Mindfulness Development via Biofeedback for Anxiety in Hospitalized Patients: A Randomized Controlled Trial
Kotelnikova Anastasia V., Ruzinova Vera M., Kiseleva Maria G., Volel Beatrice, Kukshina Anastasia A. · Brain Sciences · 2026 · Randomised controlled study
Recorded summary
A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
Recorded limitations
Auditory feedback followed EEG alpha power. A separate training stage varied audiovisual feedback with current heart rate. A psychiatrist masked to allocation rated anxiety.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomised controlled study
- assessment
- category
- single-blind-rct
- peer Reviewed
- true
- basis
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- sources
https://doi.org/10.3390/brainsci16070748
- is Randomized Controlled Trial
- true
- masking Roles
- The independent psychiatrist assessing anxiety was masked. Participants and treating therapists knew the assigned intervention.
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- single
- peer Reviewed
- true
- basis
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- sources
https://pubmed.ncbi.nlm.nih.gov/42512522/ · https://doi.org/10.3390/brainsci16070748
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-11-05
- display Crosses
- 2
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- evidence Type
- Participant study
- measurement
- EEG · Heart rate / heartbeat
- relationship Note
- Auditory feedback followed EEG alpha power. A separate training stage varied audiovisual feedback with current heart rate. A psychiatrist masked to allocation rated anxiety.
Topics and recorded topic scores
- key
- language:mindfulness-biofeedback
- title
- Mindfulness Biofeedback / AR / VR / Mixed Reality
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-42512522
- doi
- 10.3390/brainsci16070748
- pmid
- 42512522
- citation Snapshot
- Not recorded
- citations By Collection
- language
- Not recorded
Complete approved library record
- id
- pmid-42512522
- aliases
- None recorded
- title
- Mindfulness Development via Biofeedback for Anxiety in Hospitalized Patients: A Randomized Controlled Trial
- journal
- Brain Sciences
- neurotransmitters
- None recorded
- year
- 2026
- authors
- Kotelnikova Anastasia V., Ruzinova Vera M., Kiseleva Maria G., Volel Beatrice, Kukshina Anastasia A.
- design
- Randomised controlled study
- identity Conflict
- Not recorded
- doi
- 10.3390/brainsci16070748
- pmid
- 42512522
- urls
https://doi.org/10.3390/brainsci16070748
- collections
language
- categories
Mindfulness and biofeedback
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- limitation
- Auditory feedback followed EEG alpha power. A separate training stage varied audiovisual feedback with current heart rate. A psychiatrist masked to allocation rated anxiety.
- citation Count
- Not recorded
- study Design Assessment
- category
- single-blind-rct
- peer Reviewed
- true
- basis
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- sources
https://doi.org/10.3390/brainsci16070748
- is Randomized Controlled Trial
- true
- masking Roles
- The independent psychiatrist assessing anxiety was masked. Participants and treating therapists knew the assigned intervention.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- single
- peer Reviewed
- true
- basis
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- sources
https://pubmed.ncbi.nlm.nih.gov/42512522/ · https://doi.org/10.3390/brainsci16070748
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-11-05
- display Crosses
- 2
- citations By Collection
- language
- Not recorded
- topics
- key
- language:mindfulness-biofeedback
- title
- Mindfulness Biofeedback / AR / VR / Mixed Reality
- collection
- language
- trust Score
- 2
- journal Key
- brainsciences
- journal Label
- Brain Sciences
- chapter Entries
- title
- Mindfulness Development via Biofeedback for Anxiety in Hospitalized Patients: A Randomized Controlled Trial
- doi
- 10.3390/brainsci16070748
- pmid
- 42512522
- journal
- Brain Sciences
- year
- 2026
- authors
- Kotelnikova Anastasia V., Ruzinova Vera M., Kiseleva Maria G., Volel Beatrice, Kukshina Anastasia A.
- design
- Randomised controlled study
- urls
https://doi.org/10.3390/brainsci16070748
- targets
- None recorded
- categories
Mindfulness and biofeedback
- citation Count
- Not recorded
- evidence
- evidence Type
- Participant study
- measurement
- EEG · Heart rate / heartbeat
- relationship Note
- Auditory feedback followed EEG alpha power. A separate training stage varied audiovisual feedback with current heart rate. A psychiatrist masked to allocation rated anxiety.
- id
- language-biofeedback-18
- record Id
- pmid-42512522
- summary
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- limitation
- Auditory feedback followed EEG alpha power. A separate training stage varied audiovisual feedback with current heart rate. A psychiatrist masked to allocation rated anxiety.
- quotes
- None recorded
- source Pages
- None recorded
- study Design Assessment
- category
- single-blind-rct
- peer Reviewed
- true
- basis
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- sources
https://doi.org/10.3390/brainsci16070748
- is Randomized Controlled Trial
- true
- masking Roles
- The independent psychiatrist assessing anxiety was masked. Participants and treating therapists knew the assigned intervention.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- single
- peer Reviewed
- true
- basis
- A randomised study of 188 inpatients compared biofeedback, medication and their combination. Anxiety improved more in the biofeedback arms than with medication alone in the per-protocol analysis. Registration was retrospective and the setting was inpatient care.
- sources
https://pubmed.ncbi.nlm.nih.gov/42512522/ · https://doi.org/10.3390/brainsci16070748
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-11-05
- display Crosses
- 2
- collection
- language
- chapter Number
- 2
- topic Id
- mindfulness-biofeedback
- topic Title
- Mindfulness Biofeedback / AR / VR / Mixed Reality
- trust Score
- 2
- evidence
- evidence Type
- Participant study
- measurement
- EEG · Heart rate / heartbeat
- relationship Note
- Auditory feedback followed EEG alpha power. A separate training stage varied audiovisual feedback with current heart rate. A psychiatrist masked to allocation rated anxiety.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false