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Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels

Li C, Hou L, Chen D, Lin F, Chang T, Li M, Zhang L, Niu X, Wang H, Fu S, Zheng J. · American journal of translational research · 2017

Original publication · Original publication

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/28386342/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    language:vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    language
    trust Score
    3
  2. key
    general:language-vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    general
    trust Score
    3
Citation snapshot and identifiers
id
pmid-28386342
doi
Not recorded
pmid
28386342
citation Snapshot
Not recorded
citations By Collection
language
17
general
17
Complete approved library record
id
pmid-28386342
publication Key
Not recorded
aliases
None recorded
title
Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels
journal
American journal of translational research
neurotransmitters
None recorded
year
2017
authors
Li C, Hou L, Chen D, Lin F, Chang T, Li M, Zhang L, Niu X, Wang H, Fu S, Zheng J.
design
kind
Journal article
identity Conflict
Not recorded
doi
Not recorded
pmid
28386342
urls

https://pmc.ncbi.nlm.nih.gov/articles/PMC5376007/ · https://pubmed.ncbi.nlm.nih.gov/28386342/

collections

language · general

categories

Brain & nervous system

targets
None recorded
priority
1
quotes
None recorded
summary
limitation
citation Count
17
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/28386342/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
language
17
general
17
topics
  1. key
    language:vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    language
    trust Score
    3
  2. key
    general:language-vi
    title
    Molecular hydrogen: inflammation, cognition and gene expression
    collection
    general
    trust Score
    3
journal Key
americanjournaloftranslationalresearch
journal Label
American journal of translational research
chapter Entries
  1. id
    language-vi-pmid-28386342
    record Id
    pmid-28386342
    title
    Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels
    journal
    American journal of translational research
    year
    2017
    authors
    Li C, Hou L, Chen D, Lin F, Chang T, Li M, Zhang L, Niu X, Wang H, Fu S, Zheng J.
    design
    urls

    https://pmc.ncbi.nlm.nih.gov/articles/PMC5376007/ · https://pubmed.ncbi.nlm.nih.gov/28386342/

    quotes
    None recorded
    citation Count
    17
    source Pages

    27

    targets
    None recorded
    categories

    Brain & nervous system

    doi
    Not recorded
    pmid
    28386342
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/28386342/

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    language
    chapter Number
    1
    topic Id
    vi
    topic Title
    Molecular hydrogen: inflammation, cognition and gene expression
    trust Score
    3
  2. id
    general-language-vi-pmid-28386342
    record Id
    pmid-28386342
    title
    Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels
    journal
    American journal of translational research
    year
    2017
    authors
    Li C, Hou L, Chen D, Lin F, Chang T, Li M, Zhang L, Niu X, Wang H, Fu S, Zheng J.
    design
    urls

    https://pmc.ncbi.nlm.nih.gov/articles/PMC5376007/ · https://pubmed.ncbi.nlm.nih.gov/28386342/

    quotes
    None recorded
    citation Count
    17
    source Pages

    27

    targets
    None recorded
    categories

    Brain & nervous system

    doi
    Not recorded
    pmid
    28386342
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/28386342/

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    3
    topic Id
    language-vi
    topic Title
    Molecular hydrogen: inflammation, cognition and gene expression
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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