Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls
Gómez-Carballa A, Navarro L, Mallah NEZ, Bello X, Pischedda S, Viz-Lasheras S, Currás MJ, Ferreirós-Vidal I, Mallah N, Montoto-Louzao J, Camino-Mera A, Castelo-Martínez L, Rey-Vázquez S, Redondo L, Dacosta-Urbieta A, Rivero-Calle I, Rodríguez-Tenreiro C, Martinón-Torres F, Salas A. · Frontiers in Aging Neuroscience · 2025 · Human before–after targeted transcriptomic study
Original publication · Original publication · Original publication
Recorded summary
Brief music exposure was associated with differing buccal expression responses in cognitive-disorder patients and controls. Highlighted genes included LGALS3, CXCL8 and THOP1.
Recorded limitations
Peripheral tissue and exploratory comparisons; the results do not establish changes in brain tissue or therapeutic efficacy.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Human before–after targeted transcriptomic study
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/41064114/ · https://doi.org/10.3389/fnagi.2025.1622816
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
None recordedCitation snapshot and identifiers
- id
- pmid-41064114
- doi
- 10.3389/fnagi.2025.1622816
- pmid
- 41064114
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- Not recorded
Complete approved library record
- id
- pmid-41064114
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls
- journal
- Frontiers in Aging Neuroscience
- publisher Family
- frontiers
- publisher Family Label
- Frontiers
- neurotransmitters
- None recorded
- year
- 2025
- authors
- Gómez-Carballa A, Navarro L, Mallah NEZ, Bello X, Pischedda S, Viz-Lasheras S, Currás MJ, Ferreirós-Vidal I, Mallah N, Montoto-Louzao J, Camino-Mera A, Castelo-Martínez L, Rey-Vázquez S, Redondo L, Dacosta-Urbieta A, Rivero-Calle I, Rodríguez-Tenreiro C, Martinón-Torres F, Salas A.
- design
- Human before–after targeted transcriptomic study
- kind
- Journal article
- identity Conflict
- Not recorded
- doi
- 10.3389/fnagi.2025.1622816
- pmid
- 41064114
- urls
https://doi.org/10.3389/fnagi.2025.1622816 · https://pmc.ncbi.nlm.nih.gov/articles/PMC12501983/ · https://pubmed.ncbi.nlm.nih.gov/41064114/
- collections
sound
- categories
Gene expression
- targets
- None recorded
- priority
- 0
- quotes
- None recorded
- summary
- Brief music exposure was associated with differing buccal expression responses in cognitive-disorder patients and controls. Highlighted genes included LGALS3, CXCL8 and THOP1.
- limitation
- Peripheral tissue and exploratory comparisons; the results do not establish changes in brain tissue or therapeutic efficacy.
- citation Count
- Not recorded
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/41064114/ · https://doi.org/10.3389/fnagi.2025.1622816
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- Not recorded
- topics
- None recorded
- journal Key
- frontiersinagingneuroscience
- journal Label
- Frontiers in Aging Neuroscience
- chapter Entries
- None recorded
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
- None recorded
- full Text
- status
- open-license
- retrieval Available
- true
- url
- https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12501983/fullTextXML
- pmcid
- PMC12501983
- rights
- license
- CC BY (version not specified in article)
- statement
Copyright © 2025 Gómez-Carballa, Navarro, Mallah, Bello, Pischedda, Viz-Lasheras, Currás, Ferreirós-Vidal, Mallah, Montoto-Louzao, Camino-Mera, Castelo-Martínez, Rey-Vázquez, Redondo, Dacosta-Urbieta, Rivero-Calle, Rodríguez-Tenreiro, Martinón-Torres and Salas. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- sha256
- 5dcfb8d4def74b4efc467bb2b3ce14d766a614477da5676a4f9ade64f16f4cb2
- checked At
- 2026-10-24