Universal Informatics · Research reading room

Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.

Zheng S, Shen Y, Geng F, Ye M, Song S, Wang R, Zhang S, Ou Y, Zhou X. · European journal of psychotraumatology · 2025 · Randomized controlled trial report · double blinding not verified

Original publication · Original publication · Original publication · Original publication · Original publication

Recorded summary

The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.

Recorded limitations

Small sample, short follow-up, no attention-matched psychotherapy control and unclear assessor masking.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial report · double blinding not verified
assessment
category
rct-masking-unclear
is Randomized Controlled Trial
true
peer Reviewed
true
basis
rct
masking Roles
participants
Intervention distinguishable
providers
Unblinded
assessors
Independent of treatment; group masking not established
analysts
Not established
sources

https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

review Scope
selected-methods
trust Factor
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
masking Roles
participants
Intervention distinguishable
providers
Unblinded
assessors
Independent of treatment; group masking not established
analysts
Not established
basis
rct
sources

https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial report · double blinding not verified
intervention
Six 60-minute EMDR sessions across two weeks added to an SSRI versus SSRI alone; assessments through four weeks.
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
30 randomized and completed; 15 per arm.
population
age
12–18-year-old adolescent inpatients with depression and stressful-life-event memories.
age Fit
mixed-overlap
sample
30 randomized and completed; 15 per arm.
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-40243164
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
participants
Intervention distinguishable
providers
Unblinded
assessors
Independent of treatment; group masking not established
analysts
Not established
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

retrieved At
2026-11-02
Topics and recorded topic scores
  1. key
    vision:children
    title
    EMDR for children and adolescents
    collection
    vision
    trust Score
    2
  2. key
    vision:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    vision
    trust Score
    2
  3. key
    vision:emdr-youth
    title
    EMDR for youth
    collection
    vision
    trust Score
    2
Citation snapshot and identifiers
id
pmid-40243164
doi
10.1080/20008066.2025.2488558
pmid
40243164
citation Snapshot
count
7
source
Crossref
retrieved At
2026-10-23
citations By Collection
vision
7
Complete approved library record
lab Relevance
relationship
inspired-by
implication
Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation.
transfer Limit
Component evidence does not establish efficacy of the combined Universal Mind lab model.
institutions
None recorded
institution Evidence
None recorded
research Topics

EMDR

publication Status
pmid
40243164
checked At
2026-11-02T01:32:46.776183+00:00
pub Types

research-article · Randomized Controlled Trial · Journal Article

indexed Notices
None recorded
crossref Updates
None recorded
notice Records
None recorded
scope
Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
notice Summary
Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
randomized Study Unit Id
publication-40243164
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-02
assessment
AI assessed; human approved for publication
scope
Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
source Revision
r1-29c412dad7aa
source Content Hash
29c412dad7aaf8805a8e422544f2049cb21dba2ca46793da60ee1bec2f1ea46b
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

retrieved At
2026-11-02
study Family Id
publication-40243164
approaches

EMDR

id
pmid-40243164
aliases

youth-pmid-40243164

title
Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
journal
European journal of psychotraumatology
neurotransmitters
None recorded
year
2025
authors
Zheng S, Shen Y, Geng F, Ye M, Song S, Wang R, Zhang S, Ou Y, Zhou X.
design
Randomized controlled trial report · double blinding not verified
kind
Journal article
identity Conflict
Not recorded
doi
10.1080/20008066.2025.2488558
pmid
40243164
urls

https://doi.org/10.1080/20008066.2025.2488558 · https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

collections

vision

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.
limitation
Small sample, short follow-up, no attention-matched psychotherapy control and unclear assessor masking.
citation Count
7
citation Snapshot
count
7
source
Crossref
retrieved At
2026-10-23
study Design Assessment
category
rct-masking-unclear
is Randomized Controlled Trial
true
peer Reviewed
true
basis
rct
masking Roles
participants
Intervention distinguishable
providers
Unblinded
assessors
Independent of treatment; group masking not established
analysts
Not established
sources

https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

review Scope
selected-methods
paper Trust Assessment
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
masking Roles
participants
Intervention distinguishable
providers
Unblinded
assessors
Independent of treatment; group masking not established
analysts
Not established
basis
rct
sources

