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The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576)

Weisman O, Pelphrey KA, Leckman JF, Feldman R, Lu Y, Chong A, Chen Y, Monakhov M, Chew SH, Ebstein RP. · Psychoneuroendocrinology · 2015

Original publication · Original publication

Attributed extracts from the research record

“The current findings show that OXTR rs53576 interacts with 2D:4D to shape one's cognitive empathy aptitude.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/25935637/ · https://doi.org/10.1016/j.psyneuen.2015.04.007 · https://www.sciencedirect.com/science/article/abs/pii/S030645301500147X

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xxx
    title
    OXTR variation and psychological resources
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxx
    title
    OXTR variation and psychological resources
    collection
    general
    trust Score
    1
Citation snapshot and identifiers
id
pmid-25935637
doi
10.1016/j.psyneuen.2015.04.007
pmid
25935637
citation Snapshot
Not recorded
citations By Collection
sound
67
general
67
Complete approved library record
id
pmid-25935637
publication Key
Not recorded
aliases
None recorded
title
The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576)
journal
Psychoneuroendocrinology
neurotransmitters
None recorded
year
2015
authors
Weisman O, Pelphrey KA, Leckman JF, Feldman R, Lu Y, Chong A, Chen Y, Monakhov M, Chew SH, Ebstein RP.
design
kind
Journal article
identity Conflict
Not recorded
doi
10.1016/j.psyneuen.2015.04.007
pmid
25935637
urls

https://doi.org/10.1016/j.psyneuen.2015.04.007 · https://pubmed.ncbi.nlm.nih.gov/25935637/

collections

sound · general

categories

Genetics & genomics · Molecular biomarkers · Brain & nervous system

targets

OXTR · OXT

priority
0
quotes

“The current findings show that OXTR rs53576 interacts with 2D:4D to shape one's cognitive empathy aptitude.”

summary
limitation
citation Count
67
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/25935637/ · https://doi.org/10.1016/j.psyneuen.2015.04.007 · https://www.sciencedirect.com/science/article/abs/pii/S030645301500147X

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
67
general
67
topics
  1. key
    sound:xxx
    title
    OXTR variation and psychological resources
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxx
    title
    OXTR variation and psychological resources
    collection
    general
    trust Score
    1
journal Key
psychoneuroendocrinology
journal Label
Psychoneuroendocrinology
chapter Entries
  1. id
    xxx-pmid-25935637
    record Id
    pmid-25935637
    title
    The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576)
    journal
    Psychoneuroendocrinology
    year
    2015
    authors
    Weisman O, Pelphrey KA, Leckman JF, Feldman R, Lu Y, Chong A, Chen Y, Monakhov M, Chew SH, Ebstein RP.
    design
    urls

    https://doi.org/10.1016/j.psyneuen.2015.04.007 · https://pubmed.ncbi.nlm.nih.gov/25935637/

    quotes
      1. text
        “The current findings show that OXTR rs53576 interacts with 2D:4D to shape one's cognitive empathy aptitude.”
        emphasis
        false
    citation Count
    67
    source Pages

    121

    targets

    OXTR · OXT

    categories

    Genetics & genomics · Molecular biomarkers · Brain & nervous system

    doi
    10.1016/j.psyneuen.2015.04.007
    pmid
    25935637
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/25935637/ · https://doi.org/10.1016/j.psyneuen.2015.04.007 · https://www.sciencedirect.com/science/article/abs/pii/S030645301500147X

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    6
    topic Id
    xxx
    topic Title
    OXTR variation and psychological resources
    trust Score
    1
  2. id
    general-xxx-pmid-25935637
    record Id
    pmid-25935637
    title
    The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576)
    journal
    Psychoneuroendocrinology
    year
    2015
    authors
    Weisman O, Pelphrey KA, Leckman JF, Feldman R, Lu Y, Chong A, Chen Y, Monakhov M, Chew SH, Ebstein RP.
    design
    urls

    https://doi.org/10.1016/j.psyneuen.2015.04.007 · https://pubmed.ncbi.nlm.nih.gov/25935637/

    quotes
      1. text
        “The current findings show that OXTR rs53576 interacts with 2D:4D to shape one's cognitive empathy aptitude.”
        emphasis
        false
    citation Count
    67
    source Pages

    121

    targets

    OXTR · OXT

    categories

    Genetics & genomics · Molecular biomarkers · Brain & nervous system

    doi
    10.1016/j.psyneuen.2015.04.007
    pmid
    25935637
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/25935637/ · https://doi.org/10.1016/j.psyneuen.2015.04.007 · https://www.sciencedirect.com/science/article/abs/pii/S030645301500147X

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    1
    topic Id
    sound-xxx
    topic Title
    OXTR variation and psychological resources
    trust Score
    1
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

1

full Text
status
not-indexed
retrieval Available
false

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