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The effect of binaural beat audio on anxiety in patients undergoing fiberoptic bronchoscopy: A prospective randomized controlled trial.

Opartpunyasarn P, Vichitvejpaisal P, Oer-Areemitr N. · Medicine · 2022 · Randomized controlled trial

Original publication · Original publication · Original publication

Recorded summary

Among 112 bronchoscopy patients, the binaural-music arm showed a larger numerical reduction in state anxiety than plain music or no music, with reductions in blood pressure.

Recorded limitations

The abstract mainly reports within-group changes, so those numbers alone do not establish superiority over plain music. The trial was retrospectively registered.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial
assessment
category
peer-reviewed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

assessed At
2026-10-26
registered Masking Basis
false
trust Factor
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
not-confirmed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
intervention
Binaural-beat music around bronchoscopy
comparator
Plain music and no music
evidence Type
Clinical or experimental outcomes
source URLs

https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

checked At
2026-10-26
review Scope
Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
discovery Sources

https://europepmc.org/article/MED/35713444

selection Policy
Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
Citation snapshot and identifiers
id
pmid-35713444
doi
10.1097/md.0000000000029392
pmid
35713444
citation Snapshot
count
16
source
Europe PMC
retrieved At
2026-10-26
url
https://europepmc.org/article/MED/35713444
citations By Collection
sound
16
Complete approved library record
id
pmid-35713444
publication Key
doi:10.1097/md.0000000000029392
aliases
None recorded
title
The effect of binaural beat audio on anxiety in patients undergoing fiberoptic bronchoscopy: A prospective randomized controlled trial.
journal
Medicine
neurotransmitters
None recorded
year
2022
authors
Opartpunyasarn P, Vichitvejpaisal P, Oer-Areemitr N.
design
Randomized controlled trial
identity Conflict
Not recorded
doi
10.1097/md.0000000000029392
pmid
35713444
urls

https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

collections

sound

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
Among 112 bronchoscopy patients, the binaural-music arm showed a larger numerical reduction in state anxiety than plain music or no music, with reductions in blood pressure.
limitation
The abstract mainly reports within-group changes, so those numbers alone do not establish superiority over plain music. The trial was retrospectively registered.
citation Count
16
citation Snapshot
count
16
source
Europe PMC
retrieved At
2026-10-26
url
https://europepmc.org/article/MED/35713444
study Design Assessment
category
peer-reviewed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

assessed At
2026-10-26
registered Masking Basis
false
paper Trust Assessment
score
2
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
not-confirmed
peer Reviewed
true
basis
Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
sources

https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
16
topics
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
journal Key
medicine
journal Label
Medicine
chapter Entries
  1. title
    The effect of binaural beat audio on anxiety in patients undergoing fiberoptic bronchoscopy: A prospective randomized controlled trial.
    journal
    Medicine
    year
    2022
    authors
    Opartpunyasarn P, Vichitvejpaisal P, Oer-Areemitr N.
    design
    Randomized controlled trial
    urls

    https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

    doi
    10.1097/md.0000000000029392
    pmid
    35713444
    targets
    None recorded
    categories

    Clinical & self-report

    citation Count
    16
    citation Snapshot
    count
    16
    source
    Europe PMC
    retrieved At
    2026-10-26
    url
    https://europepmc.org/article/MED/35713444
    study Design Assessment
    category
    peer-reviewed
    peer Reviewed
    true
    basis
    Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
    sources

    https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

    assessed At
    2026-10-26
    registered Masking Basis
    false
    evidence
    intervention
    Binaural-beat music around bronchoscopy
    comparator
    Plain music and no music
    evidence Type
    Clinical or experimental outcomes
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

    checked At
    2026-10-26
    review Scope
    Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
    discovery Sources

    https://europepmc.org/article/MED/35713444

    selection Policy
    Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
    id
    sound-i-pmid-35713444
    record Id
    pmid-35713444
    quotes
    None recorded
    source Pages
    None recorded
    summary
    Among 112 bronchoscopy patients, the binaural-music arm showed a larger numerical reduction in state anxiety than plain music or no music, with reductions in blood pressure.
    limitation
    The abstract mainly reports within-group changes, so those numbers alone do not establish superiority over plain music. The trial was retrospectively registered.
    paper Trust Assessment
    score
    2
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    not-confirmed
    peer Reviewed
    true
    basis
    Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
    sources

    https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    publication Key
    doi:10.1097/md.0000000000029392
    collection
    sound
    chapter Number
    1
    topic Id
    i
    topic Title
    Brain entrainment, pain, anxiety and heart-rate variability
    trust Score
    3
evidence
intervention
Binaural-beat music around bronchoscopy
comparator
Plain music and no music
evidence Type
Clinical or experimental outcomes
source URLs

https://pubmed.ncbi.nlm.nih.gov/35713444/ · https://doi.org/10.1097/md.0000000000029392 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9276398/

checked At
2026-10-26
review Scope
Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
discovery Sources

https://europepmc.org/article/MED/35713444

selection Policy
Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    anxiety
    evidence
    1. field
      curated primary-source summary
      text
      Among 112 bronchoscopy patients, the binaural-music arm showed a larger numerical reduction in state anxiety than plain music or no music, with reductions in blood pressure.
      matched Text
      anxiety
conditions

anxiety

topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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