https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
citations By Collection
vision
7
topics
  1. key
    vision:children
    title
    EMDR for children and adolescents
    collection
    vision
    trust Score
    2
  2. key
    vision:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    vision
    trust Score
    2
  3. key
    vision:emdr-youth
    title
    EMDR for youth
    collection
    vision
    trust Score
    2
journal Key
europeanjournalofpsychotraumatology
journal Label
European journal of psychotraumatology
chapter Entries
  1. title
    Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
    journal
    European journal of psychotraumatology
    year
    2025
    authors
    Zheng S, Shen Y, Geng F, Ye M, Song S, Wang R, Zhang S, Ou Y, Zhou X.
    design
    Randomized controlled trial report · double blinding not verified
    urls

    https://doi.org/10.1080/20008066.2025.2488558 · https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

    doi
    10.1080/20008066.2025.2488558
    pmid
    40243164
    targets
    None recorded
    categories

    Clinical & self-report

    citation Count
    7
    citation Snapshot
    count
    7
    source
    Crossref
    retrieved At
    2026-10-23
    study Design Assessment
    category
    rct-masking-unclear
    is Randomized Controlled Trial
    true
    peer Reviewed
    true
    basis
    rct
    masking Roles
    participants
    Intervention distinguishable
    providers
    Unblinded
    assessors
    Independent of treatment; group masking not established
    analysts
    Not established
    sources

    https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

    review Scope
    selected-methods
    evidence
    evidence Type
    Randomized controlled trial report · double blinding not verified
    intervention
    Six 60-minute EMDR sessions across two weeks added to an SSRI versus SSRI alone; assessments through four weeks.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    sample
    30 randomized and completed; 15 per arm.
    population
    age
    12–18-year-old adolescent inpatients with depression and stressful-life-event memories.
    age Fit
    mixed-overlap
    sample
    30 randomized and completed; 15 per arm.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    measurement
    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    publication-40243164
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
    None recorded
    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    masking Roles
    participants
    Intervention distinguishable
    providers
    Unblinded
    assessors
    Independent of treatment; group masking not established
    analysts
    Not established
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

    retrieved At
    2026-11-02
    record Id
    pmid-40243164
    quotes
    None recorded
    source Pages
    None recorded
    summary
    The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.
    limitation
    Small sample, short follow-up, no attention-matched psychotherapy control and unclear assessor masking.
    id
    vision-children-pmid-40243164
    paper Trust Assessment
    score
    2
    display Crosses
    2
    scope
    Paper
    status
    assessed
    rating Scale
    library-trust-factor/1-3
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    masking Roles
    participants
    Intervention distinguishable
    providers
    Unblinded
    assessors
    Independent of treatment; group masking not established
    analysts
    Not established
    basis
    rct
    sources

    https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

    assessed At
    2026-11-02
    review Scope
    selected-methods
    human Approval
    false
    review Limit
    AI source-based design assessment; human content sign-off is recorded separately.
    collections

    vision

    origin
    approved-youth-20261102
    priority
    1
    kind
    Journal article
    jadad
    status
    unassessed
    score
    Not recorded
    research Group
    children
    finding
    The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.
    legacy Article Stars
    Not recorded
    legacy Rating Basis
    Not recorded
    stars
    2
    rating Basis
    Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
    aliases

    youth-pmid-40243164

    archive Entries
    None recorded
    neurotransmitters
    None recorded
    conditions

    depression · stress

    condition Evidence
    1. id
      depression
      evidence
      1. field
        title
        text
        Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
        matched Text
        depressive
      2. field
        findings
        text
        The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.
        matched Text
        depression
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    2. id
      stress
      evidence
      1. field
        title
        text
        Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
        matched Text
        stress
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    age Groups

