Light disrupts social memory via a retina-to-supraoptic nucleus circuit
Huang YF, Liao PY, Yu JH, Chen SK. · EMBO reports · 2023 · Mouse neural-circuit experiment
Original publication · Original publication · Original publication
Recorded summary
Acute light exposure impaired social-recognition memory through a retinal pathway that inhibited supraoptic oxytocin neurons. Experimental activation of these neurons altered the behavioural response.
Recorded limitations
Neural activity and behavioural changes are separate from OXTR gene expression. The animal circuit findings do not validate a human visual intervention.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Mouse neural-circuit experiment
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/37531065/ · https://doi.org/10.15252/embr.202356839
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-37531065
- doi
- 10.15252/embr.202356839
- pmid
- 37531065
- citation Snapshot
- Not recorded
- citations By Collection
- vision
- Not recorded
Complete approved library record
- id
- pmid-37531065
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Light disrupts social memory via a retina-to-supraoptic nucleus circuit
- journal
- EMBO reports
- neurotransmitters
- None recorded
- year
- 2023
- authors
- Huang YF, Liao PY, Yu JH, Chen SK.
- design
- Mouse neural-circuit experiment
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.15252/embr.202356839
- pmid
- 37531065
- urls
https://doi.org/10.15252/embr.202356839 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10561173/ · https://pubmed.ncbi.nlm.nih.gov/37531065/
- collections
vision
- categories
Brain & nervous system
- targets
OXT
- priority
- 1
- quotes
- None recorded
- summary
- Acute light exposure impaired social-recognition memory through a retinal pathway that inhibited supraoptic oxytocin neurons. Experimental activation of these neurons altered the behavioural response.
- limitation
- Neural activity and behavioural changes are separate from OXTR gene expression. The animal circuit findings do not validate a human visual intervention.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/37531065/ · https://doi.org/10.15252/embr.202356839
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- Not recorded
- topics
- None recorded
- journal Key
- emboreports
- journal Label
- EMBO reports
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- not-indexed
- retrieval Available
- false