Effect of Binaural Beats on Anxiety and Tolerance in Patients Undergoing Upper Gastrointestinal Endoscopy Without Sedation: A Randomized Controlled Trial.
Demirci S, Sezer S. · Journal of integrative and complementary medicine · 2024 · Randomized controlled trial
Original publication · Original publication · Original publication
Recorded summary
In 96 patients undergoing unsedated upper gastrointestinal endoscopy, binaural-beat music was associated with improved anxiety, procedure tolerance and satisfaction compared with no intervention.
Recorded limitations
The trial did not include an otherwise identical music control, so the contribution of the beats is unresolved. Blood pressure and heart rate did not differ significantly.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Binaural-beat music during endoscopy
- comparator
- No auditory intervention
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/7gtf9kh8 · https://europepmc.org/article/MED/39088370
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT06114524
Topics and recorded topic scores
- key
- sound:i
- title
- Brain entrainment, pain, anxiety and heart-rate variability
- collection
- sound
- trust Score
- 3
Citation snapshot and identifiers
- id
- pmid-39088370
- doi
- 10.1089/jicm.2023.0804
- pmid
- 39088370
- citation Snapshot
- count
- 6
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/39088370
- citations By Collection
- sound
- 6
Complete approved library record
- id
- pmid-39088370
- publication Key
- doi:10.1089/jicm.2023.0804
- aliases
- None recorded
- title
- Effect of Binaural Beats on Anxiety and Tolerance in Patients Undergoing Upper Gastrointestinal Endoscopy Without Sedation: A Randomized Controlled Trial.
- journal
- Journal of integrative and complementary medicine
- neurotransmitters
- None recorded
- year
- 2024
- authors
- Demirci S, Sezer S.
- design
- Randomized controlled trial
- identity Conflict
- Not recorded
- doi
- 10.1089/jicm.2023.0804
- pmid
- 39088370
- urls
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- collections
sound
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- In 96 patients undergoing unsedated upper gastrointestinal endoscopy, binaural-beat music was associated with improved anxiety, procedure tolerance and satisfaction compared with no intervention.
- limitation
- The trial did not include an otherwise identical music control, so the contribution of the beats is unresolved. Blood pressure and heart rate did not differ significantly.
- citation Count
- 6
- citation Snapshot
- count
- 6
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/39088370
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 6
- topics
- key
- sound:i
- title
- Brain entrainment, pain, anxiety and heart-rate variability
- collection
- sound
- trust Score
- 3
- journal Key
- journalofintegrativeandcomplementarymedicine
- journal Label
- Journal of integrative and complementary medicine
- chapter Entries
- title
- Effect of Binaural Beats on Anxiety and Tolerance in Patients Undergoing Upper Gastrointestinal Endoscopy Without Sedation: A Randomized Controlled Trial.
- journal
- Journal of integrative and complementary medicine
- year
- 2024
- authors
- Demirci S, Sezer S.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- doi
- 10.1089/jicm.2023.0804
- pmid
- 39088370
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 6
- citation Snapshot
- count
- 6
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/39088370
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Binaural-beat music during endoscopy
- comparator
- No auditory intervention
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/7gtf9kh8 · https://europepmc.org/article/MED/39088370
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT06114524
- id
- sound-i-pmid-39088370
- record Id
- pmid-39088370
- quotes
- None recorded
- source Pages
- None recorded
- summary
- In 96 patients undergoing unsedated upper gastrointestinal endoscopy, binaural-beat music was associated with improved anxiety, procedure tolerance and satisfaction compared with no intervention.
- limitation
- The trial did not include an otherwise identical music control, so the contribution of the beats is unresolved. Blood pressure and heart rate did not differ significantly.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1089/jicm.2023.0804
- collection
- sound
- chapter Number
- 1
- topic Id
- i
- topic Title
- Brain entrainment, pain, anxiety and heart-rate variability
- trust Score
- 3
- evidence
- intervention
- Binaural-beat music during endoscopy
- comparator
- No auditory intervention
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/39088370/ · https://doi.org/10.1089/jicm.2023.0804 · https://pmc.ncbi.nlm.nih.gov/articles/PMC11659431/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/7gtf9kh8 · https://europepmc.org/article/MED/39088370
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT06114524
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- anxiety
- evidence
- field
- curated primary-source summary
- text
- In 96 patients undergoing unsedated upper gastrointestinal endoscopy, binaural-beat music was associated with improved anxiety, procedure tolerance and satisfaction compared with no intervention.
- matched Text
- anxiety
- conditions
anxiety
- topic Trust Scores
3
- full Text
- status
- not-indexed
- retrieval Available
- false