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Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups

Butovskaya M, Rostovtseva V, Butovskaya P, Burkova V, Dronova D, Filatova V, Sukhodolskaya E, Vasiliev V, Mesa T, Rosa A, Lazebny O. · Journal of physiological anthropology · 2020

Original publication · Original publication · Original publication

Attributed extracts from the research record

“Our data suggest that both oxytocin (OXTR gene polymorphism) and fetal testosterone (2D:4D) may significantly affect emotional (anger) and cognitive (hostility) aggression in humans, given the leveling the role of culture.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
assessment
Not recorded
trust Factor
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/32795360/ · https://doi.org/10.1186/s40101-020-00232-y · https://jphysiolanthropol.biomedcentral.com/articles/10.1186/s40101-020-00232-y

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xxx
    title
    OXTR variation and psychological resources
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxx
    title
    OXTR variation and psychological resources
    collection
    general
    trust Score
    1
Citation snapshot and identifiers
id
pmid-32795360
doi
10.1186/s40101-020-00232-y
pmid
32795360
citation Snapshot
Not recorded
citations By Collection
sound
1
general
1
Complete approved library record
id
pmid-32795360
publication Key
Not recorded
aliases
None recorded
title
Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups
journal
Journal of physiological anthropology
neurotransmitters
None recorded
year
2020
authors
Butovskaya M, Rostovtseva V, Butovskaya P, Burkova V, Dronova D, Filatova V, Sukhodolskaya E, Vasiliev V, Mesa T, Rosa A, Lazebny O.
design
kind
Journal article
identity Conflict
Not recorded
doi
10.1186/s40101-020-00232-y
pmid
32795360
urls

https://jphysiolanthropol.biomedcentral.com/articles/10.1186/s40101-020-00232-y · https://doi.org/10.1186/s40101-020-00232-y · https://pubmed.ncbi.nlm.nih.gov/32795360/

collections

sound · general

categories

Genetics & genomics · Molecular biomarkers · Brain & nervous system

targets

OXTR · OXT

priority
0
quotes

“Our data suggest that both oxytocin (OXTR gene polymorphism) and fetal testosterone (2D:4D) may significantly affect emotional (anger) and cognitive (hostility) aggression in humans, given the leveling the role of culture.”

summary
limitation
citation Count
1
paper Trust Assessment
score
1
scope
Paper
status
assessed
randomized Controlled Trial
Not recorded
blinding
not-confirmed
peer Reviewed
true
basis
Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
sources

https://pubmed.ncbi.nlm.nih.gov/32795360/ · https://doi.org/10.1186/s40101-020-00232-y · https://jphysiolanthropol.biomedcentral.com/articles/10.1186/s40101-020-00232-y

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
1
general
1
topics
  1. key
    sound:xxx
    title
    OXTR variation and psychological resources
    collection
    sound
    trust Score
    1
  2. key
    general:sound-xxx
    title
    OXTR variation and psychological resources
    collection
    general
    trust Score
    1
journal Key
journalofphysiologicalanthropology
journal Label
Journal of physiological anthropology
chapter Entries
  1. id
    xxx-pmid-32795360
    record Id
    pmid-32795360
    title
    Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups
    journal
    Journal of physiological anthropology
    year
    2020
    authors
    Butovskaya M, Rostovtseva V, Butovskaya P, Burkova V, Dronova D, Filatova V, Sukhodolskaya E, Vasiliev V, Mesa T, Rosa A, Lazebny O.
    design
    urls

    https://jphysiolanthropol.biomedcentral.com/articles/10.1186/s40101-020-00232-y · https://doi.org/10.1186/s40101-020-00232-y · https://pubmed.ncbi.nlm.nih.gov/32795360/

    quotes
      1. text
        “Our data suggest that both oxytocin (OXTR gene polymorphism) and fetal testosterone (2D:4D) may significantly affect emotional (anger) and cognitive (hostility) aggression in humans, given the leveling the role of culture.”
        emphasis
        false
    citation Count
    1
    source Pages

    122

    targets

    OXTR · OXT

    categories

    Genetics & genomics · Molecular biomarkers · Brain & nervous system

    doi
    10.1186/s40101-020-00232-y
    pmid
    32795360
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/32795360/ · https://doi.org/10.1186/s40101-020-00232-y · https://jphysiolanthropol.biomedcentral.com/articles/10.1186/s40101-020-00232-y

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
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    topic Title
    OXTR variation and psychological resources
    trust Score
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  2. id
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    record Id
    pmid-32795360
    title
    Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups
    journal
    Journal of physiological anthropology
    year
    2020
    authors
    Butovskaya M, Rostovtseva V, Butovskaya P, Burkova V, Dronova D, Filatova V, Sukhodolskaya E, Vasiliev V, Mesa T, Rosa A, Lazebny O.
    design
    urls

    https://jphysiolanthropol.biomedcentral.com/articles/10.1186/s40101-020-00232-y · https://doi.org/10.1186/s40101-020-00232-y · https://pubmed.ncbi.nlm.nih.gov/32795360/

    quotes
      1. text
        “Our data suggest that both oxytocin (OXTR gene polymorphism) and fetal testosterone (2D:4D) may significantly affect emotional (anger) and cognitive (hostility) aggression in humans, given the leveling the role of culture.”
        emphasis
        false
    citation Count
    1
    source Pages

    122

    targets

    OXTR · OXT

    categories

    Genetics & genomics · Molecular biomarkers · Brain & nervous system

    doi
    10.1186/s40101-020-00232-y
    pmid
    32795360
    paper Trust Assessment
    score
    1
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    Not recorded
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
    sources

    https://pubmed.ncbi.nlm.nih.gov/32795360/ · https://doi.org/10.1186/s40101-020-00232-y · https://jphysiolanthropol.biomedcentral.com/articles/10.1186/s40101-020-00232-y

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    1
    topic Id
    sound-xxx
    topic Title
    OXTR variation and psychological resources
    trust Score
    1
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

1

full Text
status
open-license
retrieval Available
true
url
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7427763/fullTextXML
pmcid
PMC7427763
rights
license
http://creativecommons.org/licenses/by/4.0/
statement

© The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ . The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/ ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

sha256
aa0f72c95a7a62e4112ca0b962bccf5a912a706a89e4daad9beaabf982d23ba6
checked At
2026-10-24

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