The Effect of Binaural Beat Audio on Operative Pain and Anxiety in Cataract Surgery under Topical Anaesthesia: A Randomized Controlled Trial.
Loong LJ, Ling KK, Tai ELM, Kueh YC, Kuan G, Hussein A. · International journal of environmental research and public health · 2022 · Randomized controlled trial
Original publication · Original publication · Original publication
Recorded summary
A 61-person cataract-surgery trial reported lower operative pain, anxiety and heart rate with binaural-beat audio than with silent headphones.
Recorded limitations
A small procedure-specific study with a silence comparator. It does not separate beat effects from the effects of hearing calming audio.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Binaural-beat audio during cataract surgery
- comparator
- Silent headphones
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/h46xc47s · https://europepmc.org/article/MED/36011825
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
- key
- sound:i
- title
- Brain entrainment, pain, anxiety and heart-rate variability
- collection
- sound
- trust Score
- 3
Citation snapshot and identifiers
- id
- pmid-36011825
- doi
- 10.3390/ijerph191610194
- pmid
- 36011825
- citation Snapshot
- count
- 24
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/36011825
- citations By Collection
- sound
- 24
Complete approved library record
- id
- pmid-36011825
- publication Key
- doi:10.3390/ijerph191610194
- aliases
- None recorded
- title
- The Effect of Binaural Beat Audio on Operative Pain and Anxiety in Cataract Surgery under Topical Anaesthesia: A Randomized Controlled Trial.
- journal
- International journal of environmental research and public health
- neurotransmitters
- None recorded
- year
- 2022
- authors
- Loong LJ, Ling KK, Tai ELM, Kueh YC, Kuan G, Hussein A.
- design
- Randomized controlled trial
- identity Conflict
- Not recorded
- doi
- 10.3390/ijerph191610194
- pmid
- 36011825
- urls
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- collections
sound
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- A 61-person cataract-surgery trial reported lower operative pain, anxiety and heart rate with binaural-beat audio than with silent headphones.
- limitation
- A small procedure-specific study with a silence comparator. It does not separate beat effects from the effects of hearing calming audio.
- citation Count
- 24
- citation Snapshot
- count
- 24
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/36011825
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 24
- topics
- key
- sound:i
- title
- Brain entrainment, pain, anxiety and heart-rate variability
- collection
- sound
- trust Score
- 3
- journal Key
- internationaljournalofenvironmentalresearchandpublichealth
- journal Label
- International journal of environmental research and public health
- chapter Entries
- title
- The Effect of Binaural Beat Audio on Operative Pain and Anxiety in Cataract Surgery under Topical Anaesthesia: A Randomized Controlled Trial.
- journal
- International journal of environmental research and public health
- year
- 2022
- authors
- Loong LJ, Ling KK, Tai ELM, Kueh YC, Kuan G, Hussein A.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- doi
- 10.3390/ijerph191610194
- pmid
- 36011825
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 24
- citation Snapshot
- count
- 24
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/36011825
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Binaural-beat audio during cataract surgery
- comparator
- Silent headphones
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/h46xc47s · https://europepmc.org/article/MED/36011825
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- id
- sound-i-pmid-36011825
- record Id
- pmid-36011825
- quotes
- None recorded
- source Pages
- None recorded
- summary
- A 61-person cataract-surgery trial reported lower operative pain, anxiety and heart rate with binaural-beat audio than with silent headphones.
- limitation
- A small procedure-specific study with a silence comparator. It does not separate beat effects from the effects of hearing calming audio.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.3390/ijerph191610194
- collection
- sound
- chapter Number
- 1
- topic Id
- i
- topic Title
- Brain entrainment, pain, anxiety and heart-rate variability
- trust Score
- 3
- evidence
- intervention
- Binaural-beat audio during cataract surgery
- comparator
- Silent headphones
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/36011825/ · https://doi.org/10.3390/ijerph191610194 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9408317/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/h46xc47s · https://europepmc.org/article/MED/36011825
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- anxiety
- evidence
- field
- curated primary-source summary
- text
- A 61-person cataract-surgery trial reported lower operative pain, anxiety and heart rate with binaural-beat audio than with silent headphones.
- matched Text
- anxiety
- conditions
anxiety
- topic Trust Scores
3
- full Text
- status
- not-indexed
- retrieval Available
- false