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Oxytocin Enhancement of Emotional Empathy: Generalization Across Cultures and Effects on Amygdala Activity

Geng Y, Zhao W, Zhou F, Ma X, Yao S, Hurlemann R, Becker B, Kendrick KM. · Frontiers in Neuroscience · 2018

Original publication · Original publication · Original publication

Attributed extracts from the research record

“Overall, our findings provide further support for the role of OXT in facilitating emotional empathy and demonstrate that effects are independent of culture and sex and involve modulatory effects on the amygdala and its interactions with other key empathy regions.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/30108475/ · https://doi.org/10.3389/fnins.2018.00512 · https://www.frontiersin.org/articles/10.3389/fnins.2018.00512/full

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    sound
    trust Score
    3
  2. key
    general:sound-xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    general
    trust Score
    3
Citation snapshot and identifiers
id
pmid-30108475
doi
10.3389/fnins.2018.00512
pmid
30108475
citation Snapshot
Not recorded
citations By Collection
sound
33
general
33
Complete approved library record
id
pmid-30108475
publication Key
Not recorded
aliases
None recorded
title
Oxytocin Enhancement of Emotional Empathy: Generalization Across Cultures and Effects on Amygdala Activity
journal
Frontiers in Neuroscience
publisher Family
frontiers
publisher Family Label
Frontiers
neurotransmitters
None recorded
year
2018
authors
Geng Y, Zhao W, Zhou F, Ma X, Yao S, Hurlemann R, Becker B, Kendrick KM.
design
kind
Journal article
identity Conflict
Not recorded
doi
10.3389/fnins.2018.00512
pmid
30108475
urls

https://www.frontiersin.org/articles/10.3389/fnins.2018.00512/full · https://doi.org/10.3389/fnins.2018.00512 · https://pmc.ncbi.nlm.nih.gov/articles/PMC6079225/

collections

sound · general

categories

Molecular biomarkers

targets

OXT

priority
1
quotes

“Overall, our findings provide further support for the role of OXT in facilitating emotional empathy and demonstrate that effects are independent of culture and sex and involve modulatory effects on the amygdala and its interactions with other key empathy regions.”

summary
limitation
citation Count
33
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/30108475/ · https://doi.org/10.3389/fnins.2018.00512 · https://www.frontiersin.org/articles/10.3389/fnins.2018.00512/full

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
33
general
33
topics
  1. key
    sound:xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    sound
    trust Score
    3
  2. key
    general:sound-xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    general
    trust Score
    3
journal Key
frontiersinneuroscience
journal Label
Frontiers in Neuroscience
chapter Entries
  1. id
    xxxi-pmid-30108475
    record Id
    pmid-30108475
    title
    Oxytocin Enhancement of Emotional Empathy: Generalization Across Cultures and Effects on Amygdala Activity
    journal
    Frontiers in Neuroscience
    year
    2018
    authors
    Geng Y, Zhao W, Zhou F, Ma X, Yao S, Hurlemann R, Becker B, Kendrick KM.
    design
    urls

    https://www.frontiersin.org/articles/10.3389/fnins.2018.00512/full · https://doi.org/10.3389/fnins.2018.00512 · https://pmc.ncbi.nlm.nih.gov/articles/PMC6079225/

    quotes
      1. text
        “Overall, our findings provide further support for the role of OXT in facilitating emotional empathy and demonstrate that effects are independent of culture and sex and involve modulatory effects on the amygdala and its interactions with other key empathy regions.”
        emphasis
        false
    citation Count
    33
    source Pages

    128

    targets

    OXT

    categories

    Molecular biomarkers

    doi
    10.3389/fnins.2018.00512
    pmid
    30108475
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/30108475/ · https://doi.org/10.3389/fnins.2018.00512 · https://www.frontiersin.org/articles/10.3389/fnins.2018.00512/full

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    6
    topic Id
    xxxi
    topic Title
    Oxytocin, empathy and intergroup relationships
    trust Score
    3
  2. id
    general-xxxi-pmid-30108475
    record Id
    pmid-30108475
    title
    Oxytocin Enhancement of Emotional Empathy: Generalization Across Cultures and Effects on Amygdala Activity
    journal
    Frontiers in Neuroscience
    year
    2018
    authors
    Geng Y, Zhao W, Zhou F, Ma X, Yao S, Hurlemann R, Becker B, Kendrick KM.
    design
    urls

    https://www.frontiersin.org/articles/10.3389/fnins.2018.00512/full · https://doi.org/10.3389/fnins.2018.00512 · https://pmc.ncbi.nlm.nih.gov/articles/PMC6079225/

    quotes
      1. text
        “Overall, our findings provide further support for the role of OXT in facilitating emotional empathy and demonstrate that effects are independent of culture and sex and involve modulatory effects on the amygdala and its interactions with other key empathy regions.”
        emphasis
        false
    citation Count
    33
    source Pages

    128

    targets

    OXT

    categories

    Molecular biomarkers

    doi
    10.3389/fnins.2018.00512
    pmid
    30108475
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/30108475/ · https://doi.org/10.3389/fnins.2018.00512 · https://www.frontiersin.org/articles/10.3389/fnins.2018.00512/full

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    1
    topic Id
    sound-xxxi
    topic Title
    Oxytocin, empathy and intergroup relationships
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

3

full Text
status
open-license
retrieval Available
true
url
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6079225/fullTextXML
pmcid
PMC6079225
rights
license
CC BY (version not specified in article)
statement

Copyright © 2018 Geng, Zhao, Zhou, Ma, Yao, Hurlemann, Becker and Kendrick. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

sha256
4058b7468d14c51f4c52527ca8f137335885775f7823fdd6620b927a7b833dad
checked At
2026-10-24

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