Intranasal oxytocin increases heart-rate variability in men at clinical high risk for psychosis: a proof-of-concept study
Martins D, Davies C, De Micheli A, Oliver D, Krawczun-Rygmaczewska A, Fusar-Poli P, Paloyelis Y. · Translational Psychiatry · 2020
Original publication · Original publication · Original publication
Attributed extracts from the research record
“Autonomic nervous system (ANS) dysfunction (i.e., increased sympathetic and/or decreased parasympathetic activity) has been proposed to contribute to psychosis vulnerability.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/32655132/ · https://doi.org/10.1038/s41398-020-00890-7 · https://www.nature.com/articles/s41398-020-00890-7
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- sound:ix
- title
- Baroreflex, heart-rate variability and Mayer waves around 0.1 Hz
- collection
- sound
- trust Score
- 1
Citation snapshot and identifiers
- id
- pmid-32655132
- doi
- 10.1038/s41398-020-00890-7
- pmid
- 32655132
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- 1
Complete approved library record
- id
- pmid-32655132
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Intranasal oxytocin increases heart-rate variability in men at clinical high risk for psychosis: a proof-of-concept study
- journal
- Translational Psychiatry
- publisher Family
- nature
- publisher Family Label
- Nature Portfolio
- neurotransmitters
- None recorded
- year
- 2020
- authors
- Martins D, Davies C, De Micheli A, Oliver D, Krawczun-Rygmaczewska A, Fusar-Poli P, Paloyelis Y.
- design
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1038/s41398-020-00890-7
- pmid
- 32655132
- urls
https://www.nature.com/articles/s41398-020-00890-7 · https://doi.org/10.1038/s41398-020-00890-7 · https://pubmed.ncbi.nlm.nih.gov/32655132/
- collections
sound
- categories
Molecular biomarkers · Heart rate & autonomic
- targets
OXT
- priority
- 1
- quotes
“Autonomic nervous system (ANS) dysfunction (i.e., increased sympathetic and/or decreased parasympathetic activity) has been proposed to contribute to psychosis vulnerability.”
- summary
- limitation
- citation Count
- 1
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/32655132/ · https://doi.org/10.1038/s41398-020-00890-7 · https://www.nature.com/articles/s41398-020-00890-7
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 1
- topics
- key
- sound:ix
- title
- Baroreflex, heart-rate variability and Mayer waves around 0.1 Hz
- collection
- sound
- trust Score
- 1
- journal Key
- translationalpsychiatry
- journal Label
- Translational Psychiatry
- chapter Entries
- id
- ix-pmid-32655132
- record Id
- pmid-32655132
- title
- Intranasal oxytocin increases heart-rate variability in men at clinical high risk for psychosis: a proof-of-concept study
- journal
- Translational Psychiatry
- year
- 2020
- authors
- Martins D, Davies C, De Micheli A, Oliver D, Krawczun-Rygmaczewska A, Fusar-Poli P, Paloyelis Y.
- design
- urls
https://www.nature.com/articles/s41398-020-00890-7 · https://doi.org/10.1038/s41398-020-00890-7 · https://pubmed.ncbi.nlm.nih.gov/32655132/
- quotes
- text
- “Autonomic nervous system (ANS) dysfunction (i.e., increased sympathetic and/or decreased parasympathetic activity) has been proposed to contribute to psychosis vulnerability.”
- emphasis
- false
- citation Count
- 1
- source Pages
69
- targets
OXT
- categories
Molecular biomarkers · Heart rate & autonomic
- doi
- 10.1038/s41398-020-00890-7
- pmid
- 32655132
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/32655132/ · https://doi.org/10.1038/s41398-020-00890-7 · https://www.nature.com/articles/s41398-020-00890-7
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- sound
- chapter Number
- 2
- topic Id
- ix
- topic Title
- Baroreflex, heart-rate variability and Mayer waves around 0.1 Hz
- trust Score
- 1
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- psychosis
- evidence
- field
- title
- text
- Intranasal oxytocin increases heart-rate variability in men at clinical high risk for psychosis: a proof-of-concept study
- matched Text
- psychosis
- conditions
psychosis
- topic Trust Scores
1
- full Text
- status
- open-license
- retrieval Available
- true
- url
- https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7354990/fullTextXML
- pmcid
- PMC7354990
- rights
- license
- http://creativecommons.org/licenses/by/4.0/
- statement
© The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/ Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ .
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- 722b1c605eadddc804dd6628c2cd2c8802a2c17ccb21322b443bde66cbaaa6f6
- checked At
- 2026-10-24