    adolescents · youth

    age Population
    record Id
    pmid-40243164
    collections

    vision

    groups

    adolescents · youth

    reported Ages
    12–18-year-old adolescent inpatients with depression and stressful-life-event memories.
    youth Scope
    included
    youth Source Note
    The existing youth filter includes adolescents and source-defined young people. It does not establish a separate 16–24 estimate.
    age Fit
    mixed-overlap
    source URL
    https://pubmed.ncbi.nlm.nih.gov/40243164/
    basis Type
    selected-methods-ai-editorial-assessment
    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
    community Matches
    None recorded
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-02
    assessment
    AI assessed; human approved for publication
    scope
    Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
    source Revision
    r1-29c412dad7aa
    source Content Hash
    29c412dad7aaf8805a8e422544f2049cb21dba2ca46793da60ee1bec2f1ea46b
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

    retrieved At
    2026-11-02
    study Family Id
    publication-40243164
    randomized Study Unit Id
    publication-40243164
    institutions
    None recorded
    institution Evidence
    None recorded
    research Topics

    EMDR

    lab Relevance
    relationship
    inspired-by
    implication
    Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
    40243164
    checked At
    2026-11-02T01:32:46.776183+00:00
    pub Types

    research-article · Randomized Controlled Trial · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    EMDR

    assessment Record
    id
    youth-pmid-40243164
    title
    Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
    authors
    Zheng S, Shen Y, Geng F, Ye M, Song S, Wang R, Zhang S, Ou Y, Zhou X.
    year
    2025
    journal
    European journal of psychotraumatology
    doi
    10.1080/20008066.2025.2488558
    pmid
    40243164
    pmcid
    PMC12006939
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    EMDR

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    research-article · Randomized Controlled Trial · Journal Article

    study Family Id
    publication-40243164
    randomized Study Unit Id
    publication-40243164
    existing Repository Matches
    1. id
      pmid-40243164
      matched By

      PMID · DOI · normalized exact title

      collections

      vision

    population
    age
    12–18-year-old adolescent inpatients with depression and stressful-life-event memories.
    age Fit
    mixed-overlap
    sample
    30 randomized and completed; 15 per arm.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    Six 60-minute EMDR sessions across two weeks added to an SSRI versus SSRI alone; assessments through four weeks.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    rct
    category
    randomized-report
    randomization Methods Inspected
    true
    masking
    participants
    Intervention distinguishable
    providers
    Unblinded
    assessors
    Independent of treatment; group masking not established
    analysts
    Not established
    double Blinding Verified
    false
    proposed Crosses
    2
    approved Crosses
    Not recorded
    findings
    The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.
    limitations
    Small sample, short follow-up, no attention-matched psychotherapy control and unclear assessor masking.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    lab Relevance
    relationship
    inspired-by
    implication
    Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    sources
    1. type
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      url
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      url
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      retrieved At
      2026-11-02
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      url
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    4. type
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      url
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    pmid
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    checked At
    2026-11-02T01:32:46.776183+00:00
    pub Types

    research-article · Randomized Controlled Trial · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
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    indexed Notices
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    crossref Updates
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    notice Records
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    scope
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    notice Summary
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    legacy Rating Basis
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    stars
    2
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    Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
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    institution Evidence
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    publication Type

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    study Family Id
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    scope
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    title
    Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
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    Zheng S, Shen Y, Geng F, Ye M, Song S, Wang R, Zhang S, Ou Y, Zhou X.
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      1. field
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        text
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        matched Text
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    retrieved At
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    study Family Id
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    institutions
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    institution Evidence
    None recorded
    research Topics

    EMDR

    lab Relevance
    relationship
    inspired-by
    implication
    Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
    40243164
    checked At
    2026-11-02T01:32:46.776183+00:00
    pub Types

    research-article · Randomized Controlled Trial · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    EMDR

    record Id
    pmid-40243164
    source Pages
    None recorded
    research Group
    children
    legacy Article Stars
    Not recorded
    legacy Rating Basis
    Not recorded
    stars
    2
    rating Basis
    Publication identity and reported study design checked. Outcome blinding is not established in the material reviewed; no single- or double-blind RCT classification is assigned.
    archive Entries
    None recorded
    assessment Record
    id
    youth-pmid-40243164
    title
    Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
    authors
    Zheng S, Shen Y, Geng F, Ye M, Song S, Wang R, Zhang S, Ou Y, Zhou X.
    year
    2025
    journal
    European journal of psychotraumatology
    doi
    10.1080/20008066.2025.2488558
    pmid
    40243164
    pmcid
    PMC12006939
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    EMDR

