Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling
Hu S, Wang Y, Han X, Dai M, Zhang Y, Ma Y, Weng S, Xiao L, Xiao L. · BMC biology · 2022 · Mouse retinal molecular and physiological experiments
Original publication · Original publication
Recorded summary
Oxtr mRNA and receptor protein were detected in retinal amacrine cells. Applying oxytocin activated dopaminergic cells and altered retinal responses through receptor-dependent signalling.
Recorded limitations
This establishes a retinal signalling context. It does not show that a visual pattern changes OXTR transcription in humans.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Mouse retinal molecular and physiological experiments
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/36127701/ · https://doi.org/10.1186/s12915-022-01405-0
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-36127701
- doi
- 10.1186/s12915-022-01405-0
- pmid
- 36127701
- citation Snapshot
- Not recorded
- citations By Collection
- vision
- Not recorded
Complete approved library record
- id
- pmid-36127701
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling
- journal
- BMC biology
- neurotransmitters
- None recorded
- year
- 2022
- authors
- Hu S, Wang Y, Han X, Dai M, Zhang Y, Ma Y, Weng S, Xiao L, Xiao L.
- design
- Mouse retinal molecular and physiological experiments
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1186/s12915-022-01405-0
- pmid
- 36127701
- urls
https://doi.org/10.1186/s12915-022-01405-0 · https://pubmed.ncbi.nlm.nih.gov/36127701/
- collections
vision
- categories
Gene expression · Brain & nervous system
- targets
OXTR · OXT
- priority
- 0
- quotes
- None recorded
- summary
- Oxtr mRNA and receptor protein were detected in retinal amacrine cells. Applying oxytocin activated dopaminergic cells and altered retinal responses through receptor-dependent signalling.
- limitation
- This establishes a retinal signalling context. It does not show that a visual pattern changes OXTR transcription in humans.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/36127701/ · https://doi.org/10.1186/s12915-022-01405-0
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- Not recorded
- topics
- None recorded
- journal Key
- bmcbiology
- journal Label
- BMC biology
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- open-license
- retrieval Available
- true
- url
- https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9490981/fullTextXML
- pmcid
- PMC9490981
- rights
- license
- https://creativecommons.org/licenses/by/4.0/
- statement
© The Author(s) 2022 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ . The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/ ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
- sha256
- bf30d40e88b89bfa6395507cda1315c2e011e3ff8d113b676a631237f5e9cff6
- checked At
- 2026-10-24