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Effects of the Alpha, Beta, and Gamma Binaural Beat Brain Stimulation and Short-Term Training on Simultaneously Assessed Visuospatial and Verbal Working Memories, Signal Detection Measures, Response Times, and Intrasubject Response Time Variabilities: A Within-Subject Randomized Placebo-Controlled Clinical Trial.

Rakhshan V, Hassani-Abharian P, Joghataei M, Nasehi M, Khosrowabadi R. · BioMed research international · 2022 · Randomized placebo-controlled crossover experiment

Original publication · Original publication · Original publication

Recorded summary

In 31 healthy participants, brief 10 Hz binaural stimulation improved selected visuospatial response-speed and stability measures during a working-memory task.

Recorded limitations

Effects were small and differed across sensory modalities; auditory-verbal measures did not show the same pattern. There were 155 condition sessions, not 155 independent participants, and no clinical outcome was tested.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized placebo-controlled crossover experiment
assessment
category
peer-reviewed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

assessed At
2026-10-26
registered Masking Basis
false
trust Factor
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
not-confirmed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
intervention
10, 16 and 40 Hz binaural stimulation during a cognitive task
comparator
Pure tone and silence
evidence Type
Clinical or experimental outcomes
source URLs

https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

checked At
2026-10-26
review Scope
Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
discovery Sources

https://europepmc.org/article/MED/35655482

selection Policy
Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
Citation snapshot and identifiers
id
pmid-35655482
doi
10.1155/2022/8588272
pmid
35655482
citation Snapshot
count
13
source
Europe PMC
retrieved At
2026-10-26
url
https://europepmc.org/article/MED/35655482
citations By Collection
sound
13
Complete approved library record
id
pmid-35655482
publication Key
doi:10.1155/2022/8588272
aliases
None recorded
title
Effects of the Alpha, Beta, and Gamma Binaural Beat Brain Stimulation and Short-Term Training on Simultaneously Assessed Visuospatial and Verbal Working Memories, Signal Detection Measures, Response Times, and Intrasubject Response Time Variabilities: A Within-Subject Randomized Placebo-Controlled Clinical Trial.
journal
BioMed research international
neurotransmitters
None recorded
year
2022
authors
Rakhshan V, Hassani-Abharian P, Joghataei M, Nasehi M, Khosrowabadi R.
design
Randomized placebo-controlled crossover experiment
identity Conflict
Not recorded
doi
10.1155/2022/8588272
pmid
35655482
urls

https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

collections

sound

categories

Brain & nervous system

targets
None recorded
priority
1
quotes
None recorded
summary
In 31 healthy participants, brief 10 Hz binaural stimulation improved selected visuospatial response-speed and stability measures during a working-memory task.
limitation
Effects were small and differed across sensory modalities; auditory-verbal measures did not show the same pattern. There were 155 condition sessions, not 155 independent participants, and no clinical outcome was tested.
citation Count
13
citation Snapshot
count
13
source
Europe PMC
retrieved At
2026-10-26
url
https://europepmc.org/article/MED/35655482
study Design Assessment
category
peer-reviewed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

assessed At
2026-10-26
registered Masking Basis
false
paper Trust Assessment
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
not-confirmed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
13
topics
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
journal Key
biomedresearchinternational
journal Label
BioMed research international
chapter Entries
  1. title
    Effects of the Alpha, Beta, and Gamma Binaural Beat Brain Stimulation and Short-Term Training on Simultaneously Assessed Visuospatial and Verbal Working Memories, Signal Detection Measures, Response Times, and Intrasubject Response Time Variabilities: A Within-Subject Randomized Placebo-Controlled Clinical Trial.
    journal
    BioMed research international
    year
    2022
    authors
    Rakhshan V, Hassani-Abharian P, Joghataei M, Nasehi M, Khosrowabadi R.
    design
    Randomized placebo-controlled crossover experiment
    urls

    https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

    doi
    10.1155/2022/8588272
    pmid
    35655482
    targets
    None recorded
    categories

    Brain & nervous system

    citation Count
    13
    citation Snapshot
    count
    13
    source
    Europe PMC
    retrieved At
    2026-10-26
    url
    https://europepmc.org/article/MED/35655482
    study Design Assessment
    category
    peer-reviewed
    peer Reviewed
    true
    basis
    Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
    sources

    https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

    assessed At
    2026-10-26
    registered Masking Basis
    false
    evidence
    intervention
    10, 16 and 40 Hz binaural stimulation during a cognitive task
    comparator
    Pure tone and silence
    evidence Type
    Clinical or experimental outcomes
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

    checked At
    2026-10-26
    review Scope
    Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
    discovery Sources

    https://europepmc.org/article/MED/35655482

    selection Policy
    Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
    id
    sound-i-pmid-35655482
    record Id
    pmid-35655482
    quotes
    None recorded
    source Pages
    None recorded
    summary
    In 31 healthy participants, brief 10 Hz binaural stimulation improved selected visuospatial response-speed and stability measures during a working-memory task.
    limitation
    Effects were small and differed across sensory modalities; auditory-verbal measures did not show the same pattern. There were 155 condition sessions, not 155 independent participants, and no clinical outcome was tested.
    paper Trust Assessment
    score
    2
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
    sources

    https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    publication Key
    doi:10.1155/2022/8588272
    collection
    sound
    chapter Number
    1
    topic Id
    i
    topic Title
    Brain entrainment, pain, anxiety and heart-rate variability
    trust Score
    3
evidence
intervention
10, 16 and 40 Hz binaural stimulation during a cognitive task
comparator
Pure tone and silence
evidence Type
Clinical or experimental outcomes
source URLs

https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/

checked At
2026-10-26
review Scope
Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
discovery Sources

https://europepmc.org/article/MED/35655482

selection Policy
Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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