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Oxytocin receptor gene polymorphism modulates the effects of social support on heart rate variability

Kanthak MK, Chen FS, Kumsta R, Hill LK, Thayer JF, Heinrichs M. · Biological psychology · 2016

Original publication · Original publication · Original publication

Attributed extracts from the research record

“Oxytocin receptor gene polymorphism modulates effects of social support in the context of stress.”
“Social support increases HRV only in carriers of at least one G allele of rs53576.”
“Social support influences HRV specifically during direct social interaction.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/26903384/ · https://doi.org/10.1016/j.biopsycho.2016.02.007 · https://www.sciencedirect.com/science/article/abs/pii/S0301051116300357

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xxx
    title
    OXTR variation and psychological resources
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxx
    title
    OXTR variation and psychological resources
    collection
    general
    trust Score
    1
Citation snapshot and identifiers
id
pmid-26903384
doi
10.1016/j.biopsycho.2016.02.007
pmid
26903384
citation Snapshot
Not recorded
citations By Collection
sound
23
general
23
Complete approved library record
id
pmid-26903384
publication Key
Not recorded
aliases
None recorded
title
Oxytocin receptor gene polymorphism modulates the effects of social support on heart rate variability
journal
Biological psychology
neurotransmitters
None recorded
year
2016
authors
Kanthak MK, Chen FS, Kumsta R, Hill LK, Thayer JF, Heinrichs M.
design
kind
Journal article
identity Conflict
Not recorded
doi
10.1016/j.biopsycho.2016.02.007
pmid
26903384
urls

https://doi.org/10.1016/j.biopsycho.2016.02.007 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5317103/ · https://pubmed.ncbi.nlm.nih.gov/26903384/

collections

sound · general

categories

Genetics & genomics · Molecular biomarkers · Heart rate & autonomic

targets

OXTR · OXT

priority
0
quotes

“Oxytocin receptor gene polymorphism modulates effects of social support in the context of stress.” · “Social support increases HRV only in carriers of at least one G allele of rs53576.” · “Social support influences HRV specifically during direct social interaction.”

summary
limitation
citation Count
23
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/26903384/ · https://doi.org/10.1016/j.biopsycho.2016.02.007 · https://www.sciencedirect.com/science/article/abs/pii/S0301051116300357

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
23
general
23
topics
  1. key
    sound:xxx
    title
    OXTR variation and psychological resources
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxx
    title
    OXTR variation and psychological resources
    collection
    general
    trust Score
    1
journal Key
biologicalpsychology
journal Label
Biological psychology
chapter Entries
  1. id
    xxx-pmid-26903384
    record Id
    pmid-26903384
    title
    Oxytocin receptor gene polymorphism modulates the effects of social support on heart rate variability
    journal
    Biological psychology
    year
    2016
    authors
    Kanthak MK, Chen FS, Kumsta R, Hill LK, Thayer JF, Heinrichs M.
    design
    urls

    https://doi.org/10.1016/j.biopsycho.2016.02.007 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5317103/ · https://pubmed.ncbi.nlm.nih.gov/26903384/

    quotes
      1. text
        “Oxytocin receptor gene polymorphism modulates effects of social support in the context of stress.”
        emphasis
        false
      1. text
        “Social support increases HRV only in carriers of at least one G allele of rs53576.”
        emphasis
        false
      1. text
        “Social support influences HRV specifically during direct social interaction.”
        emphasis
        false
    citation Count
    23
    source Pages

    121

    targets

    OXTR · OXT

    categories

    Genetics & genomics · Molecular biomarkers · Heart rate & autonomic

    doi
    10.1016/j.biopsycho.2016.02.007
    pmid
    26903384
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/26903384/ · https://doi.org/10.1016/j.biopsycho.2016.02.007 · https://www.sciencedirect.com/science/article/abs/pii/S0301051116300357

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    6
    topic Id
    xxx
    topic Title
    OXTR variation and psychological resources
    trust Score
    1
  2. id
    general-xxx-pmid-26903384
    record Id
    pmid-26903384
    title
    Oxytocin receptor gene polymorphism modulates the effects of social support on heart rate variability
    journal
    Biological psychology
    year
    2016
    authors
    Kanthak MK, Chen FS, Kumsta R, Hill LK, Thayer JF, Heinrichs M.
    design
    urls

    https://doi.org/10.1016/j.biopsycho.2016.02.007 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5317103/ · https://pubmed.ncbi.nlm.nih.gov/26903384/

    quotes
      1. text
        “Oxytocin receptor gene polymorphism modulates effects of social support in the context of stress.”
        emphasis
        false
      1. text
        “Social support increases HRV only in carriers of at least one G allele of rs53576.”
        emphasis
        false
      1. text
        “Social support influences HRV specifically during direct social interaction.”
        emphasis
        false
    citation Count
    23
    source Pages

    121

    targets

    OXTR · OXT

    categories

    Genetics & genomics · Molecular biomarkers · Heart rate & autonomic

    doi
    10.1016/j.biopsycho.2016.02.007
    pmid
    26903384
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/26903384/ · https://doi.org/10.1016/j.biopsycho.2016.02.007 · https://www.sciencedirect.com/science/article/abs/pii/S0301051116300357

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    1
    topic Id
    sound-xxx
    topic Title
    OXTR variation and psychological resources
    trust Score
    1
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

1

full Text
status
reuse-review
retrieval Available
false
url
https://pmc-oa-opendata.s3.amazonaws.com/PMC5317103.1/PMC5317103.1.xml?md5=181d897c7d6d9e1ea25a0ca7b68b54f0
pmcid
PMC5317103
rights
license
TDM
use
Private text mining
public Fulltext Redistribution
false
provider Upload
false
model Training
false
basis
https://pmc.ncbi.nlm.nih.gov/tools/pmcaws/
article Rights

This file is available for text mining. It may also be used consistent with the principles of fair use under the copyright law.

sha256
89ff9c6bfdab0381e5f310a8d877a50130a22c1fbdc91ef760bed614b681b093
checked At
2026-10-24

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