Effects of the Alpha, Beta, and Gamma Binaural Beat Brain Stimulation and Short-Term Training on Simultaneously Assessed Visuospatial and Verbal Working Memories, Signal Detection Measures, Response Times, and Intrasubject Response Time Variabilities: A Within-Subject Randomized Placebo-Controlled Clinical Trial.
Rakhshan V, Hassani-Abharian P, Joghataei M, Nasehi M, Khosrowabadi R. · BioMed research international · 2022 · Randomized placebo-controlled crossover experiment
Original publication · Original publication · Original publication
Recorded summary
In 31 healthy participants, brief 10 Hz binaural stimulation improved selected visuospatial response-speed and stability measures during a working-memory task.
Recorded limitations
Effects were small and differed across sensory modalities; auditory-verbal measures did not show the same pattern. There were 155 condition sessions, not 155 independent participants, and no clinical outcome was tested.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized placebo-controlled crossover experiment
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- 10, 16 and 40 Hz binaural stimulation during a cognitive task
- comparator
- Pure tone and silence
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/35655482
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
- key
- sound:i
- title
- Brain entrainment, pain, anxiety and heart-rate variability
- collection
- sound
- trust Score
- 3
Citation snapshot and identifiers
- id
- pmid-35655482
- doi
- 10.1155/2022/8588272
- pmid
- 35655482
- citation Snapshot
- count
- 13
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/35655482
- citations By Collection
- sound
- 13
Complete approved library record
- id
- pmid-35655482
- publication Key
- doi:10.1155/2022/8588272
- aliases
- None recorded
- title
- Effects of the Alpha, Beta, and Gamma Binaural Beat Brain Stimulation and Short-Term Training on Simultaneously Assessed Visuospatial and Verbal Working Memories, Signal Detection Measures, Response Times, and Intrasubject Response Time Variabilities: A Within-Subject Randomized Placebo-Controlled Clinical Trial.
- journal
- BioMed research international
- neurotransmitters
- None recorded
- year
- 2022
- authors
- Rakhshan V, Hassani-Abharian P, Joghataei M, Nasehi M, Khosrowabadi R.
- design
- Randomized placebo-controlled crossover experiment
- identity Conflict
- Not recorded
- doi
- 10.1155/2022/8588272
- pmid
- 35655482
- urls
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- collections
sound
- categories
Brain & nervous system
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- In 31 healthy participants, brief 10 Hz binaural stimulation improved selected visuospatial response-speed and stability measures during a working-memory task.
- limitation
- Effects were small and differed across sensory modalities; auditory-verbal measures did not show the same pattern. There were 155 condition sessions, not 155 independent participants, and no clinical outcome was tested.
- citation Count
- 13
- citation Snapshot
- count
- 13
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/35655482
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 13
- topics
- key
- sound:i
- title
- Brain entrainment, pain, anxiety and heart-rate variability
- collection
- sound
- trust Score
- 3
- journal Key
- biomedresearchinternational
- journal Label
- BioMed research international
- chapter Entries
- title
- Effects of the Alpha, Beta, and Gamma Binaural Beat Brain Stimulation and Short-Term Training on Simultaneously Assessed Visuospatial and Verbal Working Memories, Signal Detection Measures, Response Times, and Intrasubject Response Time Variabilities: A Within-Subject Randomized Placebo-Controlled Clinical Trial.
- journal
- BioMed research international
- year
- 2022
- authors
- Rakhshan V, Hassani-Abharian P, Joghataei M, Nasehi M, Khosrowabadi R.
- design
- Randomized placebo-controlled crossover experiment
- urls
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- doi
- 10.1155/2022/8588272
- pmid
- 35655482
- targets
- None recorded
- categories
Brain & nervous system
- citation Count
- 13
- citation Snapshot
- count
- 13
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/35655482
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- 10, 16 and 40 Hz binaural stimulation during a cognitive task
- comparator
- Pure tone and silence
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/35655482
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- id
- sound-i-pmid-35655482
- record Id
- pmid-35655482
- quotes
- None recorded
- source Pages
- None recorded
- summary
- In 31 healthy participants, brief 10 Hz binaural stimulation improved selected visuospatial response-speed and stability measures during a working-memory task.
- limitation
- Effects were small and differed across sensory modalities; auditory-verbal measures did not show the same pattern. There were 155 condition sessions, not 155 independent participants, and no clinical outcome was tested.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1155/2022/8588272
- collection
- sound
- chapter Number
- 1
- topic Id
- i
- topic Title
- Brain entrainment, pain, anxiety and heart-rate variability
- trust Score
- 3
- evidence
- intervention
- 10, 16 and 40 Hz binaural stimulation during a cognitive task
- comparator
- Pure tone and silence
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/35655482/ · https://doi.org/10.1155/2022/8588272 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9153928/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/35655482
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
3
- full Text
- status
- not-indexed
- retrieval Available
- false