Effectiveness and Cost-Effectiveness of a Digital Mindfulness-Based Intervention for Psychological Distress Delivered by Trainee Instructors: A Randomized Controlled Trial.
Chen D, Gomzyakova E, Gu Y, Zhang Y, Hofmann SG, Liu X. · Psychotherapy and psychosomatics · 2026 · Randomized controlled trial
Original publication · Original publication
Recorded summary
In 1,281 adults with substantial psychological distress, an eight-week hybrid digital mindfulness programme plus usual services reduced distress more than usual services alone, with an effect size of approximately 0.53.
Recorded limitations
Follow-up ended at eight weeks, and economic estimates reflect the trial's Chinese service context. Longer-term durability and transfer to other settings remain untested.
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- Randomized controlled trial
- assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- intervention
- Eight-week hybrid digital mindfulness programme
- comparator
- Services as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/9phc8gz8 · https://europepmc.org/article/MED/42599846
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
Topics and recorded topic scores
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- pmid-42599846
- doi
- 10.1159/000553463
- pmid
- 42599846
- citation Snapshot
- count
- 0
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/42599846
- citations By Collection
- language
- 0
Complete approved library record
- id
- pmid-42599846
- publication Key
- doi:10.1159/000553463
- aliases
- None recorded
- title
- Effectiveness and Cost-Effectiveness of a Digital Mindfulness-Based Intervention for Psychological Distress Delivered by Trainee Instructors: A Randomized Controlled Trial.
- journal
- Psychotherapy and psychosomatics
- neurotransmitters
- None recorded
- year
- 2026
- authors
- Chen D, Gomzyakova E, Gu Y, Zhang Y, Hofmann SG, Liu X.
- design
- Randomized controlled trial
- identity Conflict
- Not recorded
- doi
- 10.1159/000553463
- pmid
- 42599846
- urls
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- collections
language
- categories
Clinical & self-report
- targets
- None recorded
- priority
- 1
- quotes
- None recorded
- summary
- In 1,281 adults with substantial psychological distress, an eight-week hybrid digital mindfulness programme plus usual services reduced distress more than usual services alone, with an effect size of approximately 0.53.
- limitation
- Follow-up ended at eight weeks, and economic estimates reflect the trial's Chinese service context. Longer-term durability and transfer to other settings remain untested.
- citation Count
- 0
- citation Snapshot
- count
- 0
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/42599846
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 0
- topics
- key
- language:mindfulness-clinical
- title
- Mindfulness-based interventions: controlled clinical trials
- collection
- language
- trust Score
- 2
- journal Key
- psychotherapyandpsychosomatics
- journal Label
- Psychotherapy and psychosomatics
- chapter Entries
- title
- Effectiveness and Cost-Effectiveness of a Digital Mindfulness-Based Intervention for Psychological Distress Delivered by Trainee Instructors: A Randomized Controlled Trial.
- journal
- Psychotherapy and psychosomatics
- year
- 2026
- authors
- Chen D, Gomzyakova E, Gu Y, Zhang Y, Hofmann SG, Liu X.
- design
- Randomized controlled trial
- urls
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- doi
- 10.1159/000553463
- pmid
- 42599846
- targets
- None recorded
- categories
Clinical & self-report
- citation Count
- 0
- citation Snapshot
- count
- 0
- source
- Europe PMC
- retrieved At
- 2026-10-26
- url
- https://europepmc.org/article/MED/42599846
- study Design Assessment
- category
- peer-reviewed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- assessed At
- 2026-10-26
- registered Masking Basis
- false
- evidence
- intervention
- Eight-week hybrid digital mindfulness programme
- comparator
- Services as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/9phc8gz8 · https://europepmc.org/article/MED/42599846
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- id
- language-mindfulness-clinical-pmid-42599846
- record Id
- pmid-42599846
- quotes
- None recorded
- source Pages
- None recorded
- summary
- In 1,281 adults with substantial psychological distress, an eight-week hybrid digital mindfulness programme plus usual services reduced distress more than usual services alone, with an effect size of approximately 0.53.
- limitation
- Follow-up ended at eight weeks, and economic estimates reflect the trial's Chinese service context. Longer-term durability and transfer to other settings remain untested.
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- true
- basis
- Reported design checked against the primary publication abstract. Blinding terminology reflects the source report, not an independent risk-of-bias rating.
- sources
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- publication Key
- doi:10.1159/000553463
- collection
- language
- chapter Number
- 4
- topic Id
- mindfulness-clinical
- topic Title
- Mindfulness-based interventions: controlled clinical trials
- trust Score
- 2
- evidence
- intervention
- Eight-week hybrid digital mindfulness programme
- comparator
- Services as usual
- evidence Type
- Clinical or experimental outcomes
- source URLs
https://pubmed.ncbi.nlm.nih.gov/42599846/ · https://doi.org/10.1159/000553463
- checked At
- 2026-10-26
- review Scope
- Primary publication abstract and bibliographic identity checked; comprehensive full-text risk-of-bias and Jadad assessment pending.
- discovery Sources
https://daytab.com/study/9phc8gz8 · https://europepmc.org/article/MED/42599846
- selection Policy
- Success-focused discovery selection, with material limitations retained; not an exhaustive systematic review.
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- stress
- evidence
- field
- curated primary-source summary
- text
- In 1,281 adults with substantial psychological distress, an eight-week hybrid digital mindfulness programme plus usual services reduced distress more than usual services alone, with an effect size of approximately 0.53.
- matched Text
- stress
- conditions
stress
- topic Trust Scores
2
- full Text
- status
- not-indexed
- retrieval Available
- false