Developmental light deprivation transiently reduces the expression of vGluT2 and GluN2B in the rat ventral suprachiasmatic nucleus
Reyes-Méndez ME, Herrera-Zamora JM, Osuna-Lopez F, Aguilar-Martínez IS, Góngora-Alfaro JL, Navarro-Polanco RA, Sánchez-Pastor E, Moreno-Galindo EG, Alamilla J. · Synapse (New York, N.Y.) · 2023 · Developmental light-deprivation experiment in rats
Original publication · Original publication
Recorded summary
Constant-darkness rearing transiently reduced vGluT2 and GluN2B expression in the ventral suprachiasmatic nucleus; the differences were compensated at later stages.
Recorded limitations
Developmental protein expression in rats is not direct evidence of human GRIN2B transcription or an adult visual therapy effect.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Developmental light-deprivation experiment in rats
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/36085433/ · https://doi.org/10.1002/syn.22250
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-36085433
- doi
- 10.1002/syn.22250
- pmid
- 36085433
- citation Snapshot
- Not recorded
- citations By Collection
- vision
- Not recorded
Complete approved library record
- id
- pmid-36085433
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Developmental light deprivation transiently reduces the expression of vGluT2 and GluN2B in the rat ventral suprachiasmatic nucleus
- journal
- Synapse (New York, N.Y.)
- neurotransmitters
- None recorded
- year
- 2023
- authors
- Reyes-Méndez ME, Herrera-Zamora JM, Osuna-Lopez F, Aguilar-Martínez IS, Góngora-Alfaro JL, Navarro-Polanco RA, Sánchez-Pastor E, Moreno-Galindo EG, Alamilla J.
- design
- Developmental light-deprivation experiment in rats
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1002/syn.22250
- pmid
- 36085433
- urls
https://pubmed.ncbi.nlm.nih.gov/36085433/ · https://doi.org/10.1002/syn.22250
- collections
vision
- categories
Molecular biomarkers · Brain & nervous system
- targets
NMDA
- priority
- 1
- quotes
- None recorded
- summary
- Constant-darkness rearing transiently reduced vGluT2 and GluN2B expression in the ventral suprachiasmatic nucleus; the differences were compensated at later stages.
- limitation
- Developmental protein expression in rats is not direct evidence of human GRIN2B transcription or an adult visual therapy effect.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/36085433/ · https://doi.org/10.1002/syn.22250
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- Not recorded
- topics
- None recorded
- journal Key
- synapse
- journal Label
- Synapse (New York, N.Y.)
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- not-indexed
- retrieval Available
- false