Oxytocin expression and function in the posterior retina: a novel signaling pathway
Halbach P, Pillers DA, York N, Asuma MP, Chiu MA, Luo W, Tokarz S, Bird IM, Pattnaik BR. · Investigative ophthalmology & visual science · 2015 · Human and rhesus tissue; cultured human retinal cells
Original publication · Original publication · Original publication
Recorded summary
The study identified OXT/OXTR signalling components in posterior retinal tissues and a calcium response to oxytocin in cultured retinal pigment epithelial cells.
Recorded limitations
This is a foundational 2015 study, added for context. Receptor presence and activation do not demonstrate visual-exposure-induced gene expression.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Human and rhesus tissue; cultured human retinal cells
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/25593022/ · https://doi.org/10.1167/iovs.14-15646
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-25593022
- doi
- 10.1167/iovs.14-15646
- pmid
- 25593022
- citation Snapshot
- Not recorded
- citations By Collection
- vision
- Not recorded
Complete approved library record
- id
- pmid-25593022
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Oxytocin expression and function in the posterior retina: a novel signaling pathway
- journal
- Investigative ophthalmology & visual science
- neurotransmitters
- None recorded
- year
- 2015
- authors
- Halbach P, Pillers DA, York N, Asuma MP, Chiu MA, Luo W, Tokarz S, Bird IM, Pattnaik BR.
- design
- Human and rhesus tissue; cultured human retinal cells
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1167/iovs.14-15646
- pmid
- 25593022
- urls
https://pmc.ncbi.nlm.nih.gov/articles/PMC4554231/ · https://pubmed.ncbi.nlm.nih.gov/25593022/ · https://doi.org/10.1167/iovs.14-15646
- collections
vision
- categories
Gene expression · Molecular biomarkers
- targets
OXTR · OXT
- priority
- 0
- quotes
- None recorded
- summary
- The study identified OXT/OXTR signalling components in posterior retinal tissues and a calcium response to oxytocin in cultured retinal pigment epithelial cells.
- limitation
- This is a foundational 2015 study, added for context. Receptor presence and activation do not demonstrate visual-exposure-induced gene expression.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/25593022/ · https://doi.org/10.1167/iovs.14-15646
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- Not recorded
- topics
- None recorded
- journal Key
- investigativeophthalmologyandvisualscience
- journal Label
- Investigative ophthalmology & visual science
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- not-indexed
- retrieval Available
- false