Eye movement desensitisation and reprocessing for post-traumatic stress in survivors of critical illness (EMERALD): a mixed-methods, randomised, single-blind, parallel group-controlled, feasibility trial.
Bates A, Cusack R, Golding H, Moyses H, Southam H, Rushbrook S, Highfield J, Pattison N, Baldwin DS, Grocott MPW. · EClinicalMedicine · 2026 · Single-blind randomized feasibility trial
Original publication · Original publication · Original publication
Recorded summary
The 40-person EMERALD trial in critical-illness survivors achieved 98% clinician-rated follow-up at 12 months. Exploratory PTSD symptom change favoured EMDR plus usual care by 14.1 points, with a 95% confidence interval of 6.2 to 22.0 points.
Recorded limitations
Feasibility, acceptability and safety were the primary objectives. The symptom estimate is hypothesis-generating and does not establish definitive treatment effectiveness.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Single-blind randomized feasibility trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- single
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Therapist-delivered EMDR
- comparator
- Treatment as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/t73vb9kv · https://europepmc.org/article/MED/42518933
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT05591625
Topics and recorded topic scores
- key
- vision:i
- title
- EMDR for PTSD and related mental-health outcomes
- collection
- vision
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-42518933
- doi
- 10.1016/j.eclinm.2026.104082
- pmid
- 42518933
- citation Snapshot
- count
- 1
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/42518933
- citations By Collection
- vision
- 1
Complete approved library record
- id
- pmid-42518933
- publication Key
- doi:10.1016/j.eclinm.2026.104082
- aliases
- None recorded
- title
- Eye movement desensitisation and reprocessing for post-traumatic stress in survivors of critical illness (EMERALD): a mixed-methods, randomised, single-blind, parallel group-controlled, feasibility trial.
- journal
- EClinicalMedicine
- neurotransmitters
- None recorded
- year
- 2026
- authors
- Bates A, Cusack R, Golding H, Moyses H, Southam H, Rushbrook S, Highfield J, Pattison N, Baldwin DS, Grocott MPW.
- design
- Single-blind randomized feasibility trial
- identity Conflict
- Not recorded
- doi
- 10.1016/j.eclinm.2026.104082
- pmid
- 42518933
- urls
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- collections
vision
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- The 40-person EMERALD trial in critical-illness survivors achieved 98% clinician-rated follow-up at 12 months. Exploratory PTSD symptom change favoured EMDR plus usual care by 14.1 points, with a 95% confidence interval of 6.2 to 22.0 points.
- limitation
- Feasibility, acceptability and safety were the primary objectives. The symptom estimate is hypothesis-generating and does not establish definitive treatment effectiveness.
- citation Count
- 1
- citation Snapshot
- count
- 1
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/42518933
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- single
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- vision
- 1
- topics
- key
- vision:i
- title
- EMDR for PTSD and related mental-health outcomes
- collection
- vision
- trust Score
- 2
- journal Key
- eclinicalmedicine
- journal Label
- EClinicalMedicine
- chapter Entries
- title
- Eye movement desensitisation and reprocessing for post-traumatic stress in survivors of critical illness (EMERALD): a mixed-methods, randomised, single-blind, parallel group-controlled, feasibility trial.
- journal
- EClinicalMedicine
- year
- 2026
- authors
- Bates A, Cusack R, Golding H, Moyses H, Southam H, Rushbrook S, Highfield J, Pattison N, Baldwin DS, Grocott MPW.
- design
- Single-blind randomized feasibility trial
- urls
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- doi
- 10.1016/j.eclinm.2026.104082
- pmid
- 42518933
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 1
- citation Snapshot
- count
- 1
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/42518933
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Therapist-delivered EMDR
- comparator
- Treatment as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/t73vb9kv · https://europepmc.org/article/MED/42518933
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT05591625
- id
- vision-i-pmid-42518933
- record Id
- pmid-42518933
- quotes
- None recorded
- source Pages
- None recorded
- summary
- The 40-person EMERALD trial in critical-illness survivors achieved 98% clinician-rated follow-up at 12 months. Exploratory PTSD symptom change favoured EMDR plus usual care by 14.1 points, with a 95% confidence interval of 6.2 to 22.0 points.
- limitation
- Feasibility, acceptability and safety were the primary objectives. The symptom estimate is hypothesis-generating and does not establish definitive treatment effectiveness.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- single
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1016/j.eclinm.2026.104082
- collection
- vision
- chapter Number
- 1
- topic Id
- i
- topic Title
- EMDR for PTSD and related mental-health outcomes
- trust Score
- 2
- evidence
- intervention
- Therapist-delivered EMDR
- comparator
- Treatment as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/42518933/ · https://doi.org/10.1016/j.eclinm.2026.104082 · https://pmc.ncbi.nlm.nih.gov/articles/PMC13382324/
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/t73vb9kv · https://europepmc.org/article/MED/42518933
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- trial Id
- NCT05591625
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- ptsd
- evidence
- field
- curated primary-source summary
- text
- The 40-person EMERALD trial in critical-illness survivors achieved 98% clinician-rated follow-up at 12 months. Exploratory PTSD symptom change favoured EMDR plus usual care by 14.1 points, with a 95% confidence interval of 6.2 to 22.0 points.
- matched Text
- ptsd
- conditions
ptsd
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false