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Influence of various intensities of 528 Hz sound-wave in production of testosterone in rat’s brain and analysis of behavioral changes

Babayi Daylari T, Riazi GH, Pooyan S, Fathi E, Hedayati Katouli F. · Genes & genomics · 2019

Original publication · Original publication · Original publication

Attributed extracts from the research record

“sound waves with 528 Hz frequency in 100 dB intensity induce testosterone production in brain by enhancing StAR and SF-1 and reducing P450 aromatase gene expression.”
“Frequency of 528 Hz also reduces total concentration of reactive oxidative species in brain tissue.”
“Prolonged exposure to this sound wave showed reduction of anxiety related behaviors in rats. The results reveal that reduced anxiety is related to increased concentration of testosterone in brain. This study may lead to ascertain a possible therapy in which sounds may be utilized to reduce anxiety in individual.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/30414050/ · https://doi.org/10.1007/s13258-018-0753-6 · https://link.springer.com/article/10.1007/s13258-018-0753-6

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:ii
    title
    528 Hz sound: gene expression, hormonal responses and cell studies
    collection
    sound
    trust Score
    Not recorded
Citation snapshot and identifiers
id
pmid-30414050
doi
10.1007/s13258-018-0753-6
pmid
30414050
citation Snapshot
Not recorded
citations By Collection
sound
Not recorded
general
Not recorded
Complete approved library record
id
pmid-30414050
publication Key
Not recorded
aliases
None recorded
source References
  1. ref
    NPL-107
    record Id
    pmid-30414050
    source Type
    Journal publication
    title
    Influence of various intensities of 528 Hz sound-wave in production of testosterone in rat's brain and analysis of behavioral changes.
    authors
    Babayi Daylari T, Riazi GH, Pooyan S, Fathi E, Hedayati Katouli F.
    year
    2019
    journal
    Genes & genomics
    doi
    10.1007/s13258-018-0753-6
    pmid
    30414050
    pmcid
    Not recorded
    patent Number
    Not recorded
    original Assignee
    Not recorded
    original Citation
    Babayi Daylari M et al. (2019). "Influence of various intensities of 528 Hz sound-wave in production of testosterone in rat's brain and analysis of behavioral changes." Genes & Genomics (Springer)
    original Section
    528 Hz Sound Frequency and Oxytocin Modulation
    metadata Status
    metadata-matched
    claim Review
    Not independently appraised
    source URL
    https://www.notion.so/3807b9c99c5680599be7d8337c817b15
    publication URL
    https://pubmed.ncbi.nlm.nih.gov/30414050/
    metadata URL
    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22Influence+of+various+intensities+of+528+Hz+sound-wave+in+production+of+testosterone+in+rat%27s+brain+and+analysis+of+behavioral+changes%22&format=json&resultType=core&pageSize=4
    corrections
    None recorded
    topic Id
    Not recorded
    role
    Related context in complete bibliography
source Type
Journal publication
source Verification
Bibliographic metadata matched; scientific claims await appraisal.
source Collection
Hyperspectral Imaging · patent section 2.4
title
Influence of various intensities of 528 Hz sound-wave in production of testosterone in rat’s brain and analysis of behavioral changes
journal
Genes & genomics
neurotransmitters
None recorded
year
2019
authors
Babayi Daylari T, Riazi GH, Pooyan S, Fathi E, Hedayati Katouli F.
design
kind
Journal article
identity Conflict
Not recorded
doi
10.1007/s13258-018-0753-6
pmid
30414050
urls

https://link.springer.com/article/10.1007/s13258-018-0753-6 · https://doi.org/10.1007/s13258-018-0753-6 · https://pubmed.ncbi.nlm.nih.gov/30414050/

collections

sound · general

categories

Gene expression · Brain & nervous system · Clinical & self-report

targets
None recorded
priority
0
quotes

“sound waves with 528 Hz frequency in 100 dB intensity induce testosterone production in brain by enhancing StAR and SF-1 and reducing P450 aromatase gene expression.” · “Frequency of 528 Hz also reduces total concentration of reactive oxidative species in brain tissue.” · “Prolonged exposure to this sound wave showed reduction of anxiety related behaviors in rats. The results reveal that reduced anxiety is related to increased concentration of testosterone in brain. This study may lead to ascertain a possible therapy in which sounds may be utilized to reduce anxiety in individual.”

summary
limitation
citation Count
Not recorded
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/30414050/ · https://doi.org/10.1007/s13258-018-0753-6 · https://link.springer.com/article/10.1007/s13258-018-0753-6

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
Not recorded
general
Not recorded
topics
  1. key
    sound:ii
    title
    528 Hz sound: gene expression, hormonal responses and cell studies
    collection
    sound
    trust Score
    Not recorded
journal Key
genesandgenomics
journal Label
Genes & genomics
chapter Entries
  1. id
    ii-pmid-30414050
    record Id
    pmid-30414050
    title
    Influence of various intensities of 528 Hz sound-wave in production of testosterone in rat’s brain and analysis of behavioral changes
    journal
    Genes & genomics
    year
    2019
    authors
    Babayi Daylari T, Riazi GH, Pooyan S, Fathi E, Hedayati Katouli F.
    design
    urls

    https://link.springer.com/article/10.1007/s13258-018-0753-6 · https://doi.org/10.1007/s13258-018-0753-6 · https://pubmed.ncbi.nlm.nih.gov/30414050/

    quotes
      1. text
        “sound waves with 528 Hz frequency in 100 dB intensity induce testosterone production in brain by enhancing StAR and SF-1 and reducing P450 aromatase gene expression.”
        emphasis
        false
      1. text
        “Frequency of 528 Hz also reduces total concentration of reactive oxidative species in brain tissue.”
        emphasis
        false
      1. text
        “Prolonged exposure to this sound wave showed reduction of anxiety related behaviors in rats. The results reveal that reduced anxiety is related to increased concentration of testosterone in brain. This study may lead to ascertain a possible therapy in which sounds may be utilized to reduce anxiety in individual.”
        emphasis
        false
    citation Count
    Not recorded
    source Pages

    15

    targets
    None recorded
    categories

    Gene expression · Brain & nervous system · Clinical & self-report

    doi
    10.1007/s13258-018-0753-6
    pmid
    30414050
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/30414050/ · https://doi.org/10.1007/s13258-018-0753-6 · https://link.springer.com/article/10.1007/s13258-018-0753-6

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    1
    topic Id
    ii
    topic Title
    528 Hz sound: gene expression, hormonal responses and cell studies
    trust Score
    Not recorded
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores
None recorded
full Text
status
not-indexed
retrieval Available
false

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