Dataset on gene expression in the elderly after Mindfulness Awareness Practice or Health Education Program.
Lim HW, Saw WY, Feng L, Lee YK, Mahendran R, Cheah IK, Rawtaer I, Kumar AP, Kua EH, Mahendran R, Tan EC. · Data in brief · 2018 · Gene-expression dataset from a randomized trial
Original publication · Original publication · Original publication
Recorded summary
A blood gene-expression dataset from 60 older adults with mild cognitive impairment compares mindful-awareness practice with health education over nine months. It provides a reusable resource for analysing intervention-associated molecular patterns.
Recorded limitations
This is a data publication, not independent proof of a successful clinical or molecular effect. Participant overlap with associated trial reports must be retained in any synthesis.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Gene-expression dataset from a randomized trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Mindful-awareness practice
- comparator
- Health education
- evidence Type
- Gene expression
- source URLs
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- checked At
- 2026-10-26
- review Scope
- Abstract, full-text study design and GEO accession checked; independent reanalysis and comprehensive risk-of-bias assessment pending.
- discovery Sources
https://daytab.com/study/b42nb6s5 · https://europepmc.org/article/MED/29900257
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- measurement
- Affymetrix blood-expression microarray dataset
- measured Genes
- None recorded
- sample
- 60 older adults with mild cognitive impairment
- relationship Note
- Data publication from the mindful-awareness versus health-education trial
- dataset Accession
- GSE108215
- dataset URL
- https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108215
Topics and recorded topic scores
- key
- language:mindfulness-rna
- title
- Mindfulness interventions and gene expression
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-29900257
- doi
- 10.1016/j.dib.2018.03.086
- pmid
- 29900257
- citation Snapshot
- count
- 5
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/29900257
- citations By Collection
- language
- 5
Complete approved library record
- id
- pmid-29900257
- publication Key
- doi:10.1016/j.dib.2018.03.086
- aliases
- None recorded
- title
- Dataset on gene expression in the elderly after Mindfulness Awareness Practice or Health Education Program.
- journal
- Data in brief
- neurotransmitters
- None recorded
- year
- 2018
- authors
- Lim HW, Saw WY, Feng L, Lee YK, Mahendran R, Cheah IK, Rawtaer I, Kumar AP, Kua EH, Mahendran R, Tan EC.
- design
- Gene-expression dataset from a randomized trial
- identity Conflict
- Not recorded
- doi
- 10.1016/j.dib.2018.03.086
- pmid
- 29900257
- urls
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- collections
language
- categories
Gene expression
- targets
- None recorded
- priority
- 0
- quotes
- None recorded
- summary
- A blood gene-expression dataset from 60 older adults with mild cognitive impairment compares mindful-awareness practice with health education over nine months. It provides a reusable resource for analysing intervention-associated molecular patterns.
- limitation
- This is a data publication, not independent proof of a successful clinical or molecular effect. Participant overlap with associated trial reports must be retained in any synthesis.
- citation Count
- 5
- citation Snapshot
- count
- 5
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/29900257
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 5
- topics
- key
- language:mindfulness-rna
- title
- Mindfulness interventions and gene expression
- collection
- language
- trust Score
- 2
- journal Key
- datainbrief
- journal Label
- Data in brief
- chapter Entries
- title
- Dataset on gene expression in the elderly after Mindfulness Awareness Practice or Health Education Program.
- journal
- Data in brief
- year
- 2018
- authors
- Lim HW, Saw WY, Feng L, Lee YK, Mahendran R, Cheah IK, Rawtaer I, Kumar AP, Kua EH, Mahendran R, Tan EC.
- design
- Gene-expression dataset from a randomized trial
- urls
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- doi
- 10.1016/j.dib.2018.03.086
- pmid
- 29900257
- targets
- None recorded
- categories
Gene expression
- citation Count
- 5
- citation Snapshot
- count
- 5
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/29900257
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Mindful-awareness practice
- comparator
- Health education
- evidence Type
- Gene expression
- source URLs
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- checked At
- 2026-10-26
- review Scope
- Abstract, full-text study design and GEO accession checked; independent reanalysis and comprehensive risk-of-bias assessment pending.
- discovery Sources
https://daytab.com/study/b42nb6s5 · https://europepmc.org/article/MED/29900257
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- measurement
- Affymetrix blood-expression microarray dataset
- measured Genes
- None recorded
- sample
- 60 older adults with mild cognitive impairment
- relationship Note
- Data publication from the mindful-awareness versus health-education trial
- dataset Accession
- GSE108215
- dataset URL
- https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108215
- id
- language-mindfulness-rna-pmid-29900257
- record Id
- pmid-29900257
- quotes
- None recorded
- source Pages
- None recorded
- summary
- A blood gene-expression dataset from 60 older adults with mild cognitive impairment compares mindful-awareness practice with health education over nine months. It provides a reusable resource for analysing intervention-associated molecular patterns.
- limitation
- This is a data publication, not independent proof of a successful clinical or molecular effect. Participant overlap with associated trial reports must be retained in any synthesis.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1016/j.dib.2018.03.086
- collection
- language
- chapter Number
- 4
- topic Id
- mindfulness-rna
- topic Title
- Mindfulness interventions and gene expression
- trust Score
- 2
- evidence
- intervention
- Mindful-awareness practice
- comparator
- Health education
- evidence Type
- Gene expression
- source URLs
https://pubmed.ncbi.nlm.nih.gov/29900257/ · https://doi.org/10.1016/j.dib.2018.03.086 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5996403/
- checked At
- 2026-10-26
- review Scope
- Abstract, full-text study design and GEO accession checked; independent reanalysis and comprehensive risk-of-bias assessment pending.
- discovery Sources
https://daytab.com/study/b42nb6s5 · https://europepmc.org/article/MED/29900257
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- measurement
- Affymetrix blood-expression microarray dataset
- measured Genes
- None recorded
- sample
- 60 older adults with mild cognitive impairment
- relationship Note
- Data publication from the mindful-awareness versus health-education trial
- dataset Accession
- GSE108215
- dataset URL
- https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108215
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false