Relative efficacy of mindfulness-based relapse prevention, standard relapse prevention, and treatment as usual for substance use disorders: a randomized clinical trial.
Bowen S, Witkiewitz K, Clifasefi SL, Grow J, Chawla N, Hsu SH, Carroll HA, Harrop E, Collins SE, Lustyk MK, Larimer ME. · JAMA psychiatry · 2014 · Randomized controlled trial
Original publication · Original publication · Original publication
Recorded summary
In 286 adults completing substance-use treatment, mindfulness-based relapse prevention reduced substance-use days and heavy drinking at 12 months relative to standard relapse prevention and usual aftercare.
Recorded limitations
Benefits varied by endpoint and time: standard relapse prevention delayed first drug use more effectively at six months. Results concern structured aftercare, not a stand-alone meditation cure for addiction.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Mindfulness-based relapse prevention
- comparator
- Relapse prevention and usual aftercare
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/24647726
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT01159535
Topics and recorded topic scores
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-24647726
- doi
- 10.1001/jamapsychiatry.2013.4546
- pmid
- 24647726
- citation Snapshot
- count
- 384
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/24647726
- citations By Collection
- language
- 384
Complete approved library record
- id
- pmid-24647726
- publication Key
- doi:10.1001/jamapsychiatry.2013.4546
- aliases
- None recorded
- title
- Relative efficacy of mindfulness-based relapse prevention, standard relapse prevention, and treatment as usual for substance use disorders: a randomized clinical trial.
- journal
- JAMA psychiatry
- neurotransmitters
- None recorded
- year
- 2014
- authors
- Bowen S, Witkiewitz K, Clifasefi SL, Grow J, Chawla N, Hsu SH, Carroll HA, Harrop E, Collins SE, Lustyk MK, Larimer ME.
- design
- Randomized controlled trial
- identity Conflict
- Not recorded
- doi
- 10.1001/jamapsychiatry.2013.4546
- pmid
- 24647726
- urls
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- collections
language
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- In 286 adults completing substance-use treatment, mindfulness-based relapse prevention reduced substance-use days and heavy drinking at 12 months relative to standard relapse prevention and usual aftercare.
- limitation
- Benefits varied by endpoint and time: standard relapse prevention delayed first drug use more effectively at six months. Results concern structured aftercare, not a stand-alone meditation cure for addiction.
- citation Count
- 384
- citation Snapshot
- count
- 384
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/24647726
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 384
- topics
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
- journal Key
- jamapsychiatry
- journal Label
- JAMA psychiatry
- chapter Entries
- title
- Relative efficacy of mindfulness-based relapse prevention, standard relapse prevention, and treatment as usual for substance use disorders: a randomized clinical trial.
- journal
- JAMA psychiatry
- year
- 2014
- authors
- Bowen S, Witkiewitz K, Clifasefi SL, Grow J, Chawla N, Hsu SH, Carroll HA, Harrop E, Collins SE, Lustyk MK, Larimer ME.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- doi
- 10.1001/jamapsychiatry.2013.4546
- pmid
- 24647726
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 384
- citation Snapshot
- count
- 384
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/24647726
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Mindfulness-based relapse prevention
- comparator
- Relapse prevention and usual aftercare
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/24647726
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT01159535
- id
- language-mindfulness-clinical-pmid-24647726
- record Id
- pmid-24647726
- quotes
- None recorded
- source Pages
- None recorded
- summary
- In 286 adults completing substance-use treatment, mindfulness-based relapse prevention reduced substance-use days and heavy drinking at 12 months relative to standard relapse prevention and usual aftercare.
- limitation
- Benefits varied by endpoint and time: standard relapse prevention delayed first drug use more effectively at six months. Results concern structured aftercare, not a stand-alone meditation cure for addiction.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1001/jamapsychiatry.2013.4546
- collection
- language
- chapter Number
- 4
- topic Id
- mindfulness-clinical
- topic Title
- Mindfulness-based interventions: controlled clinical trials
- trust Score
- 2
- evidence
- intervention
- Mindfulness-based relapse prevention
- comparator
- Relapse prevention and usual aftercare
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/24647726/ · https://doi.org/10.1001/jamapsychiatry.2013.4546 · https://pmc.ncbi.nlm.nih.gov/articles/PMC4489711/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/24647726
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT01159535
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- substance-use
- evidence
- field
- curated primary-source summary
- text
- In 286 adults completing substance-use treatment, mindfulness-based relapse prevention reduced substance-use days and heavy drinking at 12 months relative to standard relapse prevention and usual aftercare.
- matched Text
- substance-use
- conditions
substance-use
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false