrogen molecule may have potential as a novel therapy for bipolar disorder, schizophrenia, and other concurrent disorders characterized by oxidative, inflammatory and apoptotic dysregulation.”
- emphasis
- false
- citation Count
- 21
- source Pages
26
- targets
- None recorded
- categories
Molecular biomarkers · Methods & context
- doi
- 10.1186/2045-9912-3-11
- pmid
- 23742229
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/23742229/ · https://doi.org/10.1186/2045-9912-3-11 · https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-11
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- general
- chapter Number
- 3
- topic Id
- language-vi
- topic Title
- Molecular hydrogen: inflammation, cognition and gene expression
- trust Score
- 3
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- schizophrenia
- evidence
- field
- title
- text
- Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
- matched Text
- schizophrenia
- id
- bipolar
- evidence
- field
- title
- text
- Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
- matched Text
- bipolar
- conditions
schizophrenia · bipolar
- topic Trust Scores
3
- full Text
- status
- open-license
- retrieval Available
- true
- url
- https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3680337/fullTextXML
- pmcid
- PMC3680337
- rights
- license
- http://creativecommons.org/licenses/by/2.0
- statement
Copyright © 2013 Ghanizadeh and Berk; licensee BioMed Central Ltd. 2013 Ghanizadeh and Berk; licensee BioMed Central Ltd. https://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- sha256
- 84bff9276adb4e4ca077b20013e1908774f9f4a41492536b706ffc4bba0b550b
- checked At
- 2026-10-24