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Mindfulness meditation and the immune system: a systematic review of randomized controlled trials

Black DS, Slavich GM. · Annals of the New York Academy of Sciences · 2016 · randomised controlled trial

Original publication · Original publication · Original publication

Attributed extracts from the research record

“The findings suggest possible effects of mindfulness meditation on specific markers of inflammation, cell‐mediated immunity, and biological aging”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
randomised controlled trial
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-applicable
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/26799456/ · https://doi.org/10.1111/nyas.12998 · https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.12998

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    language:iv
    title
    Mindfulness and related practices: IL-6, inflammation and mental health
    collection
    language
    trust Score
    2
  2. key
    language:vii
    title
    Mindfulness and meditation: brain function and clinical outcomes
    collection
    language
    trust Score
    3
Citation snapshot and identifiers
id
pmid-26799456
doi
10.1111/nyas.12998
pmid
26799456
citation Snapshot
Not recorded
citations By Collection
language
310
Complete approved library record
id
pmid-26799456
publication Key
Not recorded
aliases
None recorded
title
Mindfulness meditation and the immune system: a systematic review of randomized controlled trials
journal
Annals of the New York Academy of Sciences
neurotransmitters
None recorded
year
2016
authors
Black DS, Slavich GM.
design
randomised controlled trial
kind
Review / synthesis
identity Conflict
Not recorded
doi
10.1111/nyas.12998
pmid
26799456
urls

https://pmc.ncbi.nlm.nih.gov/articles/PMC4940234/ · https://pubmed.ncbi.nlm.nih.gov/26799456/ · https://doi.org/10.1111/nyas.12998

collections

language

categories

Molecular biomarkers · Methods & context

targets
None recorded
priority
1
quotes

“The findings suggest possible effects of mindfulness meditation on specific markers of inflammation, cell‐mediated immunity, and biological aging”

summary
limitation
citation Count
310
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-applicable
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/26799456/ · https://doi.org/10.1111/nyas.12998 · https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.12998

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
language
310
topics
  1. key
    language:iv
    title
    Mindfulness and related practices: IL-6, inflammation and mental health
    collection
    language
    trust Score
    2
  2. key
    language:vii
    title
    Mindfulness and meditation: brain function and clinical outcomes
    collection
    language
    trust Score
    3
journal Key
annalsofthenewyorkacademyofsciences
journal Label
Annals of the New York Academy of Sciences
chapter Entries
  1. id
    language-iv-pmid-26799456
    record Id
    pmid-26799456
    title
    Mindfulness meditation and the immune system: a systematic review of randomized controlled trials
    journal
    Annals of the New York Academy of Sciences
    year
    2016
    authors
    Black DS, Slavich GM.
    design
    randomised controlled trial
    urls

    https://pmc.ncbi.nlm.nih.gov/articles/PMC4940234/ · https://pubmed.ncbi.nlm.nih.gov/26799456/ · https://doi.org/10.1111/nyas.12998

    quotes
      1. text
        “The findings suggest possible effects of mindfulness meditation on specific markers of inflammation, cell‐mediated immunity, and biological aging”
        emphasis
        false
    citation Count
    310
    source Pages

    19

    targets
    None recorded
    categories

    Molecular biomarkers · Methods & context

    doi
    10.1111/nyas.12998
    pmid
    26799456
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    false
    blinding
    not-applicable
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/26799456/ · https://doi.org/10.1111/nyas.12998 · https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.12998

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    language
    chapter Number
    1
    topic Id
    iv
    topic Title
    Mindfulness and related practices: IL-6, inflammation and mental health
    trust Score
    2
  2. id
    language-vii-pmid-26799456
    record Id
    pmid-26799456
    title
    Mindfulness meditation and the immune system: a systematic review of randomized controlled trials
    journal
    Annals of the New York Academy of Sciences
    year
    2016
    authors
    Black DS, Slavich GM.
    design
    randomised controlled trial
    urls

    https://pmc.ncbi.nlm.nih.gov/articles/PMC4940234/ · https://pubmed.ncbi.nlm.nih.gov/26799456/ · https://doi.org/10.1111/nyas.12998

    quotes
    None recorded
    citation Count
    Not recorded
    source Pages

    30

    targets
    None recorded
    categories

    Molecular biomarkers · Methods & context

    doi
    10.1111/nyas.12998
    pmid
    26799456
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    false
    blinding
    not-applicable
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/26799456/ · https://doi.org/10.1111/nyas.12998 · https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.12998

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    language
    chapter Number
    2
    topic Id
    vii
    topic Title
    Mindfulness and meditation: brain function and clinical outcomes
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

2 · 3

full Text
status
reuse-review
retrieval Available
false
url
https://pmc-oa-opendata.s3.amazonaws.com/PMC4940234.1/PMC4940234.1.xml?md5=9996ef5369b6f8d668acd2ce09653a98
pmcid
PMC4940234
rights
license
TDM
use
Private text mining
public Fulltext Redistribution
false
provider Upload
false
model Training
false
basis
https://pmc.ncbi.nlm.nih.gov/tools/pmcaws/
article Rights

This file is available for text mining. It may also be used consistent with the principles of fair use under the copyright law.

sha256
40f563122720ca3cb0933227f54f4a56a00cb40dc7c06f3389a1f3bc8e0aa9e3
checked At
2026-10-24

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