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Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial

Song G, Lin Q, Zhao H, Liu M, Ye F, Sun Y, Yu Y, Guo S, Jiao P, Wu Y, Ding G, Xiao Q, Qin S. · The Journal of clinical endocrinology and metabolism · 2015 · randomised controlled trial, double blind

Original publication · Original publication

Attributed extracts from the research record

“The present findings highlight the potential role of H2 in the regression of hypercholesterolemia and atherosclerosis.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
randomised controlled trial, double blind
assessment
Not recorded
trust Factor
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
true
basis
Indexed randomized trial and double-blind methods.
sources

https://pubmed.ncbi.nlm.nih.gov/25978109/ · https://doi.org/10.1210/jc.2015-1321

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    language:vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    language
    trust Score
    3
  2. key
    general:language-vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    general
    trust Score
    3
Citation snapshot and identifiers
id
pmid-25978109
doi
10.1210/jc.2015-1321
pmid
25978109
citation Snapshot
Not recorded
citations By Collection
language
30
general
30
Complete approved library record
id
pmid-25978109
publication Key
Not recorded
aliases
None recorded
title
Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial
journal
The Journal of clinical endocrinology and metabolism
neurotransmitters
None recorded
year
2015
authors
Song G, Lin Q, Zhao H, Liu M, Ye F, Sun Y, Yu Y, Guo S, Jiao P, Wu Y, Ding G, Xiao Q, Qin S.
design
randomised controlled trial, double blind
kind
Journal article
identity Conflict
Not recorded
doi
10.1210/jc.2015-1321
pmid
25978109
urls

https://pubmed.ncbi.nlm.nih.gov/25978109/ · https://doi.org/10.1210/jc.2015-1321

collections

language · general

categories

Methods & context

targets
None recorded
priority
1
quotes

“The present findings highlight the potential role of H2 in the regression of hypercholesterolemia and atherosclerosis.”

summary
limitation
citation Count
30
paper Trust Assessment
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
true
basis
Indexed randomized trial and double-blind methods.
sources

https://pubmed.ncbi.nlm.nih.gov/25978109/ · https://doi.org/10.1210/jc.2015-1321

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
language
30
general
30
topics
  1. key
    language:vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    language
    trust Score
    3
  2. key
    general:language-vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    general
    trust Score
    3
journal Key
journalofclinicalendocrinologyandmetabolism
journal Label
The Journal of clinical endocrinology and metabolism
chapter Entries
  1. id
    language-vi-pmid-25978109
    record Id
    pmid-25978109
    title
    Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial
    journal
    The Journal of clinical endocrinology and metabolism
    year
    2015
    authors
    Song G, Lin Q, Zhao H, Liu M, Ye F, Sun Y, Yu Y, Guo S, Jiao P, Wu Y, Ding G, Xiao Q, Qin S.
    design
    randomised controlled trial, double blind
    urls

    https://pubmed.ncbi.nlm.nih.gov/25978109/ · https://doi.org/10.1210/jc.2015-1321

    quotes
      1. text
        “The present findings highlight the potential role of H2 in the regression of hypercholesterolemia and atherosclerosis.”
        emphasis
        false
    citation Count
    30
    source Pages

    25

    targets
    None recorded
    categories

    Methods & context

    doi
    10.1210/jc.2015-1321
    pmid
    25978109
    paper Trust Assessment
    score
    3
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    double
    peer Reviewed
    true
    basis
    Indexed randomized trial and double-blind methods.
    sources

    https://pubmed.ncbi.nlm.nih.gov/25978109/ · https://doi.org/10.1210/jc.2015-1321

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    language
    chapter Number
    1
    topic Id
    vi
    topic Title
    Molecular hydrogen: inflammation, cognition and gene expression
    trust Score
    3
  2. id
    general-language-vi-pmid-25978109
    record Id
    pmid-25978109
    title
    Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial
    journal
    The Journal of clinical endocrinology and metabolism
    year
    2015
    authors
    Song G, Lin Q, Zhao H, Liu M, Ye F, Sun Y, Yu Y, Guo S, Jiao P, Wu Y, Ding G, Xiao Q, Qin S.
    design
    randomised controlled trial, double blind
    urls

    https://pubmed.ncbi.nlm.nih.gov/25978109/ · https://doi.org/10.1210/jc.2015-1321

    quotes
      1. text
        “The present findings highlight the potential role of H2 in the regression of hypercholesterolemia and atherosclerosis.”
        emphasis
        false
    citation Count
    30
    source Pages

    25

    targets
    None recorded
    categories

    Methods & context

    doi
    10.1210/jc.2015-1321
    pmid
    25978109
    paper Trust Assessment
    score
    3
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    double
    peer Reviewed
    true
    basis
    Indexed randomized trial and double-blind methods.
    sources

    https://pubmed.ncbi.nlm.nih.gov/25978109/ · https://doi.org/10.1210/jc.2015-1321

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    3
    topic Id
    language-vi
    topic Title
    Molecular hydrogen: inflammation, cognition and gene expression
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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