Maternal DRD2, SLC6A3, and OXTR genotypes as potential moderators of the relation between maternal history of care and maternal cortisol secretion in the context of mother-infant separation
Ludmer JA, Jamieson B, Gonzalez A, Levitan R, Kennedy J, Villani V, Masellis M, Basile VS, Atkinson L. · Biological psychology · 2017
Original publication · Original publication
Attributed extracts from the research record
“Multilevel models revealed that history of care had a greater influence on maternal baseline cortisol (but not cortisol trajectory) for mothers with more plasticity alleles of SLC6A3 (10R) and OXTR (G), relative to mothers with fewer or no plasticity alleles.”
“OXTR moderates between maternal history of care and cortisol during infant stress.”
“SLC6A3 moderates between maternal history of care and cortisol during infant stress.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/28890000/ · https://doi.org/10.1016/j.biopsycho.2017.09.004 · https://www.sciencedirect.com/science/article/abs/pii/S0301051117302338
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- sound:xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- sound
- trust Score
- 1
- key
- general:sound-xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- general
- trust Score
- 1
Citation snapshot and identifiers
- id
- pmid-28890000
- doi
- 10.1016/j.biopsycho.2017.09.004
- pmid
- 28890000
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- 5
- general
- 5
Complete approved library record
- id
- pmid-28890000
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Maternal DRD2, SLC6A3, and OXTR genotypes as potential moderators of the relation between maternal history of care and maternal cortisol secretion in the context of mother-infant separation
- journal
- Biological psychology
- neurotransmitters
- None recorded
- year
- 2017
- authors
- Ludmer JA, Jamieson B, Gonzalez A, Levitan R, Kennedy J, Villani V, Masellis M, Basile VS, Atkinson L.
- design
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1016/j.biopsycho.2017.09.004
- pmid
- 28890000
- urls
https://doi.org/10.1016/j.biopsycho.2017.09.004 · https://pubmed.ncbi.nlm.nih.gov/28890000/
- collections
sound · general
- categories
Genetics & genomics · Molecular biomarkers · Methods & context
- targets
OXTR · DRD2
- priority
- 0
- quotes
“Multilevel models revealed that history of care had a greater influence on maternal baseline cortisol (but not cortisol trajectory) for mothers with more plasticity alleles of SLC6A3 (10R) and OXTR (G), relative to mothers with fewer or no plasticity alleles.” · “OXTR moderates between maternal history of care and cortisol during infant stress.” · “SLC6A3 moderates between maternal history of care and cortisol during infant stress.”
- summary
- limitation
- citation Count
- 5
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/28890000/ · https://doi.org/10.1016/j.biopsycho.2017.09.004 · https://www.sciencedirect.com/science/article/abs/pii/S0301051117302338
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 5
- general
- 5
- topics
- key
- sound:xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- sound
- trust Score
- 1
- key
- general:sound-xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- general
- trust Score
- 1
- journal Key
- biologicalpsychology
- journal Label
- Biological psychology
- chapter Entries
- id
- xxix-pmid-28890000
- record Id
- pmid-28890000
- title
- Maternal DRD2, SLC6A3, and OXTR genotypes as potential moderators of the relation between maternal history of care and maternal cortisol secretion in the context of mother-infant separation
- journal
- Biological psychology
- year
- 2017
- authors
- Ludmer JA, Jamieson B, Gonzalez A, Levitan R, Kennedy J, Villani V, Masellis M, Basile VS, Atkinson L.
- design
- urls
https://doi.org/10.1016/j.biopsycho.2017.09.004 · https://pubmed.ncbi.nlm.nih.gov/28890000/
- quotes
- text
- “Multilevel models revealed that history of care had a greater influence on maternal baseline cortisol (but not cortisol trajectory) for mothers with more plasticity alleles of SLC6A3 (10R) and OXTR (G), relative to mothers with fewer or no plasticity alleles.”
- emphasis
- false
- text
- “OXTR moderates between maternal history of care and cortisol during infant stress.”
- emphasis
- false
- text
- “SLC6A3 moderates between maternal history of care and cortisol during infant stress.”
- emphasis
- false
- citation Count
- 5
- source Pages
116
- targets
OXTR · DRD2
- categories
Genetics & genomics · Molecular biomarkers · Methods & context
- doi
- 10.1016/j.biopsycho.2017.09.004
- pmid
- 28890000
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/28890000/ · https://doi.org/10.1016/j.biopsycho.2017.09.004 · https://www.sciencedirect.com/science/article/abs/pii/S0301051117302338
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- sound
- chapter Number
- 6
- topic Id
- xxix
- topic Title
- Oxytocin pathways, dopamine and serotonin
- trust Score
- 1
- id
- general-xxix-pmid-28890000
- record Id
- pmid-28890000
- title
- Maternal DRD2, SLC6A3, and OXTR genotypes as potential moderators of the relation between maternal history of care and maternal cortisol secretion in the context of mother-infant separation
- journal
- Biological psychology
- year
- 2017
- authors
- Ludmer JA, Jamieson B, Gonzalez A, Levitan R, Kennedy J, Villani V, Masellis M, Basile VS, Atkinson L.
- design
- urls
https://doi.org/10.1016/j.biopsycho.2017.09.004 · https://pubmed.ncbi.nlm.nih.gov/28890000/
- quotes
- text
- “Multilevel models revealed that history of care had a greater influence on maternal baseline cortisol (but not cortisol trajectory) for mothers with more plasticity alleles of SLC6A3 (10R) and OXTR (G), relative to mothers with fewer or no plasticity alleles.”
- emphasis
- false
- text
- “OXTR moderates between maternal history of care and cortisol during infant stress.”
- emphasis
- false
- text
- “SLC6A3 moderates between maternal history of care and cortisol during infant stress.”
- emphasis
- false
- citation Count
- 5
- source Pages
116
- targets
OXTR · DRD2
- categories
Genetics & genomics · Molecular biomarkers · Methods & context
- doi
- 10.1016/j.biopsycho.2017.09.004
- pmid
- 28890000
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/28890000/ · https://doi.org/10.1016/j.biopsycho.2017.09.004 · https://www.sciencedirect.com/science/article/abs/pii/S0301051117302338
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- general
- chapter Number
- 1
- topic Id
- sound-xxix
- topic Title
- Oxytocin pathways, dopamine and serotonin
- trust Score
- 1
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
1
- full Text
- status
- not-indexed
- retrieval Available
- false