Predicting psychosocial intervention response from baseline gene expression
Ricon-Becker I, West TN, Fredrickson BL, Kaplan DM, Mehl MR, Raison CL, Cole SW. · Brain, behavior, and immunity · 2024 · Prediction analyses across two randomized trials
Original publication · Original publication
Recorded summary
Baseline CREB activity predicted selected psychological responses to compassion-based meditation in two datasets. The same relationship was not seen for mindfulness meditation.
Recorded limitations
The study concerns prediction from baseline expression rather than a demonstrated therapy-induced transcriptional mechanism. Clinical deployment requires further validation.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Prediction analyses across two randomized trials
- assessment
- Not recorded
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://pubmed.ncbi.nlm.nih.gov/39098435/ · https://doi.org/10.1016/j.bbi.2024.08.004
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-39098435
- doi
- 10.1016/j.bbi.2024.08.004
- pmid
- 39098435
- citation Snapshot
- Not recorded
- citations By Collection
- language
- Not recorded
Complete approved library record
- id
- pmid-39098435
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Predicting psychosocial intervention response from baseline gene expression
- journal
- Brain, behavior, and immunity
- neurotransmitters
- None recorded
- year
- 2024
- authors
- Ricon-Becker I, West TN, Fredrickson BL, Kaplan DM, Mehl MR, Raison CL, Cole SW.
- design
- Prediction analyses across two randomized trials
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.1016/j.bbi.2024.08.004
- pmid
- 39098435
- urls
https://doi.org/10.1016/j.bbi.2024.08.004 · https://pubmed.ncbi.nlm.nih.gov/39098435/
- collections
language
- categories
Gene expression
- targets
- None recorded
- priority
- 0
- quotes
- None recorded
- summary
- Baseline CREB activity predicted selected psychological responses to compassion-based meditation in two datasets. The same relationship was not seen for mindfulness meditation.
- limitation
- The study concerns prediction from baseline expression rather than a demonstrated therapy-induced transcriptional mechanism. Clinical deployment requires further validation.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://pubmed.ncbi.nlm.nih.gov/39098435/ · https://doi.org/10.1016/j.bbi.2024.08.004
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- Not recorded
- topics
- None recorded
- journal Key
- brainbehaviorandimmunity
- journal Label
- Brain, behavior, and immunity
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- not-indexed
- retrieval Available
- false