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    research-article · Randomized Controlled Trial · Journal Article

    study Family Id
    publication-40243164
    randomized Study Unit Id
    publication-40243164
    existing Repository Matches
    1. id
      pmid-40243164
      matched By

      PMID · DOI · normalized exact title

      collections

      vision

    population
    age
    12–18-year-old adolescent inpatients with depression and stressful-life-event memories.
    age Fit
    mixed-overlap
    sample
    30 randomized and completed; 15 per arm.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    Six 60-minute EMDR sessions across two weeks added to an SSRI versus SSRI alone; assessments through four weeks.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    rct
    category
    randomized-report
    randomization Methods Inspected
    true
    masking
    participants
    Intervention distinguishable
    providers
    Unblinded
    assessors
    Independent of treatment; group masking not established
    analysts
    Not established
    double Blinding Verified
    false
    proposed Crosses
    2
    approved Crosses
    Not recorded
    findings
    The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.
    limitations
    Small sample, short follow-up, no attention-matched psychotherapy control and unclear assessor masking.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    lab Relevance
    relationship
    inspired-by
    implication
    Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    sources
    1. type
      primary bibliographic record
      url
      https://pubmed.ncbi.nlm.nih.gov/40243164/
      retrieved At
      2026-11-02
      sha256
      e79866b50b924dec95fbe5b9818ed56dbe41e9371abdf5f4a1bd53adbf76fd19
      hash Scope
      normalized Europe PMC core metadata snapshot
    2. type
      publisher DOI
      url
      https://doi.org/10.1080/20008066.2025.2488558
      retrieved At
      2026-11-02
    3. type
      PMC article
      url
      https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/
      retrieved At
      2026-11-02
      access
      Full text cached
    4. type
      full-text-xml
      url
      https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML
      retrieved At
      2026-11-02T00:59:12.911130+00:00
      sha256
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      DOI-metadata
      url
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      retrieved At
      2026-11-02T00:59:12.914333+00:00
      sha256
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    publication Status
    pmid
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    checked At
    2026-11-02T01:32:46.776183+00:00
    pub Types

    research-article · Randomized Controlled Trial · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    review Ready
    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
    review
    status
    pending
    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
    false
    approved Retrieval Eligible
    false
    selected Corpus References
    None recorded
    reference Scope
    Explicit publisher reference identifiers; citation is not proof of inclusion in a meta-analysis.
    content Hash
    29c412dad7aaf8805a8e422544f2049cb21dba2ca46793da60ee1bec2f1ea46b
    revision
    r1-29c412dad7aa
    collection
    vision
    chapter Number
    8
    topic Id
    emdr-youth
    topic Title
    EMDR for youth
    trust Score
    2
evidence
evidence Type
Randomized controlled trial report · double blinding not verified
intervention
Six 60-minute EMDR sessions across two weeks added to an SSRI versus SSRI alone; assessments through four weeks.
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
30 randomized and completed; 15 per arm.
population
age
12–18-year-old adolescent inpatients with depression and stressful-life-event memories.
age Fit
mixed-overlap
sample
30 randomized and completed; 15 per arm.
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-40243164
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Supports a clinically governed referral/treatment research question; does not validate generic EMDR-like stimulation. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
participants
Intervention distinguishable
providers
Unblinded
assessors
Independent of treatment; group masking not established
analysts
Not established
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/40243164/ · https://doi.org/10.1080/20008066.2025.2488558 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12006939/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12006939/fullTextXML · https://api.crossref.org/works/10.1080%2F20008066.2025.2488558

retrieved At
2026-11-02
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    depression
    evidence
    1. field
      title
      text
      Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
      matched Text
      depressive
    2. field
      findings
      text
      The add-on EMDR arm improved more on depression, event-related distress and rumination over time. This tests EMDR with medication and hospital care, not stand-alone treatment or a community wellbeing activity.
      matched Text
      depression
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
  2. id
    stress
    evidence
    1. field
      title
      text
      Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.
      matched Text
      stress
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
conditions

depression · stress

topic Trust Scores

2

full Text
status
not-indexed
retrieval Available
false

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