Effects of oxytocin administration on spirituality and emotional responses to meditation
Van Cappellen P, Way BM, Isgett SF, Fredrickson BL. · Social cognitive and affective neuroscience · 2016
Original publication · Original publication · Original publication
Attributed extracts from the research record
“the effect of oxytocin on spirituality was moderated by oxytocin-related genotypes.”
“participants were also genotyped for polymorphisms in two genes critical for oxytocin signaling, the oxytocin receptor gene ( OXTR rs53576) and CD38 (rs6449182 and rs3796863).”
“These results provide the first experimental evidence that spirituality, endorsed by millions worldwide, appears to be supported by oxytocin.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/27317929/ · https://doi.org/10.1093/scan/nsw078 · https://academic.oup.com/scan/article/11/10/1579/2413952
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- language:iii
- title
- Oxytocin, OXTR variation and responses to meditation
- collection
- language
- trust Score
- 1
- key
- general:language-iii
- title
- Oxytocin, OXTR variation and responses to meditation
- collection
- general
- trust Score
- 1
Citation snapshot and identifiers
- id
- pmid-27317929
- doi
- 10.1093/scan/nsw078
- pmid
- 27317929
- citation Snapshot
- Not recorded
- citations By Collection
- language
- 44
- general
- 44
Complete approved library record
- id
- pmid-27317929
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Effects of oxytocin administration on spirituality and emotional responses to meditation
- journal
- Social cognitive and affective neuroscience
- neurotransmitters
- None recorded
- year
- 2016
- authors
- Van Cappellen P, Way BM, Isgett SF, Fredrickson BL.
- design
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1093/scan/nsw078
- pmid
- 27317929
- urls
https://pmc.ncbi.nlm.nih.gov/articles/PMC5040919/ · https://pubmed.ncbi.nlm.nih.gov/27317929/ · https://doi.org/10.1093/scan/nsw078
- collections
language · general
- categories
Genetics & genomics · Molecular biomarkers
- targets
OXTR · OXT · CD38
- priority
- 0
- quotes
“the effect of oxytocin on spirituality was moderated by oxytocin-related genotypes.” · “participants were also genotyped for polymorphisms in two genes critical for oxytocin signaling, the oxytocin receptor gene ( OXTR rs53576) and CD38 (rs6449182 and rs3796863).” · “These results provide the first experimental evidence that spirituality, endorsed by millions worldwide, appears to be supported by oxytocin.”
- summary
- limitation
- citation Count
- 44
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/27317929/ · https://doi.org/10.1093/scan/nsw078 · https://academic.oup.com/scan/article/11/10/1579/2413952
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 44
- general
- 44
- topics
- key
- language:iii
- title
- Oxytocin, OXTR variation and responses to meditation
- collection
- language
- trust Score
- 1
- key
- general:language-iii
- title
- Oxytocin, OXTR variation and responses to meditation
- collection
- general
- trust Score
- 1
- journal Key
- socialcognitiveandaffectiveneuroscience
- journal Label
- Social cognitive and affective neuroscience
- chapter Entries
- id
- language-iii-pmid-27317929
- record Id
- pmid-27317929
- title
- Effects of oxytocin administration on spirituality and emotional responses to meditation
- journal
- Social cognitive and affective neuroscience
- year
- 2016
- authors
- Van Cappellen P, Way BM, Isgett SF, Fredrickson BL.
- design
- urls
https://pmc.ncbi.nlm.nih.gov/articles/PMC5040919/ · https://pubmed.ncbi.nlm.nih.gov/27317929/ · https://doi.org/10.1093/scan/nsw078
- quotes
- text
- “the effect of oxytocin on spirituality was moderated by oxytocin-related genotypes.”
- emphasis
- false
- text
- “participants were also genotyped for polymorphisms in two genes critical for oxytocin signaling, the oxytocin receptor gene ( OXTR rs53576) and CD38 (rs6449182 and rs3796863).”
- emphasis
- false
- text
- “These results provide the first experimental evidence that spirituality, endorsed by millions worldwide, appears to be supported by oxytocin.”
- emphasis
- false
- citation Count
- 44
- source Pages
17
- targets
OXTR · OXT · CD38
- categories
Genetics & genomics · Molecular biomarkers
- doi
- 10.1093/scan/nsw078
- pmid
- 27317929
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/27317929/ · https://doi.org/10.1093/scan/nsw078 · https://academic.oup.com/scan/article/11/10/1579/2413952
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- language
- chapter Number
- 1
- topic Id
- iii
- topic Title
- Oxytocin, OXTR variation and responses to meditation
- trust Score
- 1
- id
- general-language-iii-pmid-27317929
- record Id
- pmid-27317929
- title
- Effects of oxytocin administration on spirituality and emotional responses to meditation
- journal
- Social cognitive and affective neuroscience
- year
- 2016
- authors
- Van Cappellen P, Way BM, Isgett SF, Fredrickson BL.
- design
- urls
https://pmc.ncbi.nlm.nih.gov/articles/PMC5040919/ · https://pubmed.ncbi.nlm.nih.gov/27317929/ · https://doi.org/10.1093/scan/nsw078
- quotes
- text
- “the effect of oxytocin on spirituality was moderated by oxytocin-related genotypes.”
- emphasis
- false
- text
- “participants were also genotyped for polymorphisms in two genes critical for oxytocin signaling, the oxytocin receptor gene ( OXTR rs53576) and CD38 (rs6449182 and rs3796863).”
- emphasis
- false
- text
- “These results provide the first experimental evidence that spirituality, endorsed by millions worldwide, appears to be supported by oxytocin.”
- emphasis
- false
- citation Count
- 44
- source Pages
17
- targets
OXTR · OXT · CD38
- categories
Genetics & genomics · Molecular biomarkers
- doi
- 10.1093/scan/nsw078
- pmid
- 27317929
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/27317929/ · https://doi.org/10.1093/scan/nsw078 · https://academic.oup.com/scan/article/11/10/1579/2413952
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- general
- chapter Number
- 1
- topic Id
- language-iii
- topic Title
- Oxytocin, OXTR variation and responses to meditation
- trust Score
- 1
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
1
- full Text
- status
- not-indexed
- retrieval Available
- false