Light damage induces inflammatory factors in mouse retina and vitreous humor
Liu W, Zhu X, Ge X, Chen Y, Li DW, Gong L. · Molecular vision · 2023 · Mouse light-induced retinal injury model
Original publication · Original publication · Original publication
Recorded summary
Strong light exposure induced retinal inflammatory transcriptional changes. Vitreous IL-6 protein was approximately tenfold higher in the injury model.
Recorded limitations
The IL-6 fold change concerns vitreous protein. This is a harmful exposure model, not evidence for a therapeutic visual protocol.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Mouse light-induced retinal injury model
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/38222454/ · https://doi.org/10.5281/zenodo.7870831
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-38222454
- doi
- 10.5281/zenodo.7870831
- pmid
- 38222454
- citation Snapshot
- Not recorded
- citations By Collection
- vision
- Not recorded
Complete approved library record
- id
- pmid-38222454
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Light damage induces inflammatory factors in mouse retina and vitreous humor
- journal
- Molecular vision
- neurotransmitters
- None recorded
- year
- 2023
- authors
- Liu W, Zhu X, Ge X, Chen Y, Li DW, Gong L.
- design
- Mouse light-induced retinal injury model
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.5281/zenodo.7870831
- pmid
- 38222454
- urls
https://doi.org/10.5281/zenodo.7870831 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10784230/ · https://pubmed.ncbi.nlm.nih.gov/38222454/
- collections
vision
- categories
Gene expression · Molecular biomarkers
- targets
IL6 · TNF
- priority
- 0
- quotes
- None recorded
- summary
- Strong light exposure induced retinal inflammatory transcriptional changes. Vitreous IL-6 protein was approximately tenfold higher in the injury model.
- limitation
- The IL-6 fold change concerns vitreous protein. This is a harmful exposure model, not evidence for a therapeutic visual protocol.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/38222454/ · https://doi.org/10.5281/zenodo.7870831
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- Not recorded
- topics
- None recorded
- journal Key
- molecularvision
- journal Label
- Molecular vision
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- not-indexed
- retrieval Available
- false