Music compensates for altered gene expression in age-related cognitive disorders
Gómez-Carballa A, Navarro L, Pardo-Seco J, Bello X, Pischedda S, Viz-Lasheras S, Camino-Mera A, Currás MJ, Ferreirós I, Mallah N, Rey-Vázquez S, Redondo L, Dacosta-Urbieta A, Caamaño-Viña F, Rivero-Calle I, Rodriguez-Tenreiro C, Martinón-Torres F, Salas A. · Scientific Reports · 2023 · Human before–after transcriptomic study
Original publication · Original publication · Original publication
Recorded summary
A music session was associated with blood gene-expression changes in people with age-related cognitive disorders and healthy controls. Some affected pathways overlapped inversely with disease-associated expression patterns.
Recorded limitations
Before–after molecular associations and cross-dataset comparisons do not establish that music reverses dementia or changes brain gene expression.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Human before–after transcriptomic study
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/38040763/ · https://doi.org/10.1038/s41598-023-48094-5
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-38040763
- doi
- 10.1038/s41598-023-48094-5
- pmid
- 38040763
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- Not recorded
Complete approved library record
- id
- pmid-38040763
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Music compensates for altered gene expression in age-related cognitive disorders
- journal
- Scientific Reports
- publisher Family
- nature
- publisher Family Label
- Nature Portfolio
- neurotransmitters
- None recorded
- year
- 2023
- authors
- Gómez-Carballa A, Navarro L, Pardo-Seco J, Bello X, Pischedda S, Viz-Lasheras S, Camino-Mera A, Currás MJ, Ferreirós I, Mallah N, Rey-Vázquez S, Redondo L, Dacosta-Urbieta A, Caamaño-Viña F, Rivero-Calle I, Rodriguez-Tenreiro C, Martinón-Torres F, Salas A.
- design
- Human before–after transcriptomic study
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1038/s41598-023-48094-5
- pmid
- 38040763
- urls
https://doi.org/10.1038/s41598-023-48094-5 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10692168/ · https://pubmed.ncbi.nlm.nih.gov/38040763/
- collections
sound
- categories
Gene expression
- targets
- None recorded
- priority
- 0
- quotes
- None recorded
- summary
- A music session was associated with blood gene-expression changes in people with age-related cognitive disorders and healthy controls. Some affected pathways overlapped inversely with disease-associated expression patterns.
- limitation
- Before–after molecular associations and cross-dataset comparisons do not establish that music reverses dementia or changes brain gene expression.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/38040763/ · https://doi.org/10.1038/s41598-023-48094-5
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- Not recorded
- topics
- None recorded
- journal Key
- scientificreports
- journal Label
- Scientific Reports
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- open-license
- retrieval Available
- true
- url
- https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10692168/fullTextXML
- pmcid
- PMC10692168
- rights
- license
- https://creativecommons.org/licenses/by/4.0/
- statement
© The Author(s) 2023 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ .
- sha256
- 1e44fc3f1b1aac2873315f6cbc02823f7163fb00184f6f62357ff4c3b7bbf3ae
- checked At
- 2026-10-24