Effects of Sudarshan KriyaYoga and Advanced Meditation Program on Genetic Expression of Pro-inflammatory and Antioxidants Genes.
Bhaskar L, Kharya C, Debnath M, Mullapudi T, Subbanna M, Chhabra D, Kumar N, Sharma PP, Bhagat OL, Kochupillai V. · Cureus · 2023 · Nonrandomized controlled molecular study
Original publication · Original publication · Original publication
Recorded summary
Among 97 experienced practitioners, a Sudarshan Kriya Yoga retreat was associated with changes in inflammatory and antioxidant gene-expression measures, including IL6, relative to a comparison group.
Recorded limitations
Allocation was not random, and pre-pandemic and pandemic-era cohorts differed. The intervention combined breathing and meditation; it does not isolate mantra or establish general clinical benefit.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Nonrandomized controlled molecular study
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- not-applicable
- score
- Not recorded
- evidence
- intervention
- Sudarshan Kriya Yoga retreat
- comparator
- Experienced practitioners not attending the retreat
- evidence Type
- Gene expression
- source URLs
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/37546047
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- measurement
- Inflammatory and antioxidant messenger RNA
- measured Genes
IL6 · IL1B · TNF
- sample
- 97 experienced practitioners
Topics and recorded topic scores
- key
- language:mindfulness-rna
- title
- Mindfulness interventions and gene expression
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-37546047
- doi
- 10.7759/cureus.41377
- pmid
- 37546047
- citation Snapshot
- count
- 3
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/37546047
- citations By Collection
- language
- 3
Complete approved library record
- id
- pmid-37546047
- publication Key
- doi:10.7759/cureus.41377
- aliases
- None recorded
- title
- Effects of Sudarshan KriyaYoga and Advanced Meditation Program on Genetic Expression of Pro-inflammatory and Antioxidants Genes.
- journal
- Cureus
- neurotransmitters
- None recorded
- year
- 2023
- authors
- Bhaskar L, Kharya C, Debnath M, Mullapudi T, Subbanna M, Chhabra D, Kumar N, Sharma PP, Bhagat OL, Kochupillai V.
- design
- Nonrandomized controlled molecular study
- identity Conflict
- Not recorded
- doi
- 10.7759/cureus.41377
- pmid
- 37546047
- urls
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- collections
language
- categories
Gene expression
- targets
IL6 · IL1B · TNF
- priority
- 0
- quotes
- None recorded
- summary
- Among 97 experienced practitioners, a Sudarshan Kriya Yoga retreat was associated with changes in inflammatory and antioxidant gene-expression measures, including IL6, relative to a comparison group.
- limitation
- Allocation was not random, and pre-pandemic and pandemic-era cohorts differed. The intervention combined breathing and meditation; it does not isolate mantra or establish general clinical benefit.
- citation Count
- 3
- citation Snapshot
- count
- 3
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/37546047
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 3
- topics
- key
- language:mindfulness-rna
- title
- Mindfulness interventions and gene expression
- collection
- language
- trust Score
- 2
- journal Key
- cureus
- journal Label
- Cureus
- chapter Entries
- title
- Effects of Sudarshan KriyaYoga and Advanced Meditation Program on Genetic Expression of Pro-inflammatory and Antioxidants Genes.
- journal
- Cureus
- year
- 2023
- authors
- Bhaskar L, Kharya C, Debnath M, Mullapudi T, Subbanna M, Chhabra D, Kumar N, Sharma PP, Bhagat OL, Kochupillai V.
- design
- Nonrandomized controlled molecular study
- urls
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- doi
- 10.7759/cureus.41377
- pmid
- 37546047
- targets
IL6 · IL1B · TNF
- categories
Gene expression
- citation Count
- 3
- citation Snapshot
- count
- 3
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/37546047
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Sudarshan Kriya Yoga retreat
- comparator
- Experienced practitioners not attending the retreat
- evidence Type
- Gene expression
- source URLs
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/37546047
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- measurement
- Inflammatory and antioxidant messenger RNA
- measured Genes
IL6 · IL1B · TNF
- sample
- 97 experienced practitioners
- id
- language-mindfulness-rna-pmid-37546047
- record Id
- pmid-37546047
- quotes
- None recorded
- source Pages
- None recorded
- summary
- Among 97 experienced practitioners, a Sudarshan Kriya Yoga retreat was associated with changes in inflammatory and antioxidant gene-expression measures, including IL6, relative to a comparison group.
- limitation
- Allocation was not random, and pre-pandemic and pandemic-era cohorts differed. The intervention combined breathing and meditation; it does not isolate mantra or establish general clinical benefit.
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.7759/cureus.41377
- collection
- language
- chapter Number
- 4
- topic Id
- mindfulness-rna
- topic Title
- Mindfulness interventions and gene expression
- trust Score
- 2
- evidence
- intervention
- Sudarshan Kriya Yoga retreat
- comparator
- Experienced practitioners not attending the retreat
- evidence Type
- Gene expression
- source URLs
https://pubmed.ncbi.nlm.nih.gov/37546047/ · https://doi.org/10.7759/cureus.41377 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10400732/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://europepmc.org/article/MED/37546047
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- measurement
- Inflammatory and antioxidant messenger RNA
- measured Genes
IL6 · IL1B · TNF
- sample
- 97 experienced practitioners
- jadad
- status
- not-applicable
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false