Universal Informatics · Research reading room

Oxytocin Mobilizes Midbrain Dopamine toward Sociality

Charlet A, Grinevich V. · Neuron · 2017

Original publication · Original publication

Attributed extracts from the research record

“Oxytocin and dopamine possess significant overlap in the modulation of life-essential behaviors. Here, Xiao et al. (2017) show that the activity of dopamine neurons of the ventral tegmental area and the substantia nigra is finely tuned by axonal release of oxytocin.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-applicable
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/28728017/ · https://doi.org/10.1016/j.neuron.2017.07.002 · https://www.sciencedirect.com/science/article/pii/S0896627317306049

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    general
    trust Score
    1
Citation snapshot and identifiers
id
pmid-28728017
doi
10.1016/j.neuron.2017.07.002
pmid
28728017
citation Snapshot
Not recorded
citations By Collection
sound
13
general
13
Complete approved library record
id
pmid-28728017
publication Key
Not recorded
aliases
None recorded
title
Oxytocin Mobilizes Midbrain Dopamine toward Sociality
journal
Neuron
neurotransmitters
None recorded
year
2017
authors
Charlet A, Grinevich V.
design
kind
Review / synthesis
identity Conflict
Not recorded
doi
10.1016/j.neuron.2017.07.002
pmid
28728017
urls

https://doi.org/10.1016/j.neuron.2017.07.002 · https://pubmed.ncbi.nlm.nih.gov/28728017/

collections

sound · general

categories

Molecular biomarkers · Brain & nervous system

targets

OXT

priority
1
quotes

“Oxytocin and dopamine possess significant overlap in the modulation of life-essential behaviors. Here, Xiao et al. (2017) show that the activity of dopamine neurons of the ventral tegmental area and the substantia nigra is finely tuned by axonal release of oxytocin.”

summary
limitation
citation Count
13
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
false
blinding
not-applicable
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/28728017/ · https://doi.org/10.1016/j.neuron.2017.07.002 · https://www.sciencedirect.com/science/article/pii/S0896627317306049

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
13
general
13
topics
  1. key
    sound:xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxix
    title
    Oxytocin pathways, dopamine and serotonin
    collection
    general
    trust Score
    1
journal Key
neuron
journal Label
Neuron
chapter Entries
  1. id
    xxix-pmid-28728017
    record Id
    pmid-28728017
    title
    Oxytocin Mobilizes Midbrain Dopamine toward Sociality
    journal
    Neuron
    year
    2017
    authors
    Charlet A, Grinevich V.
    design
    urls

    https://doi.org/10.1016/j.neuron.2017.07.002 · https://pubmed.ncbi.nlm.nih.gov/28728017/

    quotes
      1. text
        “Oxytocin and dopamine possess significant overlap in the modulation of life-essential behaviors. Here, Xiao et al. (2017) show that the activity of dopamine neurons of the ventral tegmental area and the substantia nigra is finely tuned by axonal release of oxytocin.”
        emphasis
        false
    citation Count
    13
    source Pages

    119

    targets

    OXT

    categories

    Molecular biomarkers · Brain & nervous system

    doi
    10.1016/j.neuron.2017.07.002
    pmid
    28728017
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    false
    blinding
    not-applicable
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/28728017/ · https://doi.org/10.1016/j.neuron.2017.07.002 · https://www.sciencedirect.com/science/article/pii/S0896627317306049

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    6
    topic Id
    xxix
    topic Title
    Oxytocin pathways, dopamine and serotonin
    trust Score
    1
  2. id
    general-xxix-pmid-28728017
    record Id
    pmid-28728017
    title
    Oxytocin Mobilizes Midbrain Dopamine toward Sociality
    journal
    Neuron
    year
    2017
    authors
    Charlet A, Grinevich V.
    design
    urls

    https://doi.org/10.1016/j.neuron.2017.07.002 · https://pubmed.ncbi.nlm.nih.gov/28728017/

    quotes
      1. text
        “Oxytocin and dopamine possess significant overlap in the modulation of life-essential behaviors. Here, Xiao et al. (2017) show that the activity of dopamine neurons of the ventral tegmental area and the substantia nigra is finely tuned by axonal release of oxytocin.”
        emphasis
        false
    citation Count
    13
    source Pages

    119

    targets

    OXT

    categories

    Molecular biomarkers · Brain & nervous system

    doi
    10.1016/j.neuron.2017.07.002
    pmid
    28728017
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    false
    blinding
    not-applicable
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/28728017/ · https://doi.org/10.1016/j.neuron.2017.07.002 · https://www.sciencedirect.com/science/article/pii/S0896627317306049

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    1
    topic Id
    sound-xxix
    topic Title
    Oxytocin pathways, dopamine and serotonin
    trust Score
    1
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

1

full Text
status
not-indexed
retrieval Available
false

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