The Effectiveness of Eye Movement Desensitization and Reprocessing Therapy on Post-Traumatic Stress Disorder Symptoms and Diagnostic Status in Patients with a Personality Disorder: A Randomized Controlled Trial.
Hafkemeijer L, Hofman S, de Jongh A, de Roos D, van Velzen M, Starrenburg A, Slotema K. · Psychotherapy and psychosomatics · 2025 · Randomized controlled trial
Original publication · Original publication · Original publication
Recorded summary
In 159 people with personality disorders, EMDR reduced PTSD symptoms more than a waitlist. Among participants with PTSD receiving EMDR, 65.5% no longer met the diagnosis after treatment and 73.1% at follow-up.
Recorded limitations
A waitlist does not control for therapeutic attention. The remission percentages describe the treated subgroup; they are not an absolute treatment effect or a general remission guarantee.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Therapist-delivered EMDR
- comparator
- Waitlist
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/h747ggnb · https://europepmc.org/article/MED/40716437
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
- key
- vision:i
- title
- EMDR for PTSD and related mental-health outcomes
- collection
- vision
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-40716437
- doi
- 10.1159/000547622
- pmid
- 40716437
- citation Snapshot
- count
- 2
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/40716437
- citations By Collection
- vision
- 2
Complete approved library record
- id
- pmid-40716437
- publication Key
- doi:10.1159/000547622
- aliases
- None recorded
- title
- The Effectiveness of Eye Movement Desensitization and Reprocessing Therapy on Post-Traumatic Stress Disorder Symptoms and Diagnostic Status in Patients with a Personality Disorder: A Randomized Controlled Trial.
- journal
- Psychotherapy and psychosomatics
- neurotransmitters
- None recorded
- year
- 2025
- authors
- Hafkemeijer L, Hofman S, de Jongh A, de Roos D, van Velzen M, Starrenburg A, Slotema K.
- design
- Randomized controlled trial
- identity Conflict
- Not recorded
- doi
- 10.1159/000547622
- pmid
- 40716437
- urls
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- collections
vision
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- In 159 people with personality disorders, EMDR reduced PTSD symptoms more than a waitlist. Among participants with PTSD receiving EMDR, 65.5% no longer met the diagnosis after treatment and 73.1% at follow-up.
- limitation
- A waitlist does not control for therapeutic attention. The remission percentages describe the treated subgroup; they are not an absolute treatment effect or a general remission guarantee.
- citation Count
- 2
- citation Snapshot
- count
- 2
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/40716437
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- 2
- topics
- key
- vision:i
- title
- EMDR for PTSD and related mental-health outcomes
- collection
- vision
- trust Score
- 2
- journal Key
- psychotherapyandpsychosomatics
- journal Label
- Psychotherapy and psychosomatics
- chapter Entries
- title
- The Effectiveness of Eye Movement Desensitization and Reprocessing Therapy on Post-Traumatic Stress Disorder Symptoms and Diagnostic Status in Patients with a Personality Disorder: A Randomized Controlled Trial.
- journal
- Psychotherapy and psychosomatics
- year
- 2025
- authors
- Hafkemeijer L, Hofman S, de Jongh A, de Roos D, van Velzen M, Starrenburg A, Slotema K.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- doi
- 10.1159/000547622
- pmid
- 40716437
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 2
- citation Snapshot
- count
- 2
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/40716437
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Therapist-delivered EMDR
- comparator
- Waitlist
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/h747ggnb · https://europepmc.org/article/MED/40716437
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- id
- vision-i-pmid-40716437
- record Id
- pmid-40716437
- quotes
- None recorded
- source Pages
- None recorded
- summary
- In 159 people with personality disorders, EMDR reduced PTSD symptoms more than a waitlist. Among participants with PTSD receiving EMDR, 65.5% no longer met the diagnosis after treatment and 73.1% at follow-up.
- limitation
- A waitlist does not control for therapeutic attention. The remission percentages describe the treated subgroup; they are not an absolute treatment effect or a general remission guarantee.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1159/000547622
- collection
- vision
- chapter Number
- 1
- topic Id
- i
- topic Title
- EMDR for PTSD and related mental-health outcomes
- trust Score
- 2
- evidence
- intervention
- Therapist-delivered EMDR
- comparator
- Waitlist
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/40716437/ · https://doi.org/10.1159/000547622 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12503563/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/h747ggnb · https://europepmc.org/article/MED/40716437
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- ptsd
- evidence
- field
- curated primary-source summary
- text
- In 159 people with personality disorders, EMDR reduced PTSD symptoms more than a waitlist. Among participants with PTSD receiving EMDR, 65.5% no longer met the diagnosis after treatment and 73.1% at follow-up.
- matched Text
- ptsd
- conditions
ptsd
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false